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Copyright © McGraw-Hill Education. Permission required for reproduction or display.
Chapter 01
Lecture Outline
See separate PowerPoint slides for all figures and tables pre-
inserted into PowerPoint without notes.
• Early healers depended on
superstition and magic
• Followed by observations of
injuries, wound healing and
dead bodies
• This evolved into
experimentation and
creation of new terminology
for anatomy & physiology
• Finally, study of corpses
and cadaver dissection
brought new knowledge of
human body
1.1: Origins of Medical Science
2
1.2: Anatomy &
Physiology
• Anatomy: The study of the
structure/morphology of the
human body and its parts;
derived from Greek for “a cutting
up”
• Physiology: The study of the
functions of the human body and
its parts; derived from Greek for
“relationship to nature”
• The structure of organs and parts
of the human body determines
the function.
3
1.3: Levels of Organization
4
All materials, living or
non-living, are
composed of chemicals,
which consist of atoms.
All materials, living or
non-living, are
composed of chemicals,
which consist of atoms.
Subatomic Particles:
protons, neutrons, and
electrons that make up
cells
Subatomic Particles:
protons, neutrons, and
electrons that make up
cells
Atom: tiny particles that
make up chemicals
(hydrogen, carbon)
Atom: tiny particles that
make up chemicals
(hydrogen, carbon)
Molecule: particles
consisting of atoms
(water, glucose)
Molecule: particles
consisting of atoms
(water, glucose)
Macromolecule: large
particles consisting of
molecules (DNA,
protein)
Macromolecule: large
particles consisting of
molecules (DNA,
protein)
Organelle: functional
part of a cell
(mitochondrion,
lysosome)
Organelle: functional
part of a cell
(mitochondrion,
lysosome)
Cell: basic unit of
structure and functions
(muscle, nerve, or blood
cell)
Cell: basic unit of
structure and functions
(muscle, nerve, or blood
cell)
Tissue: layer or mass of
cells with specific
function (adipose
tissue)
Tissue: layer or mass of
cells with specific
function (adipose
tissue)
Organ: group of
different tissues with a
function (heart, kidney,
stomach)
Organ: group of
different tissues with a
function (heart, kidney,
stomach)
Organ System: group of
organs with common
function (digestive
system)
Organ System: group of
organs with common
function (digestive
system)
Organism: composed of
organ systems
interacting (human)
Organism: composed of
organ systems
interacting (human)
Levels of Organization
5
1.4:
Characteristics
of Life
•The events inside the body which obtain, release,
and utilize energy are the main part of metabolism
(all of the chemical reactions in an organism that
support life).
6
TABLE 1.3 Requirements of Organisms
Factor Characteristic Use Factor Characteristic Use
Water
Food
Oxygen
A chemical substance
Various chemical
substances
A chemical substance
For metabolic processes, as a
medium for metabolic reactions,
to carry substances, and to
regulate body temperature
To supply energy and raw
materials for the production of
necessary substances and for
the regulation of vital reactions
To help release energy from
food substances
Heat
Pressure
A form of energy
A force
To help regulate the rates of
metabolic reactions
Atmospheric pressure for
breathing; hydrostatic
pressure
to help circulate blood
Table 1.3
Copyright © McGraw-Hill Education. Permission required for reproduction or display.
1.6: Organization of the Human Body
Cranial Cavity
Vertebral Canal
1.6: Organization of the Human Body
Thoracic Cavity
Diaphragm
Abdominopelvic Cavity
Abdominal Cavity Pelvic Cavity
Mediastinum Pulmonary Cavity
Major Body Cavities
• Diaphragm: Muscle that separates the thoracic and
abdominopelvic cavities
• Mediastinum: Region between lungs in thoracic cavity, which
contains heart, esophagus, trachea, thymus gland
• Abdominopelvic cavity contains 2 portions:
a. Abdominal cavity: Extends from diaphragm to top of
pelvis, and contains stomach, liver, spleen, kidneys small
intestine, most of large intestine
b. Pelvic cavity: Enclosed by pelvic bones, and contains end
of large intestine, urinary bladder, internal reproductive
organs
16
Major Body Cavities
17
Thoracic and Abdominopelvic
Membranes
The thoracic and abdominopelvic cavities are lined by double-layered serous
membranes, which secrete serous fluid (slippery fluid that prevents friction
between layers).
