This document discusses the history of vaccination and key figures in vaccine development. It describes how Robert Koch identified specific pathogens and established criteria for linking microbes to disease. Louis Pasteur created the first vaccines for rabies and anthrax. Edward Jenner developed the smallpox vaccine and coined the term "vaccine" based on his discovery that cowpox protected against smallpox. Emil von Behring discovered the diphtheria antitoxin to treat that disease in children. Alexandre Yersin identified the bacillus that causes bubonic plague. The introduction of penicillin by Alexander Fleming in 1928 led to widespread antibiotic use, while Edward Jenner replaced variolation with safer vaccination for small

1. Vaccination History
Julia Kimlinger

2. Robert Koch (1843-1910)
He is known for his identification of the specific causative
agents of many different illnesses/disease. He also gave
support for the idea of infectious disease. His findings led
to the creation of “Koch’s postulates”. It is four
generalized principles that link microorganisms to disease.

3. Louis Pasteur (1822-1895)
He created the first vaccinations for rabies and anthrax. His
discoveries have saved many people’s lives to this day. These
discoveries help support the germ theory.

4. Edward Jenner (1749-1823)
He helped create the vaccination for smallpox and helped
create the name vaccine. He created and described the
protective effect of cowpox against smallpox.

5. Emil von behring (1854-1917)
He discovered the diphtheria antitoxin. Diphtheria was the
major cause of death in children in the past.

6. Alexandre yersin (1863-1943)
He was one of the people who discovered the bacillus
responsible for the bubonic plague.

7. The introduction of penicillin
In 1928 Alexander Fleming discovered penicillin. His
discovery lead to the introduction of antibiotics. This
introduction is a milestone in the pharmaceutical chemistry.

8. The introduction of variolation
Variolation was created, but after awhile of using it Jenner
replaced it with a safer method known as vaccinations. This
change occurred in 1789.