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BARIATRIC ANAESTHESIABARIATRIC ANAESTHESIA
(Anesthesia in Obese Patient(Anesthesia in Obese Patient ))
Dr. Tushar ChokshiDr. Tushar Chokshi
2
Two Worst enemy of AnesthetistTwo Worst enemy of Anesthetist
OBESITY COPD
3
4
The
heaviest
person in
medical
history was
Jon Brower
Minnoch
(USA 1941–
83)
635 kg635 kg
5
6
7
Obesity: DefinitionObesity: Definition
• A condition in which excess body fat may put
a person at health risk. (laymen)
• A chronic metabolic disorder that is primarily
induced and sustained by an over
consumption or underutilization of caloric
substrate (Medical)
• The American Heart Association (AHA)
defines obesity as body weight 30 percent
greater than the ideal body weight (Precise)
8
EquationsEquations
• Ideal body weight in Kg (IBW)
(Broca’s Index)
– Height in centimeters − 100 for men
– Height in centimeters − 105 for women
– -----------------------------------------------------
• Body mass index (BMI)
– weight in Kg / Height (m) 2
9
10
WHO DefinitionsWHO Definitions
Obese
20% > IBW
BMI > 28 – 35
Morbidly Obese
> 2 x IBW
BMI > 35
11
Obesity ClassificationObesity Classification
Overweight - BMI > 25 kg/m2
Obesity - BMI > 30 kg/m2
Morbid Obesity - BMI > 40 kg/m2 or
35 with coexisting co morbidities
Super Obese Patient - BMI > 50
kg/m2
12
My own BMIMy own BMI
• My weight is 80 kg
• My height is 5’8” (170 cm or 1.7 meter)
• So my BMI 82 / (1.7)2
is 27.68
• So I am Overweight but not obese
13
Obesity-- Disease –Death RiskObesity-- Disease –Death Risk
BMI( kg / m2 ) Class Hazard Ratio for
All Cause Death
Disease Risk
18.5 – 24.9 Normal 1 % ---
25 – 29.9 Overweight 1.16 % Increased
30 – 34.9 Obesity I 1.25 % High
35 – 39.9 Obesity II 2.96 % Very High
> 40 Obesity III 2.96 % Extremely
High
14
Height (ft'in") 5'0" 5'2" 5'4" 5'6" 5'8" 5'10" 6'0" 6'2" 6'4" 6'6"
Height (in) 60 62 64 66 68 70 72 74 76 78
BMI (kg/m2)
150 29.4 27.5 25.8 24.3 22.9 21.6 20.4 19.3 18.3 17.4
160 31.3 29.3 27.5 25.9 24.4 23.0 21.7 20.6 19.5 18.5
170 33.3 31.2 29.2 27.5 25.9 24.4 23.1 21.9 20.7 19.7
180 35.2 33.0 31.0 29.1 27.4 25.9 24.5 23.2 22.0 20.8
190 37.2 34.8 32.7 30.7 28.9 27.3 25.8 24.4 23.2 22.0
200 39.1 36.7 34.4 32.3 30.5 28.8 27.2 25.7 24.4 23.2
210 41.1 38.5 36.1 34.0 32.0 30.2 28.5 27.0 25.6 24.3
220 43.1 40.3 37.8 35.6 33.5 31.6 29.9 28.3 26.8 25.5
230 45.0 42.2 39.6 37.2 35.0 33.1 31.3 29.6 28.1 26.6
240 47.0 44.0 41.3 38.8 36.6 34.5 32.6 30.9 29.3 27.8
250 48.9 45.8 43.0 40.4 38.1 35.9 34.0 32.2 30.5 29.0
260 50.9 47.7 44.7 42.1 39.6 37.4 35.3 33.5 31.7 30.1
270 52.8 49.5 46.4 43.7 41.1 38.8 36.7 34.7 32.9 31.3
280 54.8 51.3 48.2 45.3 42.7 40.3 38.1 36.0 34.2 32.4
290 56.8 53.2 49.9 46.9 44.2 41.7 39.4 37.3 35.4 33.6
300 58.7 55.0 51.6 48.5 45.7 43.1 40.8 38.6 36.6 34.7
310 60.7 56.8 53.3 50.1 47.2 44.6 42.1 39.9 37.8 35.9
320 62.6 58.7 55.0 51.8 48.8 46.0 43.5 41.2 39.0 37.1
330 64.6 60.5 56.8 53.4 50.3 47.4 44.8 42.5 40.3 38.2
340 66.5 62.3 58.5 55.0 51.8 48.9 46.2 43.7 41.5 39.4
350 68.5 64.1 60.2 56.6 53.3 50.3 47.6 45.0 42.7 40.5
360 70.5 66.0 61.9 58.2 54.9 51.8 48.9 46.3 43.9 41.7
370 72.4 67.8 63.6 59.8 56.4 53.2 50.3 47.6 45.1 42.8
380 74.4 69.6 65.4 61.5 57.9 54.6 51.6 48.9 46.4 44.0
390 76.3 71.5 67.1 63.1 59.4 56.1 53.0 50.2 47.6 45.2
400 78.3 73.3 68.8 64.7 60.9 57.5 54.4 51.5 48.8 46.3
410 80.2 75.1 70.5 66.3 62.5 59.0 55.7 52.8 50.0 47.5
Morbidly
Obese
Overweigh
Obese
15
Incidence of ObesityIncidence of Obesity
• 23 % are obese of world population
• 5% are morbidly obese
• Mortality is 2.96 times higher in
obese
16
Twenty Years of Increasing Obesity
30.5%
22.9%
15%14.5%13.4%
0%
10%
20%
30%
40%
1960 1974 1980 1994 2000
%Obesity
Source NCHS -- JAMA 2002:14:1723-27.
17
Causes of ObesityCauses of Obesity
– Genetic predisposition
– Socialization
– Age
– Sex
– Race
– Economic status
– Psychological ( Dietary Habits )
– Cultural
– Emotional
– Environmental factors
– Cessation of smoking
18
Diseases Linked to ObesityDiseases Linked to Obesity
• Diabetes
• Coronary Heart Disease
• High Blood Pressure
• Stroke
• Arthritis
• Gastroesophageal reflux
• Cancer
• High cholesterol
• Endocrine disease
19
Diseases Linked to ObesityDiseases Linked to Obesity
• Hypertrophic Cardiomyopathy
• Infertility
• Depression
• Obstructive sleep apnea
• Gallstones
• Fatty liver
• Stress incontinence
• Venous ulcers
• End-stage kidney failure
• Sudden death
20
A 10-kg higher body weight is
associated with a 3.0-mm Hg higher
systolic and a 2.3-mm Hg higher
diastolic blood pressure. These
increases translate into an estimated
12% increased risk for CHD and 24%
increased risk for stroke
Hypertension is about 6 times
more frequent in obese subjects
than in lean men and women
21
Physical Complications of ObesityPhysical Complications of Obesity
• Heart disease
• Type II diabetes mellitus
• Hypertension
• Stroke
• Cancer (endometrial, breast, prostrate, colon)
• Gallbladder disease
• Sleep apnea
• Osteoarthritis
• Reduced fertility
• increased risk of morbidity and mortality as well as reduced
life expectancy
• Psychological & Sexual
22
Psychological ComplicationsPsychological Complications
of Obesityof Obesity
• Emotional distress
• Discrimination
• Social stigmatization
• Anxiety, fear, hostility and insecurity
23
Diabetes Mellitus Type 2Diabetes Mellitus Type 2 prevalence isprevalence is
2.9 times higher in the obese than in non-2.9 times higher in the obese than in non-
obese for those 20-75 years of age.obese for those 20-75 years of age.
