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MORBID
By
DR NIKHIL AMEERCHETTY ,MS
• Western world is more affected
• One third of the U.S. adult population is obese
• 300000 annual deaths
• second leading cause of preventable death
• morbidly obese man has a 22% reduction in life expectancy,
DEFINITION
• BMI equal to or greater than 40 kg/m2 without comorbidities
and >35kg/m2 with comorbidities .
National Institutes of Health. Am J Clin Nutr. 1992
HISTORY
• Jejunoileal bypass (JIB), was described in 1954
• Edward Mason devised the vertical banded Gastroplasty in 1960’s
• Nicola Scopinaro biliopancreatic diversion (BPD)
• Marceau duodenal switch non dividing duodenem 1993
• Hess and hess modified it to dividing the duodenum in 1998
• Gagner in 2000 laproscopic bpd-ds
• Fisher text book of surgery 6th edition .
CAUSES
Genetic Predisposition
Eating Disorders
Psychological Issues
Poor Diet
Lack Of Exercise
Comorbid Conditions
Metabolic Syndrome
CO-MORBIDITIES
PATHOPHYSIOLOGY
• Grehlin hormone at fundus – appetite stimulus
• GLP-1, PYY and CCk causes insulin release – reduces apetite
• Trifty genes
• Prentice AM, Natural selection of thrifty genes , Int J Obes (Lond) 2008
RATIONALE FOR SURGERY
• Increase life expectancy
• Decrease comorbidities
• Decrease health-care costs to society
• Swedish Obese Subjects study, which started in 1987
SELECTION CRITERIA
• International Federation for Surgery of Obesity and the National Institute for Clinical Excellence.
• Body mass index (BMI) >40 kg/m2 or BMI 35–39 kg/m2 with comorbid disease
• Minimum of 5 years obesity
• Failure of conservative treatment
• No alcoholism or major untreated psychiatric illness
• Avoid if likely to get pregnant within 2 years
• Age limits 18–55 (relative)
• Acceptable operative risk on preoperative assessment
OBESITY MULTIDISCIPLINARY TEAM (MDT)
PLANNING
• No bariatric operation will produce optimal long-term results without
significant changes in diet, exercise,and lifestyle.
• Low carbohydrate diet for atleast 2 weeks .
• “I will never go back to being the way I was before.”
PER-OPERATIVE ASSESSMENT
• Before the clinical visit
• medically supervised diet
• Initial Clinic Visit
• Group presentation on preoperative and postoperative nutritional issues by the nutritionist
• Individual assessment by the surgeon’s team
• Individual counseling session with the surgeon
• Individual counseling session with the nutritionist
• Screening blood tests
• Subsequent Events and Evaluations
• Screening flexible upper endoscopy
• Screening ultrasound of the gallbladder
• Subsequent Clinic Visits
• Counseling session with the surgeon (including selection of the date for surgery)
• Education session with the nurse educator
• Preoperative evaluation by the anesthesiologist
• Final paperwork by the preadmissions center
SPECIAL EQUIPMENT
• Hydraulically operated table accommodating up to 800 lb.
• Side attachments
• Foam cushioning
• Extra large SCD stockings
• Wide and secure padded straps for
the abdomen and legs
• High-flow insufflators
• Extra-long staplers
• Atraumatic graspers
• Extra-long trocars
• An ultrasonic scalpel
• A fixed retractor device for clamping and holding the liver retractor is also essential.
•MEDICAL TREATMENT
•SURGICAL TREATMENT
MEDICAL TREATMENT
• Diets
• Exercise
• Slimming clubs
• Pharmacological agents.
• 97 per cent long-term failure rate
SURGICAL OPTIONS
• Restrictive
• Vertical banded gastroplasty (VBG)
• Laparoscopic adjustable gastric banding (AGB)
• Laparoscopic sleeve gastrectomy (LSG)
• Largely Restrictive, Mildly Malabsorptive
• Roux-en-Y gastric bypass (RYGB)
• Largely Malabsorptive, Mildly Restrictive
• Biliopancreatic diversion (BPD)
• Duodenal switch (DS)
VERTICAL BAND GASTROPLASTY
• Abandoned
• Poor long-term weight loss
• High rate of late stenosis of the gastric outlet
• Regain of weight
LAPROSCOPIC ADJUSTIBLE GASTRIC
BANDING
• FDA approved LAP-BAND and REALIZE BAND
• Principle : Augment the early satiety, Vagal nerves feedback mechanism
• Advantage : Adjustability and Low morbidity and mortality .
