The document discusses obesity, its causes, measurements, classifications, and treatments including metabolic/bariatric surgery. It defines obesity as a chronic disease influenced by genetics and environment. Surgical treatments include restrictive procedures like gastric banding and sleeve gastrectomy, as well as malabsorptive procedures like Roux-en-Y gastric bypass and biliopancreatic diversion that restrict food intake and interfere with nutrient absorption. The goal of metabolic surgery is to achieve significant and long-term weight loss and improve medical comorbidities beyond just diet and lifestyle changes.
This case study describes a 65-year-old post-menopausal woman presenting with abnormal uterine bleeding who was diagnosed with endometrial adenocarcinoma. After surgical staging and pathology confirming Grade 3 endometrioid adenocarcinoma with myometrial invasion and lymphovascular space invasion, the patient is a candidate for vaginal brachytherapy based on her risk factors and the PORTEC-2 trial results showing vaginal brachytherapy alone is equivalent to external beam radiation for intermediate-high risk early stage endometrial cancer. Close follow up is recommended given her negative prognostic indicators.
Neuroendocrine tumors (NETs) can secrete functional hormones and commonly metastasize to the liver. Management depends on the specific tumor type and location. Carcinoid tumors of the appendix smaller than 1 cm require only appendectomy, while larger or higher grade tumors warrant right hemicolectomy. Multiple endocrine neoplasia (MEN) syndromes involve specific tumor patterns and genetic mutations. A woman with a 0.8 cm well-differentiated carcinoid tumor in her appendix requires no further intervention after appendectomy.
Pancreatic neuroendocrine tumors (pNETs) are the most common endocrine tumors of the abdomen. Insulinomas are a functional type of pNET that secretes excess insulin, causing hypoglycemia. Insulinomas are typically benign and solitary tumors located within the pancreas that are challenging to localize due to their small size. Diagnosis involves demonstrating hypoglycemia along with inappropriately elevated insulin and C-peptide levels during fasting. Localization methods include CT, MRI, EUS, and arterial calcium stimulation with selective catheterization and venous sampling, with EUS and arterial calcium stimulation being the most sensitive. Complete surgical resection remains the primary treatment for insulinomas.
This document discusses metabolic surgery, which aims to cure or improve metabolic syndrome through gastrointestinal procedures like gastric bypass and sleeve gastrectomy. Metabolic syndrome is defined by conditions like elevated blood glucose, blood pressure, triglycerides, and reduced HDL cholesterol. These surgeries have been shown to significantly resolve type 2 diabetes in many patients through mechanisms involving changes in gastrointestinal hormones and adipokines independent of weight loss. Complications from metabolic surgeries are generally minor, with mortality rates below 1% showing it is a highly safe and effective treatment when lifestyle changes fail to control metabolic syndrome and diabetes.
Morbid obesity is diagnosed using body mass index, body fat percentage, and waist circumference measurements. Treatment involves lifestyle changes including diet, exercise, and behavior therapy as well as medications or surgery. Surgical options include restrictive procedures like gastric banding and sleeve gastrectomy, or combined restrictive and malabsorptive procedures like Roux-en-Y gastric bypass. Complications can include leaks, infections, nutritional deficiencies, and weight regain, so patients require long-term management. Bariatric surgery is effective for treating obesity-related medical conditions and promoting significant and sustainable weight loss for eligible patients.
This document outlines considerations for obesity and surgery. It defines obesity metrics like body mass index and discusses increased risks obesity poses for surgery like higher morbidity and technical challenges. Pre-operative assessment of obesity-related medical conditions and intra/post-operative management strategies are reviewed. Both non-operative and operative treatment options for obesity are presented, with bariatric surgery shown to have better long-term outcomes than diet/exercise alone for severe obesity.
Fundamentals of bariatric and metabolic surgerymostafa hegazy
This document discusses bariatric and metabolic surgery. It begins by defining morbid obesity and listing its causes and health risks. It then outlines the steps in treating morbid obesity, including pharmacotherapy, diet/exercise, and bariatric surgery. Several types of bariatric surgeries are described, including restrictive, malabsorptive, and combined procedures. Potential complications are listed. The document also discusses how bariatric surgery can help treat and potentially cure diabetes and other obesity-related diseases by altering gut hormones like GLP-1 and PYY.
The document discusses obesity, its causes, measurements, classifications, and treatments including metabolic/bariatric surgery. It defines obesity as a chronic disease influenced by genetics and environment. Surgical treatments include restrictive procedures like gastric banding and sleeve gastrectomy, as well as malabsorptive procedures like Roux-en-Y gastric bypass and biliopancreatic diversion that restrict food intake and interfere with nutrient absorption. The goal of metabolic surgery is to achieve significant and long-term weight loss and improve medical comorbidities beyond just diet and lifestyle changes.
