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Sebumeter
Dr. KUMARA S W A M Y S A M A N T H U L A
A S S O C I A T E P R O F E S S O R
F a c u l t y o f P h a r m a c e u t i c a l S c i e n c e
A S S A M D O W N T O W N U N I V E R S I T Y
 Excess oiliness or excess dryness affects cosmetic
appearance of the skin.
 Hence, estimation of oiliness is important to decide
on the correct regimen to achieve cosmesis.
 Besides, sebum affects the permeability of skin and
absorptivity of water, protects against bacteria and
fungi, limits evaporation and affects permeation of
pharmaceutical preparations and other active or
non-active substances.
 Hence measurement of natural presence of sebum
on human skin particularly facial skin is a matter of
current interest amongst dermatologists and
pharmaceutical and cosmetic manufacturers.
Uses of sebumeter
 To classify skin type as dry, normal and oily in an objective
manner
 To prescribe pharmaceuticals/ cosmetics suitable to the
patient’s skin type to increase efficacy and minimize side
effects
 Pre-placement examination for correct analysis of skin type
in the field of occupational medicine e.g. person of dry skin
type may not suitable to work in chemical industry involving
use of acid and alkalies
 To make early diagnosis of senile asteotosis
 To measure skin-cleaning effects of soaps
 To do preliminary screening and follow up of patients with
hyper-androgenic states
 To study the endocrine control of sebaceous follicle in
women for assessing hormonal ageing
 To study the correlation between ‘bad hair days’ (days
during which most women find their hair difficult to
manage), sebum secretion, and menstrual cycle
 To study sebo-suppressive effects of certain anti- acne
medications like retinoic acid in treatment of acne
vulgaris
 To study the sebaceous gland activity in diabetics, in
whom, the activity of the glands is decreased
 Heterogenous components of sebum are produced
from secretion of sebaceous glands, fat of
keratinous layer and remnants of perspiration.
 Sebum is a complex and variable mixture of lipids
like glycerides, free fatty acids, wax esters,
squalene, cholesterol esters, and cholesterol.
Methods of sebum estimation
 Many methods have been used in the past for collecting
lipids from human skin and measuring their production.
 They include swabbing by pads soaked in organic
solvents such as hexane or ether, washing lipid solvents
over areas of skin circumscribed by rings or caps.
 Strauss and Pochi devised a simple, reproducible but
time consuming method for measuring human sebaceous
secretion.
 They placed a pad of absorbent cigarette papers for 3
hrs on a delimited area of forehead and then
extracted the sebum with diethyl ether.
 Facial skin is usually classified as dry, normal and
oily.
 However skin type does not match the amount of
sebum secreted.
 Thus, simple and subjective classification is of very
limited use and it should be re-evaluated by using
an objective and standardized measuring tool like
sebumeter.
 It is a device by which sebum can be quantified
from any area of skin in an objective manner
 Different types of apparatus exist for measuring the
amount of sebum.
 They are based on the principle that when sebum is
deposited on a translucent element, such as a frosted
glass or plastic plate or strip, the element becomes
increasingly transparent (greater the amount of sebum
applied, the greater the transparency produced).
 Light passing through this sebum covered translucent
element is then measured using photoelectric receiver.
Mechanism of sebum measurement by
sebumeter
 The measurement is based on the principle of
grease- spot photometry [Figure 1].
 The measuring head of the cassette with its special
tape is placed on the skin.
 It is then inserted into a slot of the device, where
the transparency is measured by a light source
passing through the tape.
 A photocell measures the transparency.
 A microprocessor calculates the result, which is
shown on the display in mg sebum/cm2 of the skin.
Sebumeter probe (Cassette)
 The Sebumeter-cassette contains a matt synthetic tape,
0.1 mm thick.
 The measuring head of the cassette exposes a 64 mm2
section of the tape, which is transported forward by a
trigger at the side of the cassette for the next
measurement.
 The measuring time of 30 seconds is controlled by a
clock set in the device.
 Sebum is then determined as explained in the
measurement principle above.
 The instrument has an accuracy of ± 5%.
 The reading of sebum may be displayed as a number or
as type of skin i.e. Dry; Dry/ Normal; Normal;
Normal/Oily; Oily.
Pros and cons of using a sebumeter
 Sebumeter is a simple and quick (requires less than
a minute) method of sebum estimation.
 The instrument is portable and its use requires little
training.
 The only disadvantage is the cost of the instrument
as well as the consumable viz., the cassette.
 Thus with increasing emphasis on skin enhancement,
sebumeter is likely to become a common implement
in dermatologist’s office.
