QUININE SULFATE - Drug Information - Taj Pharma, QUININE SULFATE dose Taj pharmaceuticals QUININE SULFATE interactions, Taj Pharmaceutical QUININE SULFATE contraindications, QUININE SULFATE price, QUININE SULFATE Taj Pharma QUININE SULFATE TABLETS 200mg SMPC- Taj Pharma . Stay connected to all updated on QUININE SULFATE Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Crizotinib Capsules 200mg, 250mg Taj Pharma PILTajPharmaQC
Crizotinib 200mg/250mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Crizotinib Dosage & Rx Info | Crizotinib Uses, Side Effects Crizotinib: Indications, Side Effects, Warnings, Crizotinib -Drug Information –Taj Pharma, Crizotinib dose Taj pharmaceuticals Crizotinib interactions, Taj Pharmaceutical Crizotinib contraindications, Crizotinib price, Crizotinib Taj Pharma Crizotinib SmPC-Taj Pharma Stay connected to all updated on Crizotinib Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Paracetamol and ibuprofen 500 mg and 150 mg film coated tablets smpc taj pha...Taj Pharma
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Cinnarizine 15 mg tablets smpc taj pharmaceuticalsTaj Pharma
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Nifedipine 30 mg prolonged release tablets smpc taj pharmaceuticalsTaj Pharma
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Vildagliptin Tablets 50mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Vildagliptin Dosage & Rx Info | Vildagliptin Uses, Side Effects Vildagliptin: Indications, Side Effects, Warnings, Vildagliptin -Drug Information –Taj Pharma, Vildagliptin dose Taj pharmaceuticals Vildagliptin interactions, Taj Pharmaceutical Vildagliptin contraindications, Vildagliptin price, Vildagliptin Taj Pharma Vildagliptin SmPC-Taj Pharma Stay connected to all updated on Vildagliptin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Piroxicam 20mg capsules smpc taj pharmaceuticalsTaj Pharma
Piroxicam Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Piroxicam Dosage & Rx Info | Piroxicam Uses, Side Effects -: Indications, Side Effects, Warnings, Piroxicam - Drug Information - Taj Pharma, Piroxicam dose Taj pharmaceuticals Piroxicam interactions, Taj Pharmaceutical Piroxicam contraindications, Piroxicam price, Piroxicam Taj Pharma Piroxicam 20mg Capsules SMPC- Taj Pharma . Stay connected to all updated on Piroxicam Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Crizotinib Capsules 200mg, 250mg Taj Pharma PILTajPharmaQC
Crizotinib 200mg/250mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Crizotinib Dosage & Rx Info | Crizotinib Uses, Side Effects Crizotinib: Indications, Side Effects, Warnings, Crizotinib -Drug Information –Taj Pharma, Crizotinib dose Taj pharmaceuticals Crizotinib interactions, Taj Pharmaceutical Crizotinib contraindications, Crizotinib price, Crizotinib Taj Pharma Crizotinib SmPC-Taj Pharma Stay connected to all updated on Crizotinib Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Paracetamol and ibuprofen 500 mg and 150 mg film coated tablets smpc taj pha...Taj Pharma
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Cinnarizine 15 mg tablets smpc taj pharmaceuticalsTaj Pharma
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Nifedipine 30 mg prolonged release tablets smpc taj pharmaceuticalsTaj Pharma
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Vildagliptin Tablets 50mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Vildagliptin Dosage & Rx Info | Vildagliptin Uses, Side Effects Vildagliptin: Indications, Side Effects, Warnings, Vildagliptin -Drug Information –Taj Pharma, Vildagliptin dose Taj pharmaceuticals Vildagliptin interactions, Taj Pharmaceutical Vildagliptin contraindications, Vildagliptin price, Vildagliptin Taj Pharma Vildagliptin SmPC-Taj Pharma Stay connected to all updated on Vildagliptin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Piroxicam 20mg capsules smpc taj pharmaceuticalsTaj Pharma
Piroxicam Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Piroxicam Dosage & Rx Info | Piroxicam Uses, Side Effects -: Indications, Side Effects, Warnings, Piroxicam - Drug Information - Taj Pharma, Piroxicam dose Taj pharmaceuticals Piroxicam interactions, Taj Pharmaceutical Piroxicam contraindications, Piroxicam price, Piroxicam Taj Pharma Piroxicam 20mg Capsules SMPC- Taj Pharma . Stay connected to all updated on Piroxicam Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Nicorandil Tablets BP 10mg, 20mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Nicorandil Dosage & Rx Info | Nicorandil Uses, Side Effects Nicorandil: Indications, Side Effects, Warnings, Nicorandil -Drug Information –Taj Pharma, Nicorandil dose Taj pharmaceuticals Nicorandil interactions, Taj Pharmaceutical Nicorandil contraindications, Nicorandil price, Nicorandil Taj Pharma Nicorandil SmPC-Taj Pharma Stay connected to all updated on Nicorandil Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Ifosfamide for Injection USP Taj Pharma SmPCTajPharmaQC
Ifosfamide for Injection USP 100mg, 500mg, 1000mg, and 2000mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Ifosfamide Dosage & Rx Info | Ifosfamide Uses, Side Effects Ifosfamide: Indications, Side Effects, Warnings, Ifosfamide -Drug Information –Taj Pharma, Ifosfamide dose Taj pharmaceuticals Ifosfamide interactions, Taj Pharmaceutical Ifosfamide contraindications, Ifosfamide price, Ifosfamide Taj Pharma Ifosfamide SmPC-Taj Pharma Stay connected to all updated on Ifosfamide Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Generic Fenofibrate Tablets (Fenolip, Lipicard, Tgr) are used as an adjunct to diet and other non-pharmacological treatment (e.g. exercise, weight reduction) for treatment of severe hypertriglyceridaemia with or without low HDL cholesterol, mixed hyperlipidaemia when a statin is contraindicated or not tolerated and mixed hyperlipidaemia in patients at high cardiovascular risk in addition to a statin when triglycerides and HDL cholesterol are not adequately controlled.