Morbidity due toMorbidity due to Cardio-vascularCardio-vascular
diseasesdiseases has been reported to be almosthas been reported to be almost
90 % in those with severe obesity.90 % in those with severe obesity.
24
For
Anaesthesiologist
Concerned
25
Changes in Body system
due to Obesity
• Cardiovascular Physiology
• Respiratory Physiology
• Gastro Physiology
26
Cardiovascular PathophysiologyCardiovascular Pathophysiology
in Obesityin Obesity
• Excess body mass leads
↑ metabolic demand → ↑ Cardiac Output
For every 13.5 kg of fat gained:
– 25 miles of neovascularization occurs
– Increased CO of 0.1 L/min for each kg of fat.
↑ workload
• LVH
∀↑ Pulmonary blood flow
– Pulmonary HTN → Cor Pulmonale → Right Heart
Failure
∀ ↑ SV and SW Proportion to body weight
LVH dilatation
27
Cardiovascular PathophysiologyCardiovascular Pathophysiology
• --↑ Risk of arrhythmias
– Hypertrophy of Myocardium
– Hypoxemia
– Fatty infiltration of cardiac conduction system
↑ Catecholamines
– Sleep apnea
– Dyslipidemia
– Glucose intolerance
28
Cardiac Evaluation:Cardiac Evaluation:
in obese patientin obese patient
Ask for
• Prior MI ( Myocardial Ischemia / Infraction )
• HTN ( Hypertension )
• Angina
• PVD ( Peripheral Vascular Disease )
• Limitations in exercise tolerance
• History of orthopnea
• Paroxysmal nocturnal dyspnea
29
In ECG look forIn ECG look for
– Resting rate
– Rhythm
– Ventricular hypertrophy or strain
– Ischemic changes or evidence of Coronary Artery
Disease
– Low voltage ECG
– Axis deviation and atrial tachyarrhythmias
– LVH
– Ventricular ectopy
30
ECG Changes That May Occur in Obese IndividualsECG Changes That May Occur in Obese Individuals
Heart rate
PR interval
QRS interval
or QRS voltage
QTc
interval
QT dispersion
T Inversion
ST-T abnormalities
ST depression
Left-axis deviation
Flattening of the T wave (inferolateral leads)
Left atrial abnormalities
False-positive criteria for inferior myocardial
infarction
31
Vascular Access in obeseVascular Access in obese
Very Challenging
– Excessive fat obscures blood vessels
– Always put IV cannula ( No Scalp Veins )
– Central line placement, if indicated
32
Volume Replacement in ObeseVolume Replacement in Obese
• Adult total body water percentage is
70 % in normal individual
But
• Severely obese has total body water is 40%.
And
• In obese patient estimated blood volume is 50 ml /
kg, then 70 ml / kg in non-obese
So,
Obese patient less tolerate
fluid & blood loss during surgery
33
Volume ReplacementVolume Replacement
• Avoid rapid rehydration, to
– Lessen cardiopulmonary compromise.
• Administer Hetastarch at recommended volumes
per kilogram of IBW
– 20 mL/kg
• Albumin 5% and 25% used as indicated
– To Support circulatory volume and oncotic pressure.
• Replace blood loss with crystalloid
– 3:1 ratio
34
Respiratory PathophysiologyRespiratory Pathophysiology
in Obesityin Obesity
There is a clear association between dyspnea and
obesity. Obesity increases the work of breathing
because of the reductions in both chest wall
compliance and respiratory muscle strength
• Excess metabolically active adipose tissue plus
↑ workload on supportive respiratory muscle
↑ CO2 production
Hypercarbia
↑ O2 consumption
Hypoxia
35
Respiratory PathophysiologyRespiratory Pathophysiology
in Obesityin Obesity
Obese patient shows
• Restrictive lung disease Pattern
– Decreased chest wall compliance
– Diaphragm forced upwards
– Decreased lung volumes
– Lung volumes decreased by supine and
Trendelenberg positions
– FRC may fall below closing capacity
– Ventilation / Perfusion mismatch
36
Changes in Pulmonary VolumesChanges in Pulmonary Volumes
and Function Testsand Function Tests
• Tidal volume ( TV )
– Normal or Decreased
• Inspiratory reserve volume ( IRV )
– Decreased
• Expiratory reserve volume ( ERV )
– Greatly Decreased
37
Changes in Pulmonary VolumesChanges in Pulmonary Volumes
and Function Testsand Function Tests
• FRC
– Greatly decreased
– Direct inverse relationship between BMI
and FRC
• FEV1
– Normal or slightly decreased
38
Respiratory Pathophysiology
Severe Obese patients are
• Relatively Hypoxemic & Occasionally Hypercapnic
showing
Obesity-hypoventilation Syndrome
(Pickwickian syndrome)
• Obesity usually extreme
• Hypercapnia
• Cyanotic / hypoxemia
• Polycythemia
• Pulmonary HTN
• Biventricular failure
• Somnolence
• Obstructive Sleep Apnea Syndrome (OSAS)
39
OSASOSAS
• Definition
– 10 seconds or more of total cessation of
airflow despite respiratory efforts
• Clinically Relevant
– 5 episodes per hour or 30 episodes per
night
40
OSAS ( clinical )OSAS ( clinical )
• Snoring
• Dry mouth and short arousal during
sleep
• Partners report apnea pauses during
sleep
41
OSASOSAS
• More vulnerable to airway obstruction
– Opioids
– Sedatives
• More vulnerable in supine or
Trendelenberg position
42
Diagnostics Criteria for OSASDiagnostics Criteria for OSAS
Nocturnal Poly-somnography positive
Body Mass Index is more than 30 kg /m2
Daytime PaCo2 is more than 45 mm of Hg
Absence of other known cause of Hypoventilation
43
Respiratory EvaluationRespiratory Evaluation
in Obese Patientin Obese Patient
Ask & Look for,
- Dyspnea, snoring, Chest pain
- Sleep apnea & comfortable sleeping
position
- X-Ray Chest
- Respiratory Rate & Breath Holding time
- Pulmonary Function Test
- Spo2 & EtCo2
44
GI PathophysiologyGI Pathophysiology
∀↑ incidence
– Gastroesophageal reflux
– Hiatal hernia
↑ abdominal pressure
• Severe risk of Aspiration
45
GI PathophysiologyGI Pathophysiology
• After 8 hour Fast
– 85 – 90% of morbidly obese patients
have
• Gastric volumes > 25 ml
• Gastric pH < 2.5
46
Anesthetic ConsiderationsAnesthetic Considerations
↑ risk for aspiration pneumonitis if
reflux history or Acid-Peptic
Disease present
–Consider H2 antagonist ( pre,
intra and post )
–Metoclopramide, Ranitidine or
Ondansetron
47
Over all Assess forOver all Assess for
–Cardio-Pulmonary reserve
–ECG & X-Ray Chest, if
necessary Echocardiography
–LFT & RFT
–ABG
–PFT
–Medication for any Disease
48
PositionPosition
• Proper positioning can be difficultProper positioning can be difficult
• May need extra support under backMay need extra support under back
in Supinein Supine
• POSITION, POSITION, POSITIONPOSITION, POSITION, POSITION
49
15% of obese patients are a difficult intubation
Short thick neck
Obesity and short thick neck Related to OSAS
and to each other
Fat in lateral pharyngeal walls are difficult to
exam in awake patient
PreoperativePreoperative AirwayAirway AssessmentAssessment
for Intubationfor Intubation
50
Preoperative Airway AssessmentPreoperative Airway Assessment
for Intubationfor Intubation
• Limited TM joint mobility
• Limited atlanto-occipital mobility
• Narrow upper airway
• Small space between mandible and sternal fat pads
• See for mallampati classification
• Neck Circumference
51
Best Position for Intubation
External auditory meatus and sternal notch
at same level
52
Class I =
visualization of
the soft palate,
fauces, uvula,
anterior and
posterior pillars.
