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PITUITARY GLAND
Guided By:
Shashanka K
Prasad
Dept. Of Molecular
Biology
1
Presented By:
Inchara R
4th Semester
Molecular
Biology
16/03/2019
INTRODUCTION
2
CONTENTS
 Introduction
 Location & Structure
 Development of pituitary gland
 Hormones of pituitary gland
 Functions of pituitary gland
 Disorders of pituitary gland
 Conclusion
 References
 Acknowledgement
3
LOCATION & STRUCTURE
4
Fig 1: Location of the pituitary gland in skull.
5
Fig 3: Parts of pituitary gland.Fig 2: Location of the pituitary gland in brain.
6Development Of Pituitary Gland
Fig 4: Events Occurring between 5 to 16 weeks of age
Posterior Pituitary Hormone
7
1. Antidiuretic hormone:
 Role- ADH is a water-conservation hormone.
 Actions- Retention of water & Vasopressor action.
Fig 5: Kidney
8
2. Oxytocin
 Role- Oxytocin is an important reproductive hormone.
 Actions- In females, oxytocin acts on mammary glands and uterus.
Fig 6: Uterus Fig 7: Mammary Gland
Anterior Pituitary Hormone
9
Fig 8: Bones
1. Growth Hormone:
 Role- General growth of body.
 Action- On metabolism
- On bone.
10
2. Prolactin:
Role- Milk production by the mammary glands of lactating females.
Action- Enhance progesterone secretion by the ovaries after ovulation.
- No role for this hormone has been clearly established in males.
Fig 9: Mammary Gland
Prolacti
n
11
3. Thyroid-Stimulating Hormone:
Role- Growth and activity of the thyroid gland.
Action- It influences the uptake of iodine, the synthesis of the hormones,
thyroxin and tri-iodothyronine by the thyroid gland and the release of stored
hormones into the blood stream.
Fig 10: Thyroid Gland
12
4. Adrenocorticotropic Hormone:
 Role- Stimulates the cortex of the adrenal gland to produce its hormones.
 Action- Regulates chronic stress.
Fig 11: Adrenal Cortex
13
Fig 12: Skin
5. Melanocyte-stimulating hormone:
Role- Skin pigmentation.
Action- MSH binds to membrane-bound receptors on skin melanocytes and
stimulates increased melanin.
14
Fig 13: Ovaries Fig 14: Testis
6. Follicle-Stimulating Hormone & Luteinizing Hormone:
 Role- Regulating reproductive Organs.
 Action- Stimulate the production of gametes.
- Production of reproductive hormones.
PITUITARYDISORDERS
 Dwarfism:
• Cause - By the deficiency of growth hormones.
• Effects- Small proportioned body and sexual immaturity.
 Diabetes Insipidus:
• Cause- By the deficiency of ADH.
• Effects- Excess excretion of water through urine.
15
Hypoactivity Of Pituitary Gland
 Simmonds's Disease:
 Cause- By the hyposecretion of anterior pituitary hormones
- Atrophy or degeneration of anterior lobe pituitary gland.
 Effects- Skin of face becomes dry and wrinkled, premature ageing.
16
Hyperactivity of Pituitary Gland
 High Blood Level of ADH:
 Cause- By excessive secretion of ADH.
 Effects- Excessively dilute blood and low plasma sodium.
17
 Acromegaly:
 Cause- By the excess of growth hormone after adult size is reached.
 Effects- Disproportionate increase in size of bones of face, hands & feet.
 Gigantism:
 Cause- By excess of growth hormone from early age.
 Effects- Large and well proportioned body.
18
CONCLUSION
19
REFERENCES
 Cinnamon L. VanPutte, Jennifer L. Regan, Andrew F. Russo. 2008 Seeley’s
anatomy & physiology, eleventh edition, McGraw-Hill Education, New York, USA,
1262pp.
 Arthur C. Guyton, John E. Hall. 2006 Textbook of Medical Physiology, eleventh
edition, Elsevier’s Health Sciences Rights Department, Philadelphia, USA, 1152pp.
 K Sembulingam and Prema Sembulingam. 2012. Essentials of Medical Physiology,
Sixth Edition, Jaypee brothers medical publishers Ltd, New Delhi, 1113pp.
 www.jiniordentist.com/hormones-released-from-pituitary-gland-and-their-
functions.html
 www.biologydiscussion.com/human-physiology/pituitaryglands/44964
20
ACKNOWLEGDEMENT
I would like to thank the dept. of Molecular Biology for providing this
opportunity to present this seminar.
I would also like to thank my guide Shashanka sir for his valuable
guidance.
Thank you one and all.
