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PTSD:
Post-traumatic Stress
Disorder
Hannah McCormack
Abnormal Psychology
Dr. Rosenthal
A month later…
Flashbacks and
nightmares
about the car
crash
Easily aroused
by loud noises
Avoiding
neighborhood
where she
experienced the
crash
Avoiding
driving in her car
Hasn’t been
going to
McDonalds
because one was
on the road
Erwin Rd.
Sounds like you
might be suffering
from PTSD. Let me
tell you more about
this disorder
Re-
experiencing
Flashback
Intrusive
thoughts &
memories
Nightmares
Hyper
Arousal
Heightened
awareness of
triggers
Easily
startled
Irritable
Insomnia
Avoidance
Avoid similar
situations
Emotional
numbing
Tendency to
withdraw
Etiology
A Traumatic Event
Generalized Biological
Vulnerabilities
Generalized Psychological
Vulnerabilities
Environmental
Factors
Biological Vulnerabilities
Genetics
Serotonin transporter gene
•Two short alleles
Damage to the
hippocampus
HPA axis dysfunction
Psychological Vulnerabilities
Avoidance based
coping strategies
Lack of positive
coping strategies
•Problem solving
External locus of
control
Minimal education
Family instability
Lack of a strong network
for social support
Maltreated as a child
Environmental Factors
I now better
understand what
caused me to
develop PTSD, but
what maintains the
disorder?
Maintenance
Onset of PTSD
Directly after
Trauma
Acute stress
disorder
Not PTSD time will
often heal
Acute if symptoms
last less than 3
months
Better prognosis
Chronic if persists 3
months or mother
Delayed onset
More guarded
prognosis
At least 6 months
Reason for delayed
onset is unknown
Traumatic event
Intense fear and
anxiety
surrounding cars
Avoid using your
car on highway
You temporarily
suppress your
anxiety and fear
Thoughts becomes
more intrusive and
common
Significant
dysfunction and
distress
Bike to the doctors
office
This sounds
serious, is there
anyway to treat this
disorder?
Treatment
E
X
P
O
S
U
R
E
Traumatic event
car crash
Intense fear and
anxiety
surrounding cars
Avoid using your
car on highway
Expose patient to
the fear
Overcome fears
Reduce avoidance
and withdrawal
Allow you to drive
your car
Coping strategies
+ CS, control
Cognitive
Processing
Therapy
Repeatedly talking
about the problem
with the patient
Correct
assumptions
about the
trauma
•Self blame
•Feelings of guilt
Shift in
cognition 
shift in
behavior
Medication
Cognitive
Processing
Therapy &
Prolonged
Exposure
Medication
Other
Treatments
Social Support
Eye Movement
Desensitization
and
Reprocessing
Virtual Reality
Wow, What an
informative answer.
Looks like my life will
be able to go back to
normal after all.
I’m so happy I
can drive to the
beach again
Bisson, J. I. (2007). Post-traumatic stress disorder. Occupational Medicine,
57(6), 399-403.
Bremner, J., Randall, P., Vermetten, E., Staib, L., Bronen, R. A., Mazure, C.,
et al. (1997). Magnetic resonance imaging-based measurement of
hippocampal volume in posttraumatic stress disorder related to
childhood physical and sexual abuse-a preliminary report.
Biological Psychiatry, 41(1), 23-32.
Breslau, N., Davis, G. C., & Andreski, P. (1995). Risk factors for PTSD-
related traumatic events: A prospective analysis. The American
Journal of Psychiatry, 152(4), 529-535.
References
Foa, E. B., Keane, T. M., Friedman, M. J., & Cohen, J. A. (Eds.). (2009).
Effective treatments for PTSD. New York, NY: The Guilford Press.
Keane, T. M., Marshall, A. D., & Taft, C. T. (2006). Posttraumatic stress
disorder: Etiology, epidemiology, and treatment outcome. Annual
Review of Clinical Psychology, 2, 161-197.
King, D. W., King, L. A., & Foy, D. W. (1996). Prewar factors in combat-
related posttraumatic stress disorder: Structural equation modeling
with a national sample of female and male vietnam veterans. Journal
of Consulting and Clinical Psychology, 64(3), 520-531.
Lee, H. -., Lee, M. -., Kang, R. -., Kim, H., Kim, S. -., Kee, B. -., et al. (2005).
Influence of the serotonin transporter promoter gene polymorphism
on susceptibility to posttraumatic stress disorder. Depression and
Anxiety, 21(3), 135--139.
Lyons, M. J., Goldberg, J., Eisen, S. A., True, W., Tsuang, M. T., Meyer, J. M.,
et al. (1993). Do gnenes influence exposure to trauma? A twin study
of combat. American Journal of Medical Genetics, 48(1), 22-27.
