2 3 4 5 Assignments -#1 Distinguish between the following genetic term.docx
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2 3 4 5 Assignments \#1 Distinguish between the following genetic terms: A. Gene and allele. B. Homozygous and heterozygous. C. Genotype and phenotype. D. Dominant and recessive. 1. A man with red-green colour blindness is married to a girl with normal colour vision. What is the probability that his children will be colour blind? 2. A boy has Duchenne muscular dystrophy. His maternal uncle had died of muscular dystrophy at the age of 21 years. What is the probability that this child's sibs will be affected? Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant, autosomal recessive or X-linked dominant and X -linked recessive inheritance. (Note that a pedigree may be compatible with more than one type of inheritance.) a. b. c. a. b. c. Assignments \#4 Examine the pedigree from a family with a genetic disease and ansv the questions below: a. Does this pedigree indicate autosomal dominant, recessive or sex-link type of inheritance? Give reasons for your choice. b. Assuming that B and b are the normal and mutant alleles respectively what would be the genotypes of the individuals: II.I, II.2 and III.3? c. Individual II.3 requested genetic counselling. What is the probability that her child would be affected. Explain why. Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. Is it carried on an autosome or a sex chromosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected). In comparing these 11 SNP results, how long a haplotype block would you expect to find around the critical gene? How might you detect it? .
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Please give an explaination fir those quesions! 2 3 4 5 1- Aman with r.docx
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1. Aman with red.geen colour blindness is marned to a girl with normal colwir vision. What is the probaliliny that his childron will be coluur blind? 2. A boy has Dachenne muscular dyatrophy. His malemal uncle had died of museular dystrophy at the age of 21 years. What is the prohatility that this chilfs sibs will be affected? Assignments \#3 rocosive or S -kinked dominant and X -linked recesive inheritance. (Nole that a potigrte may be coempable with muve thas ane type of inheritance.) Assignnents \#4 Examine the pedieree frum a funily with a ernetic disease and anvv the questiens below: a. Does this pedigree isdicate autosonal deuninant, teoessive of set-link type of inheritance? Give reasons for your choice. b. Assuaning that B and b are the normal and mataut alleies respectively what would be the enenotypes of the individuals :II.1, 11 2 and III .3? c. Individual II. 3 requested genctic counselling. What is the probubility that her child woald be affected. Fxplain why. Assignments \#5 Susan's grandfather was deaf, and passed down a hercditary form of deafhess within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant of recessive?? B. Is it carried on an autosome of a sex cluomosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected) In comparing these 11 SNP result, how long a haplotype block would you expect to find around the critical \#ene? How might you deleet it? Assignments \#1 Distinguish between the following genetic terms: A. Gene and allele. B. Homozygous and heterozygous. C. Genotype and phenotype. D. Dominant and recessive. 1. A man with red-green colour blindness is married to a girl with normal colour vision. What is the probability that his children will be colour blind? 2. A boy has Duchenne muscular dystrophy. His maternal uncle had died of muscular dystrophy at the age of 21 years. What is the probability that this child's sibs will be affected? Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant, autosomal recessive or X -linked dominant and X -linked recessive inheritance. (Note that a pedigree may be compatible with more than one type of inheritance.) a. b. c. a. b. c. Assignments \#4 Examine the pedigree from a family with a genetic disease and ansv the questions below: a. Does this pedigree indicate autosomal dominant, recessive or sex-link type of inheritance? Give reasons for your choice. b. Assuming that B and b are the normal and mutant alleles respectively what would be the genotypes of the individuals: II.I, II.2 and III.3 ? c. Individual II. 3 requested genetic counselling. What is the probability that her child would be affected. Explain why. Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. I.
5- The pedigree below wis from a tare kidney disease- a) What is the m.docx
5. The pedigree below wis from a tare kidney disease: a) What is the most likely mode of inheritance for this disease? Explain your reasons. b) If person \#1 and \#2 have offspring, what is the probability that the first child will have kidney disease? c) If person HI:and H2 have 2 offspring, what is the probability that neither will have kidney disease? 6. For each pedigree below, indicate the most likely mode of inheritance (i.e,, autosomal or sexlinked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits. 7. For the pedigree below determine the most likely mode of inheritance (i.e,, autosomal or sex-linked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits
.
5- The pedigree below wis from a tare kidney disease- a) What is the m.docx
5. The pedigree below wis from a tare kidney disease: a) What is the most likely mode of inheritance for this disease? Explain your reasons. b) If person \#1 and \#2 have offspring, what is the probability that the first child will have kidney disease? c) If person HI:and H2 have 2 offspring, what is the probability that neither will have kidney disease? 6. For each pedigree below, indicate the most likely mode of inheritance (i.e,, autosomal or sexlinked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits. 7. For the pedigree below determine the most likely mode of inheritance (i.e,, autosomal or sex-linked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits
.
