Typhoid fever is a life-threatening illness caused by the Salmonella Typhi bacterium. It affects approximately 12.5 million people worldwide each year. The disease is contracted through ingestion of contaminated food or water. Symptoms include sustained high fever, abdominal pain, diarrhea or constipation. While antibiotics have reduced the fatality rate to 1-2%, drug-resistant strains are an increasing problem. Vaccines can help prevent infection for those traveling to areas where the disease is common.
In this video, you can learn about the basics of Typhoid fever and also the symptoms and treatment of this disease in a very simple way. We describe to you here all about,
1. Typhoid fever
2. Symptoms of Typhoid
3. Causes of Typhoid
4. Diagnosis of Typhoid
5. Prevention of Typhoid
6. Treatment of Typhoid
7. Diet for Typhoid fever
You can download the PowerPoint file from below link:
https://docs.google.com/presentation/d/1s8Ix3t8t3O-KYWVze2C8nm4QYIWJdFSXg_sTR78htiQ/edit?usp=sharing
You can learn from video by the below link:
https://youtu.be/PDhr_UmTWuc
Typhoid, also known as Typhoid fever or Typhoid Disease , is a common worldwide
bacterial disease, transmitted by the ingestion of food or water contaminated with the
feces of an infected person, which contain the bacterium Salmonella enterica, serovar
Typhi(fig.1). The bacteria then perforate through the
intestinal wall and are phagocytosed by macrophages.
The organism is a Gram-negative short bacillus that is
motile due to its peritrichous flagella(fig.1). The
bacterium grows best at 37°C / 98.6°F – human body
temperature.
Bacteria of the genus Salmonella are highly adapted for growth in both humans and animals and cause a wide spectrum of disease.
The growth of S. Typhi and S. Paratyphi is restricted to human hosts, in whom these organisms cause enteric (typhoid) fever.
The remaining serotypes (non-typhoidal Salmonella or NTS) can colonize the gastrointestinal tracts of a broad range of animals, including mammals, reptiles, birds and insects.
Typhoid fever is the bacterial disease caused by the ingestion of food or water
contaminated with bacterium, Salmonella typhi. The typhoid fever is also called
typhoid. Typhoid fever is diagnosed by detection of Salmonella typhi in the stool
sample. Typhoid responds to anti-biotic treatment. Approximately (3-5) % of the
people becomes carrier after acute illness. Typhoid fever is gastric fever,
abdominal typhus, infantile remittent fever, slow fever, nervous fever and
pathogenic fever.
In this video, you can learn about the basics of Typhoid fever and also the symptoms and treatment of this disease in a very simple way. We describe to you here all about,
1. Typhoid fever
2. Symptoms of Typhoid
3. Causes of Typhoid
4. Diagnosis of Typhoid
5. Prevention of Typhoid
6. Treatment of Typhoid
7. Diet for Typhoid fever
You can download the PowerPoint file from below link:
https://docs.google.com/presentation/d/1s8Ix3t8t3O-KYWVze2C8nm4QYIWJdFSXg_sTR78htiQ/edit?usp=sharing
You can learn from video by the below link:
https://youtu.be/PDhr_UmTWuc
Typhoid, also known as Typhoid fever or Typhoid Disease , is a common worldwide
bacterial disease, transmitted by the ingestion of food or water contaminated with the
feces of an infected person, which contain the bacterium Salmonella enterica, serovar
Typhi(fig.1). The bacteria then perforate through the
intestinal wall and are phagocytosed by macrophages.
The organism is a Gram-negative short bacillus that is
motile due to its peritrichous flagella(fig.1). The
bacterium grows best at 37°C / 98.6°F – human body
temperature.
Bacteria of the genus Salmonella are highly adapted for growth in both humans and animals and cause a wide spectrum of disease.
The growth of S. Typhi and S. Paratyphi is restricted to human hosts, in whom these organisms cause enteric (typhoid) fever.
The remaining serotypes (non-typhoidal Salmonella or NTS) can colonize the gastrointestinal tracts of a broad range of animals, including mammals, reptiles, birds and insects.
Typhoid fever is the bacterial disease caused by the ingestion of food or water
contaminated with bacterium, Salmonella typhi. The typhoid fever is also called
typhoid. Typhoid fever is diagnosed by detection of Salmonella typhi in the stool
sample. Typhoid responds to anti-biotic treatment. Approximately (3-5) % of the
people becomes carrier after acute illness. Typhoid fever is gastric fever,
abdominal typhus, infantile remittent fever, slow fever, nervous fever and
pathogenic fever.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
43. Vaccinations 2 years 2 years 2 weeks N/A 1 Injection ViCPS (Typhim Vi, Pasteur Merieux) 5 years 6 years 2 weeks 2 days 4 1 capsule by mouth Ty21a (Vivotif Berna, Swiss Serum and Vaccine Institute) Booster needed every... Minimum age for vaccination Total time needed to set aside for vaccination Time between doses Number of doses necessary How given Vaccine Name
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