Class II =
visualization of
the soft palate,
fauces and uvula.
Class III =
visualization of
the soft palate
and the base of
the uvula.
Class IV = soft
palate is not
MallampatMallampati
ClassificationClassification
53
Neck CircumferenceNeck Circumference
• Normal neck circumference is
weight in kg / 2 in cm
• Normal neck cir. at 7o kg is 35 cm
• If it increase by 13 % then difficult
intubation is counted
54
Anesthetic Considerations:Anesthetic Considerations:
PreoperativePreoperative
• BP with appropriate size cuff
if arm is too fatty then forearm or leg
• Plan / examine for Venous / Arterial access
• Preferred to take two secured IV lines
55
Anesthetic Considerations:Anesthetic Considerations:
PreoperativePreoperative
• If HTN – Pre-op good control
• If DM – well controlled
• H/o chest pain then ECG &/or Stress Echo
• Previous anesthesia exposure and any
problem to ask
• If any other related disease then medical
advice
56
Before giving Anaesthesia always keep in mind
• Assistant is always required
• Difficult Mask ventilation & Intubation
• Changes in Cardio-Respiratory System
• High risk of oesophageal reflux (GERD)
• High risk of aspiration
• Rapid sequence intubation with
• pre-oxygenation
• cricoid pressure
• Succinylcholine
• Proper position of Obese patient
57
Induction Airway EquipmentInduction Airway Equipment
• Light Stylet
• Gum elastic bougie
• Oral airway
• LMA’s
• ETT with stylet
58
Anesthetic Considerations:Anesthetic Considerations:
For InductionFor Induction
• Consider awake intubation first or
• Awake fiber optic intubation if difficult airway suspected
– Avoids airway collapse
– Minimal to no sedation
– LMA is good alternative for temporary mechanical
ventilation in grossly and morbid obese patient
– High FIO2
– For Breath sounds ETCO2 important
– Consider tracheotomy kit and surgeon stand by
59
VENTILATIONVENTILATION
• In morbidly obese patients, the best
strategy for ventilation is to deliver TV
according to IBW (10 -12 ml / kg )
• Apply 5 cm H2O PEEP in order to
decrease the incidence of atelectasis.
• Minute ventilation and ETCO2 need to be
monitored closely
• Usually use pressure control ventilation
60
Obesity: PharmacologyObesity: Pharmacology
Overdosing of pre medication and anesthesia
drugs in obese patient is very common
• Doses should be calculated on predicted “lean
body weight”
• Lean body weight = body weight - fat weight
• Avoid IM injection due to unpredictable
absorption
• If possible, avoid narcotics and sedation in
obese patient
61
Obesity: PharmacologyObesity: Pharmacology
• Propofol at TBW
• Thiopental at IBW
• Midazolam at IBW
• Scolene at TBW
• Vcuronium at IBW
• Atracurium at TBW
• Rocuronium at IBW
• Fentanyl & Sufentanyl
at TBW
• Remifentanil at IBW
62
Anesthetic Considerations:Anesthetic Considerations:
IntraoperativeIntraoperative
• Positioning
– 2 OR tables side by side
• If weight is > 350 lbs (150 kg)
– Prone position is poorly tolerated
• Lateral decubitus is keeps abdominal weight off
chest
• Morbidly obese patient should never lie flat
– Semi-Fowler’s position
• Upper body elevated 30 – 400
– Reverse Trendelenburg Position
Best position during post-operative period
63
ReverseReverse Trendelenburg PositionTrendelenburg Position
• RTP is best
intraoperative position
– Can ameliorate
deleterious effects
of supine position
• RTP is 30 degree head
up position
• RTP
↑ pulmonary
compliance
↑ FRC
– Returned P(A-a)O2
to baseline
• RTP may be a better
solution than
– Large TV and PEEP Reverse Trendelenburg
Position
64
MonitoringMonitoring
• ECG
• Pulse Oxymeter
• Blood pressure
• Temperature
• Inspired oxygen concentration
• Capnography
• Arterial catheter to continuously measure BP
and blood gases ( if medically indicated )
• CVP catheter
• Urinary catheter
• Advance monitoring according to Surgery
• If indicated then BIS ( BI-Spectral Index )
65
A – Anesthesia
personnel
M – Machine / Monitor
D – Drug Cart
I – Infusion
V- Ventilator
OT Table
66
Goals for Maintenance of
Anesthesia
• Strict maintenance of airway
• Adequate skeletal muscle relaxation
• Optimum oxygenation
• Maintenance of anesthesia with inhalation and
intravenous agents
• Avoid residual effects of muscle relaxants
• Appropriate intraoperative and postoperative tidal
volume
• Effective postoperative analgesia.
67
Anesthetic Considerations:Anesthetic Considerations:
PostoperativePostoperative
• Respiratory failure risk increased by
– Preoperative hypoxia
– Thoracic or upper abdominal surgery
– Vertical incision
– Delayed extubation
– In complete reversal of muscle relaxation
– Co existing disease
– Un attention of patient
– Narcotics and Sedation
68
Anesthetic Considerations:Anesthetic Considerations:
PostoperativePostoperative
Strictly Followed
• Supplemental O2 after extubation till
Transport from OR to Recovery room & then after
• 45 degree head up position
– Unload diaphragm
– Improves oxygenation
– Improves ventilation
– CPAP and BiPAP should available
69
Always keep in mindAlways keep in mind
• Increased mortality because of post op Hypoxia
– 6.6% vs. 2.7% in non-obese
• Absolute no sedation post op
• Strict Antibiotic &/or Heparin regime Pre &
Post for
– Wound infection
– DVT ( Deep Vein Thrombosis )
– PE ( Pulmonary Embolism )
70
Postoperative Pain ReliefPostoperative Pain Relief
• PCA ( Patient Controlled Analgesia )
– Can provide good pain relief
– Dose based on IBW
• NSAIDs, Local anesthetic infiltration
• Epidural route is preferred for
– Administration of smaller dose than IV
route
71
Obesity & Regional AnesthesiaObesity & Regional Anesthesia
• Regional anesthesia
– Technically more difficult, Long spinal needle
required
– Require 20 – 25% less Local Anesthetic Drugs for
Spinal or Epidural anesthesia because of
• (Epidural fat and distended epidural veins)
• Combined Epidural / General (GA) preferred to
decrease GA requirement
• Epidural anesthesia ↓ postoperative respiratory
complications
72
Airway Management of the Obese (ASA
Guidelines)
• Formulate an airway management plan
• Facial anatomy needs appropriate mask selection
• Increased mass of soft tissues and Macroglossia
• Weight of head
• Head Tilt & "Sniffing Position" may require building up
towels or blankets under the back, scapulae, and shoulders,
as well as the head and neck
• beware of "can’t ventilate, can’t intubate" situations!
• Mask ventilation may require two persons: one to use two-
handed mask technique with triple airway maneuver, airway
device, and CPAP; with another to bag the patient and
monitor effectiveness
• appropriately sized oropharyngeal or nasopharyngeal
airway
• "Bull Neck" – short, thick neck inhibits mobility and makes
visualization of the larynx difficult during laryngoscopy.