Please- answers all my question is for genetic class 3- Describe the.docx
Please, answers all my question is for genetic class
3. Describe the pattern of inheritance shown in the pedigree below, giving evidence to support your answer. Give the genotypes for individuals II-2, II-4 and II-2. Include a legend for the symbols used. (10 marks) Describe the pattern of inheritance shown in the pedigree below, giving evidence to support your answer. Give the genotypes for individuals II-4, II-7 and III-7. Include a legend for the symbols used. ( 10 marks) 5. A type of hemophilia is due to an X-linked recessive allele. An affected man whose phenotype has been successfully managed now has children with a woman who is a carrier. Providing a legend for your, answer the following questions: a. What are the genotypes of the mother and father? (1 mark) b. What are the probabilities that i. a child will be affected with hemophilia. ii. a child is a carrier. iii. their daughter is a carrier. iv. their male fetus will be affected. (4 marks) 6. Genes for two different recessive disorders are linked on the X chromosome; they are 26 map units apart. A woman is a carrier for both disorder A and disorder B , with the alleles for these genes in cis. Her husband has normal alleles for both of these genes. The woman is pregnant with their first son. What is the probability (in percent) this son is affected with both disorders? Explain, showing the proportions and types of the woman's gametes and identifying them as parental or recombinant. (5 marks) 7. In certain human matings of albino and black-haired parents, the offspring are always blackhaired. When these black-haired offspring of the different families mate with each other (non-consanguineously) and their children are pooled to get significant data, these are the children's phenotypic proportions: 9 black-haired children 3 brown-haired children 4 albino children a. How many genes are involved in this trait? b. How many alleles of each gene are there? c. What type of gene interaction is occurring for this trait? Describe it. d. What are the genotypes of the initial albino and black-haired parents? Provide a legend. e. What are the genotypes of their offspring (all black-haired)? f. What are the genotypes and the specific proportions of the albino children in the third generation? g. What are the genotypes of the brown-haired children? 8. Which type of chromosomal aneuploidy typically has less severe effects on an individual: sex chromosome aneuploidy or autosomal aneuploidy? Explain why. (4 marks) 9. An organism has six chromosomes in its somatic cells. Determine the number of gametes with different chromosome compositions that this organism can potentially create. Explain your answer, including the genetic basis for your calculation. Ignore the allelic variation created by crossing over. ( 4 marks) 10. Compare the inheritance and transmission of Xlinked genes with that of mitochondrial genes. (4 marks) 11. A woman has a normal number of fingers and toes. She has many relatives with ex.
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Please give an explaination fir those quesions! 2 3 4 5 1- Aman with r.docx
Please give an explaination fir those quesions!
2
3
4
5
1. Aman with red.geen colour blindness is marned to a girl with normal colwir vision. What is the probaliliny that his childron will be coluur blind? 2. A boy has Dachenne muscular dyatrophy. His malemal uncle had died of museular dystrophy at the age of 21 years. What is the prohatility that this chilfs sibs will be affected? Assignments \#3 rocosive or S -kinked dominant and X -linked recesive inheritance. (Nole that a potigrte may be coempable with muve thas ane type of inheritance.) Assignnents \#4 Examine the pedieree frum a funily with a ernetic disease and anvv the questiens below: a. Does this pedigree isdicate autosonal deuninant, teoessive of set-link type of inheritance? Give reasons for your choice. b. Assuaning that B and b are the normal and mataut alleies respectively what would be the enenotypes of the individuals :II.1, 11 2 and III .3? c. Individual II. 3 requested genctic counselling. What is the probubility that her child woald be affected. Fxplain why. Assignments \#5 Susan's grandfather was deaf, and passed down a hercditary form of deafhess within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant of recessive?? B. Is it carried on an autosome of a sex cluomosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected) In comparing these 11 SNP result, how long a haplotype block would you expect to find around the critical \#ene? How might you deleet it? Assignments \#1 Distinguish between the following genetic terms: A. Gene and allele. B. Homozygous and heterozygous. C. Genotype and phenotype. D. Dominant and recessive. 1. A man with red-green colour blindness is married to a girl with normal colour vision. What is the probability that his children will be colour blind? 2. A boy has Duchenne muscular dystrophy. His maternal uncle had died of muscular dystrophy at the age of 21 years. What is the probability that this child's sibs will be affected? Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant, autosomal recessive or X -linked dominant and X -linked recessive inheritance. (Note that a pedigree may be compatible with more than one type of inheritance.) a. b. c. a. b. c. Assignments \#4 Examine the pedigree from a family with a genetic disease and ansv the questions below: a. Does this pedigree indicate autosomal dominant, recessive or sex-link type of inheritance? Give reasons for your choice. b. Assuming that B and b are the normal and mutant alleles respectively what would be the genotypes of the individuals: II.I, II.2 and III.3 ? c. Individual II. 3 requested genetic counselling. What is the probability that her child would be affected. Explain why. Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. I.
5- The pedigree below wis from a tare kidney disease- a) What is the m.docx
5. The pedigree below wis from a tare kidney disease: a) What is the most likely mode of inheritance for this disease? Explain your reasons. b) If person \#1 and \#2 have offspring, what is the probability that the first child will have kidney disease? c) If person HI:and H2 have 2 offspring, what is the probability that neither will have kidney disease? 6. For each pedigree below, indicate the most likely mode of inheritance (i.e,, autosomal or sexlinked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits. 7. For the pedigree below determine the most likely mode of inheritance (i.e,, autosomal or sex-linked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits
.
