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Drug counseling points in hypertension
Drug category Pharmacist role
Diuretics  Monitor for muscle weakness, confusion, dizziness.
 Ensure patient participation in dose modulation.
 Select appropriate dose timing to avoid frequent urination in the night.
 Explain about the possibility of drug interactions with ACE inhibitors.
Beta blockers  Monitor for hypotension, dizziness, headache, and bradycardia.
 Educate regarding possibility of nocturnal dreams, impotence and CNS problems.
 Explain the need for dose tapering before stopping the drug
ACE inhibitors  Monitor for hypotension, dizziness, cough, taste disturbances and rash.
Alpha blockers  Monitor for hypotension.
 Patients on Gastro Intestinal Therapeutic System (GITS) preparation should be told not to
crush/chew the tablets
Drug counseling points in Diabetes
Drug category Pharmacist role
Sulfonylureas  Explain the methods to prevent, detect and manage hypoglycemia.
 Monitor for symptoms of jaundice.
 Discuss the administration time in relation to food and need for alcohol abstinence, ask for
history of sulfur sensitivity
Insulin  Explain the methods to prevent, detect and manage hypoglycemia.
 Educate the patient regarding newer insulin administration techniques, proper storage
conditions for insulin.
 Ask the patient to carry chocolates or other sweets during travel and ask him not to miss the
meals
Metformin  Advice the patient to take with/after food.
 Monitor for muscle pain, unusual sleepiness, nausea, stomach pain, weight loss.
Thiazolidinediones  Take history of liver problems; monitor the patients for yellow discoloration of urine.
 Monitor the patient for peripheral edema
Acarbose  Encourage the patient to take it with the first bite of food.
 Monitor for abdominal pain and cramps.
 Advice the patient not to take sucrose (Sugar) during hypoglycemic attack as it may not be
absorbed when acarbose is taken
Drug counseling points in coronary heart disease
Drug category Pharmacist role
Beta-blockers  Monitor for hypotension, dizziness, headache, and bradycardia.
 Educate the patient regarding possibility of nocturnal dreams and CNS problems.
 Explain the need for dose tapering before stopping the drug.
Nitrates  Sublingual administration, sublingual tablets should not be chewed or crushed, use of
transdermal patches, do not stand up immediately while using this medication.
 Monitor for bluish colored lips, fingernails or palms
Aspirin  Encourage the patient to take drug with food.
 Monitor for abdominal pain, tarry stools, fever, spitting of blood.
 In case of enteric-coated preparations, ask the patient not to crush or chew the tablets.
Drug counseling points in dyslipidemia
Drug category Pharmacist role
Statins  Educate the patient to take these drugs after food.
 It is advisable to take these medications during night (except for atorvastatin).
 Ask the patient to report to the doctor if any signs of muscle pain appear
Fibrates  Take with or immediately after food to lessen stomach upset.
 Monitor for blood in urine, chest pain, and shortness of breath, stomach pain.
Anion exchange
resins
 This medicine should never be taken in dry form.
 Mix the medicine with beverage or drinks.
 Monitor for stomach pain, nausea, and vomiting, belching, bloating, diarrhea
Nicotinic acid
derivatives
 Do not crush, break or chew the extended release medication.
 Monitor for darkening of urine, loss of appetite, severe stomach pain, and yellow eyes
Drug counseling points in asthma
Drug category Pharmacist role
Beta receptor agonists  Short acting drugs belonging to this category should be used mainly for
symptom relief.
 Patients on long acting drugs should be told that the medication may take some
time period to show the action.
 Patient also needs monitoring for tremors and muscle pain.
Theophylline  patients on sustained release preparations should be told not to crush/chew the
tablets
Anticholinergics  Monitor for dry throat, nausea, headache, blurred vision, and painful
urination
Corticosteroids  Medications should be administered regularly.
 They should not be stopped abruptly.
 It needs dose tapering before stopping.
 Emphasize gargling of mouth after use of inhaled medications
Mast cell stabilizers  Patient should be told that this medication is used to prevent the asthma attack
and it does not relieve bronchospasm that has already started.
Drug counseling points in epilepsy
Drug category Pharmacist role
Barbiturates  Explain the patient about the possibility of dependence.