16. Sebumeter.pdf

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16. Sebumeter.pdf

  • 1. Sebumeter Dr. KUMARA S W A M Y S A M A N T H U L A A S S O C I A T E P R O F E S S O R F a c u l t y o f P h a r m a c e u t i c a l S c i e n c e A S S A M D O W N T O W N U N I V E R S I T Y
  • 2.  Excess oiliness or excess dryness affects cosmetic appearance of the skin.  Hence, estimation of oiliness is important to decide on the correct regimen to achieve cosmesis.  Besides, sebum affects the permeability of skin and absorptivity of water, protects against bacteria and fungi, limits evaporation and affects permeation of pharmaceutical preparations and other active or non-active substances.
  • 3.  Hence measurement of natural presence of sebum on human skin particularly facial skin is a matter of current interest amongst dermatologists and pharmaceutical and cosmetic manufacturers.
  • 4. Uses of sebumeter  To classify skin type as dry, normal and oily in an objective manner  To prescribe pharmaceuticals/ cosmetics suitable to the patient’s skin type to increase efficacy and minimize side effects  Pre-placement examination for correct analysis of skin type in the field of occupational medicine e.g. person of dry skin type may not suitable to work in chemical industry involving use of acid and alkalies  To make early diagnosis of senile asteotosis  To measure skin-cleaning effects of soaps  To do preliminary screening and follow up of patients with hyper-androgenic states
  • 5.  To study the endocrine control of sebaceous follicle in women for assessing hormonal ageing  To study the correlation between ‘bad hair days’ (days during which most women find their hair difficult to manage), sebum secretion, and menstrual cycle  To study sebo-suppressive effects of certain anti- acne medications like retinoic acid in treatment of acne vulgaris  To study the sebaceous gland activity in diabetics, in whom, the activity of the glands is decreased
  • 6.  Heterogenous components of sebum are produced from secretion of sebaceous glands, fat of keratinous layer and remnants of perspiration.  Sebum is a complex and variable mixture of lipids like glycerides, free fatty acids, wax esters, squalene, cholesterol esters, and cholesterol.
  • 7. Methods of sebum estimation  Many methods have been used in the past for collecting lipids from human skin and measuring their production.  They include swabbing by pads soaked in organic solvents such as hexane or ether, washing lipid solvents over areas of skin circumscribed by rings or caps.  Strauss and Pochi devised a simple, reproducible but time consuming method for measuring human sebaceous secretion.  They placed a pad of absorbent cigarette papers for 3 hrs on a delimited area of forehead and then extracted the sebum with diethyl ether.
  • 8.  Facial skin is usually classified as dry, normal and oily.  However skin type does not match the amount of sebum secreted.  Thus, simple and subjective classification is of very limited use and it should be re-evaluated by using an objective and standardized measuring tool like sebumeter.  It is a device by which sebum can be quantified from any area of skin in an objective manner
  • 9.  Different types of apparatus exist for measuring the amount of sebum.  They are based on the principle that when sebum is deposited on a translucent element, such as a frosted glass or plastic plate or strip, the element becomes increasingly transparent (greater the amount of sebum applied, the greater the transparency produced).  Light passing through this sebum covered translucent element is then measured using photoelectric receiver.
  • 10.
  • 11. Mechanism of sebum measurement by sebumeter  The measurement is based on the principle of grease- spot photometry [Figure 1].  The measuring head of the cassette with its special tape is placed on the skin.  It is then inserted into a slot of the device, where the transparency is measured by a light source passing through the tape.  A photocell measures the transparency.  A microprocessor calculates the result, which is shown on the display in mg sebum/cm2 of the skin.
  • 12. Sebumeter probe (Cassette)  The Sebumeter-cassette contains a matt synthetic tape, 0.1 mm thick.  The measuring head of the cassette exposes a 64 mm2 section of the tape, which is transported forward by a trigger at the side of the cassette for the next measurement.  The measuring time of 30 seconds is controlled by a clock set in the device.  Sebum is then determined as explained in the measurement principle above.  The instrument has an accuracy of ± 5%.  The reading of sebum may be displayed as a number or as type of skin i.e. Dry; Dry/ Normal; Normal; Normal/Oily; Oily.
  • 13. Pros and cons of using a sebumeter  Sebumeter is a simple and quick (requires less than a minute) method of sebum estimation.  The instrument is portable and its use requires little training.  The only disadvantage is the cost of the instrument as well as the consumable viz., the cassette.  Thus with increasing emphasis on skin enhancement, sebumeter is likely to become a common implement in dermatologist’s office.