5- The pedigree below wis from a tare kidney disease- a) What is the m.docx
5. The pedigree below wis from a tare kidney disease: a) What is the most likely mode of inheritance for this disease? Explain your reasons. b) If person \#1 and \#2 have offspring, what is the probability that the first child will have kidney disease? c) If person HI:and H2 have 2 offspring, what is the probability that neither will have kidney disease? 6. For each pedigree below, indicate the most likely mode of inheritance (i.e,, autosomal or sexlinked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits. 7. For the pedigree below determine the most likely mode of inheritance (i.e,, autosomal or sex-linked, dominant or recessive) and the probability of the individuals indicated by the question marks being affected. Assume that the traits are rare in the general population and that the pedigrees show complete penetrance for the traits
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Please- answers all my question is for genetic class 3- Describe the.docx
Please, answers all my question is for genetic class
3. Describe the pattern of inheritance shown in the pedigree below, giving evidence to support your answer. Give the genotypes for individuals II-2, II-4 and II-2. Include a legend for the symbols used. (10 marks) Describe the pattern of inheritance shown in the pedigree below, giving evidence to support your answer. Give the genotypes for individuals II-4, II-7 and III-7. Include a legend for the symbols used. ( 10 marks) 5. A type of hemophilia is due to an X-linked recessive allele. An affected man whose phenotype has been successfully managed now has children with a woman who is a carrier. Providing a legend for your, answer the following questions: a. What are the genotypes of the mother and father? (1 mark) b. What are the probabilities that i. a child will be affected with hemophilia. ii. a child is a carrier. iii. their daughter is a carrier. iv. their male fetus will be affected. (4 marks) 6. Genes for two different recessive disorders are linked on the X chromosome; they are 26 map units apart. A woman is a carrier for both disorder A and disorder B , with the alleles for these genes in cis. Her husband has normal alleles for both of these genes. The woman is pregnant with their first son. What is the probability (in percent) this son is affected with both disorders? Explain, showing the proportions and types of the woman's gametes and identifying them as parental or recombinant. (5 marks) 7. In certain human matings of albino and black-haired parents, the offspring are always blackhaired. When these black-haired offspring of the different families mate with each other (non-consanguineously) and their children are pooled to get significant data, these are the children's phenotypic proportions: 9 black-haired children 3 brown-haired children 4 albino children a. How many genes are involved in this trait? b. How many alleles of each gene are there? c. What type of gene interaction is occurring for this trait? Describe it. d. What are the genotypes of the initial albino and black-haired parents? Provide a legend. e. What are the genotypes of their offspring (all black-haired)? f. What are the genotypes and the specific proportions of the albino children in the third generation? g. What are the genotypes of the brown-haired children? 8. Which type of chromosomal aneuploidy typically has less severe effects on an individual: sex chromosome aneuploidy or autosomal aneuploidy? Explain why. (4 marks) 9. An organism has six chromosomes in its somatic cells. Determine the number of gametes with different chromosome compositions that this organism can potentially create. Explain your answer, including the genetic basis for your calculation. Ignore the allelic variation created by crossing over. ( 4 marks) 10. Compare the inheritance and transmission of Xlinked genes with that of mitochondrial genes. (4 marks) 11. A woman has a normal number of fingers and toes. She has many relatives with ex.
A wild-type chromosome has the following segments A B C middot D E F.pdf
A wild-type chromosome has the following segments: A B C middot D E F G H I An individual
is heterozygous for the following chromosome mutation: A B C middot D H I How would the
mutated and wild-type chromosomes pair in prophase I of meiosis? D E F G H of the wild-type
chromosome will form a deletion loop. E F G of the wild-type chromosome will form a deletion
loop. D E F G H of the wild-type chromosome will form an Inversion loop. E F G of the wild-
type chromosome will form an inversion loop. Red-green color blindness is a human x-linked
recessive disorder. A young man with a 47, XXY karyotype (Klinefelter syndrome) is color
Wind. His 46, XY brother also is color blind. Both parents have normal color vision. Where did
the no disjunction that gave rise to the young man with Klinefelter syndrome take place? Assume
that no crossing over took place In prophase I of meiosis. Mother - meiosis I Mother - meiosis II
Father - meiosis I Father - meiosis II Both parents Functional epidermal lies bull nose (JEB) Is a
severe skin disorder that results in blisters over the entire body. The disorder is caused by
autosomal recessive mutations at any one of three loci that help to encode lamina 5, a major
component In the dermal-epidermal basement membrane. Leena Pulicine and colleagues
described a male newborn who was born with JEB and died at 2 months of age (L. Pulkkinen et
al. 1997. American Journal of Human Genetics 61:611-619); the child had healthy unrelated
parents. Chromosome analysis revealed that the infant had 46 normal-appearing chromosomes.
Analysis of DNA showed that his mother was heterozygous for a JEB-causing allele at the
LAMB3 locus, which is on chromosome 1. The father had two normal alleles at this locus. DNA
fingerprinting demonstrated that the male assumed to be the father had, In fact, conceived the
child. Assuming that no new mutations occurred in this family, what might best explain the
presence of an autosomal recessive disease in the child when the mother is heterozygous and the
father Is homozygous normal? The infant inherited both copies of chromosome 1 from the
mother, which is an example of unit parental disomic. The infant is monatomic for chromosome
1, which he received from his mother but did not receive a chromosome 1 from his father.
Epitasis masked the disease phenotype in the father, but complementation of the parental alleles
gave rise to a child with functional epidermal lies bull nose. The infant has tiresome 1, where he
inherited two recessive alleles from his mother. A translocation between chromosome 1 and
chromosome 22 generated a recessive phenotype. Plasmid DNA, like bacterial DNA: is circular.
is single stranded. comes in homologous pairs. All of the above. None of the above.
Solution
10. Answer is B. EFG of the wild type will form a deletion loop. Because EFG in one
chromosome has no matching pair in other chromosome. So EFG loop will be formed and it will
be removed.
