4. •The recent article
about MERS was
published from the
New York city in the
magazine The Scientist
in January 2018.
5. Camel flu.
Middle East Respiratory Syndrome is a Viral
Respiratory Disease.
It is caused by a Novel
Positive sense, single
Stranded RNA Virus
named Coronavirus.
7. It was 1st discovered in 1960.
The name is derived from Latin word CORONA
meaning “crown” or “halo”.
It infects upper
Respiratory and
Gastrointestinal
tract of mammals
and birds.
8. •Severe Acute Respiratory Syndrome-
SARS caused by Coronavirus.
•Identified in 2002 in China.
•Initial symptoms: FLU
LETHARGY
COUGH
SORE THROAT
FEVER.
9. •Between November 2002 and July
2003, an outbreak of SARS in Southern
China caused an eventual 8,098 cases.
•That results in 774 deaths in 37
countries.
10.
11. Non-human to human transmission.
Human to human transmission.
12.
13.
14. Detection of Viral Nucleic Acids.
Serology.
Positive Real Time Reverse
Transcription PCR.
18. As of January 20, 2017, the
WHO had received reports from
27 countries of 1879 cases of
laboratory-confirmed MERS and
at least 659 related deaths
(percentage of fatal cases, 35%).
Approximately 80% of reported
cases have been linked to exposure
in Saudi Arabia.
20. If it’s a “Middle
East” virus, why
is it exploding all
the way in
Korea?
21. It all started with ONE man.
On 25th May 2015, the Republic of Korea
notified WHO of the FIRST laboratory-
confirmed case of MERS-CoV.
22. Recent travellers from the Arabian Peninsula.
Close contacts of an ill traveller from Arabian
Peninsula.
People recently in healthcare facility.
Close contacts of a confirmed case of MERS.
Healthcare personnel.
People with exposure to camels.
High risk groups for severe MERS.
23.
24. Origin, history, modes and exact routes of
transmission, pathogenesis, viral kinetics and
underlying mechanisms of protective immunity
are still unknown.
This lack of knowledge is hindering the
development of drug treatment, adjunctive
treatments, specific diagnostic tests,
biomarkers, and vaccines.