3. Description
• It was invented in 1879 by a scientist name
Franz von Soxhlet.
• This technique is also known as Hot
continuous extraction process.
• soxhlet extraction is a technique of continuous
extraction of a Component from solid
granules.
• Typically, a soxhlet extraction is only required
where the desired compound has limited
solubility in a solvent,and the impurity is
insoluble in that solvent.
4. Components
It basically consist of three parts:-
Part-A)Distillation Flask/round bottom Flask
-it hold solvent and extract
Part –B)Extraction chamber
-thimble ( crude drug such as black pepper)
Part-C)Condenser
-form vapour to liquid
5. Principle of soxhlet extraction
• the basic principles involve in this process are :- evaporation, condensation
and percolation.
• Percolation:-It is a continuous Flow of the solvent through to the Bed of
crude drug Material to get the extrate.
• In this process,hot and fresh Solvent percolated Over the sample of crude
drug containing lipid .
• Then,when percolater fill with condensed solvent Above the siphon,it return
back to RBF.
• Process repeated it desirable extract is obtained.
7. Advantages and disadvantage
Advantages Disadvantage
Continuous process Long time process(>24hrs)
Complete extraction possible Poor extraction of polar lipids
Environmental friendly Large volume of solvents required
Isolation of limited soluble fat
and lipid is possible
Solubility problem of drug may
arises.
8. Applications
It is most useful apparatus for solid-liquid extraction in
various fields such as
-pharmaceutics
-environments and also
- food stuffs
Fat extraction from
-prefried and fried meat
- fish and
-bakery products
Oli extraction from
-olive seeds
-oleaginous seeds