• Ideal method for patients with BMI 35 - 40kg/m²
• 0.1% perioperative mortality rate
• 15mm pneumoperitoneum left upper quadrant, at the midclavicular line, one hand breath
below the xiphoid.
• 12-mm camera port in the midline approximately 15 cm from the xiphoid.
• 5-mm port is placed in the right upper quadrant for the surgeon’s left hand.
• 5-mm port in the left upper quadrant is placed for the assistant
• Port in the epigastrium is placed to assist in retracting the left lobe of the liver
SLEEVE GASTRECTOMY
• 0.2 per cent operative mortality.
• Removes most of the grehlin
• Disadvantage : leakage, sleeve expansion
• 65 per cent weight loss by 2 years
• 10-20% resleeve procedure
ROUX-EN-Y GASTRIC BYPASS
• 65–75 per cent excess weight loss
• Risk 0.5 per cent
• Uses : GERD or type 2 diabetes.
• Limitation : Decreases Iron absorption .
• Theories : Foregut and Hind gut theory
proposed for weight loss
BILIOPANCREATIC DIVERSION – WITH OR
WITHOUT
A DUODENAL SWITCH
• 75–85 per cent excess
• Mortality of 1–2 per cent
• Extreme malabsorption
Biliopancreatic diversion
Biliopancreatic diversion with
duodenal switch
RESULTS
• How to define success?
• Losing at least 50 per cent of the excess weight in the first 12–24 months.
• Decrease comorbidities
• Improved quality of life .
COMPARATIVE CHART
EMERGING TRENDS
• Neuromodulation using
• Gastric-implanted electrodes
• Vagal blocking using electrodes around the abdominal vagus,
• Endoscopically placed intraluminal sleeves
• Endoscopic gastric restriction
• Single incision and transvaginal approaches.
BEFORE AND AFTER VERTICAL SLEEVE GASTRECTOMY
• Mini gastric bypass
Morbid obesity and various treatment options

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Morbid obesity and various treatment options

  • 2. • Western world is more affected • One third of the U.S. adult population is obese • 300000 annual deaths • second leading cause of preventable death • morbidly obese man has a 22% reduction in life expectancy,
  • 3. DEFINITION • BMI equal to or greater than 40 kg/m2 without comorbidities and >35kg/m2 with comorbidities . National Institutes of Health. Am J Clin Nutr. 1992
  • 4. HISTORY • Jejunoileal bypass (JIB), was described in 1954 • Edward Mason devised the vertical banded Gastroplasty in 1960’s • Nicola Scopinaro biliopancreatic diversion (BPD) • Marceau duodenal switch non dividing duodenem 1993 • Hess and hess modified it to dividing the duodenum in 1998 • Gagner in 2000 laproscopic bpd-ds • Fisher text book of surgery 6th edition .
  • 5. CAUSES Genetic Predisposition Eating Disorders Psychological Issues Poor Diet Lack Of Exercise Comorbid Conditions Metabolic Syndrome
  • 7. PATHOPHYSIOLOGY • Grehlin hormone at fundus – appetite stimulus • GLP-1, PYY and CCk causes insulin release – reduces apetite • Trifty genes • Prentice AM, Natural selection of thrifty genes , Int J Obes (Lond) 2008
  • 8. RATIONALE FOR SURGERY • Increase life expectancy • Decrease comorbidities • Decrease health-care costs to society • Swedish Obese Subjects study, which started in 1987
  • 9. SELECTION CRITERIA • International Federation for Surgery of Obesity and the National Institute for Clinical Excellence. • Body mass index (BMI) >40 kg/m2 or BMI 35–39 kg/m2 with comorbid disease • Minimum of 5 years obesity • Failure of conservative treatment • No alcoholism or major untreated psychiatric illness • Avoid if likely to get pregnant within 2 years • Age limits 18–55 (relative) • Acceptable operative risk on preoperative assessment
  • 11. PLANNING • No bariatric operation will produce optimal long-term results without significant changes in diet, exercise,and lifestyle. • Low carbohydrate diet for atleast 2 weeks . • “I will never go back to being the way I was before.”