Serous membranes consist of 2 layers:
• Visceral layer: inner layer, which covers an organ
• Parietal layer: outer layer, which lines wall of cavity
Examples of serous membranes:
• Visceral and parietal pleura (around lungs in thorax)
• Visceral and parietal pericardium (around heart in thorax)
• Visceral and parietal peritoneum (around abdominopelvic organs)
18
Serous membranes of the
thoracic cavity
Serous membranes of the
abdominal cavity
19
Serous
Membranes
Pleural Membranes
Visceral pleura Parietal pleura
Pleural cavity
Pericardium
Visceral pericardium
Pericardial cavity
Parietal pericardium
Peritoneum
Visceral
peritoneum
Parietal
peritoneum
Peritoneal
cavity
Lesser
omentum
Mesentery
of small intestine
Greater
omentum
Peritoneum
Organ Systems
• Integumentary system:
• Protection, body temperature
regulation, sensory reception,
production of Vitamin D
• Skeletal system:
• Framework,
protection, attachment sites,
storage of inorganic salts,
production of blood cells,
support and movement
• Muscular system:
• Movement, main source of
body heat, maintenance of
posture.
23
Organ Systems
• Nervous and
Endocrine Systems
• Integration and
coordination of
organ function
through nerve
impulses or
hormones
24
Organ Systems
• Cardiovascular system:
• Transportation of gases,
nutrients, blood cells and
wastes
• Lymphatic system:
• Transportation of fluids,
lymphocyte production,
body defense
25
Organ
Systems
• Digestive system:
• Receives food,
breaks down food,
excretes waste
• Respiratory system:
• Exchange of gases
• Urinary system:
• Removes blood
wastes, regulates
elecrolyte and
water balance,
blood pressure
26
Organ Systems
• Reproductive System:
• Male and female systems
produce and transport sex cells.
• Female also provides fetal
development and childbirth.
27
Organ Systems
28
1.7: Lifespan Changes
• Aging occurs from the microscopic to the whole-body level. These are some of the changes that
occur with aging:
• Hair loses pigment, becomes gray or white
• Skin wrinkles due to decrease in subcutaneous fat
• Skin stiffens due to decrease in collagen and elastin
• Percentage of fats in the tissues increases
• Elevated blood pressure may become hypertension
• Elevated blood glucose may become type 2 diabetes mellitus
• Tissues atrophy and organs shrink
• Cells reach end of ability to undergo cell division, as they lose tips of chromosomes
• Metabolic rate decreases
• Decreased production of enzymes and other proteins
• Some will develop dementia / Alzheimer disease
29
1.8: Anatomical
Terminology
• Anatomical Position:
• Standing erect
• Facing forward
• Upper limbs at the sides
• Palms facing forward
• Anatomical terms of relative position
are based on a person standing in
anatomical position
30
Terms of
Relative
Position
• Superior (above) / Inferior (below)
• Anterior or ventral (toward the front) / Posterior or dorsal
• (toward the back)
• Medial (toward the midline) / Lateral (away from midline)
• Bilateral (paired structures; on both sides)
• Ipsilateral (same side) / Contralateral (opposite sides)
• Proximal (close to point of attachment to trunk) / Distal (farther from point of
attachment to trunk)
• Superficial (close to body surface) / Deep (more internal)
31
32
Terms of Relative Position
Superior Inferior
Anterior Posterior
(Ventral) (Dorsal)
Medial Lateral
Proximal Distal
Deep Superficial
Body Sections or Planes
• Sagittal section: longitudinal cut that divides body into
• left and right portions
• Mid-sagittal/Median section: divides body into equal left and right portions
• Parasagittal section: sagittal section lateral to midline; divides body into unequal
left and right portions
• Transverse or Horizontal section: divides body into
• superior and inferior portions
• Coronal or Frontal section: longitudinal cut that divides
• body into anterior and posterior portions
38
Body Sections
39
Body Sections
Sagittal Plane
Midsagittal Plane
Transverse Plane
Coronal Plane
Oblique Plane
Body Sections: The Brain
46
Sagittal Section Transverse Section Frontal section
Body Sections in Cylindrical Organs
47
Cross section Oblique section Longitudinal section
These sections are found in organs such as blood vessels, the
ureter, the trachea, or the intestines.
