4. IDEAL OF AN OXYGENATOR
• Safe and efficient
• Overcome barrier of diffusion distance
• Minimum trauma to blood cells
• Small priming volume
• Easily assmebled
• Minimize air embolism
5. • Gas transfer is proportional to partial pressure
difference and surface area and inversely
proportional to diffusion distance.
12. 1.Oxygenation chamber
• Bubble size - determined by disperser by
Orifice diameter, Gas flow rate, Blood
viscosity, Surface tension.
• sparging plate – polycarbonate plate
perforated with holes of precise dimension or
porous silicate
• Purpose : break the bulk gas into small
bubbles to allow gas exchange
13. • More the no.of bubbles- greater efficiency of
oxygenation
• Co2 diffusion is 25times > o2.Larger bubbles will
efficiently remove of co2
• Smaller bubbles will efficiently oxygenate but
poor in removal of co2
• Size : 3 — 7 mm to optimise both CO2 & O2 gas
transfer
14. 2.Debubbling/defoaming area
• Made up of Polyurethane or polyester (125-
175microm)
• Beads, sponges(polyurethane),shreds, meshes,
fabrics
• Coated with Silicon(antifoam ) reduces surface
tension of bubbles & prevents bubble formation .
Hence air embolism prevented
15. • 3. Arterial reservoir :Always positioned after
the defoaming area
16. • Advantage : easy to assemble, lower cost,
small priming vol, adequate oxy capacity
• Disadvantage : microemboli, blood cell
trauma, destruction of plasma protein due to
gas interface, defoaming capacity exhausted
with time ,excessive removal of co2
21. • Polypropylene is a heterogenous,
microporous,hydrophobic membrane
• Size- 0.03 to 0.07 Um in diameter
• Surface is hydrophobic & the pores are so
small, the blood water is not ultrafiltered;
inhibit serum leakage across the membrane
22. TRUE MEMBRANE OXYGENATOR
• COIL [Scrolled] TYPE: consists of silicone
rubber sheets coiled in a cylindrical fashion
• Silicone rubber is nonporous ; there is a
complete barrier between blood and gas.
• Eg: Sci-Med oxygenator
23. • Advantages-- Able to maintain stable CO2 &
O2 for long periods of time (weeks), Used
primarily in ECMO
• Disadvantages--Costly to manufacture, High
priming volume.