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Farmakologi dan Mekanisme Kerja Doksisiklin ,[object Object]

FORMULA ,[object Object],[object Object],[object Object],[object Object],No. Nama Bahan Fungsi Bahan % Lazim % mg/kapsul kg/batch 1. 2. 3. Doksisiklin HCl Aerosil Talkum Zat Aktif Adsorben, Glidan Pengisi - 0,1-0,5 5-30 80 0,5 19,5 100 0,625 24,375 10 0,0625 2,4375

Formula 2 ,[object Object],[object Object],[object Object],[object Object],No. Nama Bahan Fungsi Bahan % Lazim % mg/kapsul kg/batch 1. 2. 3. 4. Doksisiklin HCl Aerosil Talkum Laktosa Zat Aktif Adsorben, Glidan Glidan Pengisi - 0,1-0,5 1-5 - 80 0,5 5 14,5 100 0,625 6,250 18,125 10 0,0625 0,625 1,8125

Penimbangan bahan baku Pengayakan Pencampuran ,[object Object],[object Object],IPC Pengisian ,[object Object],[object Object],[object Object], Polishing ,[object Object],[object Object],[object Object],Alur kerja produksi doksisiklin kapsul

PEMBUATAN DOKSISIKLIN KAPSUL ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object]

PENGUJIAN ,[object Object],[object Object]

Bobot rata-rata isi kapsul Perbedaan bobot isi kapsul dalam % A B 120 mg atau lebih Lebih dari 120 mg ± 10 % ± 7,5 % ± 20 % ± 15 %

PEMBAHASAN ,[object Object],[object Object]

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