This case study describes a 65-year-old post-menopausal woman presenting with abnormal uterine bleeding who was diagnosed with endometrial adenocarcinoma. After surgical staging and pathology confirming Grade 3 endometrioid adenocarcinoma with myometrial invasion and lymphovascular space invasion, the patient is a candidate for vaginal brachytherapy based on her risk factors and the PORTEC-2 trial results showing vaginal brachytherapy alone is equivalent to external beam radiation for intermediate-high risk early stage endometrial cancer. Close follow up is recommended given her negative prognostic indicators.
Neuroendocrine tumors (NETs) can secrete functional hormones and commonly metastasize to the liver. Management depends on the specific tumor type and location. Carcinoid tumors of the appendix smaller than 1 cm require only appendectomy, while larger or higher grade tumors warrant right hemicolectomy. Multiple endocrine neoplasia (MEN) syndromes involve specific tumor patterns and genetic mutations. A woman with a 0.8 cm well-differentiated carcinoid tumor in her appendix requires no further intervention after appendectomy.
Pancreatic neuroendocrine tumors (pNETs) are the most common endocrine tumors of the abdomen. Insulinomas are a functional type of pNET that secretes excess insulin, causing hypoglycemia. Insulinomas are typically benign and solitary tumors located within the pancreas that are challenging to localize due to their small size. Diagnosis involves demonstrating hypoglycemia along with inappropriately elevated insulin and C-peptide levels during fasting. Localization methods include CT, MRI, EUS, and arterial calcium stimulation with selective catheterization and venous sampling, with EUS and arterial calcium stimulation being the most sensitive. Complete surgical resection remains the primary treatment for insulinomas.
This document discusses metabolic surgery, which aims to cure or improve metabolic syndrome through gastrointestinal procedures like gastric bypass and sleeve gastrectomy. Metabolic syndrome is defined by conditions like elevated blood glucose, blood pressure, triglycerides, and reduced HDL cholesterol. These surgeries have been shown to significantly resolve type 2 diabetes in many patients through mechanisms involving changes in gastrointestinal hormones and adipokines independent of weight loss. Complications from metabolic surgeries are generally minor, with mortality rates below 1% showing it is a highly safe and effective treatment when lifestyle changes fail to control metabolic syndrome and diabetes.
Morbid obesity is diagnosed using body mass index, body fat percentage, and waist circumference measurements. Treatment involves lifestyle changes including diet, exercise, and behavior therapy as well as medications or surgery. Surgical options include restrictive procedures like gastric banding and sleeve gastrectomy, or combined restrictive and malabsorptive procedures like Roux-en-Y gastric bypass. Complications can include leaks, infections, nutritional deficiencies, and weight regain, so patients require long-term management. Bariatric surgery is effective for treating obesity-related medical conditions and promoting significant and sustainable weight loss for eligible patients.
This document outlines considerations for obesity and surgery. It defines obesity metrics like body mass index and discusses increased risks obesity poses for surgery like higher morbidity and technical challenges. Pre-operative assessment of obesity-related medical conditions and intra/post-operative management strategies are reviewed. Both non-operative and operative treatment options for obesity are presented, with bariatric surgery shown to have better long-term outcomes than diet/exercise alone for severe obesity.
Fundamentals of bariatric and metabolic surgerymostafa hegazy
This document discusses bariatric and metabolic surgery. It begins by defining morbid obesity and listing its causes and health risks. It then outlines the steps in treating morbid obesity, including pharmacotherapy, diet/exercise, and bariatric surgery. Several types of bariatric surgeries are described, including restrictive, malabsorptive, and combined procedures. Potential complications are listed. The document also discusses how bariatric surgery can help treat and potentially cure diabetes and other obesity-related diseases by altering gut hormones like GLP-1 and PYY.
The document discusses pancreatic endocrine tumors (PETs), including:
1. It describes different types of PETs that are named based on the hormone they secrete (e.g. insulinoma, gastrinoma, glucagonoma).
2. For each tumor type, it provides the hormone responsible, associated clinical symptoms, and general principles of medical treatment.
3. Surgical treatment options for PETs depend on the location within the pancreas, with distal pancreatectomy for body/tail tumors and pancreaticoduodenectomy for head/uncinate tumors.
Insulinomas are rare tumors of the pancreas that produce excess insulin, causing hypoglycemia (low blood sugar). Symptoms include confusion, dizziness, and seizures. Insulinomas most commonly occur in adults ages 40-60 and are usually benign. Diagnosis involves blood tests during hypoglycemic episodes and imaging scans to locate tumors. Surgery to remove the tumor is the primary treatment, while medications may help if the tumor cannot be fully removed.
Tumour markers are substances released by cancer cells or produced by the body in response to cancer that can help detect and monitor cancer. They include enzymes, hormones, and antigens. Some common tumour markers are PSA for prostate cancer, CA125 for ovarian cancer, and CEA for colorectal cancer. While elevated levels can indicate cancer, tumour markers can also be increased in some non-cancerous conditions. Researchers are studying tumour markers to improve cancer detection, diagnosis, treatment evaluation and monitoring for recurrence.
