The 2016 CT state EMS protocol update emphasizes minimally interrupted, high-quality CPR. It changes adult CPR to continuous compressions for 2 minutes without pausing for breaths. For cardiac arrests, CCR is recommended for the first 8 minutes using passive ventilation before transitioning to active ventilations. Resuscitation should be performed on scene until ROSC or termination of efforts, except in special circumstances. The protocol introduces team-focused CPR with designated compressor, airway, and vascular roles to optimize efficiency. It also provides a CPR checklist for the code commander. Mechanical CPR may be considered in settings where high-quality manual CPR is difficult.
Associate Professor Vincent Pellegrino is a Senior Intensive Care Specialist at The Alfred Hospital and head of the ECMO Clinical Service. He has had a lead role in the development of ECMO services at The Alfred since 2003. From the ECMO CPR ICN Victoria meeting he discusses how to get patient selection and outcomes right for eCPR.
Associate Professor Vincent Pellegrino is a Senior Intensive Care Specialist at The Alfred Hospital and head of the ECMO Clinical Service. He has had a lead role in the development of ECMO services at The Alfred since 2003. From the ECMO CPR ICN Victoria meeting he discusses how to get patient selection and outcomes right for eCPR.
Steve Bernard speaks at a meeting on 4/2/14 in Sydney on the reality of ECMO CPR at The Alfred in Melbourne, Victoria, and the upcoming CHEER study.
Exciting times!
See Intensive Care Network for the talk and more.
ATLS is two days course for those who manage trauma patients. These protocols have been followed by hospitals all over the world to treat trauma patients quickly and efficiently.
Slides for a talk by Vincent Pellegrino (ECMO Director at The Alfred ICU) on ECPR. For videocast and audio only versions of this talk go to the RAGE podcast (http://ragepodcast.com/ecpr-vincent-pellegrino/) or The Alfred ICU's INTENSIVE blog (http://intensiveblog.com/ecpr-vin-pellegrino/).
A ventilator mode can be thought of as a classification based on how to control the ventilator breath.
Traditionally ventilators were classified based on how they determined when to stop giving a breath.
Control mode ventilation
Assist mode ventilation
Assist/control mode ventilation
Intermittent mandatory ventilation
Pressure support ventilation
PEEP
CPAP
Mandatory minute ventilation (MMV)
High frequency ventilation
Airway pressure release ventilation
Inverse ratio ventilation
Continuous flow apneic ventilation
Differential lung ventilation
Proportional assist ventilation
Neurally adjusted ventilatory assist (NAVA)
Extracorporeal membrane oxygenation
Name , basic/advanced mode
Type- control, assist, partial assist, spontaneous
Phase variables
Mechanics
Clinical indications
Advantages
Disadvantages
Graphics
Basic mode- volume preset, patient does not participate in any phase of the ventilation cycle.
Time triggered, volume limited, time/volume cycled.
Full support mode– hence advantageous in critically ill patients who require a guaranteed minute ventilation
Reduces respiratory WOB and minimizes oxygen consumption of respiratory muscles
Used in
After 1st intubation, prior to full evaluation
Patients who require high minute ventilation
Patients with unstable respiratory drives
Patients with respiratory muscle fatigue
Patients with poor cardiac output to reduce oxygen consumption of resp. muscles
Two modes– volume cycled, pressure cycled
A ventilator mode can be thought of as a classification based on how to control the ventilator breath.
Traditionally ventilators were classified based on how they determined when to stop giving a breath.
Mechanical ventilation ppt including airway, ventilator, tubings and connections, nursing management, trouble shooting common problems and issues, suctioning etc.
A brief yet comprehensive coverage of ICU role in ECMO cases. Presentation has been prepared in order to help ICU fellows and registrars to understand the importance of their role and to know necessary actions they have to take in case of need.
Brief Overview – ACLS Algorithm
Rhythm Based Management of Cardiac Arrest.
Monitoring during CPR.