• Have "rescue" alternative airway devices ready to hand: e.g.,
Laryngeal Mask Airway (LMA) or Intubating LMA
(Fastrach™); Elastic Gum Bougie; Lighted Stylet;
Esophageal Combi-Tube™; Fiber-optic Laryngoscope or
Bronchoscope
73
Airway Management of the Obese (ASA
Guidelines)
• The first intubation attempt should be by the most
experienced intubator
• If the first best attempt determines difficult or impossible
laryngoscopy or intubation, change to either Rescue Airway
plan (if patient condition is critical), or early Fiberoptic
Intubation before airway trauma worsens the situation
• Large breasts may get in the way of the laryngoscope
handle (half-size handles are available).
• Response to induction agents is less predictable for
intubation
• Confirmation of endotracheal intubation should be by three
or more methods including either capnometry or
capnography
• Obese patients will desaturate oxygen rapidly
• All obese patients with airway problems or impending
intubation should have 100% oxygen
• In failed Intubation by all methods, in emergency
Percutaneous cricothyrotomy or surgical tracheostomy
74
A pre-anesthesia evaluation
-By an anesthesia clinician at least 1 day before
- When possible, within 1 month of scheduled surgery
Minimum labs:
-Hematocrit
-Glucose
-Creatinine and Blood urea
Extended preoperative testing
-As indicated by co morbidities
-According to the American Society of
Anesthesiologists (ASA)
Standard clinical preoperative assessment
-For sleep apnea of every obese surgical patient-
Polysomnography in selected patients.
CONCLUSIONCONCLUSION
75
Smoking cessation
-At least 6 weeks before surgery,
Standard use of the 30° Reverse
Trendelenburg (head up) position
-During preoxygenation, induction,
and emergence from anesthesia.
Induction techniques
to facilitate expeditious tracheal
intubation, which may include a
"rapid sequence induction."
76
Immediate availability of difficult airway
management devices
-Fiber-Optic laryngoscope
-Laryngeal mask airway
An additional anesthesia clinician
-The good OT assistant and the Surgeon
during induction and emergence.
Prior to extubation
-The patient should be fully awake
-Complete reversal of neuromuscular
Tailoring of the anesthetic
-Drugs to promote early return of the
patient’s protective airway reflexes &
Maintenance of oxygenation.
77
Maintaining euvolemia
-Monitoring body temperature, and fluid therapy
The use of alternate sites for noninvasive BP
assessment
_
the forearm or leg if needed
-invasive hemodynamic monitoring as medically
indicated.
For Medications
-Begin dosing closer to the patient’s estimated
lean body mass, TWB and IBW
Use of ASA Standards for Postoperative Care
Taking the implications of a diagnosis of sleep
apnea into consideration
-As well as the patient’s overall medical
condition.
78
Availability of CPAP/BiPAP,
-As needed, postoperatively for
noninvasive positive pressure ventilation.
Post Operative good pain relief
-A combination of local anesthetics with
opioids, Nsaids and possibly epinephrine
in the epidural solution
79
Effective and unimpaired
-Intraoperative and perioperative
communication among the anesthesia,
nursing, and surgical members.
Identification of an anesthesiologist
-With a special interest in anesthetic care
and pain management for obese surgical
patients
Availability of at least
-One portable storage unit with specialized
equipment for management of difficult
airways throughout the perioperative
period, maintained and operated by
clinicians.
80
Availability of a Clinician
-With airway management skills
perioperatively.
Formulation of, and adherence to,
institutional protocols
-Of continued close monitoring of patients
with documented or suspected complications
for perioperative care of patients
81
Case study of female obese patient posted
for Umbilical Hernia Repair
• 55 year old female
• Height 5’2” ( 1.55 meter )
• Weight 114 kg
• BMI 47.5
• ASA Physical Status II
• BP 142/82 mm hg & Resting pulse 82 / mn
• Spo2 at room air 93 %
• Mild asthma
• EF > 50
• No other positive personal, past or family history
• ECG and X-ray chest were normal
• Lab investigations WNL
• Negative history of GERD, snoring and obstructive sleep apnea
• ASA III
82
On Examination
• Very obese patient
• Very short neck
• Mallampati class II airway
• Patient was needing two pillows in supine
• Two anesthetist were there
• Two IV line taken with 20 # veinflon
• Neck circumference 68 cm
83
Preparation
• Pre oxygenation started with 5 liter
through nasal prongs
• Multi parameter (NK) put including Spo2,
ECG, Large BP cuff (NIBP), Temperature
probe
• Patient put supine 30 degree RTP
position with 2 pillows under head
• One nebulizer puff of bronchodilator given
84
Premedication
• Glycopyrolate 1 ml IV
• Rantac 2 ml IV
• Emeset 4 ml
• Lyceft 2 gm IV
• Fentanyl 100 mcg IV
• Midazolam 2 mg IV
• Voveran 3ml IV
diluted
• Xylocard 5 ml IV
85
INDUCTION
• Propofol 1.5 mg / kg IV slowly with total 17
ml given
• Immediately put large size oro pharyngeal
airway
• Cricoid pressure applied
• Spontaneous ventilation maintained and
assisted prior to intubation
86
Intubation
• Cricoid pressure applied
• Scolene 150 mg given fast IV
• Laryngoscopy and Intubation with 7 # cuff
ET with stylet were performed uneventfully
• Cuff pressure 7 ml applied with air
• Not much threatening changes were noted
on multi Para monitor
87
Maintenance
• Patient put on max ventilator with TV 900 ml ( 8
ml/kg) and RR 16 / min
• Capnograpgy put between ET and Ventilator
• Atracurium 50 mg IV bolus
• Oxygen 3 lit and Nitrous Oxide 3 lit with
Isoflurane 2 mark Continuously given
• Atracurium repeated 15 mg around every 30
minutes
• No adverse cardiac or respiratory events
occurred
• Total 1500 ml RL given intra operative
88
At the end
• Nitrous Oxide and Isoflurane discontinued
and Oxygen 100 % around 5 lit continued
• Neuromuscular blockade reversed with
neostigmine 5 mg IV and Glycopyrrolate 1
mg IV
• Mechanical ventilation discontinued upon
resumption of spontaneous ventilation
89
Recovery
• Patient opened eyes and responded to
command approximately 5 minutes after
reversal. No coughing or breath holding noted
• Spontaneous ventilation, with sustained head lift
and oxygen saturation maintained > 95 %
• Extubation performed uneventfully
• Patient transferred to recovery ward in left lateral
position with oxygen 3 lit via nasal route
• Total surgical time was 1 hour 25 minutes and
total anesthesia time was 1 hour 40 minutes
90
Transfer
• Patient put 30 degree head up in recovery
room
• Patient transferred from recovery to
special room after 6 hours
• No major or life threatening changes in
vitals noted in post op period
• Patient discharged after 8 days
91
Message
• The anesthetic management of the clinically
severe obese patient requires meticulous
preoperative, perioperative and postoperative
care.
• Careful planning is essential before taking the
patient in the operating room.
• To have excellent outcome, a multidisciplinary
approach, including the primary care physician,
anesthesiologist, surgeon, nursing staff and
social worker is necessary.