Bariatric surgery is used to treat morbid obesity through restrictive or malabsorptive procedures like gastric bypass. Anesthesia for bariatric surgery requires special considerations due to patient comorbidities and positioning. Obese patients have increased volumes of distribution and drug dosing is often based on lean or adjusted body weight. Careful attention must be paid to fluid management, ventilation, and emergence from anesthesia due to postoperative pulmonary risks in these patients.
An obese patient presents additional challenges for anesthesia. Their cardiovascular system must work harder to meet increased metabolic demands, which can lead to left ventricular hypertrophy, pulmonary hypertension, and right heart failure. Respiratory function is also impaired with reduced lung volumes, ventilation/perfusion mismatch, and increased risk of obstructive sleep apnea. Careful consideration of fluid management and vascular access is needed due to differences in physiology compared to non-obese patients.
This case study summarizes a 38-year old female patient presenting with breast pain, nipple tenderness, and bloody discharge. Her medical history includes a diagnosis of tennis elbow. Laboratory tests and cytology reports were conducted. She was diagnosed with breast cancer and prescribed a treatment plan including Aceclofenac, Pantoprazole, Cefuroxime, and Ormeloxifene. The pharmacist advised avoiding weight lifting, sufficient rest, maintaining a normal body weight, exercising regularly, and avoiding heavy lifting.
Pancreatic endocrine tumors are rare, occurring in approximately 5 per 1,000,000 people per year. The most common types are insulinomas, gastrinomas, vipomas, and glucagonomas. Insulinomas typically present with hypoglycemic symptoms and are usually benign and solitary. Gastrinomas present with peptic ulcer disease and weight loss and are often malignant. Vipomas cause severe watery diarrhea and hypokalemia. Glucagonomas result in necrolytic migratory erythema, weight loss, and diabetes. Diagnosis involves laboratory tests and imaging like CT or MRI. Treatment depends on the type but may include surgery, chemotherapy, or symptom management. Progn
This document provides information on pancreatic carcinoma, including:
- The anatomy and blood supply of the pancreas.
- Risk factors, signs and symptoms, investigation, classification, and staging of pancreatic cancer.
- Surgical treatments including pancreaticoduodenectomy, distal pancreatectomy, and palliative procedures.
- Adjuvant therapies and palliation of advanced or unresectable pancreatic cancer.
Prostate cancer is the uncontrolled multiplication of abnormal prostate gland cell tumor formation. It can be caused by genetic factors like family history or mutations, as well as increasing age and diet. Symptoms include frequent urination, blood in the urine or seminal fluid, and bone pain. Diagnostic tests include digital rectal exam, PSA testing, biopsy, and imaging. Treatment may include radical prostatectomy surgery or other options. Post-operative care focuses on urinary elimination, infection prevention, and nutrition management. Lifestyle changes like diet, exercise, and avoiding smoking can help prevention.
This document discusses the role of chemotherapy in gynecological malignancies, specifically ovarian cancer. It notes that ovarian cancer is a leading cause of death from gynecologic cancer and chemotherapy has improved 5-year survival rates. For advanced stage ovarian cancer, the standard treatment is primary cytoreductive surgery followed by platinum-based chemotherapy. Optimal debulking to less than 1cm residual disease results in better outcomes. For unresectable tumors, neoadjuvant chemotherapy may be given followed by interval debulking surgery. The combination of carboplatin and paclitaxel is currently the standard first-line chemotherapy regimen.
Redustim a medical device class IIA based on biostimology technology that naturally stimulates adipocyte lipolysis (triglyceride hydrolysis) with release of energy and consumption of excess visceral fat.
The document discusses the rising problem of obesity in India, summarizing key statistics from NFHS surveys. It then covers the genetic, dietary, lifestyle, and environmental factors that contribute to obesity. The major sections discuss the medical management of obesity through diet, exercise and drugs, as well as the various bariatric surgery procedures like gastric bypass, gastric banding, and sleeve gastrectomy. Key details are provided on the indications, mechanisms, techniques and complications of different surgical options. Post-operative care and long-term follow up are also highlighted.
Morbid obesity and surgical managementGaurav Gupta
The document discusses morbid obesity and surgical management options. It defines morbid obesity as being 100 pounds or more overweight, or having a BMI over 40 kg/m2. Surgical procedures like gastric bypass, sleeve gastrectomy, and gastric banding are recommended when lifestyle changes fail to achieve weight loss. These procedures work by restricting food intake, slowing stomach emptying, or reducing nutrient absorption. Complications can include leaks, strictures, nutritional deficiencies, and infection, but bariatric surgery is generally effective for achieving long-term weight loss and resolving obesity-related health conditions.
Pancreatic carcinoma is the most dreaded cancer with very dismal prognosis. It is characterized by obstructive jaundice, high colored urine and clay colored stool.