Access for Parenteral Medications during Cardiac Arrest.
Advanced Airway.
Medications for Arrest Rythms.
Interventions Not Recommended for Routine Use During Cardiac Arrest.
Explore our infographic on 'Essential Metrics for Palliative Care Management' which highlights key performance indicators crucial for enhancing the quality and efficiency of palliative care services.
This visual guide breaks down important metrics across four categories: Patient-Centered Metrics, Care Efficiency Metrics, Quality of Life Metrics, and Staff Metrics. Each section is designed to help healthcare professionals monitor and improve care delivery for patients facing serious illnesses. Understand how to implement these metrics in your palliative care practices for better outcomes and higher satisfaction levels.
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfSachin Sharma
This content provides an overview of preventive pediatrics. It defines preventive pediatrics as preventing disease and promoting children's physical, mental, and social well-being to achieve positive health. It discusses antenatal, postnatal, and social preventive pediatrics. It also covers various child health programs like immunization, breastfeeding, ICDS, and the roles of organizations like WHO, UNICEF, and nurses in preventive pediatrics.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
Health Education on prevention of hypertensionRadhika kulvi
Hypertension is a chronic condition of concern due to its role in the causation of coronary heart diseases. Hypertension is a worldwide epidemic and important risk factor for coronary artery disease, stroke and renal diseases. Blood pressure is the force exerted by the blood against the walls of the blood vessels and is sufficient to maintain tissue perfusion during activity and rest. Hypertension is sustained elevation of BP. In adults, HTN exists when systolic blood pressure is equal to or greater than 140mmHg or diastolic BP is equal to or greater than 90mmHg. The
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
2. Change to CPR/CCR
• Emphasis on:
– Starting compressions sooner
– Minimally interrupted compressions
– High performance CPR
3. Change to CPR/CCR
• No more 30:2 for Adults
– Pediatric – follow standard AHA CPR
• Instead:
– Cycles of 2 minutes uninterrupted compressions
– Check rhythm every 2 minutes
– Ventilate every 10th compression on the upstroke
• Do not interrupt compressions to ventilate
• Don’t overventilate – will cause gastric distention
• Consider using pediatric BVM
4.
5. CCR
• CCR still for first 8 minutes in presumed
cardiac etiology
– NOT for respiratory arrest, opiate OD, pediatrics,
or trauma
– Passive ventilation with OPA and NRB will usually
be used at first
– May transition to active ventilations once
sufficient personnel/resources are present
• This could be immediate, at 2 minutes, 8 minutes or
any point in between
6. No More “20 Minute Then Transport”
• Resuscitation performed on scene until ROSC or termination of
efforts EXCEPT for ‘special circumstances’
– “Special Circumstances” not well defined in protocol but think “can
the hospital do something to fix this that I can’t?” Ex:
• Hypothermia (central rewarming)
• Pulmonary embolism (lytics, ECMO, IR)
• Pregnancy with potentially viable fetus (perimortem c-section)
• Etc.
• Still AT LEAST 20 minutes ALS resuscitation before considering
termination
– Definitively manage airway prior to termination
– Should continue resuscitation if ROSC is likely such as in cases with:
• Witnessed arrest and early CPR
• Reversible cause
• etCO2 >15mmHg
• Persistent vfib/v-tach
• Etc.
