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Sleep, Vitamins and Cardiovascular Disease Dr. Stasha Gominak ETMC Neurologic Institute, 700 Olympic Plaza, 912 Tyler, TX (903) 596-3808 www.drgominak.com 1/14/2011
Why don’t we doctors know much about Sleep?  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Sleep and Headache ,[object Object],[object Object],[object Object],[object Object],[object Object]
6 years of sleep studies: 9/10 daily headache sufferers have abnormal sleep ,[object Object],[object Object],[object Object],[object Object]
Normal Sleep is a highly organized process ,[object Object]
What is Light Sleep? ,[object Object],[object Object],[object Object]
Deep Sleep: Slow Wave Sleep ,[object Object],[object Object],[object Object],[object Object]
Growth Hormone in Slow Wave Sleep may help us heal ,[object Object],[object Object],[object Object],[object Object]
Deep Sleep: REM Sleep ,[object Object],[object Object],[object Object]
9/10 daily headache sufferers in my practice have abnormal sleep ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Migraine “Brainstem Generator”  is in the same area of the brainstem where we do timing and paralysis of sleep
Posterior brainstem Periaquiductal Gray plays a large role in sleep and sleep paralysis ,[object Object],[object Object],[object Object],[object Object]
Features of my patients’ sleep disorders: (They don’t have fat necks!) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Wobbly Paralysis Switch ,[object Object],[object Object],[object Object],[object Object],[object Object],Too Paralyzed Not Paralyzed Enough
All the abnormal sleep studies have 2 common features: ,[object Object],[object Object],[object Object]
If headache improves how about other pain? ,[object Object],[object Object],[object Object],[object Object]
Why does everyone and his brother seem to have Sleep Apnea? Did we make it up? Has it always been there or is it new? What’s causing it? Why is it more in “developed countries”?
All over the world 9/10 sleep studies are abnormal. With sleep apnea comes: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
I thought Sleep Apnea only happened to fat people
Does obesity cause sleep apnea or does sleep apnea cause obesity?
Obesity and Sleep Apnea ,[object Object],[object Object],[object Object],[object Object]
Why is the CPAP experience important? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Our genetic diseases start to show up when our repair phase begins to fail ,[object Object],[object Object],[object Object],[object Object]
Using Sleep as  Therapy ,[object Object],[object Object],[object Object],[object Object]
What’s happening here that’s goofing up my patients’ sleep? Periaquiductal gray
Why don’t we fix the sleep instead of blowing air up the nose? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Vitamins and Sleep ,[object Object],[object Object],[object Object],[object Object]
Vitamin D and Sleep ,[object Object],[object Object],[object Object],[object Object]
Vitamin D receptors concentrate in 3 brain areas;  periaquiductal grey, lateral ventricles and pituitary/hypothalamus
What is Vitamin D anyway? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
In the 1970’s- 80’s Dr. Walter Stumpf “explained” what D hormone does
Dr. Walter Stumpf and D hormone ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Why would we have a hormone made by UVB that bosses the pituitary and hypothalamus? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Where are the D Receptors?  (Where they are may suggest what they do.) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Summer: High D message (70-85) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Winter: Lower D message (50-70) ,[object Object],[object Object],[object Object],[object Object]
D Hormone and Sleep ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
D Hormone not Vitamin D ,[object Object],[object Object],[object Object],[object Object]
Epidemiologically related to D deficiency- (same list as sleep apnea) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Disorders of GI tract epidemiologically related to D deficiency ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cholesterol and D Hormone ,[object Object],[object Object],[object Object],[object Object],7   dehydrocholesterol Pre vitamin D
Cholesterol and D Hormone ,[object Object],[object Object],[object Object],[object Object]
Vitamin D inflammatory connection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Autoimmune Diseases Epidemiologically linked to D deficiency ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Why did they call it a vitamin if it’s not one?   Why the “D2” and “D3” numbers ? ,[object Object],[object Object],[object Object],[object Object],[object Object]
What does this D have to do with what I do in Cardiology?
Vitamin D and Cardiovascular Dz ,[object Object],[object Object],[object Object]
Vitamin D and Cardiovascular Dz ,[object Object],[object Object],[object Object]
Vitamin D and Cardiovascular Dz ,[object Object],[object Object]
Vitamin D and Atrial Naturetic Factor ,[object Object]
Vitamin D and lipid/cholesterol ,[object Object],[object Object],[object Object]
Epidemiology is fine. What about treatment trials? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Sleep is the cure for Cardiovascular Risk Factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
How to replace the D to fix the sleep and why all the controversy about dosing? ,[object Object],[object Object],[object Object],[object Object]
What is the right level ? ,[object Object],[object Object],[object Object],[object Object]
What’s the right dose? ,[object Object],[object Object],[object Object],[object Object],[object Object]
The right daily dose is different for every person, it’s the level to be achieved that is the same, just like thyroid or estrogen. ,[object Object],[object Object],[object Object],[object Object],[object Object]
Vitamin D Toxicity and why the FDA’s not crazy ,[object Object],[object Object],[object Object],[object Object]
Vitamin D Toxicity and why the FDA’s not crazy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
D Hormone and D receptors: multilayered complexity ,[object Object],[object Object],[object Object],[object Object]
The D is not the only sleep chemical, dopamine runs the sleep ,[object Object],[object Object],[object Object],[object Object],[object Object]
Other common presentations linked to D hormone deficiency ,[object Object],[object Object],[object Object],[object Object],[object Object]
Other supporting factors ,[object Object],[object Object],[object Object],[object Object]
My Basic Sleep Concepts ,[object Object],[object Object],[object Object],[object Object]
Now what do I do? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Our healthy vitamin D future

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Vitamin d and cardiology

  • 1. Sleep, Vitamins and Cardiovascular Disease Dr. Stasha Gominak ETMC Neurologic Institute, 700 Olympic Plaza, 912 Tyler, TX (903) 596-3808 www.drgominak.com 1/14/2011
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  • 11. The Migraine “Brainstem Generator” is in the same area of the brainstem where we do timing and paralysis of sleep
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  • 17. Why does everyone and his brother seem to have Sleep Apnea? Did we make it up? Has it always been there or is it new? What’s causing it? Why is it more in “developed countries”?
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  • 19. I thought Sleep Apnea only happened to fat people
  • 20. Does obesity cause sleep apnea or does sleep apnea cause obesity?
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  • 25. What’s happening here that’s goofing up my patients’ sleep? Periaquiductal gray
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  • 29. Vitamin D receptors concentrate in 3 brain areas; periaquiductal grey, lateral ventricles and pituitary/hypothalamus
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  • 31. In the 1970’s- 80’s Dr. Walter Stumpf “explained” what D hormone does
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  • 46. What does this D have to do with what I do in Cardiology?
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