Acute fatty liver of pregnancy (AFLP) is a rare liver disease that occurs in the third trimester of pregnancy, characterized by fatty infiltration of the liver. Symptoms include nausea, vomiting, abdominal pain and jaundice. It is a medical emergency requiring immediate delivery of the fetus and treatment of the mother, who may develop hepatic failure and coagulopathy. General anesthesia is preferable to neuraxial for delivery. Maternal and fetal mortality rates are less than 12% and 66% respectively with treatment.
This document discusses carcinoma of the pancreas. It notes that pancreatic cancer most commonly occurs between ages 60-80 years old, with a median age of diagnosis of 71 years. Risk factors include family history, certain genetic syndromes, tobacco use, alcohol, obesity and chronic pancreatitis. The most common symptom is jaundice. Investigations include ultrasound, CT scan and MRI. Treatment depends on staging but may include the Whipple procedure for tumors of the head of the pancreas, which involves pancreaticoduodenectomy.
Cancer of Pancreas- Easy ppt for student nursesSwatilekha Das
This document discusses pancreatic cancer. It notes that risk factors include smoking, exposure to chemicals, a high-fat diet, and conditions like diabetes and chronic pancreatitis. Common clinical manifestations are pain, jaundice, weight loss, and vague abdominal pain. Diagnostic methods include CT scans, MRI scans, ERCP, and biopsies. Surgical treatment involves removing localized tumors through procedures like pancreatectomy or Whipple resection. Medical management can include radiation, chemotherapy, and stents to relieve jaundice.
This document provides information on bariatric surgery. It begins with definitions of bariatric and discusses the increasing prevalence of bariatric procedures over time. It then covers topics like the causes and pathophysiology of obesity, degrees of obesity based on BMI, obesity-related comorbidities, options for treatment like diet, drugs and surgery. It provides details on various bariatric surgical procedures that are either restrictive, malabsorptive or a combination. Risks, guidelines for candidacy, pre and post-op care are discussed. In summary, the document is a comprehensive overview of bariatric surgery, its increasing use and role in treating severe obesity and related health conditions.
This document discusses anesthesia considerations for bariatric surgery. It defines obesity and lists common comorbidities like diabetes and hypertension. Bariatric surgery procedures aim to induce weight loss and resolve medical conditions. Risks include respiratory complications from reduced lung capacity and obesity hypoventilation syndrome. Preoperative evaluation assesses the airway, cardiovascular and pulmonary systems, sleep apnea risk, and use of weight loss medications. Polysomnography is used to diagnose sleep apnea severity.
The document discusses anesthesia considerations for bariatric surgery. It notes that obesity is associated with various comorbidities affecting the respiratory, cardiovascular, gastrointestinal and other body systems. The anesthesia plan involves a thorough preoperative evaluation of the patient's airway, cardiac function, respiratory status, risk of venous thromboembolism, and metabolic/nutritional abnormalities. Careful dosing of anesthetic drugs based on lean or total body weight is also required. The goal of anesthesia is to safely induce and maintain anesthesia for bariatric surgery while addressing the unique health risks faced by obese patients.
The document discusses pancreatic endocrine tumors (PETs), including:
1. It describes different types of PETs that are named based on the hormone they secrete (e.g. insulinoma, gastrinoma, glucagonoma).
2. For each tumor type, it provides the hormone responsible, associated clinical symptoms, and general principles of medical treatment.
3. Surgical treatment options for PETs depend on the location within the pancreas, with distal pancreatectomy for body/tail tumors and pancreaticoduodenectomy for head/uncinate tumors.
Insulinomas are rare tumors of the pancreas that produce excess insulin, causing hypoglycemia (low blood sugar). Symptoms include confusion, dizziness, and seizures. Insulinomas most commonly occur in adults ages 40-60 and are usually benign. Diagnosis involves blood tests during hypoglycemic episodes and imaging scans to locate tumors. Surgery to remove the tumor is the primary treatment, while medications may help if the tumor cannot be fully removed.
Tumour markers are substances released by cancer cells or produced by the body in response to cancer that can help detect and monitor cancer. They include enzymes, hormones, and antigens. Some common tumour markers are PSA for prostate cancer, CA125 for ovarian cancer, and CEA for colorectal cancer. While elevated levels can indicate cancer, tumour markers can also be increased in some non-cancerous conditions. Researchers are studying tumour markers to improve cancer detection, diagnosis, treatment evaluation and monitoring for recurrence.
Bariatric surgery is used to treat morbid obesity through restrictive or malabsorptive procedures like gastric bypass. Anesthesia for bariatric surgery requires special considerations due to patient comorbidities and positioning. Obese patients have increased volumes of distribution and drug dosing is often based on lean or adjusted body weight. Careful attention must be paid to fluid management, ventilation, and emergence from anesthesia due to postoperative pulmonary risks in these patients.
An obese patient presents additional challenges for anesthesia. Their cardiovascular system must work harder to meet increased metabolic demands, which can lead to left ventricular hypertrophy, pulmonary hypertension, and right heart failure. Respiratory function is also impaired with reduced lung volumes, ventilation/perfusion mismatch, and increased risk of obstructive sleep apnea. Careful consideration of fluid management and vascular access is needed due to differences in physiology compared to non-obese patients.
