Histone H2B is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Histone H2B is a structural protein that helps organise eukaryotic DNA. It plays an important role in the biology of the nucleus where it is involved in the packaging and maintaining of chromosomes, regulation of transcription, and replication and repair of DNA. Histone H2B helps regulate chromatin structure and function through post-translational modifications and specialised histone variants. The antibody detects endogenous Histone H2B (Di Methyl Lys43) protein. Anti-Histone H2B (Di Methyl Lys43) Antibody- http://www.stjohnslabs.com/histone-h2b-di-methyl-lys43-antibody?filter_name=STJ97164 Join our Antibody Validation Project - http://www.stjohnslabs.com/services/antibody-validation