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Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence).
These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. By controlling the enzyme, Tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis.
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Lariago (Generic Chloroquine Phosphate tablets) is used for the suppressive treatment and for the treatment of acute attacks of Malaria. This medicine is also used for the treatment of extraintestinal amebiasis, amoebic hepatitis and abscess, discoid and systemic lupus erythematosus and rheumatoid arthritis.
Off-Label indications include the treatment of corona virus disease 2019 (COVID-19) and severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) infection.
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Tadalafil is a prescription medication which is FDA-approved to treat the following in men: erectile dysfunction (ED), a condition in which you can’t get or keep an erection, symptoms of benign prostatic hyperplasia (BPH), a prostate condition that may cause problems with urination and ED and symptoms of BPH together.
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Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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Hot Selling Organic intermediates
Ursodeoxycholic acid film coated tablets pil, taj pharmaceuticals.
1. Ursodeoxy cholic Acid 300mg Film-Coated Tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Ursodeoxy cholic Acid Dosage & Rx Info | Ursodeoxycholic Acid Uses, Side Effects – Antifungal/ Antibacterial, Ursodeoxycholic Acid 300mg Film-Coated Tablets: Indications, Side Effects, Warnings, Ursodeoxycholic Acid - Drug Information - Taj Pharma, Ursodeoxycholic Acid dose Taj pharmaceuticals Ursodeoxycholic Acid interactions, Taj Pharmaceutical Ursodeoxy cholic Acid contraindications, Ursodeoxycholic Acid price, Ursodeoxycholic A cid , Taj Pharma Ursodeoxy cholic Acid 300mg Film-Coated Tablets, - Taj Pharma . Stay connected t o all updated on Ursodeoxycholic Acid Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
URSODEOXYCHOLIC ACID
FILM COATED TABLETS
300 MG
Package leaflet: Information for the
patient
Ursodeoxycholic Acid Film Coated Tablets.
Read all of this leaflet carefully before you
start taking this medicine because it
contains important information for you.
- Keep this leaflet. You may need to read it
again.
- If you have any further questions, ask your
doctor or pharmacist.
- This medicine has been prescribed for you
only. Do not pass it on to others. It may
harm them, even if their signs of illness are
the same as yours.
- If any of the side effects gets serious, or if
you notice any side effects not listed in this
leaflet, please tell your doctor.
What is in this leaflet
1. What Ursodeoxycholic Acid Tablets is and
what it is used for
2. Before you are given Ursodeoxycholic
Acid Tablets
3. How you will be given Ursodeoxycholic
Acid Tablets
4. Possible side effects
5. How Ursodeoxycholic Acid Tablets is
stored
6. Further Information
1. What Ursodeoxycholic Acid Tablets
is and what it is used for
The active ingredient in
Ursodeoxycholic Acid Tablets is
ursodeoxycholic acid, which is a
naturally occurring substance (bile acid)
normally present in the bile.
Ursodeoxycholic Acid Tablets may be
used for the following:
• To dissolve certain types of gall stones
(stones in the gall bladder), which
contain cholesterol. Ursodeoxycholic
Acid Tablets may be suitable for
patients who are unable to have surgery
or do not wish to have surgery.
• To treat a type of liver disease known
as primary biliary cirrhosis (PBC).
• To treat liver disease associated with
cystic fibrosis in children aged 6 years to
less than 18 years.
2. Before you are given
Ursodeoxycholic Acid Tablets
Do not take Ursodeoxycholic Acid
Tablets if you:
• are pregnant, planning to become
pregnant or are breastfeeding
or if you have:
• ever had an allergic reaction to bile
acids or to any of the other ingredients
in Ursodeoxycholic Acid Tablets (see
'What Ursodeoxycholic Acid Tablets
Contain' in section 6 'Further
Information')
• a gall bladder which is not working
properly or you have gall-stones that
contain calcium
• severe liver disease other than primary
biliary cirrhosis
• peptic ulcers
• inflammation of the bowel
• inflammation of the gall bladder or
biliary tract (the ducts that transport bile
from the liver to the small intestine)
• blockage of the biliary tract
• frequent episodes of biliary colic (often
characterised by upper right stomach
pain).