This case study summarizes a 38-year old female patient presenting with breast pain, nipple tenderness, and bloody discharge. Her medical history includes a diagnosis of tennis elbow. Laboratory tests and cytology reports were conducted. She was diagnosed with breast cancer and prescribed a treatment plan including Aceclofenac, Pantoprazole, Cefuroxime, and Ormeloxifene. The pharmacist advised avoiding weight lifting, sufficient rest, maintaining a normal body weight, exercising regularly, and avoiding heavy lifting.
Pancreatic endocrine tumors are rare, occurring in approximately 5 per 1,000,000 people per year. The most common types are insulinomas, gastrinomas, vipomas, and glucagonomas. Insulinomas typically present with hypoglycemic symptoms and are usually benign and solitary. Gastrinomas present with peptic ulcer disease and weight loss and are often malignant. Vipomas cause severe watery diarrhea and hypokalemia. Glucagonomas result in necrolytic migratory erythema, weight loss, and diabetes. Diagnosis involves laboratory tests and imaging like CT or MRI. Treatment depends on the type but may include surgery, chemotherapy, or symptom management. Progn
This document provides information on pancreatic carcinoma, including:
- The anatomy and blood supply of the pancreas.
- Risk factors, signs and symptoms, investigation, classification, and staging of pancreatic cancer.
- Surgical treatments including pancreaticoduodenectomy, distal pancreatectomy, and palliative procedures.
- Adjuvant therapies and palliation of advanced or unresectable pancreatic cancer.
Prostate cancer is the uncontrolled multiplication of abnormal prostate gland cell tumor formation. It can be caused by genetic factors like family history or mutations, as well as increasing age and diet. Symptoms include frequent urination, blood in the urine or seminal fluid, and bone pain. Diagnostic tests include digital rectal exam, PSA testing, biopsy, and imaging. Treatment may include radical prostatectomy surgery or other options. Post-operative care focuses on urinary elimination, infection prevention, and nutrition management. Lifestyle changes like diet, exercise, and avoiding smoking can help prevention.
This document discusses the role of chemotherapy in gynecological malignancies, specifically ovarian cancer. It notes that ovarian cancer is a leading cause of death from gynecologic cancer and chemotherapy has improved 5-year survival rates. For advanced stage ovarian cancer, the standard treatment is primary cytoreductive surgery followed by platinum-based chemotherapy. Optimal debulking to less than 1cm residual disease results in better outcomes. For unresectable tumors, neoadjuvant chemotherapy may be given followed by interval debulking surgery. The combination of carboplatin and paclitaxel is currently the standard first-line chemotherapy regimen.
Redustim a medical device class IIA based on biostimology technology that naturally stimulates adipocyte lipolysis (triglyceride hydrolysis) with release of energy and consumption of excess visceral fat.
The document discusses the rising problem of obesity in India, summarizing key statistics from NFHS surveys. It then covers the genetic, dietary, lifestyle, and environmental factors that contribute to obesity. The major sections discuss the medical management of obesity through diet, exercise and drugs, as well as the various bariatric surgery procedures like gastric bypass, gastric banding, and sleeve gastrectomy. Key details are provided on the indications, mechanisms, techniques and complications of different surgical options. Post-operative care and long-term follow up are also highlighted.
Morbid obesity and surgical managementGaurav Gupta
The document discusses morbid obesity and surgical management options. It defines morbid obesity as being 100 pounds or more overweight, or having a BMI over 40 kg/m2. Surgical procedures like gastric bypass, sleeve gastrectomy, and gastric banding are recommended when lifestyle changes fail to achieve weight loss. These procedures work by restricting food intake, slowing stomach emptying, or reducing nutrient absorption. Complications can include leaks, strictures, nutritional deficiencies, and infection, but bariatric surgery is generally effective for achieving long-term weight loss and resolving obesity-related health conditions.
Pancreatic carcinoma is the most dreaded cancer with very dismal prognosis. It is characterized by obstructive jaundice, high colored urine and clay colored stool.
Acute fatty liver of pregnancy (AFLP) is a rare liver disease that occurs in the third trimester of pregnancy, characterized by fatty infiltration of the liver. Symptoms include nausea, vomiting, abdominal pain and jaundice. It is a medical emergency requiring immediate delivery of the fetus and treatment of the mother, who may develop hepatic failure and coagulopathy. General anesthesia is preferable to neuraxial for delivery. Maternal and fetal mortality rates are less than 12% and 66% respectively with treatment.
This document discusses carcinoma of the pancreas. It notes that pancreatic cancer most commonly occurs between ages 60-80 years old, with a median age of diagnosis of 71 years. Risk factors include family history, certain genetic syndromes, tobacco use, alcohol, obesity and chronic pancreatitis. The most common symptom is jaundice. Investigations include ultrasound, CT scan and MRI. Treatment depends on staging but may include the Whipple procedure for tumors of the head of the pancreas, which involves pancreaticoduodenectomy.
