This gives knowledge about the respiratory problems and their solutions.

1. NASAL PREPARATIONS

2. NASAL PREAPREATIONS ARE
THE PRODUCTS APPLIED IN
THE NOSE TO TREAT THE
CONDITIONS OF NOSE OR
NASAL SYMPTOMS.
DEFINITION:

3. THEY INCLUDES MEDICINES
SUCH AS NASAL STEROIDS,
LUBRICANTS,ANTI-HISTAMIES,
DECONGESTANTS AND ANTI-
INFECTIVES.
EXAMPLES:

4. THEY ARETHE SOLUTIONS,SPRAYSOR JELLIES
ISOTONICTO NASAL FLUIDSBUFFERED TO
MAINTAIN DRUG STABILITYWHILE
APPROXIMATINGTHE NORMALPH RANGETO THE
NASAL FLUID(5.5-6.5) ANDSTABILIZEDAND
PRESERVED ASREQUIRED
PROPERTIES:

5. THEY ARE AVAILABLEAS:
• NOSE DROPS
• NOSE SPRAYS
• NASAL JELLIES
• INHALERS
DOSAGE FORMS:

6. • EASY OF USE AND
CONVENIENCE
• SAVE TIME
• RAPIDLY EFFECTIVE
• PAINLESS
• NO NEEDLE STICK RISK
• HIGH PATIENT COMPLIANCE
• FASTER CARE AND DISCHARGE
• SAFE TO USE
ADVANTAGES:

7. • LOW BIOAVAILABILITY
• DRUG ELIMINATION
• IRREVERSIBLE DAMAGE TO NASAL
MUCOSA
• DRUG DOSE LOSS DUE TO
IMPROPER USE
• LIMITED DOSE
DISADVANTAGES:

8. THAY ARE USED FOR THE TREATMENT OF
THE FOLLOWING:
• RHINITIS OF COMMON COLD
• VASOMOTOR AND ALLERGIC RHINITIS
INCLUDING HAY FEVER
• SINUSITIS
• CONGESTION
• INFECTIONS
USES:

9. MOST NASAL DECONGESTANT ARE
AQUEOUS PREPARATIONS
THE CONCENTRATION OF ADRENERGIC
AGENTS IN MAJORITY OF NASAL
DECONGESTANTS IS QUITE LOW ABOUT
0.05%-1.0%
NASAL DECONGESTANT
SOLUTIONS:
A DECONGESTANT OR NASAL
DECONGESTANT IS A TYPE OF
PHARMACEUTICAL DRUG THA IS USED
TO RELIVE NASAL CONGESTION IN THE
UPPER RESPIRATORY TRACT.

10. THE ACTIVE INGREDIENT IN
THE NASAL DECONGESTANT
SOLUTIONS ARE EITHER:
• PHENYLEPHRINE
• PSUEODOEPHRINE
• OXYMETAZOLINE
THEY ARE AVAILABLEIN BOTH
ADULTS AND PEDIATRIC(1/2
OF ADULTS STRENGTH) USE

11. • THEY ARE VOLATILE AT ROOM TEMPERATURE.
• THE MEDICATION WHICH HAVE AMINE LIKE
ODOUR IS MASKED WITH ADDED AROMATICS.
• THE INHALERS IN WHICH DRUG IS HELD CONTAIN
CYLINDRICAL ROLLS OF FIBROUS MATERIAL
IMPREGNATED WITH VOLATILE DRUGS,THEY ARE
EFFECTIVE SO LONG.
THE ACTIVE INGREDIENT IN THE INHALERS ARE:
• SALBUTAMOL
DECONGESTANT INHALERS:

12. NASAL SOLUTIONS ARE
USUALLY PACKED IN
DROPPER BOTTLES OR IN
PLASTIC BOTTLE SPRAYS
CONTAINING 15-30ML OF
MEDICATION
PACKAGING:

13. THANK YOU