If any of the above statements apply to
you, do not take Ursodeoxycholic Acid
Tablets.
Children aged 6 years to less than 18
years with cystic fibrosis
Not to be taken if the child has had
unsuccessful surgery to restore the flow
of bile to the small intestine.
Taking other medicines
Taking another medicine while you are
taking Ursodeoxycholic Acid Tablets can
affect how it or the other medicine
works. Please inform your doctor or
pharmacist if you are taking or have
recently taken any other medicines,
including those you may have bought
yourself without a prescription.
Please check with your doctor if you are
taking any of the following (or any other
medication):
• oral contraceptives (the pill) or
oestrogen (a female sex hormone)
• medicines used to lower blood
cholesterol (clofibrate, colestipol and
2. Ursodeoxy cholic Acid 300mg Film-Coated Tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Ursodeoxy cholic Acid Dosage & Rx Info | Ursodeoxycholic Acid Uses, Side Effects – Antifungal/ Antibacterial, Ursodeoxycholic Acid 300mg Film-Coated Tablets: Indications, Side Effects, Warnings, Ursodeoxycholic Acid - Drug Information - Taj Pharma, Ursodeoxycholic Acid dose Taj pharmaceuticals Ursodeoxycholic Acid interactions, Taj Pharmaceutical Ursodeoxy cholic Acid contraindications, Ursodeoxycholic Acid price, Ursodeoxycholic A cid , Taj Pharma Ursodeoxy cholic Acid 300mg Film-Coated Tablets, - Taj Pharma . Stay connected t o all updated on Ursodeoxycholic Acid Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
colestyramine). If it is necessary to take a
medicine containing colestipol or
colestyramine, you must take it at least 2
hours before or after Ursodeoxycholic
Acid Tablets
• medicines used to treat stomach
problems (charcoal and antacids
containing aluminium). If it is necessary
to take one of these medicines, you
must take it at least 2 hours before or
after Ursodeoxycholic Acid Tablets
• ciclosporin (used after transplants)
• ciprofloxacin (used to treat infections)
• nitrendipine (used to treat high blood
pressure)
• dapsone (used to treat leprosy and
other skin conditions).
If you have any doubts about whether
you should take this medicine then
discuss matters with your doctor before
taking it.
Pregnancy and breast-feeding
You should not take Ursodeoxycholic
Acid Tablets if you are pregnant or
trying to become pregnant.
You should use extra contraceptive
precautions that do not contain
hormones (e.g. condoms, caps or certain
coils) whilst taking Ursodeoxycholic
Acid Tablets (but see precautions above
in “Taking other medicines” section).
If at any point during treatment with
Ursodeoxycholic Acid Tablets you think
you might have become pregnant,
contact your doctor immediately.
You should not breast-feed whilst
taking Ursodeoxycholic Acid Tablets.
Driving and operating machines
Ursodeoxycholic Acid Tablets do not
affect the ability to drive or operate
machinery.
Important information for patients
who have an intolerance to some
sugars
If you have been told by your doctor
that you have an intolerance to some
sugars, contact your doctor before
taking this medicinal product, as it
contains lactose.
3. How you will be given
Ursodeoxycholic Acid Tablets
Your doctor will decide the dose which
is best for you. Always follow your
doctor’s instructions completely and
also follow any special instructions or
warnings which appear on the label
which the pharmacist has put on the
package. If you do not understand, or
are in any doubt, ask your doctor or
pharmacist.
Unless instructed differently, take your
tablets with a drink of water.
During treatment you should have
regular blood tests to check your liver
function.