Cancer of Pancreas- Easy ppt for student nursesSwatilekha Das
This document discusses pancreatic cancer. It notes that risk factors include smoking, exposure to chemicals, a high-fat diet, and conditions like diabetes and chronic pancreatitis. Common clinical manifestations are pain, jaundice, weight loss, and vague abdominal pain. Diagnostic methods include CT scans, MRI scans, ERCP, and biopsies. Surgical treatment involves removing localized tumors through procedures like pancreatectomy or Whipple resection. Medical management can include radiation, chemotherapy, and stents to relieve jaundice.
This document provides information on bariatric surgery. It begins with definitions of bariatric and discusses the increasing prevalence of bariatric procedures over time. It then covers topics like the causes and pathophysiology of obesity, degrees of obesity based on BMI, obesity-related comorbidities, options for treatment like diet, drugs and surgery. It provides details on various bariatric surgical procedures that are either restrictive, malabsorptive or a combination. Risks, guidelines for candidacy, pre and post-op care are discussed. In summary, the document is a comprehensive overview of bariatric surgery, its increasing use and role in treating severe obesity and related health conditions.
This document discusses anesthesia considerations for bariatric surgery. It defines obesity and lists common comorbidities like diabetes and hypertension. Bariatric surgery procedures aim to induce weight loss and resolve medical conditions. Risks include respiratory complications from reduced lung capacity and obesity hypoventilation syndrome. Preoperative evaluation assesses the airway, cardiovascular and pulmonary systems, sleep apnea risk, and use of weight loss medications. Polysomnography is used to diagnose sleep apnea severity.
The document discusses anesthesia considerations for bariatric surgery. It notes that obesity is associated with various comorbidities affecting the respiratory, cardiovascular, gastrointestinal and other body systems. The anesthesia plan involves a thorough preoperative evaluation of the patient's airway, cardiac function, respiratory status, risk of venous thromboembolism, and metabolic/nutritional abnormalities. Careful dosing of anesthetic drugs based on lean or total body weight is also required. The goal of anesthesia is to safely induce and maintain anesthesia for bariatric surgery while addressing the unique health risks faced by obese patients.
This document discusses ovarian tumors. It begins by describing the anatomy of the ovaries including their size, shape, and microscopic structures like the cortex and medulla. It then discusses ovarian ligaments, blood supply, nerve supply, and oogenesis. Various types of ovarian masses are outlined including functional cysts, inflammatory cysts, endometriomas, and benign and malignant neoplasms. Specific cysts like follicular cysts, corpus luteal cysts, and dermoid cysts are described in detail. Polycystic ovarian syndrome is also explained comprehensively. The document concludes with classifications of benign ovarian tumors and images of mucinous, serous, and dermoid cysts.
breast cancer, diagnosis of breast cancer , aetiology of breast cancer, pathophysiologyy of breast cancers, drugs for the treatment of breast cancers, counselling points for breast cancers and education , surgical inyerventions in breast cancer, types of surgical intervention , chemotherapy in breast cancers,
it cinstitutes the most common form of complications encountered in eclampsia. it is potentialy curable if diagnosed and treated early in course. this is the state of affairs in MKCG Medical College, Berhampur, ODISHA, INDIA
This document provides an overview of obesity, including its definition, prevalence, assessment, complications, and management. Some key points:
- Obesity is defined as abnormal growth of adipose tissue due to enlarged fat cells or increased fat cell number.
- Over 1.5 billion adults worldwide are overweight or obese, with the highest rates in the US. Obesity is a risk factor for many chronic diseases.
- Assessment methods include BMI, skin fold thickness, and waist circumference. Complications include increased risk of heart disease, diabetes, and some cancers.
- Management involves diet, exercise, behavior modification, pharmacotherapy, and sometimes surgery. Treatment aims to reduce calorie intake and increase energy expenditure to promote weight loss
PANEL DISCUSSION MANAGEMENT OF PCOS WOMB to TOMB . PANELISTS : Dr.Chitra...Lifecare Centre
This document summarizes a panel discussion on the management of polycystic ovarian syndrome (PCOS) from womb to tomb. The panel was moderated by Dr. Sharda Jain and included several specialists. PCOS has a continuum from early pre-pubertal years through menopause. Common symptoms in adolescents include menstrual irregularity, hyperandrogenism, acne, and hirsutism. Menstrual irregularity needs treatment to reduce endometrial cancer risk. Diagnosis involves evaluating hormones, blood sugar, and polycystic ovaries on ultrasound. Treatment focuses on managing clinical symptoms specific to each patient.
