Secondary brain injury occurs after the initial primary brain injury and can develop hours or days later due to complications from the primary mechanism of injury. Neurocritical care aims to prevent secondary brain injuries by maintaining adequate oxygenation and circulation to the brain and managing factors like intracranial pressure and hypotension that can exacerbate the initial injury. However, the best time to save neurons is before they reach the neurocritical care unit since once there, the damage may already be done.