Adults and Elderly
To dissolve gall stones that contain
cholesterol
The usual daily dose is one to three
tablets depending on your weight,
either in divided doses or as a single
night time dose.
Your doctor may tell you to take
Ursodeoxycholic Acid Tablets for up to
two years depending on the size of your
gall-stone. You should continue your
treatment for three months after your
stone appears to have gone.
To treat primary biliary cirrhosis
The usual daily dose is two to four
tablets, depending on your weight, to
be taken in two to four divided doses.
Children
The dose for a child may be less than the
usual adult dose. The doctor will
calculate the dose depending on the
child's weight.
For children with cystic fibrosis aged 6
years to less than 18 years
The dose will be calculated by the
doctor depending on the child's weight.
If you take more Ursodeoxycholic
Acid Tablets than you should
Too many Ursodeoxycholic Acid Tablets
may cause diarrhoea. If you accidentally
take too many tablets contact your
doctor, pharmacist or nearest hospital
casualty department. Take this leaflet
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and any remaining tablets with you to
show the doctor or pharmacist.
If you miss a dose of Ursodeoxycholic
Acid Tablets
If you forget to take a dose, take another
as soon as you remember. If it is almost
time for your next dose, then do not
take the missed dose at all. Do not take
a double dose to make up for a
forgotten tablet.
Stopping Ursodeoxycholic Acid
Tablets
You should continue to take
Ursodeoxycholic Acid Tablets for as long
as your doctor tells you to. Do not stop
taking the medicine without talking to
your doctor first.
4. Possible Side Effects
Like many medicines Ursodeoxycholic
Acid Tablets may cause side effects in
some patients, although not everybody
gets them.
The following side effects are common
(affect less than 1 out of 10 people):
• pasty stools
• diarrhoea.
The following side effects are very rare
(affect less than 1 out of 10,000 people):
• severe right upper stomach pain
• worsening of liver disease
• a red, itchy rash ('hives').
The following side effects may also
occur (how often these side effects
occur is not known):
• feeling sick
• being sick
• itching.
Very rarely gall-stones get a layer of
calcium on them, which may mean you
will need an operation to remove them.
Reporting of side effects
If you get any side effects, talk to your
doctor, pharmacist or nurse. This
includes any possible side effects not
listed in this leaflet. By reporting side
effects you can help provide more
information on the safety of this
medicine.
5. How Ursodeoxycholic Acid Tablets
is stored
Keep out of the reach and sight of
children.
Do not take this medicine if the expiry
date on the label has passed. The expiry
date refers to the last day of that month.
Ursodeoxycholic Acid Tablets should
not be taken if they show signs of
deterioration. Do not store above 25°C.
Store in the original container or
package in order to protect from light
and moisture. Do not transfer the
tablets to another container.
Medicines should not be disposed of via
wastewater or household waste. Ask
your pharmacist how to dispose of
medicines no longer required. These
measures will help to protect the
environment.
6. Further information
What Ursodeoxycholic Acid Tablets
contains
The active ingredient in
Ursodeoxycholic Acid Tablets is
ursodeoxycholic acid. Each tablet
contains 300mg.
The other ingredients are lactose, maize
starch, povidone, sodium starch
glycollate, magnesium stearate,
hydroxypropylmethylcellulose (E464),
titanium dioxide (E171), polyethylene
glycol and purified water.
What Ursodeoxycholic Acid Tablets
looks like and contents of the pack
The tablets are white, film-coated, have
a curved shape.
Ursodeoxycholic Acid Tablets are
available in polyethylene/polypropylene
(plastic) containers containing 60, 100 or
500 tablets and in blister strips of 60
tablets in cartons.
Not all pack sizes may be marketed.
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Manufactured in India by:
TAJ PHARMACEUTICALS LTD.
Mumbai, India
At: 615, GIDC, Kerala, Bavla, Dist.
Ahmedabad 438225, Gujarat, INDIA
This leaflet was last revised in July 2019