Body Regions and Quadrants
48
Abdominal Regions Abdominal Quadrants
Rt. Hypochondriac
Epigastric
Lt. Hypochondriac
Rt. Lumbar Lt.Lumbar
Umbilical
Rt. Iliac Lt. Iliac
Pelvic
Body
Regions
Nine Abdominal Regions
Rt. Hypochondriac Lt. Hypochondriac
Rt. Lumbar
Lt. Lumbar
Rt. Iliac Lt. Iliac
Epigastric
Umbilical
Pelvic
Abdominal Quadrants
Upper Right Lower Right Upper Left Lower Left
Abdominal Quadrants
Upper Right
Lower Right
Upper Left
Lower Left
Body Regions
53
Anterior regions Posterior regions
Abdominopelvic Region
Back
Back Scapular
region
Triangle of
auscultation
Vertebral
region
Sacral
region
Lumbar
region
Frontal
Mental
Nasal
Oral
Orbital
Occipital
Parietal
Temporal
Zygomatic
Buccal
Otic Facial
Cephalic
Head
Regions
Lower Limb Region
Femoral
Patellar
Crural
Tarsal Pedal
Dorsum
of foot Digits
Calcaneal
Popliteal
Gluteal
Coxal
Popliteal
Sural
Neck (Cervical) Region Anterior
cervical
Lateral
cervical
Posterior
cervical
Sternocleidomastoid

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Lecture 1-Introduction to Physiology.pdf

  • 1. 1 Copyright © McGraw-Hill Education. Permission required for reproduction or display. Chapter 01 Lecture Outline See separate PowerPoint slides for all figures and tables pre- inserted into PowerPoint without notes.
  • 2. • Early healers depended on superstition and magic • Followed by observations of injuries, wound healing and dead bodies • This evolved into experimentation and creation of new terminology for anatomy & physiology • Finally, study of corpses and cadaver dissection brought new knowledge of human body 1.1: Origins of Medical Science 2
  • 3. 1.2: Anatomy & Physiology • Anatomy: The study of the structure/morphology of the human body and its parts; derived from Greek for “a cutting up” • Physiology: The study of the functions of the human body and its parts; derived from Greek for “relationship to nature” • The structure of organs and parts of the human body determines the function. 3
  • 4. 1.3: Levels of Organization 4 All materials, living or non-living, are composed of chemicals, which consist of atoms. All materials, living or non-living, are composed of chemicals, which consist of atoms. Subatomic Particles: protons, neutrons, and electrons that make up cells Subatomic Particles: protons, neutrons, and electrons that make up cells Atom: tiny particles that make up chemicals (hydrogen, carbon) Atom: tiny particles that make up chemicals (hydrogen, carbon) Molecule: particles consisting of atoms (water, glucose) Molecule: particles consisting of atoms (water, glucose) Macromolecule: large particles consisting of molecules (DNA, protein) Macromolecule: large particles consisting of molecules (DNA, protein) Organelle: functional part of a cell (mitochondrion, lysosome) Organelle: functional part of a cell (mitochondrion, lysosome) Cell: basic unit of structure and functions (muscle, nerve, or blood cell) Cell: basic unit of structure and functions (muscle, nerve, or blood cell) Tissue: layer or mass of cells with specific function (adipose tissue) Tissue: layer or mass of cells with specific function (adipose tissue) Organ: group of different tissues with a function (heart, kidney, stomach) Organ: group of different tissues with a function (heart, kidney, stomach) Organ System: group of organs with common function (digestive system) Organ System: group of organs with common function (digestive system) Organism: composed of organ systems interacting (human) Organism: composed of organ systems interacting (human)
  • 6. 1.4: Characteristics of Life •The events inside the body which obtain, release, and utilize energy are the main part of metabolism (all of the chemical reactions in an organism that support life). 6
  • 7. TABLE 1.3 Requirements of Organisms Factor Characteristic Use Factor Characteristic Use Water Food Oxygen A chemical substance Various chemical substances A chemical substance For metabolic processes, as a medium for metabolic reactions, to carry substances, and to regulate body temperature To supply energy and raw materials for the production of necessary substances and for the regulation of vital reactions To help release energy from food substances Heat Pressure A form of energy A force To help regulate the rates of metabolic reactions Atmospheric pressure for breathing; hydrostatic pressure to help circulate blood Table 1.3 Copyright © McGraw-Hill Education. Permission required for reproduction or display.