13. Answer is A. Plasmid DNA like bacte.
1. In a given plant, the yellow seed color allele (Y) is dominant to .pdf
1. In a given plant, the yellow seed color allele (Y) is dominant to green seed color (y). Give the
genotypic and phenotypic ratios for the following crosses? a. homozygous yellow x green b.
heterozygous yellow x green c. heterozygous yellow x heterozygous yellow d. green x green 2. If
two animals heterozygous for a single pair of genes are mated and have 276 offspring, how many
would be expected to have the dominant genotype? 3. Two long-winged fies are mated. The
offspring included 90 with long wings and 32 with short wings. Which phenotype is recessive?
4. A blood test reveals that a couple both have the sickle-cell trat. What is the probability of their
producing a child with sickle-cell anemia? 5. A blood type A woman has a type B child. She
accuses a type O man of being the father. Knowing genetics you are asked to give an opinion; do
so. 6. Assume that human eye color is controlled by a single pair of alleles. A blue-eyed man,
both of whose parents were bom brown-eyed, marries a brown-eyed woman whose father was
blue-eyed and whose mother was brown-eyed. They have a blue-eyed child. Which are the
genotypes of all individuals mentioned? 7. A red fruit, tall tomato plant RrTt, is crossed with a
yellow-fruited dwarf plant ritt. What genotypes and phenotypes would be expected in the
offispring? 8. What genotype and phenotype would be expected in the offspring if the cross in
the previous problem had been RrTt x RrTt ?.
2.Cross a heterozygous tall and round seed pea plant with anothe.docx
2.
Cross a heterozygous tall and round seed pea plant with another heterozygous tall, round seed plant.
3.
Cross a pea plant that is heterozygous for purple flowers and homozygous dominant for yellow seeds with a plant that is heterozygous for purple flowers and homozygous recessive for green seeds.
Cross a plant that is heterozygous for round seeds and homozygous recessive for white flowers with a plant that is homozygous recessive for wrinkled seeds and heterozygous for purple flowers.
Blood Type
5.
What are the possible genotypes for each blood type?
Phenotype
Genotype
Type A
Type B
Type
AB
Type O
Juan has blood type A (I
A
I
A
), his wife Lucia has blood type B (I
B
i). What are the possible genotypes of their children?
Answer:
A child has genotype of ii. If the child’s mother has a genotype of I
A
i, which blood types COULD represent the father?
Dad Mom Baby
____ ____ ____ _____ ____ ____
Dad’s possible Genotypes
Dad’s possible Phenotypes
If a man with blood type O marries a woman with Type A, what would be the possible phenotypes of the offspring?
9.
What are the possible genotypes of children born to a man that has the genotype I
A
i and a woman that has the genotype I
A
I
B
?
10.
What blood types can donate blood to (list all):
a.
A person with type A blood?
b.
A person with type O blood?
c.
A person with type AB blood?
SEX LINKED TRAITS:
11.
Rickets is a condition in which the bones become soft. Children with rickets develop bone deformities. A lack of vitamin D, calcium, and phosphorus in the diet usually cause this condition. One form of rickets, called vitamin D-resistant rickets, is caused by the recessive trait on the X chromosome
. A mother who is heterozygous for rickets marries a man who HAS rickets.
Normal=
Rickets=
Mom=
Dad=
a.
What chance do they have of having a
daughter
with rickets
?
b.
What chance do they have of having a
daughter
that is a carrier of rickets
?
c.
What chance do they have of having a
son
who isnormal
?
d.
What chance do they have of having a
child
with rickets
?
Baldness is a sex-linked trait. Sam wanted to know if he would be bald when he grew up. Therefore, Sam decided to find out how much of a chance he had of becoming bald. Through research, he found out that
his
mother is a carrier for the baldness trait and that his father has a normal gene for hair.
a.
What chance does Sam have of being
bald
when he gets older?
b.
What chance would of having
a
daughter
who will be bald
?
c.
What chance would of having
a
daughter
who is a carrier of the baldness trait
?
In humans colorblindness is a sex-linked, recessive gene. Having normal vision is dominant. A
woman who is heterozygous
for colorblindness marries a
man who is normal
.
.
Using Probability in Genetics 1- Let's say you roll a dice (standard s.pdf
Using Probability in Genetics 1. Let's say you roll a dice (standard sides 1-6), Show work here:
what is the probability it will land on a 2 or a 5 ? To solve this, will you use the addition rule or
multiplication rule? Why? 2. The genotype of a particular plant is Show work here: AaBbCcDd .
If this plant was self-crossed, what is the probability that the offspring would have the following
genotypes: a) AaBBCCDD b) aaBBecdd c) AaBbCcDd (Hint: don't do a tetrahybrid cross, do
monohybrid crosses for each gene then use the multiplication rule.) 3. Approximately 4000 years
ago, a small Show work here: number of people settled in areas of Finland and became separated
from the rest of the population. These people reproduced, but due to the low number of people, it
caused a loss of genetic diversity in the subsequent offspring, which caused many disorders to
arise. These disorders are collectively known as Finnish heritage diseases. This event was so
significant that even today, one in five Finnish people carry at least one gene related to a Finnish
heritage disease. A man and a woman, both of Finnish heritage are aware of this, so they see a
genetic counselor. They are interested in having a child, but fear they may pass on a disease.
