Nightside clouds and disequilibrium chemistry on the hot Jupiter WASP-43b
The Human Body: An Orientation
1. C H A P T E R 1 – T H E H U M A N B O D Y : A N
O R I E N T A T I O N
ANATOMY & PHYSIOLOGY
2. A N O V E R V I E W O F A N A T O M Y A N D
P H Y S I O L O G Y
CHAPTER 1
3. Let’s start with the basics
anatomy: the study of the structure and shape of the
body and its parts and their relationships to one another
gross anatomy: the study of large body structures (human body)
microscopic anatomy: the study of body structures too small to be
seen with the naked eye (cells and tissues)
physiology: the study of how the body and its parts work
or function
4. They are ALWAYS related
The parts of the body form a well-organized unit
You want to view the body in terms of structure and
function
Cardiovascular system
5. W H Y M U S T W E U S E L E V E L S O F
O R G A N I Z A T I O N ?
LEVELS OF ORGANIZATION
6. The basics
Each level contains progressively larger structures
The structure in each level is composed of structures
from the preceding level
7. Level 1 – Chemical Level
Smallest level of organization
From atoms up to molecules
atoms: the building blocks of all matter
ex. H, H2O
8. Level 2 – Cellular Level
cells: the smallest unit of all living things
Ex. neuron
9. Level 3 – Tissue Level
tissue: consist of groups similar cells that have a
common function
4 basic types (epithelial, connective, muscular,
neural)
ex. neural tissue
10. Level 4 – Organ Level
organ: structure composed of two or more tissues
types that performs a specific function
at this level, extremely complex functions become
possible
ex. brain
11. Level 5 – Organ System Level
organ system: a group of organs that work together
to accomplish a common purpose
ex. CNS
12. Level 6 – Organismal Level
Organismal Level
organism: an individual living thing composed of
multiple organ systems working together
Humans use 11 organ systems
14. 11 Organ Systems
We will examine each system in more detail later in
the year
Look at both the structures involved and how each of
these structures function both independently and
together
Take note how the organ systems are interrelated
15. Integumentary System
structure: skin (external covering of the body)
function:
1. waterproofs the body
2. cushions and protects deeper tissues from injury
3. excretes salts and urea during perspiration
4. helps regulate body temperature
16. Skeletal System
structure: bones, cartilages,
ligaments, joints
function:
1. supports the body
2. provides a framework for
skeletal muscles
3. protects some organs
4. performs hematopoiesis
hematopoiesis: formation of
blood cells
17. Muscular System
structure: skeletal muscles
function: to contract and to
allow movement
viewed as the “machines” of
the body
allows for locomotion,
maintains posture,
produces heat, etc.
18. Nervous System
structure: brain, spinal cord, nerves, sensory receptors
(body’s fast-acting control system)
function:
1. respond to external stimuli
2. respond to internal stimuli
assesses information and responds by activating the
appropriate body effectors (muscles or glands)
19. Endocrine System
structure: pituitary, thyroid, parathyroids, adrenals,
thymus, and pineal glands, pancreas, ovaries/testis
function:
1. controls body activities (slower than the nervous
system)
2. produce and release hormones
20. Cardiovascular System
structure: heart and blood vessels
function:
1. carries oxygen, nutrients,
hormones, and other substances to
and from tissue cells where
exchanges are made
2. WBCs help protect the body from
foreign invaders (bacteria, toxins,
tumor cells)
21. Respiratory System
structure: nasal passages,
pharynx, larynx (vocal cords),
trachea, bronchi and lungs,
function:
1. keeps body constantly supplied
with oxygen
2. removes carbon dioxide from
the body
thin walls of the air sacs allows
gases to be transported to and
from the lungs
22. Lymphatic System
structure: lymphatic vessels,
lymph nodes, spleen, tonsils
function: 1. returns fluid
leaked from the blood back to
the blood vessels
2. help cleanse the blood and
house cells involved in
immunity
complements the
cardiovascular system
23. Digestive System
structure: (mouth -> anus)
oral cavity (mouth), esophagus, stomach, small and large
intestines, rectum, anus
function:
1. breakdown food
2. deliver products to the blood for dispersal to the body
cells
3. reclaim water (large intestines)
liver is a digestive organ because it produces bile, which
helps break down fats
pancreas delivers digestive enzymes to the small
intestines, functionally a digestive organ
25. Urinary System (Excretory System)
structure: kidneys, ureters,
bladder, urethra
function:
1. removes Nitrogen-containing
wastes from the blood in the form
of urine
2. helps maintain salt and water
balance (electrolyte)
3. regulates the acid-base balance
of the blood
26. Reproductive System
structure:
in males: testes, scrotum, penis, accessory glands,
and duct system
in females: ovaries, uterine tubes, uterus, vagina
function: to produce offspring
27. WHAT THINGS MUST HAPPEN IN
INDIVIDUAL ORGAN SYSTEMS AND
BETWEEN MULTIPLE ORGAN
SYSTEMS TO ALLOW THE HUMAN
BODY TO FUNCTION?