  • 12. PER-OPERATIVE ASSESSMENT • Before the clinical visit • medically supervised diet • Initial Clinic Visit • Group presentation on preoperative and postoperative nutritional issues by the nutritionist • Individual assessment by the surgeon’s team • Individual counseling session with the surgeon • Individual counseling session with the nutritionist • Screening blood tests
  • 13. • Subsequent Events and Evaluations • Screening flexible upper endoscopy • Screening ultrasound of the gallbladder • Subsequent Clinic Visits • Counseling session with the surgeon (including selection of the date for surgery) • Education session with the nurse educator • Preoperative evaluation by the anesthesiologist • Final paperwork by the preadmissions center
  • 14. SPECIAL EQUIPMENT • Hydraulically operated table accommodating up to 800 lb. • Side attachments • Foam cushioning • Extra large SCD stockings • Wide and secure padded straps for the abdomen and legs
  • 15. • High-flow insufflators • Extra-long staplers • Atraumatic graspers • Extra-long trocars • An ultrasonic scalpel • A fixed retractor device for clamping and holding the liver retractor is also essential.
  • 17. MEDICAL TREATMENT • Diets • Exercise • Slimming clubs • Pharmacological agents. • 97 per cent long-term failure rate
  • 18. SURGICAL OPTIONS • Restrictive • Vertical banded gastroplasty (VBG) • Laparoscopic adjustable gastric banding (AGB) • Laparoscopic sleeve gastrectomy (LSG) • Largely Restrictive, Mildly Malabsorptive • Roux-en-Y gastric bypass (RYGB) • Largely Malabsorptive, Mildly Restrictive • Biliopancreatic diversion (BPD) • Duodenal switch (DS)
  • 19. VERTICAL BAND GASTROPLASTY • Abandoned • Poor long-term weight loss • High rate of late stenosis of the gastric outlet • Regain of weight
  • 20. LAPROSCOPIC ADJUSTIBLE GASTRIC BANDING • FDA approved LAP-BAND and REALIZE BAND • Principle : Augment the early satiety, Vagal nerves feedback mechanism • Advantage : Adjustability and Low morbidity and mortality . • Ideal method for patients with BMI 35 - 40kg/m² • 0.1% perioperative mortality rate
  • 21. • 15mm pneumoperitoneum left upper quadrant, at the midclavicular line, one hand breath below the xiphoid. • 12-mm camera port in the midline approximately 15 cm from the xiphoid. • 5-mm port is placed in the right upper quadrant for the surgeon’s left hand. • 5-mm port in the left upper quadrant is placed for the assistant • Port in the epigastrium is placed to assist in retracting the left lobe of the liver
  • 22.
  • 23.
  • 24. SLEEVE GASTRECTOMY • 0.2 per cent operative mortality. • Removes most of the grehlin • Disadvantage : leakage, sleeve expansion • 65 per cent weight loss by 2 years • 10-20% resleeve procedure
  • 25.
  • 26.
  • 27. ROUX-EN-Y GASTRIC BYPASS • 65–75 per cent excess weight loss • Risk 0.5 per cent • Uses : GERD or type 2 diabetes. • Limitation : Decreases Iron absorption . • Theories : Foregut and Hind gut theory proposed for weight loss
  • 28.
  • 29. BILIOPANCREATIC DIVERSION – WITH OR WITHOUT A DUODENAL SWITCH • 75–85 per cent excess • Mortality of 1–2 per cent • Extreme malabsorption
  • 31. RESULTS • How to define success? • Losing at least 50 per cent of the excess weight in the first 12–24 months. • Decrease comorbidities • Improved quality of life .
  • 33.
  • 34. EMERGING TRENDS • Neuromodulation using • Gastric-implanted electrodes • Vagal blocking using electrodes around the abdominal vagus, • Endoscopically placed intraluminal sleeves • Endoscopic gastric restriction • Single incision and transvaginal approaches.
  • 35. BEFORE AND AFTER VERTICAL SLEEVE GASTRECTOMY
  • 36.
  • 37.
  • 38.

Editor's Notes

  1. (35cm proximal jejunal anastomosis to 10cm of terminal ileum ) ) (250cm distal roux limb , 50 cm terminal ileum )
  2. Genetic causes fat and obesity gene FTO GENE , and mc4r gene