92
93
94
95
96

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Bariatric Anaesthesia - Anesthesia Considerations for Obese Patients

  • 1. 1 BARIATRIC ANAESTHESIABARIATRIC ANAESTHESIA (Anesthesia in Obese Patient(Anesthesia in Obese Patient )) Dr. Tushar ChokshiDr. Tushar Chokshi
  • 2. 2 Two Worst enemy of AnesthetistTwo Worst enemy of Anesthetist OBESITY COPD
  • 3. 3
  • 4. 4 The heaviest person in medical history was Jon Brower Minnoch (USA 1941– 83) 635 kg635 kg
  • 5. 5
  • 6. 6
  • 7. 7 Obesity: DefinitionObesity: Definition • A condition in which excess body fat may put a person at health risk. (laymen) • A chronic metabolic disorder that is primarily induced and sustained by an over consumption or underutilization of caloric substrate (Medical) • The American Heart Association (AHA) defines obesity as body weight 30 percent greater than the ideal body weight (Precise)
  • 8. 8 EquationsEquations • Ideal body weight in Kg (IBW) (Broca’s Index) – Height in centimeters − 100 for men – Height in centimeters − 105 for women – ----------------------------------------------------- • Body mass index (BMI) – weight in Kg / Height (m) 2
  • 9. 9
  • 10. 10 WHO DefinitionsWHO Definitions Obese 20% > IBW BMI > 28 – 35 Morbidly Obese > 2 x IBW BMI > 35
  • 11. 11 Obesity ClassificationObesity Classification Overweight - BMI > 25 kg/m2 Obesity - BMI > 30 kg/m2 Morbid Obesity - BMI > 40 kg/m2 or 35 with coexisting co morbidities Super Obese Patient - BMI > 50 kg/m2
  • 12. 12 My own BMIMy own BMI • My weight is 80 kg • My height is 5’8” (170 cm or 1.7 meter) • So my BMI 82 / (1.7)2 is 27.68 • So I am Overweight but not obese
  • 13. 13 Obesity-- Disease –Death RiskObesity-- Disease –Death Risk BMI( kg / m2 ) Class Hazard Ratio for All Cause Death Disease Risk 18.5 – 24.9 Normal 1 % --- 25 – 29.9 Overweight 1.16 % Increased 30 – 34.9 Obesity I 1.25 % High 35 – 39.9 Obesity II 2.96 % Very High > 40 Obesity III 2.96 % Extremely High
  • 14. 14 Height (ft'in") 5'0" 5'2" 5'4" 5'6" 5'8" 5'10" 6'0" 6'2" 6'4" 6'6" Height (in) 60 62 64 66 68 70 72 74 76 78 BMI (kg/m2) 150 29.4 27.5 25.8 24.3 22.9 21.6 20.4 19.3 18.3 17.4 160 31.3 29.3 27.5 25.9 24.4 23.0 21.7 20.6 19.5 18.5 170 33.3 31.2 29.2 27.5 25.9 24.4 23.1 21.9 20.7 19.7 180 35.2 33.0 31.0 29.1 27.4 25.9 24.5 23.2 22.0 20.8 190 37.2 34.8 32.7 30.7 28.9 27.3 25.8 24.4 23.2 22.0 200 39.1 36.7 34.4 32.3 30.5 28.8 27.2 25.7 24.4 23.2 210 41.1 38.5 36.1 34.0 32.0 30.2 28.5 27.0 25.6 24.3 220 43.1 40.3 37.8 35.6 33.5 31.6 29.9 28.3 26.8 25.5 230 45.0 42.2 39.6 37.2 35.0 33.1 31.3 29.6 28.1 26.6 240 47.0 44.0 41.3 38.8 36.6 34.5 32.6 30.9 29.3 27.8 250 48.9 45.8 43.0 40.4 38.1 35.9 34.0 32.2 30.5 29.0 260 50.9 47.7 44.7 42.1 39.6 37.4 35.3 33.5 31.7 30.1 270 52.8 49.5 46.4 43.7 41.1 38.8 36.7 34.7 32.9 31.3 280 54.8 51.3 48.2 45.3 42.7 40.3 38.1 36.0 34.2 32.4 290 56.8 53.2 49.9 46.9 44.2 41.7 39.4 37.3 35.4 33.6 300 58.7 55.0 51.6 48.5 45.7 43.1 40.8 38.6 36.6 34.7 310 60.7 56.8 53.3 50.1 47.2 44.6 42.1 39.9 37.8 35.9 320 62.6 58.7 55.0 51.8 48.8 46.0 43.5 41.2 39.0 37.1 330 64.6 60.5 56.8 53.4 50.3 47.4 44.8 42.5 40.3 38.2 340 66.5 62.3 58.5 55.0 51.8 48.9 46.2 43.7 41.5 39.4 350 68.5 64.1 60.2 56.6 53.3 50.3 47.6 45.0 42.7 40.5 360 70.5 66.0 61.9 58.2 54.9 51.8 48.9 46.3 43.9 41.7 370 72.4 67.8 63.6 59.8 56.4 53.2 50.3 47.6 45.1 42.8 380 74.4 69.6 65.4 61.5 57.9 54.6 51.6 48.9 46.4 44.0 390 76.3 71.5 67.1 63.1 59.4 56.1 53.0 50.2 47.6 45.2 400 78.3 73.3 68.8 64.7 60.9 57.5 54.4 51.5 48.8 46.3 410 80.2 75.1 70.5 66.3 62.5 59.0 55.7 52.8 50.0 47.5 Morbidly Obese Overweigh Obese
  • 15. 15 Incidence of ObesityIncidence of Obesity • 23 % are obese of world population • 5% are morbidly obese • Mortality is 2.96 times higher in obese
  • 16. 16 Twenty Years of Increasing Obesity 30.5% 22.9% 15%14.5%13.4% 0% 10% 20% 30% 40% 1960 1974 1980 1994 2000 %Obesity Source NCHS -- JAMA 2002:14:1723-27.
  • 17. 17 Causes of ObesityCauses of Obesity – Genetic predisposition – Socialization – Age – Sex – Race – Economic status – Psychological ( Dietary Habits ) – Cultural – Emotional – Environmental factors – Cessation of smoking
  • 18. 18 Diseases Linked to ObesityDiseases Linked to Obesity • Diabetes • Coronary Heart Disease • High Blood Pressure • Stroke • Arthritis • Gastroesophageal reflux • Cancer • High cholesterol • Endocrine disease
  • 19. 19 Diseases Linked to ObesityDiseases Linked to Obesity • Hypertrophic Cardiomyopathy • Infertility • Depression • Obstructive sleep apnea • Gallstones • Fatty liver • Stress incontinence • Venous ulcers • End-stage kidney failure • Sudden death
  • 20. 20 A 10-kg higher body weight is associated with a 3.0-mm Hg higher systolic and a 2.3-mm Hg higher diastolic blood pressure. These increases translate into an estimated 12% increased risk for CHD and 24% increased risk for stroke Hypertension is about 6 times more frequent in obese subjects than in lean men and women
  • 21. 21 Physical Complications of ObesityPhysical Complications of Obesity • Heart disease • Type II diabetes mellitus • Hypertension • Stroke • Cancer (endometrial, breast, prostrate, colon) • Gallbladder disease • Sleep apnea • Osteoarthritis • Reduced fertility • increased risk of morbidity and mortality as well as reduced life expectancy • Psychological & Sexual
  • 22. 22 Psychological ComplicationsPsychological Complications of Obesityof Obesity • Emotional distress • Discrimination • Social stigmatization • Anxiety, fear, hostility and insecurity
  • 23. 23 Diabetes Mellitus Type 2Diabetes Mellitus Type 2 prevalence isprevalence is 2.9 times higher in the obese than in non-2.9 times higher in the obese than in non- obese for those 20-75 years of age.obese for those 20-75 years of age. Morbidity due toMorbidity due to Cardio-vascularCardio-vascular diseasesdiseases has been reported to be almosthas been reported to be almost 90 % in those with severe obesity.90 % in those with severe obesity.