 Explain the possibility of drug interactions especially with oral contraceptives.
 Monitor for fever, skin rashes, swelling of eyelids, mental depression
Benzodiazepines  Monitor for behavior problems, mental depression, impaired memory, skin rash.
 Explain to the patient regarding the drug interaction.
 Monitor for symptoms of overdose.
Hydantoins
(Phenytoin)
 The patient should be advised not to stop the medicine or take other medicine without the
doctor’s advice.
 Explain to the patients the various symptoms of overdose.
 Monitor for gum bleeding, bone malformations, headache, and joint pain, learning problems
in children.
 Patients should be explained regarding the drug interaction potential of the drug
Valproates  Controlled release and sustained release preparations should not be chewed or crushed.
 They should be swallowed whole
Succinimides  This should be taken with food or milk so as to reduce the stomach upset.
 Patients should be advised to give their medication history before undergoing surgery as this
drug can potentiate the CNS effect of anesthetics
Drug counseling points in rheumatoid arthritis
Drug category Pharmacist role
Methotrexate  Monitor for back pain, dark urine, drowsiness, headache, yellow colored urine.
 Advice not to take alcohol.
 Take pregnancy history before initiation of the drug.
 Ask the patient to consult the doctor before taking NSAIDs.
Non-Steroidal
Anti
Inflammatory
Drugs (NSAIDs)
 Monitor for abdominal pain, tarry stools, fever, spitting of blood.
 Ask the patient to take the drug with full glass of water and mention not to lie down for 15-
30 minutes after taking the medicine.
 Advice the patient to take this medicine with food.
Cyclooxygenase-2
(COX-2)
inhibitors
 Monitor for dark colored stool.
 Advise the patient to take the medicine after food so as to reduce the stomach irritation.
Corticosteroids  Advise the patient to take with food.
 Monitor for blurred vision, frequent urination, confusion, excitement, and infection at
injection site.
 Take diabetic history before initiation of the drug.
 Explain to the patient about dose tapering.
 Warn against missing of doses.
Reference
British National Formulary 61 2021 compiled by Habtamu.A
For further information
MCH building ground floor PHONE no +251118134245 email, dis@sphmmc.edu.et t.me/sphmmcdic

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Today

  • 1. November 12/2021 Drug counseling points in hypertension Drug category Pharmacist role Diuretics  Monitor for muscle weakness, confusion, dizziness.  Ensure patient participation in dose modulation.  Select appropriate dose timing to avoid frequent urination in the night.  Explain about the possibility of drug interactions with ACE inhibitors. Beta blockers  Monitor for hypotension, dizziness, headache, and bradycardia.  Educate regarding possibility of nocturnal dreams, impotence and CNS problems.  Explain the need for dose tapering before stopping the drug ACE inhibitors  Monitor for hypotension, dizziness, cough, taste disturbances and rash. Alpha blockers  Monitor for hypotension.  Patients on Gastro Intestinal Therapeutic System (GITS) preparation should be told not to crush/chew the tablets
  • 2. Drug counseling points in Diabetes Drug category Pharmacist role Sulfonylureas  Explain the methods to prevent, detect and manage hypoglycemia.  Monitor for symptoms of jaundice.  Discuss the administration time in relation to food and need for alcohol abstinence, ask for history of sulfur sensitivity Insulin  Explain the methods to prevent, detect and manage hypoglycemia.  Educate the patient regarding newer insulin administration techniques, proper storage conditions for insulin.  Ask the patient to carry chocolates or other sweets during travel and ask him not to miss the meals Metformin  Advice the patient to take with/after food.  Monitor for muscle pain, unusual sleepiness, nausea, stomach pain, weight loss. Thiazolidinediones  Take history of liver problems; monitor the patients for yellow discoloration of urine.  Monitor the patient for peripheral edema Acarbose  Encourage the patient to take it with the first bite of food.  Monitor for abdominal pain and cramps.  Advice the patient not to take sucrose (Sugar) during hypoglycemic attack as it may not be absorbed when acarbose is taken