The document discusses endometrial hyperplasia and various types of uterine cancers. It defines endometrium as the inner lining of the uterine wall that grows and sheds during menstruation. It describes endometrial hyperplasia as an increased proliferation of endometrial glands relative to the stroma. Endometrial hyperplasia is classified as simple, complex, or atypical depending on the presence of cell changes. The document also discusses endometrial carcinoma, the most common type of which is adenocarcinoma arising from the endometrium. Less common types include sarcomas arising from the uterine stroma or myometrium. Risk factors, diagnosis, staging, treatment, and
The document discusses definitions and classifications of obesity according to various medical references and the WHO. It provides the WHO classification of BMI ranges from underweight to super obese. It also discusses factors that contribute to obesity including genetics, lifestyle, environment and various hormones and brain regions involved in regulating appetite and energy balance. Surgical procedures for treating obesity such as gastric bypass are also mentioned.
This document discusses anesthesia considerations for bariatric surgery. It begins with definitions of obesity classifications based on BMI. It then discusses the increased risks that obese patients face from cardiovascular and pulmonary complications. Key points in the anesthetic management include careful preoperative evaluation and optimization of comorbidities, strategies for airway management and ventilation given the increased risk of difficulties, appropriate patient positioning and monitoring during surgery, and thromboprophylaxis given the risk of VTE. Overall anesthetic goals are to prevent hypoxemia and carefully manage any cardiovascular or pulmonary issues.
Polycystic Ovarian Syndrome (PCOS) is a hormonal disorder common among women of reproductive age, affecting around 5-10% of women. It is characterized by enlarged ovaries with multiple small cysts, irregular or absent menstrual periods, excess androgen and male pattern hair growth. The exact cause is unknown but involves genetic and environmental factors such as obesity and insulin resistance. The long term effects of PCOS include an increased risk of type 2 diabetes, cardiovascular disease, endometrial cancer and infertility. Treatment focuses on managing symptoms such as irregular periods, excess hair growth and weight loss through lifestyle changes and medication.
This document discusses abnormal uterine bleeding (AUB). It defines AUB and normal menstruation. It describes various clinical types of AUB and potential causes. Evaluation involves history, examination, and investigations. Treatment options include medical approaches like hormonal therapies and surgical procedures like endometrial ablation. Dysfunctional uterine bleeding is discussed in depth as the most common cause of AUB.
the above presentation is about obesity starting from explaining what is it, its prevalence, its consequence and its treatments.
the PowerPoint presentation includes the latest treatments discovered for obesity and and its benefits and efficacy ,
Oncology Nursing Nurse Licensure Examination Review discusses cancer and neoplasia, including the characteristics and nomenclature of benign and malignant tumors. It covers the etiology, carcinogenesis, diagnosis, staging, treatment, and nursing management of cancer including assessment, interventions to promote nutrition and relieve symptoms, and managing complications. Specifically regarding colon cancer, it discusses risk factors, pathophysiology, diagnostic findings, medical and surgical management, and pre- and post-operative nursing care including management of a colostomy.
Oncology Nursing Nurse Licensure Examination Review discusses key concepts in oncology nursing including cancer pathophysiology, risk factors, screening, staging, treatment options, and nursing management of complications. Specific cancers reviewed include breast cancer and colon cancer. Nursing interventions focus on preoperative teaching, postoperative care including wound care and pain management, promoting activity and nutrition, and managing common complications.
This document provides information about obesity, including definitions, classifications, causes, comorbidities, and treatments. It discusses:
- Definitions of obesity based on body mass index (BMI) and classifications of overweight and obesity.
- Causes of obesity including genetic, hormonal, environmental, and behavioral factors.
- Common obesity-related health conditions or comorbidities such as diabetes, heart disease, sleep apnea, cancer, and arthritis.
- Treatment options for obesity including lifestyle changes, medications, bariatric surgery procedures like gastric bypass and banding, and their risks and effectiveness. Bariatric surgery can result in significant and long-term weight loss and improvement of comorbidities.