Fenofibrate Capsules SmPC Taj PharmaceuticalsTajPharmaQC
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Diazepam Injection USP 10mg/2ml, 50mg/10ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Diazepam Dosage & Rx Info | Diazepam Uses, Side Effects Diazepam: Indications, Side Effects, Warnings, Diazepam -Drug Information –Taj Pharma, Diazepam dose Taj pharmaceuticals Diazepam interactions, Taj Pharmaceutical Diazepam contraindications, Diazepam price, Diazepam Taj Pharma Diazepam SmPC-Taj Pharma Stay connected to all updated on Diazepam Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Fenofibrate 160 mg tablets smpc taj pharmaceuticalsTaj Pharma
Fenofibrate Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Fenofibrate Dosage & Rx Info | Fenofibrate Uses, Side Effects -: Indications, Side Effects, Warnings, Fenofibrate - Drug Information - Taj Pharma, Fenofibrate dose Taj pharmaceuticals Fenofibrate interactions, Taj Pharmaceutical Fenofibrate contraindications, Fenofibrate price, Fenofibrate Taj Pharma Fenofibrate 160 mg Tablets. SMPC- Taj Pharma . Stay connected to all updated on Fenofibrate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Clozapine Tablets USP 25mg, 50mg and 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Clozapine Dosage & Rx Info | Clozapine Uses, Side Effects Clozapine: Indications, Side Effects, Warnings, Clozapine -Drug Information –Taj Pharma, Clozapine dose Taj pharmaceuticals Clozapine interactions, Taj Pharmaceutical Clozapine contraindications, Clozapine price, Clozapine Taj Pharma Clozapine SmPC-Taj Pharma Stay connected to all updated on Clozapine Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Simvastatin Tablets USP Taj Pharma SmPCTajPharmaQC
Simvastatin Tablets USP 20mg, 40mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Simvastatin Dosage & Rx Info | Simvastatin Uses, Side Effects Simvastatin: Indications, Side Effects, Warnings, Simvastatin-Drug Information –Taj Pharma, Simvastatin dose Taj pharmaceuticals Simvastatin interactions, Taj Pharmaceutical Simvastatin contraindications, Simvastatin price, Simvastatin Taj Pharma Simvastatin SmPC-Taj Pharma Stay connected to all updated on Simvastatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Aripiperazole Tablets SmPC Taj PharmaceuticalsTajPharmaQC
Aripiprazole Tablets 10mg, 15mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Aripiprazole Dosage & Rx Info | Aripiprazole Uses, Side Effects Aripiprazole: Indications, Side Effects, Warnings, Aripiprazole -Drug Information –Taj Pharma, Aripiprazole dose Taj pharmaceuticals Aripiprazole interactions, Taj Pharmaceutical Aripiprazole contraindications, Aripiprazole price, Aripiprazole Taj Pharma Aripiprazole SmPC- Taj Pharma Stay connected to all updated on Aripiprazole Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Ranitidine 150mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
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Daunorubicin 20mg powder for i.v. injection smpc taj pharmaceuticalsTaj Pharma
DAUNORUBICIN - Drug Information - Taj Pharma, DAUNORUBICIN dose Taj pharmaceuticals DAUNORUBICIN interactions, Taj Pharmaceutical DAUNORUBICIN contraindications, DAUNORUBICIN price, DAUNORUBICIN Taj Pharma Cancer, oncologyDaunorubicin 20mg Powder for I.V. Injection SMPC- Taj Pharma . Stay connected to all updated on DAUNORUBICIN Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Sofosbuvir/Velpatasvir Tablets Taj Pharma SmPCTajPharmaQC
Sofosbuvir/Velpatasvir Tablets 400mg/100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Sofosbuvir/Velpatasvir Dosage & Rx Info | Sofosbuvir/Velpatasvir Uses, Side Effects Sofosbuvir/Velpatasvir: Indications, Side Effects, Warnings, Sofosbuvir/Velpatasvir -Drug Information –Taj Pharma, Sofosbuvir/Velpatasvir dose Taj pharmaceuticals Sofosbuvir/Velpatasvir interactions, Taj Pharmaceutical Sofosbuvir/Velpatasvir contraindications, Sofosbuvir/Velpatasvir price, Sofosbuvir/Velpatasvir Taj Pharma Sofosbuvir/Velpatasvir SmPC-Taj Pharma Stay connected to all updated on Sofosbuvir/Velpatasvir Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Fluorouracil 50mgml injection smpc taj pharmaceuticalsTaj Pharma
FLUOROURACIL Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, FLUOROURACIL Dosage & Rx Info | FLUOROURACIL Uses, Side Effects -: Indications, Side Effects, Warnings, FLUOROURACIL - Drug Information - Taj Pharma, FLUOROURACIL dose Taj pharmaceuticals FLUOROURACIL interactions, Taj Pharmaceutical FLUOROURACIL contraindications, FLUOROURACIL price, FLUOROURACIL Taj Pharma Cancer, oncologyFluorouracil 50mg/ml Injection. SMPC- Taj Pharma