They have their DNA analyzed and it comes back that they are both carriers for the recessive
disease known as megaloblastic anemia, a type of anemia common in Finnish descent.
Thankfully, if they have an affected child, it is treatable. a) What is the probability that, if they
have a child,. it will have megaloblastic anemia? b) Let's say they decide to have three children
total. What is the probability that all three children would have the disease? c) What is the
probability that, if they have three children, none of them will have the disease?.
1 Tom and Sharons second child has cystic fibrosis a rece.pdf
1. Tom and Sharons second child has cystic fibrosis (a recessive condition). Sharon is pregnant.
What
are the chances her new baby will have cystic fibrosis? What are the chances her oldest child,
who is
normal, is a carrier?
2. Tom is type O and Sharon is type AB. What blood genotypes and phenotypes could their
children be?
3. Below is a pedigree of myopia (near sightedness) in which individuals afflicted by this condition
are
shaded; normal individuals are not shaded. The gene that produces myopia is
a. Dominant c. Sex Linked b. Recessive d. Polygenic
For the following individuals in the pedigree, tell if they are (a) homozygous, (b) heterozygous, or
(c) unable to be classified because of lack of data
Individual 1 _____ Individual 4 _____
Individual 2 _____ Individual 5 _____
Individual 3 _____ Individual 6 _____.
Answer the following questions1. Given the following matings, w
Answer the following questions:
1. Given the following matings, what are the predicted genotypes and genotypic ratios of the offspring?
a) Aa X aa
b) Aa X Aa
c) AA X Aa
2. Wet ear wax (W) is dominant over dry ear wax (w)
a) A 3:1 phenotypic ratio of F1 progeny indicates that the parents are of what genotype?
b) A 1:1 phenotypic ratio of F1 progeny indicates that the parents are of what genotype?
3. A woman is heterozygous for two genes. How many different types of gametes can she produce, and in what proportions?
4. The following diagram shows a hypothetical diploid cell:
The recessing allele for albinism is represented by a, and d represents the recessive allele for deafness. The normal alleles are represented by A and D, respectively.
a) According to the principle of segregation, what is segregating in these cells?
b) According to Mendel’s principle of independent assortment, what is independently assorting in these cells?
c) How many chromatids are in this cell?
d) Write a genotype of the individual from which this cell was taken.
e) What is the phenotype of this individual?
f) What stage of cell division (mitosis or meiosis) is represented by this cell?
g) After meiosis is complete, how many chromatids and chromosomes will be present in one of the four progeny cells?
5. Draw the following simple pedigree. A man and a woman have three children: a daughter, then two sons. The daughter marries and has monozygotic twin girls (identical twins). The youngest son in generation II is affected with albinism. (Use proper pedigree symbols; draw, scan and add picture to document; do not submit picture independently).
6. A man with blood type A and a women with blood type B have three children. A daughter with AB and two sons, one with type B and one with type O blood. What are the genotypes of the parents?
...
Linked inheritance
Breaking down Biology into simpler bits is the most effective way to learn hence this presentation aims to simplify the concept of 'Linked Inheritance' which makes understanding Inheritance better.
Assignment DetailsOpen DateApr 2, 2018 1205 AMGradedYes.docx
Assignment Details
Open Date
Apr 2, 2018 12:05 AM
Graded?
Yes
Points Possible
100.0
Resubmissions Allowed?
No
Attachments checked for originality?
Yes
Top of Form
Assignment Instructions
Develop a chart or diagram that will illustrate how prenatal development is influenced by environmental or genetic factors. Creativity is strongly suggested. There is no requirement for APA format in this assignment. There is no requirement of references for this assignment.
Supporting Materials
· 308 Assignment 2. Rubric.doc (50 KB)
Bottom of Form
Nature and Nurture: Genetic and Environmental Foundations of Child Development
Child development is impacted by both genetic or inherited factors and environmental factors. Genetic factors are inherited from both parents at the time of conception, but can be the result of different types of gene interactions. Environmental factors impact different ways families function and children develop. Environmental factors include the ecological systems that may alter family function, socio-economic status and cultural values and public policy.
TOPICS COVERED WILL INCLUDE:
· Genetics
· Family functioning from an ecological systems perspective
· The impact of socioeconomic status
· Cultural values and public policies
“Toddler hopscotch” by Ilya Haykinson is licensed under CC BY 2.0
The Influence of Alleles
In the argument over nature versus nurture in child development, nature is determined by genes passed down from parent to child during conception. Both parents pass genetic traits to their offspring, but different offspring may acquire different traits from each parent. Why do some children in one family have similar characteristics or appearances and yet other children in the same family look very different? The answer lies in the interaction of genes inherited from the mother and father.
Genes and alleles influence the inheritance of traits, through dominant–recessive inheritance, incomplete dominance, X-linked inheritance, genomic imprinting, mutation, and polygenic inheritance. In order to understand genetic inheritance, you need to understand the basics of how genes work, and how they work together with one another.
Fundamental Definitions
Understanding the basic structures and elements of genetics is essential to recognize how various traits are inherited, from appearance to intelligence.
GENE
The basic building block of the study of genetics is the gene; a gene is a single unit of genetic information.
CHROMOSOME
A chromosome is a threadlike strand of DNA encoded with a large number of genes. Humans receive 23 chromosomes from each parent, for a total of 46 chromosomes.
ALLELE
An allele is one of a pair of genes that appear at a particular location on a particular chromosome and control the same characteristics in the individual. Humans have two alleles, one from each parent, at each genetic locus, or position, on a chromosome.