  • 25. 25 Changes in Body system due to Obesity • Cardiovascular Physiology • Respiratory Physiology • Gastro Physiology
  • 26. 26 Cardiovascular PathophysiologyCardiovascular Pathophysiology in Obesityin Obesity • Excess body mass leads ↑ metabolic demand → ↑ Cardiac Output For every 13.5 kg of fat gained: – 25 miles of neovascularization occurs – Increased CO of 0.1 L/min for each kg of fat. ↑ workload • LVH ∀↑ Pulmonary blood flow – Pulmonary HTN → Cor Pulmonale → Right Heart Failure ∀ ↑ SV and SW Proportion to body weight LVH dilatation
  • 27. 27 Cardiovascular PathophysiologyCardiovascular Pathophysiology • --↑ Risk of arrhythmias – Hypertrophy of Myocardium – Hypoxemia – Fatty infiltration of cardiac conduction system ↑ Catecholamines – Sleep apnea – Dyslipidemia – Glucose intolerance
  • 28. 28 Cardiac Evaluation:Cardiac Evaluation: in obese patientin obese patient Ask for • Prior MI ( Myocardial Ischemia / Infraction ) • HTN ( Hypertension ) • Angina • PVD ( Peripheral Vascular Disease ) • Limitations in exercise tolerance • History of orthopnea • Paroxysmal nocturnal dyspnea
  • 29. 29 In ECG look forIn ECG look for – Resting rate – Rhythm – Ventricular hypertrophy or strain – Ischemic changes or evidence of Coronary Artery Disease – Low voltage ECG – Axis deviation and atrial tachyarrhythmias – LVH – Ventricular ectopy
  • 30. 30 ECG Changes That May Occur in Obese IndividualsECG Changes That May Occur in Obese Individuals Heart rate PR interval QRS interval or QRS voltage QTc interval QT dispersion T Inversion ST-T abnormalities ST depression Left-axis deviation Flattening of the T wave (inferolateral leads) Left atrial abnormalities False-positive criteria for inferior myocardial infarction
  • 31. 31 Vascular Access in obeseVascular Access in obese Very Challenging – Excessive fat obscures blood vessels – Always put IV cannula ( No Scalp Veins ) – Central line placement, if indicated
  • 32. 32 Volume Replacement in ObeseVolume Replacement in Obese • Adult total body water percentage is 70 % in normal individual But • Severely obese has total body water is 40%. And • In obese patient estimated blood volume is 50 ml / kg, then 70 ml / kg in non-obese So, Obese patient less tolerate fluid & blood loss during surgery
  • 33. 33 Volume ReplacementVolume Replacement • Avoid rapid rehydration, to – Lessen cardiopulmonary compromise. • Administer Hetastarch at recommended volumes per kilogram of IBW – 20 mL/kg • Albumin 5% and 25% used as indicated – To Support circulatory volume and oncotic pressure. • Replace blood loss with crystalloid – 3:1 ratio
  • 34. 34 Respiratory PathophysiologyRespiratory Pathophysiology in Obesityin Obesity There is a clear association between dyspnea and obesity. Obesity increases the work of breathing because of the reductions in both chest wall compliance and respiratory muscle strength • Excess metabolically active adipose tissue plus ↑ workload on supportive respiratory muscle ↑ CO2 production Hypercarbia ↑ O2 consumption Hypoxia
  • 35. 35 Respiratory PathophysiologyRespiratory Pathophysiology in Obesityin Obesity Obese patient shows • Restrictive lung disease Pattern – Decreased chest wall compliance – Diaphragm forced upwards – Decreased lung volumes – Lung volumes decreased by supine and Trendelenberg positions – FRC may fall below closing capacity – Ventilation / Perfusion mismatch
  • 36. 36 Changes in Pulmonary VolumesChanges in Pulmonary Volumes and Function Testsand Function Tests • Tidal volume ( TV ) – Normal or Decreased • Inspiratory reserve volume ( IRV ) – Decreased • Expiratory reserve volume ( ERV ) – Greatly Decreased
  • 37. 37 Changes in Pulmonary VolumesChanges in Pulmonary Volumes and Function Testsand Function Tests • FRC – Greatly decreased – Direct inverse relationship between BMI and FRC • FEV1 – Normal or slightly decreased
  • 38. 38 Respiratory Pathophysiology Severe Obese patients are • Relatively Hypoxemic & Occasionally Hypercapnic showing Obesity-hypoventilation Syndrome (Pickwickian syndrome) • Obesity usually extreme • Hypercapnia • Cyanotic / hypoxemia • Polycythemia • Pulmonary HTN • Biventricular failure • Somnolence • Obstructive Sleep Apnea Syndrome (OSAS)
  • 39. 39 OSASOSAS • Definition – 10 seconds or more of total cessation of airflow despite respiratory efforts • Clinically Relevant – 5 episodes per hour or 30 episodes per night
  • 40. 40 OSAS ( clinical )OSAS ( clinical ) • Snoring • Dry mouth and short arousal during sleep • Partners report apnea pauses during sleep
  • 41. 41 OSASOSAS • More vulnerable to airway obstruction – Opioids – Sedatives • More vulnerable in supine or Trendelenberg position
  • 42. 42 Diagnostics Criteria for OSASDiagnostics Criteria for OSAS Nocturnal Poly-somnography positive Body Mass Index is more than 30 kg /m2 Daytime PaCo2 is more than 45 mm of Hg Absence of other known cause of Hypoventilation
  • 43. 43 Respiratory EvaluationRespiratory Evaluation in Obese Patientin Obese Patient Ask & Look for, - Dyspnea, snoring, Chest pain - Sleep apnea & comfortable sleeping position - X-Ray Chest - Respiratory Rate & Breath Holding time - Pulmonary Function Test - Spo2 & EtCo2
  • 44. 44 GI PathophysiologyGI Pathophysiology ∀↑ incidence – Gastroesophageal reflux – Hiatal hernia ↑ abdominal pressure • Severe risk of Aspiration
  • 45. 45 GI PathophysiologyGI Pathophysiology • After 8 hour Fast – 85 – 90% of morbidly obese patients have • Gastric volumes > 25 ml • Gastric pH < 2.5
  • 46. 46 Anesthetic ConsiderationsAnesthetic Considerations ↑ risk for aspiration pneumonitis if reflux history or Acid-Peptic Disease present –Consider H2 antagonist ( pre, intra and post ) –Metoclopramide, Ranitidine or Ondansetron
  • 47. 47 Over all Assess forOver all Assess for –Cardio-Pulmonary reserve –ECG & X-Ray Chest, if necessary Echocardiography –LFT & RFT –ABG –PFT –Medication for any Disease
  • 48. 48 PositionPosition • Proper positioning can be difficultProper positioning can be difficult • May need extra support under backMay need extra support under back in Supinein Supine • POSITION, POSITION, POSITIONPOSITION, POSITION, POSITION
  • 49. 49 15% of obese patients are a difficult intubation Short thick neck Obesity and short thick neck Related to OSAS and to each other Fat in lateral pharyngeal walls are difficult to exam in awake patient PreoperativePreoperative AirwayAirway AssessmentAssessment for Intubationfor Intubation
  • 50. 50 Preoperative Airway AssessmentPreoperative Airway Assessment for Intubationfor Intubation • Limited TM joint mobility • Limited atlanto-occipital mobility • Narrow upper airway • Small space between mandible and sternal fat pads • See for mallampati classification • Neck Circumference
  • 51. 51 Best Position for Intubation External auditory meatus and sternal notch at same level
  • 52. 52 Class I = visualization of the soft palate, fauces, uvula, anterior and posterior pillars. Class II = visualization of the soft palate, fauces and uvula. Class III = visualization of the soft palate and the base of the uvula. Class IV = soft palate is not MallampatMallampati ClassificationClassification
  • 53. 53 Neck CircumferenceNeck Circumference • Normal neck circumference is weight in kg / 2 in cm • Normal neck cir. at 7o kg is 35 cm • If it increase by 13 % then difficult intubation is counted
  • 54. 54 Anesthetic Considerations:Anesthetic Considerations: PreoperativePreoperative • BP with appropriate size cuff if arm is too fatty then forearm or leg • Plan / examine for Venous / Arterial access • Preferred to take two secured IV lines
  • 55. 55 Anesthetic Considerations:Anesthetic Considerations: PreoperativePreoperative • If HTN – Pre-op good control • If DM – well controlled • H/o chest pain then ECG &/or Stress Echo • Previous anesthesia exposure and any problem to ask • If any other related disease then medical advice