The document provides information on tuberculosis including its definition, epidemiology, etiology, pathophysiology, classification, clinical presentation, diagnosis, management, and a sample case presentation. Tuberculosis is defined as an infectious disease caused primarily by Mycobacterium tuberculosis that usually affects the lung parenchyma. It discusses trends in global and India-specific TB incidence and mortality. Etiology and characteristics of M. tuberculosis are explained. The pathophysiology, types of TB, and typical clinical signs and symptoms are summarized. Methods for diagnosis including tests, imaging, and microbiology are covered. Management includes descriptions of first- and second-line drug regimens as well as prevention strategies. The case presentation provides details on a
The document provides information on tuberculosis including its definition, epidemiology, etiology, pathophysiology, classification, clinical presentation, diagnosis, management, and a sample case presentation. Tuberculosis is defined as an infectious disease caused primarily by Mycobacterium tuberculosis that usually affects the lung parenchyma. It discusses trends in global and India-specific TB incidence and mortality. Etiology and characteristics of M. tuberculosis are explained. The pathophysiology, types of TB, and typical clinical signs and symptoms are summarized. Diagnosis involves medical history, physical exam, tuberculin skin test, chest X-ray, microbiological tests, and blood tests. Management outlined first and second-line anti-TB drug reg
This document discusses obesity, including its historical aspects, definitions, classifications based on BMI, etiology, pathophysiology involving hormones like leptin and ghrelin, patterns of body fat distribution, health risks associated with obesity like increased risk of mortality, type 2 diabetes, cardiovascular disease, and certain cancers. It also discusses medical management of obesity through approaches like weight reduction, weight maintenance, drug therapy, and very low calorie diets.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Know the difference between Endodontics and Orthodontics.Gokuldas Hospital
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
How to Control Your Asthma Tips by gokuldas hospital.Gokuldas Hospital
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
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- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
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PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
2. MBBS From Kakatiya Medical College 1989
MD (Anaesthesiology) from Kakatiya Medical College 1994
Since 1994 practising as Consultant Anaesthesiologist and
finished 25 years of service by this August
Served as president and secretary of Nizamabad ISA city
branch
Presently working as senior faculty in Govt Medical College
and Hospital Nizamabad
3. OBESITY DEFINITION
Obesity is derived from the
latin word OBESUS
Means fattened by eating
WHO, ACOG Defines
obesity as Abnormal or
excessive fat
accumulation that
presents a risk to health
4. INCIDENCE
One third of the
American population are
obese
In India
10-15% of the population
are obese
16. OSA
Diagnosis is by POLYSOMNOGRAPHY
S snoring
T tiredness feeling
O observation of apnoea
P pressures
B BMI >30Kgs/Sq Mtr
A age >50 yrs
N neck circumference >40 cm
G male gender
YES ANSWER >3 HIGHRISK OF OSA
17. 3 GASTROINTESTINAL
Increased incidence of GERD
Decreased pressure of of LES tone
Impaired oesophageal and gastric mobility due to
gastroparesis
Increased incidence of Barrets
oesophagus,adenocarcinomas of gastric cardia
Colon cancers ,pancreatic cancers
Fatty liver,gall stones,hepato cellular carcinomas
18. 4 RENAL SYSTEM
Because of increased COP GFR increases
Increased fat produeces Renin,Angiotensin and
Aldosterone levels which causes sodium retention and
hypertension
Angiotensin produces constiction of efferent arterioles
leading to proteinuria
19. 5 ENDOCRINAL SYSTEM
Increased incidence of DM
T3,T4,TSH levels are normal in obese
PCOS (1)Menustrual irregularities,
(2) Hyperandrogenism
(3) Polycystic ovaries on US
Increased levels of TG, and LDL
Decreased levels of HDL
24. Appropriate sized gowns
Adequate monitoring equipment
Appropriate sized BP cuffs
Adequate staff must be there
Record weight,height and BMI
Strapping should be done to prevent fall from table
Two OT tables keep side by side if she weighs >150Kgs
27. Call experienced senior anaesthesiologist
Optimise co morbid conditions
Two anaesthesiologists are better than one
Central neuraxial block is safer than general
For painless labor epidural catheter should be placed
in labor suite
Take the help of USG in difficult cases to know the
depth of space
28. PRE OP PREPARATION
Detailed history and examination should be done
Assessment of airway and spine should be done
Evaluate intubating conditions byMallampati grading
Inspection of oropharynx for excessive palatal soft
tissues
Neck circumference 40 cm 5% chance of difficult
intubation 60 cm 35% of difficult intubation
Investigations : Complete hemogram,Coagulation
profile,FBS,RFT,LFT,Lipid profile,TFT,ECG,2D
Echo,Ultra sound abdomen
37. GENERAL ANAESTHESIA
PATIENT REFUSAL
COAGULATION ABNORMALITIES
INFECTION AT THE SITE
UN CORRECTED HYPOVOLEMIA
ANAPHYLAXIS
FIXED CARDIAC OUTPUT STATES
NEUROLOGICAL ABNORMALITIES
49. DEEP VEIN THROMBOSIS
Most common complication after surgery
Dynamic compression devices,stockings
Early ambulation is recommended
LMW Heparin s/c 40 mg given 12 hours prior to
surgery
Next dose 12 hrs after surgery
Continued for 5-6 days post operatively
52. CHALLENGES FACED BY
ANAESTHESIOLOGISTS
1 MULTI ORGAN AND SYSTEM ABNORMALITIES
2 DIFFICULTY IN SECURING VEINS
3 DIFFICUT SPINALS,EPIDURALS
4 DIFFICULT AIRWAY AND INTUBATION
5 POST OPERATIVE HYPOXIA
6 DEEP VEIN THROMBOSIS
53. TAKE HOME MESSAGE
OBESE PATIENTS HAVE MULTISYSTEM DISEASES
SPECIAL PRECAUTIONS TAKEN IN SHIFTING, AND
POSITIONING
REGIONAL ANAESTHESIA BETTER THAN
GENERAL
USE RAMP POSITION FOR INTUBATION
DVT PROPHYLAXIS
NO SEDATIVES IN PRE OP AND POST OP
TAP Block or Epidurals for post op pain relief