Everolimus Tablets 5mg, 10mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Everolimus Dosage & Rx Info | Everolimus Uses, Side Effects Everolimus: Indications, Side Effects, Warnings, Everolimus -Drug Information –Taj Pharma, Everolimus dose Taj pharmaceuticals Everolimus interactions, Taj Pharmaceutical Everolimus contraindications, Everolimus price, Everolimus Taj Pharma Everolimus SmPC-Taj Pharma Stay connected to all updated on Everolimus Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Ibuprofen 400 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
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Vemurafenib 240 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
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Nicorandil Tablets BP 10mg, 20mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Nicorandil Dosage & Rx Info | Nicorandil Uses, Side Effects Nicorandil: Indications, Side Effects, Warnings, Nicorandil -Drug Information –Taj Pharma, Nicorandil dose Taj pharmaceuticals Nicorandil interactions, Taj Pharmaceutical Nicorandil contraindications, Nicorandil price, Nicorandil Taj Pharma Nicorandil SmPC-Taj Pharma Stay connected to all updated on Nicorandil Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Ifosfamide for Injection USP Taj Pharma SmPCTajPharmaQC
Ifosfamide for Injection USP 100mg, 500mg, 1000mg, and 2000mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Ifosfamide Dosage & Rx Info | Ifosfamide Uses, Side Effects Ifosfamide: Indications, Side Effects, Warnings, Ifosfamide -Drug Information –Taj Pharma, Ifosfamide dose Taj pharmaceuticals Ifosfamide interactions, Taj Pharmaceutical Ifosfamide contraindications, Ifosfamide price, Ifosfamide Taj Pharma Ifosfamide SmPC-Taj Pharma Stay connected to all updated on Ifosfamide Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Generic Fenofibrate Tablets (Fenolip, Lipicard, Tgr) are used as an adjunct to diet and other non-pharmacological treatment (e.g. exercise, weight reduction) for treatment of severe hypertriglyceridaemia with or without low HDL cholesterol, mixed hyperlipidaemia when a statin is contraindicated or not tolerated and mixed hyperlipidaemia in patients at high cardiovascular risk in addition to a statin when triglycerides and HDL cholesterol are not adequately controlled.
Fenofibrate Capsules SmPC Taj PharmaceuticalsTajPharmaQC
Fenofibrate Capsules 160mg, 200mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Fenofibrate Dosage & Rx Info | Fenofibrate Uses, Side Effects Fenofibrate: Indications, Side Effects, Warnings, Fenofibrate -Drug Information –Taj Pharma, Fenofibrate dose Taj pharmaceuticals Fenofibrate interactions, Taj Pharmaceutical Fenofibrate contraindications, Fenofibrate price, Fenofibrate Taj Pharma Fenofibrate SmPC- Taj Pharma Stay connected to all updated on Fenofibrate Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Diazepam Injection USP 10mg/2ml, 50mg/10ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Diazepam Dosage & Rx Info | Diazepam Uses, Side Effects Diazepam: Indications, Side Effects, Warnings, Diazepam -Drug Information –Taj Pharma, Diazepam dose Taj pharmaceuticals Diazepam interactions, Taj Pharmaceutical Diazepam contraindications, Diazepam price, Diazepam Taj Pharma Diazepam SmPC-Taj Pharma Stay connected to all updated on Diazepam Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Fenofibrate 160 mg tablets smpc taj pharmaceuticalsTaj Pharma
Fenofibrate Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Fenofibrate Dosage & Rx Info | Fenofibrate Uses, Side Effects -: Indications, Side Effects, Warnings, Fenofibrate - Drug Information - Taj Pharma, Fenofibrate dose Taj pharmaceuticals Fenofibrate interactions, Taj Pharmaceutical Fenofibrate contraindications, Fenofibrate price, Fenofibrate Taj Pharma Fenofibrate 160 mg Tablets. SMPC- Taj Pharma . Stay connected to all updated on Fenofibrate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Clozapine Tablets USP 25mg, 50mg and 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Clozapine Dosage & Rx Info | Clozapine Uses, Side Effects Clozapine: Indications, Side Effects, Warnings, Clozapine -Drug Information –Taj Pharma, Clozapine dose Taj pharmaceuticals Clozapine interactions, Taj Pharmaceutical Clozapine contraindications, Clozapine price, Clozapine Taj Pharma Clozapine SmPC-Taj Pharma Stay connected to all updated on Clozapine Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Simvastatin Tablets USP Taj Pharma SmPCTajPharmaQC
Simvastatin Tablets USP 20mg, 40mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Simvastatin Dosage & Rx Info | Simvastatin Uses, Side Effects Simvastatin: Indications, Side Effects, Warnings, Simvastatin-Drug Information –Taj Pharma, Simvastatin dose Taj pharmaceuticals Simvastatin interactions, Taj Pharmaceutical Simvastatin contraindications, Simvastatin price, Simvastatin Taj Pharma Simvastatin SmPC-Taj Pharma Stay connected to all updated on Simvastatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Aripiperazole Tablets SmPC Taj PharmaceuticalsTajPharmaQC