Tarrier, N., Sommerfield, C., & Pilgrim, H. (199). Relatives; espressed
emotion (EE) and PTSD treatment outcome. Psychological Medicine,
29, 801-808.
Van Etten, M. L., & Taylor, S. (1998). Comparative efficacy of treatments for
post-traumatic stress disorder: A meta-analysis. Clinical Psychology
and Psychotherapy, 5(3), 126-144.
Widows, M. R., Jacobsen, P. B., & Fields, K. K.,. (2000). Relation of
psychological vulnerability facotrs to posttraumatic stress disorders
symptomatology in bone marrow transplant recipients.
Psychosomatic Medicine, 62(6), 873-882.

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Ptsd mccormack course project

  • 2.
  • 3. A month later… Flashbacks and nightmares about the car crash Easily aroused by loud noises Avoiding neighborhood where she experienced the crash Avoiding driving in her car Hasn’t been going to McDonalds because one was on the road
  • 5. Sounds like you might be suffering from PTSD. Let me tell you more about this disorder
  • 6.
  • 9. A Traumatic Event Generalized Biological Vulnerabilities Generalized Psychological Vulnerabilities Environmental Factors
  • 10. Biological Vulnerabilities Genetics Serotonin transporter gene •Two short alleles Damage to the hippocampus HPA axis dysfunction
  • 11. Psychological Vulnerabilities Avoidance based coping strategies Lack of positive coping strategies •Problem solving External locus of control
  • 12. Minimal education Family instability Lack of a strong network for social support Maltreated as a child Environmental Factors
  • 13. I now better understand what caused me to develop PTSD, but what maintains the disorder?
  • 15. Onset of PTSD Directly after Trauma Acute stress disorder Not PTSD time will often heal Acute if symptoms last less than 3 months Better prognosis Chronic if persists 3 months or mother Delayed onset More guarded prognosis At least 6 months Reason for delayed onset is unknown
  • 16. Traumatic event Intense fear and anxiety surrounding cars Avoid using your car on highway You temporarily suppress your anxiety and fear Thoughts becomes more intrusive and common Significant dysfunction and distress Bike to the doctors office
  • 17.
  • 18. This sounds serious, is there anyway to treat this disorder?
  • 20. E X P O S U R E Traumatic event car crash Intense fear and anxiety surrounding cars Avoid using your car on highway Expose patient to the fear Overcome fears Reduce avoidance and withdrawal Allow you to drive your car Coping strategies + CS, control
  • 21. Cognitive Processing Therapy Repeatedly talking about the problem with the patient Correct assumptions about the trauma •Self blame •Feelings of guilt Shift in cognition  shift in behavior
  • 24. Wow, What an informative answer. Looks like my life will be able to go back to normal after all.
  • 25. I’m so happy I can drive to the beach again
  • 26. Bisson, J. I. (2007). Post-traumatic stress disorder. Occupational Medicine, 57(6), 399-403. Bremner, J., Randall, P., Vermetten, E., Staib, L., Bronen, R. A., Mazure, C., et al. (1997). Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse-a preliminary report. Biological Psychiatry, 41(1), 23-32. Breslau, N., Davis, G. C., & Andreski, P. (1995). Risk factors for PTSD- related traumatic events: A prospective analysis. The American Journal of Psychiatry, 152(4), 529-535. References
  • 27. Foa, E. B., Keane, T. M., Friedman, M. J., & Cohen, J. A. (Eds.). (2009). Effective treatments for PTSD. New York, NY: The Guilford Press. Keane, T. M., Marshall, A. D., & Taft, C. T. (2006). Posttraumatic stress disorder: Etiology, epidemiology, and treatment outcome. Annual Review of Clinical Psychology, 2, 161-197. King, D. W., King, L. A., & Foy, D. W. (1996). Prewar factors in combat- related posttraumatic stress disorder: Structural equation modeling with a national sample of female and male vietnam veterans. Journal of Consulting and Clinical Psychology, 64(3), 520-531.
  • 28. Lee, H. -., Lee, M. -., Kang, R. -., Kim, H., Kim, S. -., Kee, B. -., et al. (2005). Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder. Depression and Anxiety, 21(3), 135--139. Lyons, M. J., Goldberg, J., Eisen, S. A., True, W., Tsuang, M. T., Meyer, J. M., et al. (1993). Do gnenes influence exposure to trauma? A twin study of combat. American Journal of Medical Genetics, 48(1), 22-27. Tarrier, N., Sommerfield, C., & Pilgrim, H. (199). Relatives; espressed emotion (EE) and PTSD treatment outcome. Psychological Medicine, 29, 801-808.