21

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Pituitary Gland

  • 1. PITUITARY GLAND Guided By: Shashanka K Prasad Dept. Of Molecular Biology 1 Presented By: Inchara R 4th Semester Molecular Biology 16/03/2019
  • 3. CONTENTS  Introduction  Location & Structure  Development of pituitary gland  Hormones of pituitary gland  Functions of pituitary gland  Disorders of pituitary gland  Conclusion  References  Acknowledgement 3
  • 4. LOCATION & STRUCTURE 4 Fig 1: Location of the pituitary gland in skull.
  • 5. 5 Fig 3: Parts of pituitary gland.Fig 2: Location of the pituitary gland in brain.
  • 6. 6Development Of Pituitary Gland Fig 4: Events Occurring between 5 to 16 weeks of age
  • 7. Posterior Pituitary Hormone 7 1. Antidiuretic hormone:  Role- ADH is a water-conservation hormone.  Actions- Retention of water & Vasopressor action. Fig 5: Kidney
  • 8. 8 2. Oxytocin  Role- Oxytocin is an important reproductive hormone.  Actions- In females, oxytocin acts on mammary glands and uterus. Fig 6: Uterus Fig 7: Mammary Gland
  • 9. Anterior Pituitary Hormone 9 Fig 8: Bones 1. Growth Hormone:  Role- General growth of body.  Action- On metabolism - On bone.
  • 10. 10 2. Prolactin: Role- Milk production by the mammary glands of lactating females. Action- Enhance progesterone secretion by the ovaries after ovulation. - No role for this hormone has been clearly established in males. Fig 9: Mammary Gland Prolacti n
  • 11. 11 3. Thyroid-Stimulating Hormone: Role- Growth and activity of the thyroid gland. Action- It influences the uptake of iodine, the synthesis of the hormones, thyroxin and tri-iodothyronine by the thyroid gland and the release of stored hormones into the blood stream. Fig 10: Thyroid Gland
  • 12. 12 4. Adrenocorticotropic Hormone:  Role- Stimulates the cortex of the adrenal gland to produce its hormones.  Action- Regulates chronic stress. Fig 11: Adrenal Cortex
  • 13. 13 Fig 12: Skin 5. Melanocyte-stimulating hormone: Role- Skin pigmentation. Action- MSH binds to membrane-bound receptors on skin melanocytes and stimulates increased melanin.
  • 14. 14 Fig 13: Ovaries Fig 14: Testis 6. Follicle-Stimulating Hormone & Luteinizing Hormone:  Role- Regulating reproductive Organs.  Action- Stimulate the production of gametes. - Production of reproductive hormones.
  • 15. PITUITARYDISORDERS  Dwarfism: • Cause - By the deficiency of growth hormones. • Effects- Small proportioned body and sexual immaturity.  Diabetes Insipidus: • Cause- By the deficiency of ADH. • Effects- Excess excretion of water through urine. 15 Hypoactivity Of Pituitary Gland
  • 16.  Simmonds's Disease:  Cause- By the hyposecretion of anterior pituitary hormones - Atrophy or degeneration of anterior lobe pituitary gland.  Effects- Skin of face becomes dry and wrinkled, premature ageing. 16
  • 17. Hyperactivity of Pituitary Gland  High Blood Level of ADH:  Cause- By excessive secretion of ADH.  Effects- Excessively dilute blood and low plasma sodium. 17
  • 18.  Acromegaly:  Cause- By the excess of growth hormone after adult size is reached.  Effects- Disproportionate increase in size of bones of face, hands & feet.  Gigantism:  Cause- By excess of growth hormone from early age.  Effects- Large and well proportioned body. 18
  • 20. REFERENCES  Cinnamon L. VanPutte, Jennifer L. Regan, Andrew F. Russo. 2008 Seeley’s anatomy & physiology, eleventh edition, McGraw-Hill Education, New York, USA, 1262pp.  Arthur C. Guyton, John E. Hall. 2006 Textbook of Medical Physiology, eleventh edition, Elsevier’s Health Sciences Rights Department, Philadelphia, USA, 1152pp.  K Sembulingam and Prema Sembulingam. 2012. Essentials of Medical Physiology, Sixth Edition, Jaypee brothers medical publishers Ltd, New Delhi, 1113pp.  www.jiniordentist.com/hormones-released-from-pituitary-gland-and-their- functions.html  www.biologydiscussion.com/human-physiology/pituitaryglands/44964 20
  • 21. ACKNOWLEGDEMENT I would like to thank the dept. of Molecular Biology for providing this opportunity to present this seminar. I would also like to thank my guide Shashanka sir for his valuable guidance. Thank you one and all. 21