Aripiprazole Tablets 10mg, 15mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Aripiprazole Dosage & Rx Info | Aripiprazole Uses, Side Effects Aripiprazole: Indications, Side Effects, Warnings, Aripiprazole -Drug Information –Taj Pharma, Aripiprazole dose Taj pharmaceuticals Aripiprazole interactions, Taj Pharmaceutical Aripiprazole contraindications, Aripiprazole price, Aripiprazole Taj Pharma Aripiprazole SmPC- Taj Pharma Stay connected to all updated on Aripiprazole Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Ranitidine 150mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Ranitidine Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Ranitidine Dosage & Rx Info | Ranitidine Uses, Side Effects -: Indications, Side Effects, Warnings, Ranitidine - Drug Information - Taj Pharma, Ranitidine dose Taj pharmaceuticals Ranitidine interactions, Taj Pharmaceutical Ranitidine contraindications, Ranitidine price, Ranitidine Taj Pharma Ranitidine 150mg Film-coated TabletsSMPC- Taj Pharma . Stay connected to all updated on Ranitidine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Daunorubicin 20mg powder for i.v. injection smpc taj pharmaceuticalsTaj Pharma
DAUNORUBICIN - Drug Information - Taj Pharma, DAUNORUBICIN dose Taj pharmaceuticals DAUNORUBICIN interactions, Taj Pharmaceutical DAUNORUBICIN contraindications, DAUNORUBICIN price, DAUNORUBICIN Taj Pharma Cancer, oncologyDaunorubicin 20mg Powder for I.V. Injection SMPC- Taj Pharma . Stay connected to all updated on DAUNORUBICIN Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Sofosbuvir/Velpatasvir Tablets Taj Pharma SmPCTajPharmaQC
Sofosbuvir/Velpatasvir Tablets 400mg/100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Sofosbuvir/Velpatasvir Dosage & Rx Info | Sofosbuvir/Velpatasvir Uses, Side Effects Sofosbuvir/Velpatasvir: Indications, Side Effects, Warnings, Sofosbuvir/Velpatasvir -Drug Information –Taj Pharma, Sofosbuvir/Velpatasvir dose Taj pharmaceuticals Sofosbuvir/Velpatasvir interactions, Taj Pharmaceutical Sofosbuvir/Velpatasvir contraindications, Sofosbuvir/Velpatasvir price, Sofosbuvir/Velpatasvir Taj Pharma Sofosbuvir/Velpatasvir SmPC-Taj Pharma Stay connected to all updated on Sofosbuvir/Velpatasvir Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Fluorouracil 50mgml injection smpc taj pharmaceuticalsTaj Pharma
FLUOROURACIL Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, FLUOROURACIL Dosage & Rx Info | FLUOROURACIL Uses, Side Effects -: Indications, Side Effects, Warnings, FLUOROURACIL - Drug Information - Taj Pharma, FLUOROURACIL dose Taj pharmaceuticals FLUOROURACIL interactions, Taj Pharmaceutical FLUOROURACIL contraindications, FLUOROURACIL price, FLUOROURACIL Taj Pharma Cancer, oncologyFluorouracil 50mg/ml Injection. SMPC- Taj Pharma
Everolimus Tablets 5mg, 10mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Everolimus Dosage & Rx Info | Everolimus Uses, Side Effects Everolimus: Indications, Side Effects, Warnings, Everolimus -Drug Information –Taj Pharma, Everolimus dose Taj pharmaceuticals Everolimus interactions, Taj Pharmaceutical Everolimus contraindications, Everolimus price, Everolimus Taj Pharma Everolimus SmPC-Taj Pharma Stay connected to all updated on Everolimus Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Ibuprofen 400 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Ibuprofen Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Ibuprofen Dosage & Rx Info | Ibuprofen Uses, Side Effects -: Indications, Side Effects, Warnings, Ibuprofen - Drug Information - Taj Pharma, Ibuprofen dose Taj pharmaceuticals Ibuprofen interactions, Taj Pharmaceutical Ibuprofen contraindications, Ibuprofen price, Ibuprofen Taj Pharma Ibuprofen 400 mg film-coated tablets SMPC- Taj Pharma . Stay connected to all updated on Ibuprofen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Vemurafenib 240 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Vemurafenib Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Vemurafenib Dosage & Rx Info | Vemurafenib Uses, Side Effects -: Indications, Side Effects, Warnings, Vemurafenib - Drug Information - Taj Pharma, Vemurafenib dose Taj pharmaceuticals Vemurafenib interactions, Taj Pharmaceutical Vemurafenib contraindications, Vemurafenib price, Vemurafenib Taj Pharma Vemurafenib 240mg Film Coated Tablets SMPC- Taj Pharma . Stay connected to all updated on Vemurafenib Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Qutipin (Generic Quetiapine Fumarate Tablets) is used for treating schizophrenia, bipolar disorder, recurrent major depressive disorder (MDD) and generalised anxiety disorder (GAD).