  • 3. Drug counseling points in coronary heart disease Drug category Pharmacist role Beta-blockers  Monitor for hypotension, dizziness, headache, and bradycardia.  Educate the patient regarding possibility of nocturnal dreams and CNS problems.  Explain the need for dose tapering before stopping the drug. Nitrates  Sublingual administration, sublingual tablets should not be chewed or crushed, use of transdermal patches, do not stand up immediately while using this medication.  Monitor for bluish colored lips, fingernails or palms Aspirin  Encourage the patient to take drug with food.  Monitor for abdominal pain, tarry stools, fever, spitting of blood.  In case of enteric-coated preparations, ask the patient not to crush or chew the tablets. Drug counseling points in dyslipidemia Drug category Pharmacist role Statins  Educate the patient to take these drugs after food.  It is advisable to take these medications during night (except for atorvastatin).  Ask the patient to report to the doctor if any signs of muscle pain appear Fibrates  Take with or immediately after food to lessen stomach upset.  Monitor for blood in urine, chest pain, and shortness of breath, stomach pain. Anion exchange resins  This medicine should never be taken in dry form.  Mix the medicine with beverage or drinks.  Monitor for stomach pain, nausea, and vomiting, belching, bloating, diarrhea Nicotinic acid derivatives  Do not crush, break or chew the extended release medication.  Monitor for darkening of urine, loss of appetite, severe stomach pain, and yellow eyes
  • 4. Drug counseling points in asthma Drug category Pharmacist role Beta receptor agonists  Short acting drugs belonging to this category should be used mainly for symptom relief.  Patients on long acting drugs should be told that the medication may take some time period to show the action.  Patient also needs monitoring for tremors and muscle pain. Theophylline  patients on sustained release preparations should be told not to crush/chew the tablets Anticholinergics  Monitor for dry throat, nausea, headache, blurred vision, and painful urination Corticosteroids  Medications should be administered regularly.  They should not be stopped abruptly.  It needs dose tapering before stopping.  Emphasize gargling of mouth after use of inhaled medications Mast cell stabilizers  Patient should be told that this medication is used to prevent the asthma attack and it does not relieve bronchospasm that has already started.
  • 5. Drug counseling points in epilepsy Drug category Pharmacist role Barbiturates  Explain the patient about the possibility of dependence.  Explain the possibility of drug interactions especially with oral contraceptives.  Monitor for fever, skin rashes, swelling of eyelids, mental depression Benzodiazepines  Monitor for behavior problems, mental depression, impaired memory, skin rash.  Explain to the patient regarding the drug interaction.  Monitor for symptoms of overdose. Hydantoins (Phenytoin)  The patient should be advised not to stop the medicine or take other medicine without the doctor’s advice.  Explain to the patients the various symptoms of overdose.  Monitor for gum bleeding, bone malformations, headache, and joint pain, learning problems in children.  Patients should be explained regarding the drug interaction potential of the drug Valproates  Controlled release and sustained release preparations should not be chewed or crushed.  They should be swallowed whole Succinimides  This should be taken with food or milk so as to reduce the stomach upset.  Patients should be advised to give their medication history before undergoing surgery as this drug can potentiate the CNS effect of anesthetics
  • 6. Drug counseling points in rheumatoid arthritis Drug category Pharmacist role Methotrexate  Monitor for back pain, dark urine, drowsiness, headache, yellow colored urine.  Advice not to take alcohol.  Take pregnancy history before initiation of the drug.  Ask the patient to consult the doctor before taking NSAIDs. Non-Steroidal Anti Inflammatory Drugs (NSAIDs)  Monitor for abdominal pain, tarry stools, fever, spitting of blood.  Ask the patient to take the drug with full glass of water and mention not to lie down for 15- 30 minutes after taking the medicine.  Advice the patient to take this medicine with food. Cyclooxygenase-2 (COX-2) inhibitors  Monitor for dark colored stool.  Advise the patient to take the medicine after food so as to reduce the stomach irritation. Corticosteroids  Advise the patient to take with food.  Monitor for blurred vision, frequent urination, confusion, excitement, and infection at injection site.  Take diabetic history before initiation of the drug.  Explain to the patient about dose tapering.  Warn against missing of doses. Reference British National Formulary 61 2021 compiled by Habtamu.A For further information MCH building ground floor PHONE no +251118134245 email, dis@sphmmc.edu.et t.me/sphmmcdic