Please give an explaination fir those quesions! 2 3 4 5 1. Aman with red.geen colour blindness is marned to a girl with normal colwir vision. What is the probaliliny that his childron will be coluur blind? 2. A boy has Dachenne muscular dyatrophy. His malemal uncle had died of museular dystrophy at the age of 21 years. What is the prohatility that this chilfs sibs will be affected? Assignments \#3 rocosive or S -kinked dominant and X -linked recesive inheritance. (Nole that a potigrte may be coempable with muve thas ane type of inheritance.) Assignnents \#4 Examine the pedieree frum a funily with a ernetic disease and anvv the questiens below: a. Does this pedigree isdicate autosonal deuninant, teoessive of set-link type of inheritance? Give reasons for your choice. b. Assuaning that B and b are the normal and mataut alleies respectively what would be the enenotypes of the individuals :II.1, 11 2 and III .3? c. Individual II. 3 requested genctic counselling. What is the probubility that her child woald be affected. Fxplain why. Assignments \#5 Susan's grandfather was deaf, and passed down a hercditary form of deafhess within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant of recessive?? B. Is it carried on an autosome of a sex cluomosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected) In comparing these 11 SNP result, how long a haplotype block would you expect to find around the critical \#ene? How might you deleet it? Assignments \#1 Distinguish between the following genetic terms: A. Gene and allele. B. Homozygous and heterozygous. C. Genotype and phenotype. D. Dominant and recessive. 1. A man with red-green colour blindness is married to a girl with normal colour vision. What is the probability that his children will be colour blind? 2. A boy has Duchenne muscular dystrophy. His maternal uncle had died of muscular dystrophy at the age of 21 years. What is the probability that this child's sibs will be affected? Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant, autosomal recessive or X -linked dominant and X -linked recessive inheritance. (Note that a pedigree may be compatible with more than one type of inheritance.) a. b. c. a. b. c. Assignments \#4 Examine the pedigree from a family with a genetic disease and ansv the questions below: a. Does this pedigree indicate autosomal dominant, recessive or sex-link type of inheritance? Give reasons for your choice. b. Assuming that B and b are the normal and mutant alleles respectively what would be the genotypes of the individuals: II.I, II.2 and III.3 ? c. Individual II. 3 requested genetic counselling. What is the probability that her child would be affected. Explain why. Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. I.

1. Please give an explaination fir those quesions!
2
3
4
5
1. Aman with red.geen colour blindness is marned to a girl with normal colwir vision. What is
the probaliliny that his childron will be coluur blind? 2. A boy has Dachenne muscular
dyatrophy. His malemal uncle had died of museular dystrophy at the age of 21 years. What is the
prohatility that this chilfs sibs will be affected? Assignments #3 rocosive or S -kinked dominant
and X -linked recesive inheritance. (Nole that a potigrte may be coempable with muve thas ane
type of inheritance.) Assignnents #4 Examine the pedieree frum a funily with a ernetic disease
and anvv the questiens below: a. Does this pedigree isdicate autosonal deuninant, teoessive of
set-link type of inheritance? Give reasons for your choice. b. Assuaning that B and b are the
normal and mataut alleies respectively what would be the enenotypes of the individuals :II.1, 11
2 and III .3? c. Individual II. 3 requested genctic counselling. What is the probubility that her
child woald be affected. Fxplain why. Assignments #5 Susan's grandfather was deaf, and passed
down a hercditary form of deafhess within Susan's family as shown in Figure. A. Is this mutation
most likely to be dominant of recessive?? B. Is it carried on an autosome of a sex cluomosome?
Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and
7 unaffected) In comparing these 11 SNP result, how long a haplotype block would you expect
to find around the critical #ene? How might you deleet it? Assignments #1 Distinguish between
the following genetic terms: A. Gene and allele. B. Homozygous and heterozygous. C. Genotype
and phenotype. D. Dominant and recessive. 1. A man with red-green colour blindness is married
to a girl with normal colour vision. What is the probability that his children will be colour blind?
2. A boy has Duchenne muscular dystrophy. His maternal uncle had died of muscular dystrophy
at the age of 21 years. What is the probability that this child's sibs will be affected? Explain,
giving reasons, whether the following pedigrees are compatible with autosomal dominant,
autosomal recessive or X -linked dominant and X -linked recessive inheritance. (Note that a
pedigree may be compatible with more than one type of inheritance.) a. b. c. a. b. c. Assignments
#4 Examine the pedigree from a family with a genetic disease and ansv the questions below: a.
Does this pedigree indicate autosomal dominant, recessive or sex-link type of inheritance? Give
reasons for your choice. b. Assuming that B and b are the normal and mutant alleles respectively
what would be the genotypes of the individuals: II.I, II.2 and III.3 ? c. Individual II. 3 requested
genetic counselling. What is the probability that her child would be affected. Explain why.
Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's
family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. Is it
carried on an autosome or a sex chromosome? Why? C. A complete SNP analysis has been done
for all of the 11 grandchildren (4 affected, and 7 unaffected). In comparing these 11 SNP results,
how long a haplotype block would you expect to find around the critical gene? How might you
detect it?