  • 56. 56 Before giving Anaesthesia always keep in mind • Assistant is always required • Difficult Mask ventilation & Intubation • Changes in Cardio-Respiratory System • High risk of oesophageal reflux (GERD) • High risk of aspiration • Rapid sequence intubation with • pre-oxygenation • cricoid pressure • Succinylcholine • Proper position of Obese patient
  • 57. 57 Induction Airway EquipmentInduction Airway Equipment • Light Stylet • Gum elastic bougie • Oral airway • LMA’s • ETT with stylet
  • 58. 58 Anesthetic Considerations:Anesthetic Considerations: For InductionFor Induction • Consider awake intubation first or • Awake fiber optic intubation if difficult airway suspected – Avoids airway collapse – Minimal to no sedation – LMA is good alternative for temporary mechanical ventilation in grossly and morbid obese patient – High FIO2 – For Breath sounds ETCO2 important – Consider tracheotomy kit and surgeon stand by
  • 59. 59 VENTILATIONVENTILATION • In morbidly obese patients, the best strategy for ventilation is to deliver TV according to IBW (10 -12 ml / kg ) • Apply 5 cm H2O PEEP in order to decrease the incidence of atelectasis. • Minute ventilation and ETCO2 need to be monitored closely • Usually use pressure control ventilation
  • 60. 60 Obesity: PharmacologyObesity: Pharmacology Overdosing of pre medication and anesthesia drugs in obese patient is very common • Doses should be calculated on predicted “lean body weight” • Lean body weight = body weight - fat weight • Avoid IM injection due to unpredictable absorption • If possible, avoid narcotics and sedation in obese patient
  • 61. 61 Obesity: PharmacologyObesity: Pharmacology • Propofol at TBW • Thiopental at IBW • Midazolam at IBW • Scolene at TBW • Vcuronium at IBW • Atracurium at TBW • Rocuronium at IBW • Fentanyl & Sufentanyl at TBW • Remifentanil at IBW
  • 62. 62 Anesthetic Considerations:Anesthetic Considerations: IntraoperativeIntraoperative • Positioning – 2 OR tables side by side • If weight is > 350 lbs (150 kg) – Prone position is poorly tolerated • Lateral decubitus is keeps abdominal weight off chest • Morbidly obese patient should never lie flat – Semi-Fowler’s position • Upper body elevated 30 – 400 – Reverse Trendelenburg Position Best position during post-operative period
  • 63. 63 ReverseReverse Trendelenburg PositionTrendelenburg Position • RTP is best intraoperative position – Can ameliorate deleterious effects of supine position • RTP is 30 degree head up position • RTP ↑ pulmonary compliance ↑ FRC – Returned P(A-a)O2 to baseline • RTP may be a better solution than – Large TV and PEEP Reverse Trendelenburg Position
  • 64. 64 MonitoringMonitoring • ECG • Pulse Oxymeter • Blood pressure • Temperature • Inspired oxygen concentration • Capnography • Arterial catheter to continuously measure BP and blood gases ( if medically indicated ) • CVP catheter • Urinary catheter • Advance monitoring according to Surgery • If indicated then BIS ( BI-Spectral Index )
  • 65. 65 A – Anesthesia personnel M – Machine / Monitor D – Drug Cart I – Infusion V- Ventilator OT Table
  • 66. 66 Goals for Maintenance of Anesthesia • Strict maintenance of airway • Adequate skeletal muscle relaxation • Optimum oxygenation • Maintenance of anesthesia with inhalation and intravenous agents • Avoid residual effects of muscle relaxants • Appropriate intraoperative and postoperative tidal volume • Effective postoperative analgesia.
  • 67. 67 Anesthetic Considerations:Anesthetic Considerations: PostoperativePostoperative • Respiratory failure risk increased by – Preoperative hypoxia – Thoracic or upper abdominal surgery – Vertical incision – Delayed extubation – In complete reversal of muscle relaxation – Co existing disease – Un attention of patient – Narcotics and Sedation
  • 68. 68 Anesthetic Considerations:Anesthetic Considerations: PostoperativePostoperative Strictly Followed • Supplemental O2 after extubation till Transport from OR to Recovery room & then after • 45 degree head up position – Unload diaphragm – Improves oxygenation – Improves ventilation – CPAP and BiPAP should available
  • 69. 69 Always keep in mindAlways keep in mind • Increased mortality because of post op Hypoxia – 6.6% vs. 2.7% in non-obese • Absolute no sedation post op • Strict Antibiotic &/or Heparin regime Pre & Post for – Wound infection – DVT ( Deep Vein Thrombosis ) – PE ( Pulmonary Embolism )
  • 70. 70 Postoperative Pain ReliefPostoperative Pain Relief • PCA ( Patient Controlled Analgesia ) – Can provide good pain relief – Dose based on IBW • NSAIDs, Local anesthetic infiltration • Epidural route is preferred for – Administration of smaller dose than IV route
  • 71. 71 Obesity & Regional AnesthesiaObesity & Regional Anesthesia • Regional anesthesia – Technically more difficult, Long spinal needle required – Require 20 – 25% less Local Anesthetic Drugs for Spinal or Epidural anesthesia because of • (Epidural fat and distended epidural veins) • Combined Epidural / General (GA) preferred to decrease GA requirement • Epidural anesthesia ↓ postoperative respiratory complications
  • 72. 72 Airway Management of the Obese (ASA Guidelines) • Formulate an airway management plan • Facial anatomy needs appropriate mask selection • Increased mass of soft tissues and Macroglossia • Weight of head • Head Tilt & "Sniffing Position" may require building up towels or blankets under the back, scapulae, and shoulders, as well as the head and neck • beware of "can’t ventilate, can’t intubate" situations! • Mask ventilation may require two persons: one to use two- handed mask technique with triple airway maneuver, airway device, and CPAP; with another to bag the patient and monitor effectiveness • appropriately sized oropharyngeal or nasopharyngeal airway • "Bull Neck" – short, thick neck inhibits mobility and makes visualization of the larynx difficult during laryngoscopy. • Have "rescue" alternative airway devices ready to hand: e.g., Laryngeal Mask Airway (LMA) or Intubating LMA (Fastrach™); Elastic Gum Bougie; Lighted Stylet; Esophageal Combi-Tube™; Fiber-optic Laryngoscope or Bronchoscope
  • 73. 73 Airway Management of the Obese (ASA Guidelines) • The first intubation attempt should be by the most experienced intubator • If the first best attempt determines difficult or impossible laryngoscopy or intubation, change to either Rescue Airway plan (if patient condition is critical), or early Fiberoptic Intubation before airway trauma worsens the situation • Large breasts may get in the way of the laryngoscope handle (half-size handles are available). • Response to induction agents is less predictable for intubation • Confirmation of endotracheal intubation should be by three or more methods including either capnometry or capnography • Obese patients will desaturate oxygen rapidly • All obese patients with airway problems or impending intubation should have 100% oxygen • In failed Intubation by all methods, in emergency Percutaneous cricothyrotomy or surgical tracheostomy
  • 74. 74 A pre-anesthesia evaluation -By an anesthesia clinician at least 1 day before - When possible, within 1 month of scheduled surgery Minimum labs: -Hematocrit -Glucose -Creatinine and Blood urea Extended preoperative testing -As indicated by co morbidities -According to the American Society of Anesthesiologists (ASA) Standard clinical preoperative assessment -For sleep apnea of every obese surgical patient- Polysomnography in selected patients. CONCLUSIONCONCLUSION
  • 75. 75 Smoking cessation -At least 6 weeks before surgery, Standard use of the 30° Reverse Trendelenburg (head up) position -During preoxygenation, induction, and emergence from anesthesia. Induction techniques to facilitate expeditious tracheal intubation, which may include a "rapid sequence induction."