GENOTYPE
The entire genetic makeup of an individual is called the genotype. The geno ...
Congenital Bone & Joint Diseases
Congenital Bone & Joint DiseasesDepartment of Orthopaedics & Trauma, Faculty of Medicine / King AbdulAziz University
Sex Linkage-Unique Heritage
This presentation intends to explore the sex-linked characters along with some fatal diseases of human beings, their cause, consequences and other issues.
3- (22 pts) Tennessee Walking Horses and Clydesdales are breeds of hor.docx
3. (22 pts) Tennessee Walking Horses and Clydesdales are breeds of horses that have the sabino white color pattern. The gene for sabino in Tennessee Walkers is on a different locus from that for Clydesdales. Both are dominant genes, and each breed is homozygous recessive for the other breed's sabino gene. The Tennessee Walker is heterozygous for their breed's sabino gene (homozygous dominant individuals are completely white), while Clydesdales are homozygous for their breed's sabino gene. A. (2 pts) If SB1 represents the dominant allele for sabino in Tennessee Walkers and B the dominant allele for sabino in Clydesdales, what is the genotype of each breed if they are sabino? B. (10 pts) Assume the cross between dihybrids sabino individuals from these breeds (heterozygous for all loci). What are the genotypic and phenotypic ratios in the foals? C. ( 2 pts) How many unique gametes can the sire from 3 B produce? D. (2 pts) How many unique zygotes can be produced from the mating described in 3B E. (2 pts) What is the probability of a sabino foal in the progeny of this mating? F. (2 pts) Assuming that during the foaling season were born 1000 colts, how many are sabino?
.
28) Multiple Answer- Which statements are TRUE concerning the thalassa.docx
28) Multiple Answer: Which statements are TRUE concerning the thalassaemia major disorder? Please select all that are correct.
Can result in enlarged spleens.
Individuals are predisposed to developmental delays.
Is most common in Chinese populations.
Is aggravated by high fetal hemoglobin production.
Is associated with increased risk of bone defects.
.
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Similar to 2 3 4 5 Assignments -#1 Distinguish between the following genetic term.docx
A wild-type chromosome has the following segments A B C middot D E F.pdf
A wild-type chromosome has the following segments: A B C middot D E F G H I An individual
is heterozygous for the following chromosome mutation: A B C middot D H I How would the
mutated and wild-type chromosomes pair in prophase I of meiosis? D E F G H of the wild-type
chromosome will form a deletion loop. E F G of the wild-type chromosome will form a deletion
loop. D E F G H of the wild-type chromosome will form an Inversion loop. E F G of the wild-
type chromosome will form an inversion loop. Red-green color blindness is a human x-linked
recessive disorder. A young man with a 47, XXY karyotype (Klinefelter syndrome) is color
Wind. His 46, XY brother also is color blind. Both parents have normal color vision. Where did
the no disjunction that gave rise to the young man with Klinefelter syndrome take place? Assume
that no crossing over took place In prophase I of meiosis. Mother - meiosis I Mother - meiosis II
Father - meiosis I Father - meiosis II Both parents Functional epidermal lies bull nose (JEB) Is a
severe skin disorder that results in blisters over the entire body. The disorder is caused by
autosomal recessive mutations at any one of three loci that help to encode lamina 5, a major
component In the dermal-epidermal basement membrane. Leena Pulicine and colleagues
described a male newborn who was born with JEB and died at 2 months of age (L. Pulkkinen et
al. 1997. American Journal of Human Genetics 61:611-619); the child had healthy unrelated
parents. Chromosome analysis revealed that the infant had 46 normal-appearing chromosomes.
Analysis of DNA showed that his mother was heterozygous for a JEB-causing allele at the
LAMB3 locus, which is on chromosome 1. The father had two normal alleles at this locus. DNA
fingerprinting demonstrated that the male assumed to be the father had, In fact, conceived the
child. Assuming that no new mutations occurred in this family, what might best explain the
presence of an autosomal recessive disease in the child when the mother is heterozygous and the
father Is homozygous normal? The infant inherited both copies of chromosome 1 from the
mother, which is an example of unit parental disomic. The infant is monatomic for chromosome
1, which he received from his mother but did not receive a chromosome 1 from his father.
Epitasis masked the disease phenotype in the father, but complementation of the parental alleles
gave rise to a child with functional epidermal lies bull nose. The infant has tiresome 1, where he
inherited two recessive alleles from his mother. A translocation between chromosome 1 and
chromosome 22 generated a recessive phenotype. Plasmid DNA, like bacterial DNA: is circular.
is single stranded. comes in homologous pairs. All of the above. None of the above.
Solution
10. Answer is B. EFG of the wild type will form a deletion loop. Because EFG in one
chromosome has no matching pair in other chromosome. So EFG loop will be formed and it will
be removed.
13. Answer is A. Plasmid DNA like bacte.
1. In a given plant, the yellow seed color allele (Y) is dominant to .pdf
1. In a given plant, the yellow seed color allele (Y) is dominant to green seed color (y). Give the
genotypic and phenotypic ratios for the following crosses? a. homozygous yellow x green b.
heterozygous yellow x green c. heterozygous yellow x heterozygous yellow d. green x green 2. If
two animals heterozygous for a single pair of genes are mated and have 276 offspring, how many
would be expected to have the dominant genotype? 3. Two long-winged fies are mated. The
offspring included 90 with long wings and 32 with short wings. Which phenotype is recessive?