Multivitamin capsules smpc taj pharmaceuticalsTaj Pharma
MULTIVITAMIN CAPSULES Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, MULTIVITAMIN CAPSULES Dosage & Rx Info | MULTIVITAMIN CAPSULES Uses, Side Effects -: Indications, Side Effects, Warnings, MULTIVITAMIN CAPSULES - Drug Information - Taj Pharma, MULTIVITAMIN CAPSULES dose Taj pharmaceuticals MULTIVITAMIN CAPSULES interactions, Taj Pharmaceutical MULTIVITAMIN CAPSULES contraindications, MULTIVITAMIN CAPSULES price, MULTIVITAMIN CAPSULES Taj Pharma MULTIVITAMIN CAPSULES SMPC- Taj Pharma . Stay connected to all updated on MULTIVITAMIN CAPSULES Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Venlafaxine 75mg tablets smpc taj pharmaceuticalsTaj Pharma
Venlafaxine Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Venlafaxine Dosage & Rx Info | Venlafaxine Uses, Side Effects -: Indications, Side Effects, Warnings, Venlafaxine - Drug Information - Taj Pharma, Venlafaxine dose Taj pharmaceuticals Venlafaxine interactions, Taj Pharmaceutical Venlafaxine contraindications, Venlafaxine price, Venlafaxine Taj Pharma Venlafaxine 75mg tablets SMPC- Taj Pharma . Stay connected to all updated on Venlafaxine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Terbinafine 250mg tablets smpc taj pharmaceuticalsTaj Pharma
Terbinafine Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Terbinafine Dosage & Rx Info | Terbinafine Uses, Side Effects -: Indications, Side Effects, Warnings, Terbinafine - Drug Information - Taj Pharma, Terbinafine dose Taj pharmaceuticals Terbinafine interactions, Taj Pharmaceutical Terbinafine contraindications, Terbinafine price, Terbinafine Taj Pharma Terbinafine 250mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Terbinafine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Griseofulvin 500mg tablets smpc taj pharmaceuticalsTaj Pharma
Griseofulvin - Drug Information - Taj Pharma, Griseofulvin dose Taj pharmaceuticals Griseofulvin interactions, Taj Pharmaceutical Griseofulvin contraindications, Griseofulvin price, Griseofulvin Taj Pharma Griseofulvin 500mg TabletsSMPC- Taj Pharma . Stay connected to all updated on Griseofulvin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Ranitidine is a gastro-intestinal agent that inhibits histamine H2 receptors.
The histamine H2 receptor antagonist ranitidine is used to treat erosive esophagitis, Zollinger-Ellison syndrome, gastric ulcers, GERD, and duodenal ulcers.
Micafungin for Injection Taj Pharma SmPCTajPharmaQC
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Quinine sulfate 200mg tablets smpc taj pharmaceuticals
1. QUININE SULFATE TABLETS 200mg SM PC, Taj Phar mac euticals
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RX
QUININE SULFATE
TABLETS
200MG
1.NAME OF THE MEDICINAL PRODUCT
Quinine Sulfate 200mg Tablets.
2. QUALITATIVE AND QUANTITATIVE
COMPOSITION
Each tablet contains 200mg Quinine Sulfate.
For the full list of excipients, see section 6.1.
3. PHARMACEUTICAL FORM
Film-coated tablet.
White, circular, biconvex film-coated tablets.
4. CLINICAL PARTICULARS
4.1 Therapeutic indications
1) Treatment of falciparum (malignant tertian)
malaria.
2) Treatment and prevention of nocturnal leg
cramps in adults and the elderly, when cramps
cause regular disruption of sleep (see section 4.2
and section 4.4).
4.2 Posology and method of administration
Posology
For the treatment of falciparum (malignant
tertian) malaria:
Adults (including elderly) and children aged 12
years and over: 600mg every eight hours for 7
days. The dose may depend upon the size of the
patient, severity of infection, and evidence of
renal or liver disease (when the intervals should
be increased), due to a prolonged half-life of the
drug.
If quinine resistance is known or suspected on
completion of the course additional treatment
may be given. This may be one of the following:
1. doxycycline 200mg daily (as a single dose or
in 2 divided doses) for at least 7 days.
2. clindamycin 300mg four times daily for 5
days.
Children aged 10-12 years: 10mg/kg every eight
hours for 7 days.
Children under 10 years: Not recommended
For the treatment and prevention of nocturnal
leg cramps:
Adults (including elderly):
The recommended dose is 200mg at bedtime.
The maximum dose is 300mg.
A reduction in frequency of leg cramps may take
up to 4 weeks to become apparent. Patients
should be monitored closely during the early
stages of treatment for adverse effects. After an
initial trial of 4 weeks, treatment should be
stopped if there is no benefit. Treatment should
be interrupted at approximately three monthly
intervals to assess the need for continuation of
treatment with quinine.
Method of Administration
For oral administration.
4.3 Contraindications
• Hypersensitivity to the active substance or to
any of the excipients listed in section 6.1.
• Haemolysis or Haemoglobinuria
• Optic neuritis
• Tinnitus
• Myasthenia gravis, quinine may cause severe
respiratory distress and dysphagia in these
patients.
• As quinine has been implicated in precipitating
blackwater fever, it is generally contraindicated
in patients who have already suffered an attack.
4.4 Special Warnings and precautions for use
Cinochonism
• Administration of quinine may give rise to
cinchonism, which is generally more severe in
overdose, but may also occur in normal
therapeutic doses. Patients should be warned not
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to exceed the prescribed dose, because of the
possibility of serious, irreversible side effects in
overdose. Treatment for night cramps should be
stopped if symptoms of cinchonism emerge.