  • 8. 1.6: Organization of the Human Body Cranial Cavity Vertebral Canal
  • 9. 1.6: Organization of the Human Body Thoracic Cavity Diaphragm Abdominopelvic Cavity Abdominal Cavity Pelvic Cavity Mediastinum Pulmonary Cavity
  • 10. Major Body Cavities • Diaphragm: Muscle that separates the thoracic and abdominopelvic cavities • Mediastinum: Region between lungs in thoracic cavity, which contains heart, esophagus, trachea, thymus gland • Abdominopelvic cavity contains 2 portions: a. Abdominal cavity: Extends from diaphragm to top of pelvis, and contains stomach, liver, spleen, kidneys small intestine, most of large intestine b. Pelvic cavity: Enclosed by pelvic bones, and contains end of large intestine, urinary bladder, internal reproductive organs 16
  • 12. Thoracic and Abdominopelvic Membranes The thoracic and abdominopelvic cavities are lined by double-layered serous membranes, which secrete serous fluid (slippery fluid that prevents friction between layers). Serous membranes consist of 2 layers: • Visceral layer: inner layer, which covers an organ • Parietal layer: outer layer, which lines wall of cavity Examples of serous membranes: • Visceral and parietal pleura (around lungs in thorax) • Visceral and parietal pericardium (around heart in thorax) • Visceral and parietal peritoneum (around abdominopelvic organs) 18
  • 13. Serous membranes of the thoracic cavity Serous membranes of the abdominal cavity 19 Serous Membranes
  • 14. Pleural Membranes Visceral pleura Parietal pleura Pleural cavity
  • 17. Organ Systems • Integumentary system: • Protection, body temperature regulation, sensory reception, production of Vitamin D • Skeletal system: • Framework, protection, attachment sites, storage of inorganic salts, production of blood cells, support and movement • Muscular system: • Movement, main source of body heat, maintenance of posture. 23
  • 18. Organ Systems • Nervous and Endocrine Systems • Integration and coordination of organ function through nerve impulses or hormones 24
  • 19. Organ Systems • Cardiovascular system: • Transportation of gases, nutrients, blood cells and wastes • Lymphatic system: • Transportation of fluids, lymphocyte production, body defense 25
  • 20. Organ Systems • Digestive system: • Receives food, breaks down food, excretes waste • Respiratory system: • Exchange of gases • Urinary system: • Removes blood wastes, regulates elecrolyte and water balance, blood pressure 26
  • 21. Organ Systems • Reproductive System: • Male and female systems produce and transport sex cells. • Female also provides fetal development and childbirth. 27
  • 23. 1.7: Lifespan Changes • Aging occurs from the microscopic to the whole-body level. These are some of the changes that occur with aging: • Hair loses pigment, becomes gray or white • Skin wrinkles due to decrease in subcutaneous fat • Skin stiffens due to decrease in collagen and elastin • Percentage of fats in the tissues increases • Elevated blood pressure may become hypertension • Elevated blood glucose may become type 2 diabetes mellitus • Tissues atrophy and organs shrink • Cells reach end of ability to undergo cell division, as they lose tips of chromosomes • Metabolic rate decreases • Decreased production of enzymes and other proteins • Some will develop dementia / Alzheimer disease 29
  • 24. 1.8: Anatomical Terminology • Anatomical Position: • Standing erect • Facing forward • Upper limbs at the sides • Palms facing forward • Anatomical terms of relative position are based on a person standing in anatomical position 30
  • 25. Terms of Relative Position • Superior (above) / Inferior (below) • Anterior or ventral (toward the front) / Posterior or dorsal • (toward the back) • Medial (toward the midline) / Lateral (away from midline) • Bilateral (paired structures; on both sides) • Ipsilateral (same side) / Contralateral (opposite sides) • Proximal (close to point of attachment to trunk) / Distal (farther from point of attachment to trunk) • Superficial (close to body surface) / Deep (more internal) 31
  • 32. Body Sections or Planes • Sagittal section: longitudinal cut that divides body into • left and right portions • Mid-sagittal/Median section: divides body into equal left and right portions • Parasagittal section: sagittal section lateral to midline; divides body into unequal left and right portions • Transverse or Horizontal section: divides body into • superior and inferior portions • Coronal or Frontal section: longitudinal cut that divides • body into anterior and posterior portions 38
  • 40. Body Sections: The Brain 46 Sagittal Section Transverse Section Frontal section
  • 41. Body Sections in Cylindrical Organs 47 Cross section Oblique section Longitudinal section These sections are found in organs such as blood vessels, the ureter, the trachea, or the intestines.
  • 42. Body Regions and Quadrants 48 Abdominal Regions Abdominal Quadrants
  • 43. Rt. Hypochondriac Epigastric Lt. Hypochondriac Rt. Lumbar Lt.Lumbar Umbilical Rt. Iliac Lt. Iliac Pelvic Body Regions
  • 44. Nine Abdominal Regions Rt. Hypochondriac Lt. Hypochondriac Rt. Lumbar Lt. Lumbar Rt. Iliac Lt. Iliac Epigastric Umbilical Pelvic
  • 45. Abdominal Quadrants Upper Right Lower Right Upper Left Lower Left
  • 46. Abdominal Quadrants Upper Right Lower Right Upper Left Lower Left
  • 47. Body Regions 53 Anterior regions Posterior regions
  • 51. Lower Limb Region Femoral Patellar Crural Tarsal Pedal Dorsum of foot Digits Calcaneal Popliteal Gluteal Coxal Popliteal Sural
  • 52. Neck (Cervical) Region Anterior cervical Lateral cervical Posterior cervical Sternocleidomastoid