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OPTIC NERVE
ANATOMY
OPTIC NERVE
CNII: OVERVIEW
▸ The optic nerve (CN II) is the second cranial nerve, responsible
for transmitting the special sensory information for vision
▸ It is developed from the optic vesicle, an outpocketing of the forebrain
▸ The optic nerve can therefore be considered part of the central nervous
system, and examination of the nerve enables an assessment of
intracranial health
▸ Due to its unique anatomical relation to the brain, the optic nerve is
surrounded by the cranial meninges (not by epi-, peri- and
endoneurium like most other nerves)
https://teachmeanatomy.info/head/cranial-nerves/optic-cnii/
OPTIC NERVE
CNII: ANATOMICAL COURSE
▸ The anatomical course of the optic nerve 
describes the transmission of special sensory
information
▸ from the retina of the eye
▸ to the primary visual cortex of the brain
▸ It can be divided into extracranial (outside the
cranial cavity) and intracranial components
OPTIC NERVE
CNII: ANATOMICAL COURSE - EXTRACRANIAL
▸ The optic nerve is formed by the convergence of axons
from the retinal ganglion cells
▸ These cells in turn receive impulses from the photoreceptors of
the eye (the rods and cones)
▸ After its formation, the nerve leaves the bony orbit via the optic
canal, a passageway through the sphenoid bone
▸ It enters the cranial cavity, running along the surface of
the middle cranial fossa (in close proximity to the pituitary
gland)
OPTIC NERVE
CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY)
▸ Within the middle cranial fossa, the optic nerves from each eye
unite to form the optic chiasm
▸ At the chiasm, fibres from the nasal (medial) half of each retina
cross over to the contralateral optic tract, while fibres from the
temporal (lateral) halves remain ipsilateral:
▸ Left optic tract – contains fibres from the left temporal
(lateral) retina, and the right nasal (medial) retina.
▸ Right optic tract – contains fibres from the right temporal
retina, and the left nasal retina
https://teachmeanatomy.info/head/cranial-nerves/optic-cnii/
OPTIC NERVE
CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY)
▸ Each optic tract travels to its corresponding
cerebral hemisphere to reach the lateral
geniculate nucleus (LGN)
▸ LGN is a relay system located in the thalamus
where the fibres synapse
▸ Axons from the LGN then carry visual information
via pathways known as the optic radiations
OPTIC NERVE
CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY)
▸ The pathway itself can be divided into:
▸ Upper optic radiation
▸ carries fibres from the superior retinal quadrants (corresponding to the
inferior visual field quadrants)
▸ travels through the parietal lobe to reach the visual cortex
▸ Lower optic radiation
▸ carries fibres from the inferior retinal quadrants (corresponding to the
superior visual field quadrants)
▸ travels through the temporal lobe, via a pathway known as Meyers’
loop, to reach the visual cortex
OPTIC NERVE
CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY)
▸ Once at the visual cortex, the brain
processes the sensory data and
responds appropriately
https://teachmeanatomy.info/head/cranial-nerves/optic-cnii/
https://teachmeanatomy.info/head/cranial-nerves/optic-cnii/
https://teachmeanatomy.info/head/cranial-nerves/optic-cnii/
References
▸ These slide reflect a summary of the contents of
TeachMeAnatomy.info and are to be used for
educational purposes only in compliance with the
terms of use policy.
Specific portions referenced in this summary are as
follows:
▸ https://teachmeanatomy.info/head/cranial-nerves/
optic-cnii/
Additional sources are referenced on the slide
containing that specific content.

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Optic nerve

  • 2. OPTIC NERVE CNII: OVERVIEW ▸ The optic nerve (CN II) is the second cranial nerve, responsible for transmitting the special sensory information for vision ▸ It is developed from the optic vesicle, an outpocketing of the forebrain ▸ The optic nerve can therefore be considered part of the central nervous system, and examination of the nerve enables an assessment of intracranial health ▸ Due to its unique anatomical relation to the brain, the optic nerve is surrounded by the cranial meninges (not by epi-, peri- and endoneurium like most other nerves)
  • 4. OPTIC NERVE CNII: ANATOMICAL COURSE ▸ The anatomical course of the optic nerve  describes the transmission of special sensory information ▸ from the retina of the eye ▸ to the primary visual cortex of the brain ▸ It can be divided into extracranial (outside the cranial cavity) and intracranial components
  • 5. OPTIC NERVE CNII: ANATOMICAL COURSE - EXTRACRANIAL ▸ The optic nerve is formed by the convergence of axons from the retinal ganglion cells ▸ These cells in turn receive impulses from the photoreceptors of the eye (the rods and cones) ▸ After its formation, the nerve leaves the bony orbit via the optic canal, a passageway through the sphenoid bone ▸ It enters the cranial cavity, running along the surface of the middle cranial fossa (in close proximity to the pituitary gland)
  • 6. OPTIC NERVE CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY) ▸ Within the middle cranial fossa, the optic nerves from each eye unite to form the optic chiasm ▸ At the chiasm, fibres from the nasal (medial) half of each retina cross over to the contralateral optic tract, while fibres from the temporal (lateral) halves remain ipsilateral: ▸ Left optic tract – contains fibres from the left temporal (lateral) retina, and the right nasal (medial) retina. ▸ Right optic tract – contains fibres from the right temporal retina, and the left nasal retina
  • 8. OPTIC NERVE CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY) ▸ Each optic tract travels to its corresponding cerebral hemisphere to reach the lateral geniculate nucleus (LGN) ▸ LGN is a relay system located in the thalamus where the fibres synapse ▸ Axons from the LGN then carry visual information via pathways known as the optic radiations
  • 9. OPTIC NERVE CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY) ▸ The pathway itself can be divided into: ▸ Upper optic radiation ▸ carries fibres from the superior retinal quadrants (corresponding to the inferior visual field quadrants) ▸ travels through the parietal lobe to reach the visual cortex ▸ Lower optic radiation ▸ carries fibres from the inferior retinal quadrants (corresponding to the superior visual field quadrants) ▸ travels through the temporal lobe, via a pathway known as Meyers’ loop, to reach the visual cortex
  • 10. OPTIC NERVE CNII: ANATOMICAL COURSE - INTRACRANIAL (VISUAL PATHWAY) ▸ Once at the visual cortex, the brain processes the sensory data and responds appropriately
  • 14.
  • 15. References ▸ These slide reflect a summary of the contents of TeachMeAnatomy.info and are to be used for educational purposes only in compliance with the terms of use policy. Specific portions referenced in this summary are as follows: ▸ https://teachmeanatomy.info/head/cranial-nerves/ optic-cnii/ Additional sources are referenced on the slide containing that specific content.