NECESSARY LIFE
FUNCTIONS
28. The basic idea
all organisms must use and maintain necessary life
functions
organ systems are interdependent
it is important to establish which organ systems are
most directly related to each life function
29. What must happen:
1. Maintain Boundaries
2. Movement
3. Responsiveness
4. Digestion
5. Metabolism
6. Excretion
7. Reproduction
8. Growth
30. Maintaining Boundaries
Maintaining Boundaries
every living organism needs to maintain boundaries to
keep “insides” distinct from “outsides”
every individual cell has a membrane (most semi- or
selectively permeable) (microscopic anatomy)
the body is enclosed by the Integumentary system
(gross anatomy)
protects internal organs from drying out
protects internal organs from bacteria
protects body from the damaging effects of heat, sunlight,
chemical substances, and the external environment
31. Movement
movement: all activities promoted by the muscular
system
muscular system provides the muscles
skeletal system provides the bones the muscles pull
on as they work
movement also occurs when substances are
propelled through the internal organs of the
cardiovascular, digestive and urinary systems
32. Responsiveness
responsiveness: (also called irritability) is the ability
to sense changes in the environment and react to
them
the nervous system is the most responsible for
responsiveness
however, all body cells are irritable to some extent.
33. Digestion
digestion: the process of breaking down ingested
food into simple molecules that can be absorbed into
the blood
in the complex body this is performed by the
digestive system
34. Metabolism
metabolism: a broad term that refers to all
chemical reactions that occur within body cells
includes:
breaking down complex molecules into simpler ones
using Oxygen and nutrients to produce molecules of ATP
(adenosine triphosphate, the energy-rich molecules that
power cell activities)
depends on the respiratory, digestive, and
cardiovascular systems
mainly regulated by hormones secreted by the
glands on the endocrine system
35. Excretion
excretion: the process of removing excreta (wastes)
from the body
nonuseful substances produced during digestion and
metabolism must be removed
several organ systems participate in excretion,
including the digestive and urinary systems
36. Reproduction
reproduction: the production of offspring
can occur at both the cellular and organismal levels
ex. mitosis in cells, human reproduction
task of the reproductive system, regulated precisely
by the hormones of the endocrine system
37. Growth
growth: an increase in size, usually accomplished by
an increase in the number of cells
for growth to occur, cell-constructing activities must
occur at a faster rate than cell-destroying ones
38. W H A T A R E T H E B A S I C S U B S T A N C E S
N E C E S S A R Y F O R H U M A N S U R V I V A L ?
SURVIVAL NEEDS
39. Survival Needs
several factors necessary for maintaining life
nutrients, Oxygen, water, appropriate temperature
and atmospheric pressure
must be present in appropriate amounts; too much
or too little may be equally harmful
40. Survival Needs
1. Nutrients
body takes in through food
contain the chemicals used for energy and cell building
proteins, carbohydrates, etc
2. Oxygen
the chemical reactions that release energy from foods
require Oxygen
approximately 20% of the air we breathe is Oxygen
(20.95%)
41. Survival Needs
3. water
60-80 % body weight, 65-75% in muscle, only 10% in fat
50-60% in most people, women have a lower percentage
due to higher body fat
single most abundant chemical substance in the body
provides the fluid base for body secretions and excretions
(secretion is an active process/particle movement,
excretion is a passive process/waste removal)
chiefly ingested from foods and liquids
lost by evaporation and body excretions
42. Survival Needs
4. body temperature
must be maintained around 37°C or 98.6°F
as temperature drops, metabolic reactions slow until
they stop
as temperature rises, metabolic reactions speed up
and can proceed too rapidly
at either extreme, death will occur
most body heat is generated by the activity of skeletal
muscles
43. Survival Needs
5. atmospheric pressure
atmospheric pressure: the force exerted on the
surface of the body by the weight of the air
breathing and the exchange of oxygen and carbon
dioxide in the lungs depend on appropriate
atmospheric pressure
45. Homeostasis
homeostasis: a state of body equilibrium or stable
internal environment of the body
literally means “unchanging”
(homeo = the same, stasis = standing still)
dynamic state of equilibrium
ex. blood pressure, waste accumulation, body
temperature
46. Homeostasis
communication is key, and is mainly controlled by
the nervous and endocrine systems
nerves
bloodborne hormones
The factor being regulated by homeostasis is the
variable
47. Homeostasis
all homeostatic control mechanisms have at least
three components:
1. A receptor
2. A control center
3. An effector
48. A receptor
a receptor that responds to environmental changes
some type of sensor that monitors and responds to
change
stimulus: the change (pl. stimuli)
sends information(input) to the second element (the
control center) along the afferent pathway
the afferent pathway approaches the control center
49. A control center
a control center that assesses changes
determines the level at which a variable is to be
maintained
analyzes the information it receives
determines the appropriate course of action or response
50. The effector
provides the means for the control center’s response
(output) to the stimulus
information flows from control center to the effector
along the efferent pathway
efferent information exits from the control center
the results of the response feedback to influence the
stimulus
either depresses (negative feedback) or enhances
(positive feedback)
51. Negative Feedback Systems
Negative feedback mechanisms: the
net effect of the response to the
stimulus is to shut off the original
stimulus or reduce its intensity
most homeostatic control
mechanisms
ex. Home thermostat
hypothalamus in the body
also includes heart rate, blood
pressure, breathing rate, blood
nutrient levels
52. Positive Feedback Systems
Positive feedback mechanisms: tend to increase the
original disturbance (stimulus) and to push the
variable farther from its original value
rare in the body
events that occur explosively
ex. Blood clotting, birth
53. Homeostatic Imbalance
Homeostasis is so important that most diseases can
be regarded as homeostatic imbalances
as age increases, organ function decreases, and the
risk of disease/homeostatic imbalance as increases