Nano

1. Nanomaterials
Esha Ghazanfar (MM2333)

2. OUTLINE
• Title
• Objectives
• Novelty
• Methodology
• Preparation of Ti Substrate
• Anodization
• Annealing
• Synthesis of Zein NPs
• Synthesis of MBGNs
• Preparation of herb
• EPD coatings
• Material characterization
techniques
09-05-2023 Nanomaterials 2

3. TITLE
Electrophoretic Deposition(EPD) of
Commiphora wightii (mukul), Zein/Mesoporous
Bioactive Glass Nanoparticles (MBGNs) on
pure Titanium for Orthopedic Applications
.
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4. Objectives
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Zein NPs-MBGNs-Commiphora wightii composite coating
1
To deposit uniform
coatings on substrate
2
To design coatings for
implants with enhanced
bioactivity
3
To prevent bacterial film
formation

5. SUBSTRATE PREPARATION
Pure Titanium

6. Annealing of Anodized Samples
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Process Parameters
Temperature 500˚C
Heating Rate
5˚C per
minute
Time 4 hours

7. Synthesis of
Mesoporous
Bioactive Glass
Nanoparticles
(MBGNs)
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8. SEM/EDX of Zein NPs
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Diameter of Zein NPs Elemental analysis of Zein NPs

9. SEM of Zein NPs / MBGNs/ Herb Coating
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10. SEM After Bioactivity Test
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11. Conclusions
• Homogenous and uniform distribution of Zein NPs and MBGNs over
substrate
• Bioactivity was confirmed via HA layer formation
• Inhibited biofilm formation on coated substrate due to; Commiphorine
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12. Future Perspectives
Coatings can be further examined for
• Protein adsorption
• Zeta potential results
• Drug release studies
• Cytocompatibility (with bone-cells)
• In-vivo trials
To get more better properties and to mimic further bone structure
• Change of scaffold from pure Ti to Ti-Cu alloy for better antibacterial
activity and biocompatibility
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13. Future Perspectives
Ti-Cu Alloy scaffold by powder metallurgy
Synthesis of nanoparticles of Starch/ PVA/ Chitosan
Synthesis of Hydroxyapatite Nanoparticles(HA)/ MBGNs
Selection of Herb lemongrass/ Moringa/ Cinnamon
powder
EPD of composite coating on Ti-Cu based porous Alloy
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14. References
1. [C. N. Elias, J. H. C. Lima, R. Valiev, and M. A. Meyers, “Biomedical applications of titanium and its
alloys,” JOM, vol. 60, no. 3, pp. 46–49, Mar. 2008, doi: 10.1007/s11837-008-0031-1.
2. 2. Y. Li et al., “Enhanced antibacterial properties of orthopedic implants by titanium nanotube surface
modification: a review of current techniques,” Int. J. Nanomedicine, vol. 14, pp. 7217–7236, Sep.
2019, doi: 10.2147/IJN.S216175.
3. 3. F. Maciąg, T. Moskalewicz, K. Kowalski, A. Łukaszczyk, Z. Hadzhieva, and A. R. Boccaccini, “The
Effect of Electrophoretic Deposition Parameters on the Microstructure and Adhesion of Zein Coatings
to Titanium Substrates,” Materials, vol. 14, no. 2, Art. no. 2, Jan. 2021, doi: 10.3390/ma14020312.
4. 4. N. Meyer, L. R. Rivera, T. Ellis, J. Qi, M. P. Ryan, and A. R. Boccaccini, “Bioactive and
Antibacterial Coatings Based on Zein/Bioactive Glass Composites by Electrophoretic Deposition,”
Coatings, vol. 8, no. 1, Art. no. 1, Jan. 2018, doi: 10.3390/coatings8010027.
5. 5. [5] Rao, J. P., and Geckeler, K. E. (2011). Polymer nanoparticles: preparation techniques and size-
control parameters. Prog. Polym. Sci. 36, 887–913. doi: 10.1016/j.progpolymsci.2011.01.001
6. 6. Chen, H., & Zhong, Q., A novel method of preparing stable zein nanoparticle dispersions for
encapsulation of peppermint oil, Food Hydrocolloids (2014),
http://dx.doi.org/10.1016/j.foodhyd.2014.07.018
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15. THANK YOU
Dr. Mohsin Ali
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