The Wnt signaling pathway is an important developmental pathway that is activated upon binding of Wnt ligands to Frizzled and LRP receptors. This prevents degradation of beta-catenin, allowing it to enter the nucleus and activate target genes in conjunction with TCF transcription factors. Key components of the pathway include Wnt ligands, Frizzled and LRP receptors, cytoplasmic proteins like Dsh and Axin, and nuclear proteins like beta-catenin and TCF. Mutations in various components of this pathway can lead to developmental defects or diseases like cancer.