Such symptoms include tinnitus, impaired
hearing, headache, nausea, and disturbed vision
(see sections 4.8 and 4.9).
Hypersensitivity
• Hypersensitivity to quinine may also occur
with symptoms of cinchonism together with
urticaria, flushing, pruritus, rash, fever,
angioedema, dyspnoea and asthma.
• Serious hypersensitivity reactions including
Stevens-Johnson syndrome have been reported
with quinine.
Cardiac disorders
• Quinine has dose-dependent QT-prolonging
effects. Caution is recommended in patients with
conditions which predispose to QT-prolongation
and in patients with atrioventricular block.
Quinine should be used with caution in patients
with atrial fibrillation, heart block, other cardiac
conduction defects, or other serious heart
disease. Quinine may cause
hypoprothrombinaemia and enhance the effects
of anticoagulants.
Glucose-6-Phosphate Dehydrogenase (G-6-PD)
Deficiency
• Quinine has been implicated in precipitating
blackwater fever when given for prolonged
periods, although in some cases, glucose-6-
phosphate dehydrogenase deficiency may have
been involved. Patients with glucose-6-
phosphate dehydrogenase deficiency may be at
increased risk of haemolysis during quinine
therapy and may develop acute haemolytic
anaemia.Quinine should not be withheld from
pregnant women who have life threatening
malaria (see section 4.6).
• Treatment with quinine should be monitored in
case signs of resistance develop.
• Before use for nocturnal leg cramps, the risks,
which include significant adverse effects and
interactions (see above and Sections 4.5 and
4.8), should be carefully considered relative to
the potential benefits. These risks are likely to be
of particular concern in the elderly. Quinine
should only be considered when cramps are very
painful or frequent, when other treatable causes
of cramp have been ruled out, and when non-
pharmacological measures have not worked.
Quinine sulfate should not be used for this
indication during pregnancy (see Section 4.6).
• Quinine may cause unpredictable serious and
life-threatening thrombocytopenia, which is
thought to be an idiosyncratic hypersensitivity
reaction. Quinine should not be prescribed or
administered to patients who have previously
experienced any adverse reaction to quinine,
including that in tonic water or other beverages.
Patients should be instructed to stop treatment
and consult a physician if signs of
thrombocytopenia such as unexplained bruising
or bleeding occur.
• Reduce the dosage (or increase intervals
between doses) in renal or hepatic disease.
4.5 Interaction with other medicinal products
and other forms of interaction
Effect of other drugs on Quinine
Quinine is metabolised via hepatic oxidative
cytochrome P450 pathways, predominantly by
CYP3A4. There is the potential for increased
Quinine toxicity with concurrent use of potent
CYP3A4 inhibitors, which include azole
antifungal drugs and HIV protease inhibitors.
Sub-optimal Quinine serum levels may result
from concomitant use of CYP3A4 inducers,
which include rifampicin, barbiturates,
carbamazepine and phenytoin. Care should be
taken when Quinine is used in combination with
other CYP3A4 substrates, especially those
causing prolongation of the QT interval.
Caution is advised when administering quinine
with drugs which could prolong the QT interval.
Quinine may increase the levels of phenobarbital
and of carbamazepine. Patients should be
monitored closely during concomitant use of
quinine with these agents.
Effect of Quinine on other drugs
The plasma concentration of flecanide, digoxin
and mefloquine may be increased.
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Amantadine: Quinine can reduce the renal
clearance of amantadine with risk of amantadine
toxicity (including headache, nausea, dizziness).
Analgesics: increased risk of ventricular
arrhythmias with levacetylmethadol (avoid
concomitant use).
Ciclosporin: Quinine can decrease serum plasma
concentrations of ciclosporin.
Cardiac glycosides: Quinine increases plasma
concentrations of cardiac glycosides and reduced
dosage of concomitant cardiac glycosides such
as digoxin to half the maintenance dose may be
necessary.
Other drug interactions
There is an increased risk of ventricular
arrhythmias with other drugs which prolong the
QT interval, including amiodarone,
moxifloxacin, pimozide, thioridzine and
halofantrine.
Antiarrhythmics: Concomitant use of
amiodarone should be avoided due to the
increased risk of ventricular arrhythmias. The
plasma concentration of flecainide is increased
by quinine. Concomitant use of quinidine may
increase the possibility of cinchonism.
Antibacterials: There is an increased risk of
ventricular arrhythmias when moxifloxacin is
given with quinine. Rifampicin can reduced the
serum levels of quinine, therefore reducing its
therapeutic effect.
Anticoagulants: Quinine may cause
hypoprothrombinaemia and enhance the effects
of anticoagulants.
Caution is advised when administering quinine
with drugs which could prolong the QT interval.
Antihistamines: Concomitant use of astemizole
and terfenadine should be avoided due to the
increased risk of ventricular arrhythmias.
Antimalarials: There may be an increased risk of
side effects if quinine is used with other
antimalarials, for example, chloroquine,
halofantrine and mefloquine (increased risk of
convulsions), although this should not prevent
their use in severe cases. Quinine may increase
the plasma concentration of mefloquine.
Chloroquine and quinine appear to be
antagonistic when given together for P
falciparum malaria. There is an increased risk of
ventricular arrhythmias with
halofantrine.Antipsychotics: There is an
increased risk of ventricular arrhythmias and
concomitant use should be avoided with
pimozide or thioridazine.