  • 76. 76 Immediate availability of difficult airway management devices -Fiber-Optic laryngoscope -Laryngeal mask airway An additional anesthesia clinician -The good OT assistant and the Surgeon during induction and emergence. Prior to extubation -The patient should be fully awake -Complete reversal of neuromuscular Tailoring of the anesthetic -Drugs to promote early return of the patient’s protective airway reflexes & Maintenance of oxygenation.
  • 77. 77 Maintaining euvolemia -Monitoring body temperature, and fluid therapy The use of alternate sites for noninvasive BP assessment _ the forearm or leg if needed -invasive hemodynamic monitoring as medically indicated. For Medications -Begin dosing closer to the patient’s estimated lean body mass, TWB and IBW Use of ASA Standards for Postoperative Care Taking the implications of a diagnosis of sleep apnea into consideration -As well as the patient’s overall medical condition.
  • 78. 78 Availability of CPAP/BiPAP, -As needed, postoperatively for noninvasive positive pressure ventilation. Post Operative good pain relief -A combination of local anesthetics with opioids, Nsaids and possibly epinephrine in the epidural solution
  • 79. 79 Effective and unimpaired -Intraoperative and perioperative communication among the anesthesia, nursing, and surgical members. Identification of an anesthesiologist -With a special interest in anesthetic care and pain management for obese surgical patients Availability of at least -One portable storage unit with specialized equipment for management of difficult airways throughout the perioperative period, maintained and operated by clinicians.
  • 80. 80 Availability of a Clinician -With airway management skills perioperatively. Formulation of, and adherence to, institutional protocols -Of continued close monitoring of patients with documented or suspected complications for perioperative care of patients
  • 81. 81 Case study of female obese patient posted for Umbilical Hernia Repair • 55 year old female • Height 5’2” ( 1.55 meter ) • Weight 114 kg • BMI 47.5 • ASA Physical Status II • BP 142/82 mm hg & Resting pulse 82 / mn • Spo2 at room air 93 % • Mild asthma • EF > 50 • No other positive personal, past or family history • ECG and X-ray chest were normal • Lab investigations WNL • Negative history of GERD, snoring and obstructive sleep apnea • ASA III
  • 82. 82 On Examination • Very obese patient • Very short neck • Mallampati class II airway • Patient was needing two pillows in supine • Two anesthetist were there • Two IV line taken with 20 # veinflon • Neck circumference 68 cm
  • 83. 83 Preparation • Pre oxygenation started with 5 liter through nasal prongs • Multi parameter (NK) put including Spo2, ECG, Large BP cuff (NIBP), Temperature probe • Patient put supine 30 degree RTP position with 2 pillows under head • One nebulizer puff of bronchodilator given
  • 84. 84 Premedication • Glycopyrolate 1 ml IV • Rantac 2 ml IV • Emeset 4 ml • Lyceft 2 gm IV • Fentanyl 100 mcg IV • Midazolam 2 mg IV • Voveran 3ml IV diluted • Xylocard 5 ml IV
  • 85. 85 INDUCTION • Propofol 1.5 mg / kg IV slowly with total 17 ml given • Immediately put large size oro pharyngeal airway • Cricoid pressure applied • Spontaneous ventilation maintained and assisted prior to intubation
  • 86. 86 Intubation • Cricoid pressure applied • Scolene 150 mg given fast IV • Laryngoscopy and Intubation with 7 # cuff ET with stylet were performed uneventfully • Cuff pressure 7 ml applied with air • Not much threatening changes were noted on multi Para monitor
  • 87. 87 Maintenance • Patient put on max ventilator with TV 900 ml ( 8 ml/kg) and RR 16 / min • Capnograpgy put between ET and Ventilator • Atracurium 50 mg IV bolus • Oxygen 3 lit and Nitrous Oxide 3 lit with Isoflurane 2 mark Continuously given • Atracurium repeated 15 mg around every 30 minutes • No adverse cardiac or respiratory events occurred • Total 1500 ml RL given intra operative
  • 88. 88 At the end • Nitrous Oxide and Isoflurane discontinued and Oxygen 100 % around 5 lit continued • Neuromuscular blockade reversed with neostigmine 5 mg IV and Glycopyrrolate 1 mg IV • Mechanical ventilation discontinued upon resumption of spontaneous ventilation
  • 89. 89 Recovery • Patient opened eyes and responded to command approximately 5 minutes after reversal. No coughing or breath holding noted • Spontaneous ventilation, with sustained head lift and oxygen saturation maintained > 95 % • Extubation performed uneventfully • Patient transferred to recovery ward in left lateral position with oxygen 3 lit via nasal route • Total surgical time was 1 hour 25 minutes and total anesthesia time was 1 hour 40 minutes
  • 90. 90 Transfer • Patient put 30 degree head up in recovery room • Patient transferred from recovery to special room after 6 hours • No major or life threatening changes in vitals noted in post op period • Patient discharged after 8 days
  • 91. 91 Message • The anesthetic management of the clinically severe obese patient requires meticulous preoperative, perioperative and postoperative care. • Careful planning is essential before taking the patient in the operating room. • To have excellent outcome, a multidisciplinary approach, including the primary care physician, anesthesiologist, surgeon, nursing staff and social worker is necessary.
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Editor's Notes

  1. Car
  2. Integration of possible implications of suspected OSA into perioperative care. Smoking cessation at least 6 weeks before surgery, including active support for this approach by the patients’ Standard use of the 30° reverse Trendelenburg (head up) position during preoxygenation, induction, and emergence from anesthesia. Induction techniques to facilitate expeditious tracheal intubation, which may include a &amp;quot;rapid sequence induction.&amp;quot; Integration of possible implications of suspected OSA into perioperative care. Smoking cessation at least 6 weeks before surgery, including active support for this approach by the patients’ Standard use of the 30° reverse Trendelenburg (head up) position during preoxygenation, induction, and emergence from anesthesia. Induction techniques to facilitate expeditious tracheal intubation, which may include a &amp;quot;rapid sequence induction.&amp;quot;
  3. Effective and unimpaired intraoperative and perioperative communication among the anesthesia, nursing, and surgical members. Identification of an anesthesiologist with a special interest in anesthetic care and pain management for obese surgical patients to serve as an interdepartmental liaison to bariatric surgeons. Availability of at least one portable storage unit with specialized equipment for management of difficult airways throughout the perioperative period, maintained and operated by clinicians. Effective and unimpaired intraoperative and perioperative communication among the anesthesia, nursing, and surgical members. Identification of an anesthesiologist with a special interest in anesthetic care and pain management for obese surgical patients to serve as an interdepartmental liaison to bariatric surgeons. Availability of at least one portable storage unit with specialized equipment for management of difficult airways throughout the perioperative period, maintained and operated by clinicians.