4. A blood test reveals that a couple both have the sickle-cell trat. What is the probability of their
producing a child with sickle-cell anemia? 5. A blood type A woman has a type B child. She
accuses a type O man of being the father. Knowing genetics you are asked to give an opinion; do
so. 6. Assume that human eye color is controlled by a single pair of alleles. A blue-eyed man,
both of whose parents were bom brown-eyed, marries a brown-eyed woman whose father was
blue-eyed and whose mother was brown-eyed. They have a blue-eyed child. Which are the
genotypes of all individuals mentioned? 7. A red fruit, tall tomato plant RrTt, is crossed with a
yellow-fruited dwarf plant ritt. What genotypes and phenotypes would be expected in the
offispring? 8. What genotype and phenotype would be expected in the offspring if the cross in
the previous problem had been RrTt x RrTt ?.
2.Cross a heterozygous tall and round seed pea plant with anothe.docx
2.
Cross a heterozygous tall and round seed pea plant with another heterozygous tall, round seed plant.
3.
Cross a pea plant that is heterozygous for purple flowers and homozygous dominant for yellow seeds with a plant that is heterozygous for purple flowers and homozygous recessive for green seeds.
Cross a plant that is heterozygous for round seeds and homozygous recessive for white flowers with a plant that is homozygous recessive for wrinkled seeds and heterozygous for purple flowers.
Blood Type
5.
What are the possible genotypes for each blood type?
Phenotype
Genotype
Type A
Type B
Type
AB
Type O
Juan has blood type A (I
A
I
A
), his wife Lucia has blood type B (I
B
i). What are the possible genotypes of their children?
Answer:
A child has genotype of ii. If the child’s mother has a genotype of I
A
i, which blood types COULD represent the father?
Dad Mom Baby
____ ____ ____ _____ ____ ____
Dad’s possible Genotypes
Dad’s possible Phenotypes
If a man with blood type O marries a woman with Type A, what would be the possible phenotypes of the offspring?
9.
What are the possible genotypes of children born to a man that has the genotype I
A
i and a woman that has the genotype I
A
I
B
?
10.
What blood types can donate blood to (list all):
a.
A person with type A blood?
b.
A person with type O blood?
c.
A person with type AB blood?
SEX LINKED TRAITS:
11.
Rickets is a condition in which the bones become soft. Children with rickets develop bone deformities. A lack of vitamin D, calcium, and phosphorus in the diet usually cause this condition. One form of rickets, called vitamin D-resistant rickets, is caused by the recessive trait on the X chromosome
. A mother who is heterozygous for rickets marries a man who HAS rickets.
Normal=
Rickets=
Mom=
Dad=
a.
What chance do they have of having a
daughter
with rickets
?
b.
What chance do they have of having a
daughter
that is a carrier of rickets
?
c.
What chance do they have of having a
son
who isnormal
?
d.
What chance do they have of having a
child
with rickets
?
Baldness is a sex-linked trait. Sam wanted to know if he would be bald when he grew up. Therefore, Sam decided to find out how much of a chance he had of becoming bald. Through research, he found out that
his
mother is a carrier for the baldness trait and that his father has a normal gene for hair.
a.
What chance does Sam have of being
bald
when he gets older?
b.
What chance would of having
a
daughter
who will be bald
?
c.
What chance would of having
a
daughter
who is a carrier of the baldness trait
?
In humans colorblindness is a sex-linked, recessive gene. Having normal vision is dominant. A
woman who is heterozygous
for colorblindness marries a
man who is normal
.
.
Using Probability in Genetics 1- Let's say you roll a dice (standard s.pdf
Using Probability in Genetics 1. Let's say you roll a dice (standard sides 1-6), Show work here:
what is the probability it will land on a 2 or a 5 ? To solve this, will you use the addition rule or
multiplication rule? Why? 2. The genotype of a particular plant is Show work here: AaBbCcDd .
If this plant was self-crossed, what is the probability that the offspring would have the following
genotypes: a) AaBBCCDD b) aaBBecdd c) AaBbCcDd (Hint: don't do a tetrahybrid cross, do
monohybrid crosses for each gene then use the multiplication rule.) 3. Approximately 4000 years
ago, a small Show work here: number of people settled in areas of Finland and became separated
from the rest of the population. These people reproduced, but due to the low number of people, it
caused a loss of genetic diversity in the subsequent offspring, which caused many disorders to
arise. These disorders are collectively known as Finnish heritage diseases. This event was so
significant that even today, one in five Finnish people carry at least one gene related to a Finnish
heritage disease. A man and a woman, both of Finnish heritage are aware of this, so they see a
genetic counselor. They are interested in having a child, but fear they may pass on a disease.
They have their DNA analyzed and it comes back that they are both carriers for the recessive
disease known as megaloblastic anemia, a type of anemia common in Finnish descent.
Thankfully, if they have an affected child, it is treatable. a) What is the probability that, if they
have a child,. it will have megaloblastic anemia? b) Let's say they decide to have three children
total. What is the probability that all three children would have the disease? c) What is the
probability that, if they have three children, none of them will have the disease?.
1 Tom and Sharons second child has cystic fibrosis a rece.pdf
1. Tom and Sharons second child has cystic fibrosis (a recessive condition). Sharon is pregnant.
What
are the chances her new baby will have cystic fibrosis? What are the chances her oldest child,
who is
normal, is a carrier?
