The Center for Pediatric Genomic Medicine at Children's Mercy Hospital was established in 2011 to provide genomic sequencing and analysis for children to diagnose rare genetic diseases. It has diagnosed over 15 conditions in 25 families using exome sequencing, often changing medical management. For some cases, it has identified new treatment options like stem cell transplantation that have cured patients. The center aims to provide a genomic diagnosis within a day for babies in the NICU and within a month for all children to guide care and reduce unnecessary testing.