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Please, answers all my question is for genetic class
3. Describe the pattern of inheritance shown in the pedigree below, giving evidence to support
your answer. Give the genotypes for individuals II-2, II-4 and II-2. Include a legend for the
symbols used. (10 marks) Describe the pattern of inheritance shown in the pedigree below,
giving evidence to support your answer. Give the genotypes for individuals II-4, II-7 and III-7.
Include a legend for the symbols used. ( 10 marks) 5. A type of hemophilia is due to an X-linked
recessive allele. An affected man whose phenotype has been successfully managed now has
children with a woman who is a carrier. Providing a legend for your, answer the following
questions: a. What are the genotypes of the mother and father? (1 mark) b. What are the
probabilities that i. a child will be affected with hemophilia. ii. a child is a carrier. iii. their
daughter is a carrier. iv. their male fetus will be affected. (4 marks) 6. Genes for two different
recessive disorders are linked on the X chromosome; they are 26 map units apart. A woman is a
carrier for both disorder A and disorder B , with the alleles for these genes in cis. Her husband
has normal alleles for both of these genes. The woman is pregnant with their first son. What is
the probability (in percent) this son is affected with both disorders? Explain, showing the
proportions and types of the woman's gametes and identifying them as parental or recombinant.
(5 marks) 7. In certain human matings of albino and black-haired parents, the offspring are
always blackhaired. When these black-haired offspring of the different families mate with each
other (non-consanguineously) and their children are pooled to get significant data, these are the
children's phenotypic proportions: 9 black-haired children 3 brown-haired children 4 albino
children a. How many genes are involved in this trait? b. How many alleles of each gene are
there? c. What type of gene interaction is occurring for this trait? Describe it. d. What are the
genotypes of the initial albino and black-haired parents? Provide a legend. e. What are the
genotypes of their offspring (all black-haired)? f. What are the genotypes and the specific
proportions of the albino children in the third generation? g. What are the genotypes of the
brown-haired children? 8. Which type of chromosomal aneuploidy typically has less severe
effects on an individual: sex chromosome aneuploidy or autosomal aneuploidy? Explain why. (4
marks) 9. An organism has six chromosomes in its somatic cells. Determine the number of
gametes with different chromosome compositions that this organism can potentially create.
Explain your answer, including the genetic basis for your calculation. Ignore the allelic variation
created by crossing over. ( 4 marks) 10. Compare the inheritance and transmission of Xlinked
genes with that of mitochondrial genes. (4 marks) 11. A woman has a normal number of fingers
and toes. She has many relatives with extra fingers and toes: her father, grandfather, brother and
three cousins. Her husband has the normal number of digits, and none of his relatives have extra
fingers and toes. This couple has a child with six fingers on each hand, another child with six
toes on one foot, and one child with no extra fingers or toes. A genetic counselor has told the
couple this trait, known as polydactyly, is autosomal dominant. What other information could be
given to the couple to explain the unusual inheritance pattern of this trait? (4 marks) 12. Explain
how a mitochondrial disease may not be evident until adulthood. ( 3 marks) 13. List five
characteristics of mitochondrial genetic information that differ from nuclear genetic information.
(5 marks) 14. Compare independent assortment occurring when genes are on different
chromosomes to independent assortment occurring when two genes are on opposite ends of a
chromosome. Use the example of an individual with the genotype AaBb, with cis parental allele
combinations, indicating and explaining the types and proportions of gametes made. (5 marks)
Please- answers all my question is for  genetic class 3- Describe the.docx

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  • 1. Please, answers all my question is for genetic class 3. Describe the pattern of inheritance shown in the pedigree below, giving evidence to support your answer. Give the genotypes for individuals II-2, II-4 and II-2. Include a legend for the symbols used. (10 marks) Describe the pattern of inheritance shown in the pedigree below, giving evidence to support your answer. Give the genotypes for individuals II-4, II-7 and III-7. Include a legend for the symbols used. ( 10 marks) 5. A type of hemophilia is due to an X-linked recessive allele. An affected man whose phenotype has been successfully managed now has children with a woman who is a carrier. Providing a legend for your, answer the following questions: a. What are the genotypes of the mother and father? (1 mark) b. What are the probabilities that i. a child will be affected with hemophilia. ii. a child is a carrier. iii. their daughter is a carrier. iv. their male fetus will be affected. (4 marks) 6. Genes for two different recessive disorders are linked on the X chromosome; they are 26 map units apart. A woman is a carrier for both disorder A and disorder B , with the alleles for these genes in cis. Her husband has normal alleles for both of these genes. The woman is pregnant with their first son. What is the probability (in percent) this son is affected with both disorders? Explain, showing the proportions and types of the woman's gametes and identifying them as parental or recombinant. (5 marks) 7. In certain human matings of albino and black-haired parents, the offspring are always blackhaired. When these black-haired offspring of the different families mate with each other (non-consanguineously) and their children are pooled to get significant data, these are the children's phenotypic proportions: 9 black-haired children 3 brown-haired children 4 albino children a. How many genes are involved in this trait? b. How many alleles of each gene are there? c. What type of gene interaction is occurring for this trait? Describe it. d. What are the genotypes of the initial albino and black-haired parents? Provide a legend. e. What are the genotypes of their offspring (all black-haired)? f. What are the genotypes and the specific proportions of the albino children in the third generation? g. What are the genotypes of the brown-haired children? 8. Which type of chromosomal aneuploidy typically has less severe effects on an individual: sex chromosome aneuploidy or autosomal aneuploidy? Explain why. (4 marks) 9. An organism has six chromosomes in its somatic cells. Determine the number of gametes with different chromosome compositions that this organism can potentially create. Explain your answer, including the genetic basis for your calculation. Ignore the allelic variation created by crossing over. ( 4 marks) 10. Compare the inheritance and transmission of Xlinked genes with that of mitochondrial genes. (4 marks) 11. A woman has a normal number of fingers and toes. She has many relatives with extra fingers and toes: her father, grandfather, brother and three cousins. Her husband has the normal number of digits, and none of his relatives have extra fingers and toes. This couple has a child with six fingers on each hand, another child with six toes on one foot, and one child with no extra fingers or toes. A genetic counselor has told the couple this trait, known as polydactyly, is autosomal dominant. What other information could be given to the couple to explain the unusual inheritance pattern of this trait? (4 marks) 12. Explain how a mitochondrial disease may not be evident until adulthood. ( 3 marks) 13. List five characteristics of mitochondrial genetic information that differ from nuclear genetic information. (5 marks) 14. Compare independent assortment occurring when genes are on different chromosomes to independent assortment occurring when two genes are on opposite ends of a chromosome. Use the example of an individual with the genotype AaBb, with cis parental allele combinations, indicating and explaining the types and proportions of gametes made. (5 marks)