The document discusses the key differences between matter, volume, mass, and weight. Matter is anything that takes up space and has mass, while volume refers to the amount of space an object occupies. Mass is a measure of the amount of matter in an object and remains constant regardless of location, whereas weight depends on gravitational force and can vary depending on location. Mass is measured using a balance and expressed in grams, while weight is measured using a spring scale and expressed in Newtons.