Hypoglycaemics: There is an increased risk of
hypoglycaemia when taken concurrently.
Suxamethonium: Quinine enhances the
neuromuscular effects of suxamethonium.
Ulcer-healing drugs: Cimetidine inhibits
quinine metabolism leading to increased plasma-
quinine concentrations.
4.6 Fertility, Pregnancy and lactation
Pregnancy
Large doses of quinine can induce abortion.
Quinine may cause congenital abnormalities of
the CNS and extremities. Following
administration of large doses during pregnancy,
phototoxicity and deafness have been reported in
neonates. Quinine sulfate should not be used
during pregnancy unless the benefits outweigh
the risks.
Treatment of falciparium malaria: Pregnancy in
a patient with malaria is not generally regarded
as a contraindication to the use of quinine. As
malaria infection is potentially serious during
pregnancy and poses a threat to the mother and
foetus, there appears to be little justification in
withholding treatment in the absence of a
suitable alternative.
Prophylaxis of nocturnal leg-cramps: Quinine
sulfate should not be used during pregnancy to
treat cramps.
Breastfeeding
Quinine sulfate is excreted in breast milk, but no
problems in humans have been reported. .
Infants at risk for glucose-6-phosphate
dehydrogenase deficiency should not be breast-
fed until this disease can be ruled out. However,
quinine sulfate should not be given to nursing
mothers unless the benefits outweigh the risks.
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4.7 Effects on ability to drive and use
machines
Quinine may cause visual disturbances and
vertigo, hence patients should be advised that if
affected they should not drive or operate
machinery.
4.8 Undesirable Effects
dverse drug reactions are ranked by frequency,
the most frequent first, using the following
convention: very common (≥ 1/10); common (≥
1/100 to < 1/10); uncommon (≥ 1/1,000 to <
1/100); rare (≥ 1/10,000 to < 1/1,000); very rare
(< 1/10,000), not known (cannot be estimated
from the available data).
System Organ
Class
Adverse Drug Reaction
Frequency
Not Known
Blood and
lymphatic system
disorders
Thrombocytopenia, intravascular
coagulation,
hypoprothrombinaemia,
haemoglobinuria, haemolytic-
uremic syndrome, pancytopenia,
haemolysis agranulocytosis,
thrombocytopenic purpura.
Immune system
disorders
Eczematous dermatitis, oedema,
erythema, lichen planus,
hypersensitivity reactions
(asthma, angioneurotic oedema,
photosensitivity, hot and flushed
skin, fever, pruritis,
thrombocytopenic purpura and
urticaria).
Metabolism and
nutrition
disorders
Hypoglycaemia.
Psychiatric
disorders
Agitation, confusion.
Nervous system
disorders
Headache, vertigo, excitement,
loss of consciousness, coma,
death.
Eye disorders Blurred vision, defective colour
perception, visual field
constriction.
Ear and labyrinth
disorders
Tinnitus, impaired hearing.
Cardiac disorders Atrioventricular conduction
disturbances, a fall in blood
pressure coupled with a feeble
pulse, prolongation of the QT
interval, widening of the QRS
complex, T wave flattening.
Respiratory,
thoracic and
mediastinal
disorders
Bronchospasm, dyspnoea.
Gastrointestinal
disorders
Diarrhoea, nausea, vomiting,
abdominal pain*.
Skin and
subcutaneous
tissue disorders
Flushing, rash, urticaria,
eczematous dermatitis, oedema,
erythema, lichen planus, pruritis,
photosensitivity, Stevens-
Johnson syndrome.
Musculoskeletal
and connective
tissue disorders
Muscle weakness, aggravation of
Myasthenia gravis
Renal and
urinary disorders
Renal insufficiency, acute renal
failure (may be due to an
immune mechanism or to
circulatory failure), oliguria.
Reproductive
system and breast
disorders
Abortion**
General disorders
and
administration
site conditions
Cinchonism***
* May occur after long term administration of
quinine.
** Toxic doses of quinine may induce abortion,
but it is unwise to withhold the drug if less toxic
antimalarials are not available.
*** More common in overdose, but may occur
even after normal doses of quinine. In its mild
form symptoms include tinnitus, impaired
hearing, rashes, headache, nausea and disturbed
vision. Its more severe manifestations symptoms
may include gastrointestinal symptoms,
oculotoxicity, CNS disturbances, cardiotoxicity
and death (see section 4.9). Visual disorders
(blurred vision, defective colour perception,
visual field constriction and total blindness).
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after
authorisation of the medicinal product is
important. It allows continued monitoring of the
benefit/risk balance of the medicinal product.
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4.9 Overdose
Acute intoxication can be seen after ingestion of
doses of 4-12g, but a dose of 8g can prove
lethal. The average fatal dose for an adult is
about 8g although deaths have been reported
from as little as 1.5g in an adult and 900mg in a
child.
Symptoms: Quinine overdosage may lead to
serious side effects including irreversible visual
loss, and can be fatal.
Symptoms include vomiting, tinnitus, deafness,
headache, vasodilation and visual disturbance.
Features of a significant overdose include
convulsions, impairment of consciousness,
respiratory depression, QT prolongation,
ventricular arrhythmia, cardiogenic shock and
renal failure. High doses of quinine are
teratogenic and may cause miscarriage.
Hypokalaemia and hypoglycaemia may also
occur.