7. Changes to ALS Arrest Management
• Antiarrhythmics now “per AHA ACLS guidelines”
• Medics should use etCO2 with BLS and ALS airway to
assess CPR quality and for signs of ROSC
• Bicarb indications (now 2 mEQ/kg IV)
– Suspected excited delerium
• New indication – that patient you were restraining who isn’t
breathing any more…
– Suspected pre-existing metabolic acidosis
– Known tricyclic OD (tox protocol also includes other Na
channel blockers such as cocaine and Benadryl)
– Should insert an advanced airway before bicarb
• Bicarb works by creating CO2
• May be harmful in a ‘closed system’ (i.e. ineffective ventilations)
8. Team Focused CPR
• Send a rescuer in ahead (with just gloves) to start
compressions
• Pre-defined roles and positions
– Different ways to set this up depending on resources
– Goal is efficiency
• The example described in the protocols follows
but may be adapted
– Protocol example assumes at least 4 ALS providers on
scene
– Strive for multiple ALS providers to fill roles
– ALS provider may need to fill multiple roles
11. Team Focused CPR
Compressor #1 and #2
• One on each side of chest
– May be new to most but can really help
– One starts compressions, the other applies
AED/Defibrilator
– Seamlessly alternate (every one minute mid-cycle
or every 2 minutes) to avoid fatigue
– ‘Hover’ hands during interruptions
– Pre-charge manual defib before analysis
– Assist with mask seal/ventilation when not
compressing
12. Team Focused CPR
Airway and Vascular
• Airway (at patient’s head)
– Inserts OPA, applies NRB
– 2 handed BVM mask seal – off-cycle compressor
or airway assistant squeezes bag
– Inserts advanced airway after 8 minutes
– May have 2nd “airway assistant”
• Vascular/Meds
– Just like the name implies
– Stays out of the ‘CPR triangle’
13. Team Focused CPR
Team Leader
• Most of us use this already but
– Clear job responsibilities help to maintain consistency
and high performance in the resuscitation
• Job assignment:
– Coaches CPR metrics
– Calls for compressor change every minute
– Calls for rhythm analysis every 2 minutes and
immediate shock if indicated
– Monitor CPR quality (depth, rate, interruption) and
use of metronome (100-120 bpm)
– May have to do other tasks (e.g. Airway or Vascular)
14. Team Focused CPR
Code Commander
• Ideally highest level provider
– May have to do double duty as team leader
• Coordinates patient treatment decisions
– Can interface with OLMC without disruption to
resuscitation
• Communicates with family/loved ones
– Essential, especially if termination will be
considered
• Completes CPR Checklist (new to most)
15. CPR Checklist Example
Code Commander and pit crew roles defined
Chest compression interruptions minimized
Compressors rotated minimum every 2 minutes
Metronome set between 100-120 bpm
AED/Defib applied
O2 flowing and attached to NRB/BVM
EtCO2 waveform present
IV/IO access established
Possible causes considered
Gastric insufflation limited and gastric decompression
considered
Family present and ongoing communication provided
17. Mechanical CPR
• 2015 AHA Evidence review:
– 2 large RCTs compared the use of LUCAS against
manual compressions for patients with OHCA
– Together enrolled 7060 patients
– Neither demonstrated a benefit for mechanical CPR
over manual CPR with respect to early (4-hour) and
late (1- and 6-month) survival
– The PARAMEDIC study demonstrated a negative
association between mechanical chest compressions
and survival with good neurologic outcome (Cerebral
Performance Category 1–2) at 3 months as compared
with manual compressions
18. Mechanical CPR
• 2015 AHA Recommendation:
– “The evidence does not demonstrate a benefit with the use of
mechanical piston devices for chest compressions versus manual
chest compressions in patients with cardiac arrest.”
– “Mechanical piston devices may be considered in specific
settings where the delivery of high-quality manual compressions
may be challenging or dangerous provided that rescuers strictly
limit interruptions in CPR during deployment and removal of the
devices.” Ex:
• Limited rescuers available
• Prolonged CPR
• During hypothermic cardiac arrest
• In a moving ambulance
• In the angiography suite
• During preparation for extracorporeal CPR [ECPR]),
19. Mechanical CPR
• Hartford Hospital Expectations if using
mechanical CPR:
– Apply only after first 8 minutes manual CPR
– At least yearly training and competency evaluation
– MUST be able to reliably apply with less than 5
second (at most 10 second) interruptions in CPR
• Time this in training; Team leader watch for this in real
life
– Discontinue and revert to manual CPR if device or
application problems occur