  • 29. Van Etten, M. L., & Taylor, S. (1998). Comparative efficacy of treatments for post-traumatic stress disorder: A meta-analysis. Clinical Psychology and Psychotherapy, 5(3), 126-144. Widows, M. R., Jacobsen, P. B., & Fields, K. K.,. (2000). Relation of psychological vulnerability facotrs to posttraumatic stress disorders symptomatology in bone marrow transplant recipients. Psychosomatic Medicine, 62(6), 873-882.

Editor's Notes

  1. Although Patricia’s physical injuries have healed, a month after this life-threatening accident, she still refuses to go to McDonalds because there was one near the site of her accident, she avoids driving her car, she avoids the neighborhood where the accident took place, she is easily aroused by loud noises, and she experiences persistent flashbacks and nightmares about her traumatic car crash
  2. Slide 6: In order to be diagnosed with PTSD, a patient must have been exposed to a traumatic event, 1 month must have passed since the trauma, and a patient must display other symptoms
  3. Common misconception of PTSD is that the only cause is a traumatic event; however, if this were the case many more individuals would have developed the disorders. While we know exposure to a traumatic event plays a role in development of PTSD we must use a multidimensional approach to best understand the etiology of PTSD. While there is not a single “cause” for PTSD research suggests that in addition to the experience of a traumatic event other factors such as Generalized biological vulnerabilities, generalized psychological vulnerabilities, and Environmental Factors all of which play a role in the development of PTSD.
  4. General Biological Vulnerabilities include Genetics, a difference in the serotonin transporter gene, damage to the hippocampus, and dysfunction in the HPA axis. One twin study on male-male twins who fought during the Vietnam War found a stronger correlation in monozygotic twin pairs developing PTSD than dizygotic twins suggesting a genetic basis for PTSD. The Monozygotic twins had a .41 correlation coefficient for development of PTSD while dyzygotic twins only had a .24 correlation coefficient. Another study researching PTSD and non PTSD patients found that PTSD patients were much more likely to have two short alleles in the serotonin transporter gene. Another study’s results comparing individuals with PTSD to individuals with out the disorder suggested that those with PTSD more commonly have a smaller hippocampus. However, researchers still do not know if the loss volume in the hippocampus is a cause or an effect of PTSD. Finally, research indicates that an individual with PTSD do not have a normal functioning HPA axis which is the circuit responsible to control the body’s reaction to stress.
  5. Unlike other disorders there is not one typical courseOnset can take various forms
  6. Avoidance – short term solves the problem but can cause enhanced distress and dysfunction in future, less you will desensitize, caused increased fear and anxiety Avoidance maintains the disorder
  7. Alcohol abuse – men: 52% women: 28% (source 1) Drug abuse – men: 35% women: 27% (source 1)Used often to cope with distress an individual is suffering can actually intensify symptoms of PTSD
  8. Slide 20:Studies have found the most successful treatment for PTSD is Prolonged Exposure. I will give you an example of various steps you might go through if you were to use this treatment method. In prolonged exposure, you will not avoid fears associate with the traumatic event. Instead, you will be exposed to these fears. Exposure helps patients’ overcome these fears rather then suppressing them. This reduces symptoms of PTSD such as withdrawal and avoidance and allow you to drive your car. This treatment also includes education before the exposure so patients can learn positive coping strategies. This treatment also has two main components: imaginable and in vivo. Imaginable exposure is when a patient re lives their traumatic event through remembering it while in vivo implies a direct confrontations of fears associated with the traumatic event. For example, you might go back to the site of your car crash. During prolonged exposure, patients should go at their own pace so they feel a sense of control because a sense of control is often taken away by trauma. This treatment often takes multiple sessions but studies indicate it is the most successful way to treat PTSD
  9. Slide 21: Another treatment method is Cognitive-processing Therapy. This therapy involves repeatedly talking about the event to a psychiatrist. Through these sessions a psychiatrist aims to change the way an individual thinks about the traumatic event for example he or she will try to change feelings of self-blame or guilt. Cognitive processing therapy depends on the principle that if you can change and individuals thoughts it will change their behavior.
  10. Slide 22: Medication can also be used in treatment however there is more evidence that Prolonged exposure and cognitive processing therapy are more effective treatments than medication. Medication will hide the symptoms rather than permanently reduce and eliminate them. The most common medication are SSRIs, which reduces anxiety by inhibiting the reuptake of serotonin
  11. Slide 23: There are also other treatments for PTSD. Various studies indicate that strong social support plays a large role in determining the success of a treatment. Eye Movement Desensitization and Reprocessing is a controversial treatment for PTSD. While studies have suggested the treatment has been successful many argue that the success is due to the exposure part of the treatment rather than the eye movement. Research has also shown that Virtual Reality can be used as another form of exposure to reduce PTSD symptoms.