Treatment: Children (< 5 years) who have
ingested any amount should be referred to
hospital. Older children and adults should be
referred to hospital if more than 30 mg/kg of
quinine base has been taken.
Each 200 mg tablet is equivalent to 165 mg
quinine base, each 300 mg tablet is equivalent to
248 mg quinine base.
Consider activated charcoal (50 g for adults; 1
g/kg for children) if the patient presents within 1
hour of ingestion of more than 30 mg/kg quinine
base or any amount in a child under 5 years.
Multiple dose activated charcoal will enhance
quinine elimination.
Observe patients for at least 12 hours after
ingestion. Monitor cardiac conduction and
rhythm, serum electrolytes, blood glucose and
visual acuity.
Other treatment is symptomatic to maintain
blood pressure, respiration, renal function and to
treat arrhythmia, convulsions, hypoglycaemia
and acidosis.
5. PHARMACOLOGICAL PROPERTIES
5.1 Pharmacodynamic properties
Pharmacotherpeutic group: Quinine alkaloid.
Quinine is a cinchona alkaloid and a 4-
methanolquinoline antimalarial agent which is a
rapidly acting blood schizontocide with activity
against Plasmodium falciparum, P vivax, P
ovale and P malariae. It is active against the
gametocytes of P malariae and P vivax, but not
against mature gametocytes of P falciparum.
Since it has no activity against exoerythrocytic
forms, quinine does not produce a radical cure in
vivax or ovale malarias.
Pharmacodynamnic effect
Quinine has effects on the motor end-plate of
skeletal muscle and prolongs the refractory
period. Like quinidine, quinine is a sodium
channel blocker and, therefore, has local
anaesthetic, and both anti- and proarrhythmic
activity.
Mechanism of action
The precise mechanism of action of quinine is
unclear but it may interfere with lysosome
function or nucleic acid synthesis in the malaria
parasite.
5.2 Pharmacokinetic properties
The pharmacokinetics of quinine are altered
significantly by malaria infection, the major
effects being reductions in both its apparent
volume of distribution and its clearance.
Absorption:
Quinine is rapidly and almost completely
absorbed from the GI tract and peak
concentrations in the circulation are attained
about 1-3 hours after oral administration of the
sulfate.
Distribution:
Plasma protein binding is about 70% in healthy
subjects and rises to 90% or more in patients
with malaria.
Quinine is widely distributed throughout the
body. Concentrations attained in the CSF of
patients with cerebral malaria have been
reported to be about 2-7% of those in the
plasma.
Biotransformation:
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Quinine is extensively metabolised in the liver
and rapidly excreted mainly in the urine.
Estimates of the proportion of unchanged
quinine excreted in the urine vary from less than
5% to 20%. The pharmacokinetics of quinine are
altered significantly by malaria infection, with
reductions in both the apparent volume of
distribution and clearance.
Elimination:
Excretion is increased in acid urine. The
elimination half-life is about 11 hours in healthy
subjects but may be prolonged in patients with
malaria. Small amounts of quinine also appear in
the bile and saliva.
Quinine crosses the placenta and is excreted in
the breast milk.
5.3 Preclinical safety data
Not applicable.
6. PHARMACEUTICAL PARTICULARS
6.1 List of excipients
The tablets also contain:
Sodium lauryl sulfate
Povidone
Microcrystalline cellulose (E460)
Croscarmellose sodium
Magnesium stearate
Hydrogenated vegetable oil
The coating contains:
Hypromellose
Hydroxypropyl Cellulose
Medium Chain Triglycerides
Macrogol 3350
Titanium Dioxide (E171)
6.2 Incompatibilities
None known.
6.3 Shelf life
Shelf-life
A three year shelf life is claimed and our
marketed products includes a three year expiry
date.
Shelf-life after dilution/reconstitution
Not applicable.
Shelf-life after first opening
Not applicable.
6.4 Special precautions for storage
Store below 25°C in a dry place.
6.5 Nature and contents of container
The product containers are rigid injection
moulded polypropylene or injection blow-
moulded polyethylene tablet containers with
polyfoam wad or polyethylene ullage filler and
snap-on polyethylene lids; in case any supply
difficulties should arise the alternative is amber
glass bottles with screw caps and polyfoam wad
or cotton wool.
The product may also be supplied in blister
packs in cartons:
a) Carton: Printed carton manufactured from
white folding box board.
b) Blister pack: (i) 250µm white rigid PVC. (ii)
Surface printed 20µm hard temper aluminium
foil with 5-7g/M² PVC and PVdC compatible
heat seal lacquer on the reverse side.
Pack sizes: 28s, 30s, 56s, 60s, 84s, 90s, 100s,
112s, 120s, 168s, 180s 250s, 500s, 1000s.
Product may also be supplied in bulk packs, for
reassembly purposes only, in polybags contained
in tins, skillets or polybuckets filled with
suitable cushioning material. Bulk packs are
included for temporary storage of the finished
product before final packaging into the proposed
marketing containers.
Maximum size of bulk packs: 25,000.
Not all pack sizes may be marketed
6.6 Special precautions for disposal and other
handling
Not applicable.
7. MANUFACTURER:
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Manufactured in India by:
TAJ PHARMACEUTICALS LTD.
Mumbai, India
At: 615, GIDC, Kerala, Bavla, Dist. Ahmedabad
438225, Gujarat, INDIA