2. Tom is type O and Sharon is type AB. What blood genotypes and phenotypes could their
children be?
3. Below is a pedigree of myopia (near sightedness) in which individuals afflicted by this condition
are
shaded; normal individuals are not shaded. The gene that produces myopia is
a. Dominant c. Sex Linked b. Recessive d. Polygenic
For the following individuals in the pedigree, tell if they are (a) homozygous, (b) heterozygous, or
(c) unable to be classified because of lack of data
Individual 1 _____ Individual 4 _____
Individual 2 _____ Individual 5 _____
Individual 3 _____ Individual 6 _____.
Answer the following questions1. Given the following matings, w
Answer the following questions:
1. Given the following matings, what are the predicted genotypes and genotypic ratios of the offspring?
a) Aa X aa
b) Aa X Aa
c) AA X Aa
2. Wet ear wax (W) is dominant over dry ear wax (w)
a) A 3:1 phenotypic ratio of F1 progeny indicates that the parents are of what genotype?
b) A 1:1 phenotypic ratio of F1 progeny indicates that the parents are of what genotype?
3. A woman is heterozygous for two genes. How many different types of gametes can she produce, and in what proportions?
4. The following diagram shows a hypothetical diploid cell:
The recessing allele for albinism is represented by a, and d represents the recessive allele for deafness. The normal alleles are represented by A and D, respectively.
a) According to the principle of segregation, what is segregating in these cells?
b) According to Mendel’s principle of independent assortment, what is independently assorting in these cells?
c) How many chromatids are in this cell?
d) Write a genotype of the individual from which this cell was taken.
e) What is the phenotype of this individual?
f) What stage of cell division (mitosis or meiosis) is represented by this cell?
g) After meiosis is complete, how many chromatids and chromosomes will be present in one of the four progeny cells?
5. Draw the following simple pedigree. A man and a woman have three children: a daughter, then two sons. The daughter marries and has monozygotic twin girls (identical twins). The youngest son in generation II is affected with albinism. (Use proper pedigree symbols; draw, scan and add picture to document; do not submit picture independently).
6. A man with blood type A and a women with blood type B have three children. A daughter with AB and two sons, one with type B and one with type O blood. What are the genotypes of the parents?
...
Linked inheritance
Breaking down Biology into simpler bits is the most effective way to learn hence this presentation aims to simplify the concept of 'Linked Inheritance' which makes understanding Inheritance better.
Assignment DetailsOpen DateApr 2, 2018 1205 AMGradedYes.docx
Assignment Details
Open Date
Apr 2, 2018 12:05 AM
Graded?
Yes
Points Possible
100.0
Resubmissions Allowed?
No
Attachments checked for originality?
Yes
Top of Form
Assignment Instructions
Develop a chart or diagram that will illustrate how prenatal development is influenced by environmental or genetic factors. Creativity is strongly suggested. There is no requirement for APA format in this assignment. There is no requirement of references for this assignment.
Supporting Materials
· 308 Assignment 2. Rubric.doc (50 KB)
Bottom of Form
Nature and Nurture: Genetic and Environmental Foundations of Child Development
Child development is impacted by both genetic or inherited factors and environmental factors. Genetic factors are inherited from both parents at the time of conception, but can be the result of different types of gene interactions. Environmental factors impact different ways families function and children develop. Environmental factors include the ecological systems that may alter family function, socio-economic status and cultural values and public policy.
TOPICS COVERED WILL INCLUDE:
· Genetics
· Family functioning from an ecological systems perspective
· The impact of socioeconomic status
· Cultural values and public policies
“Toddler hopscotch” by Ilya Haykinson is licensed under CC BY 2.0
The Influence of Alleles
In the argument over nature versus nurture in child development, nature is determined by genes passed down from parent to child during conception. Both parents pass genetic traits to their offspring, but different offspring may acquire different traits from each parent. Why do some children in one family have similar characteristics or appearances and yet other children in the same family look very different? The answer lies in the interaction of genes inherited from the mother and father.
Genes and alleles influence the inheritance of traits, through dominant–recessive inheritance, incomplete dominance, X-linked inheritance, genomic imprinting, mutation, and polygenic inheritance. In order to understand genetic inheritance, you need to understand the basics of how genes work, and how they work together with one another.
Fundamental Definitions
Understanding the basic structures and elements of genetics is essential to recognize how various traits are inherited, from appearance to intelligence.
GENE
The basic building block of the study of genetics is the gene; a gene is a single unit of genetic information.
CHROMOSOME
A chromosome is a threadlike strand of DNA encoded with a large number of genes. Humans receive 23 chromosomes from each parent, for a total of 46 chromosomes.
ALLELE
An allele is one of a pair of genes that appear at a particular location on a particular chromosome and control the same characteristics in the individual. Humans have two alleles, one from each parent, at each genetic locus, or position, on a chromosome.
GENOTYPE
The entire genetic makeup of an individual is called the genotype. The geno ...
Congenital Bone & Joint Diseases
Congenital Bone & Joint DiseasesDepartment of Orthopaedics & Trauma, Faculty of Medicine / King AbdulAziz University
Sex Linkage-Unique Heritage
This presentation intends to explore the sex-linked characters along with some fatal diseases of human beings, their cause, consequences and other issues.
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1 Tom and Sharons second child has cystic fibrosis a rece.pdf
Answer the following questions1. Given the following matings, w
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C.minor's imperitive
D.age of indececy
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