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THE PROTEINS ARE ESSENCIAL IN THE
NORMAL FUNCTION OF THE BODY:
Formed by amino-acids.
Some of their functions are:
•Enzymatic
•Hormones
•Structure
•Immunity
•Contraction
•Transportation
•Homeostasis
•Etc.
THE ABSENCE OF
SOME PROTEINS
ORIGINATE DIFFERENT
DISEASES
““SBP researchers identify molecularSBP researchers identify molecular
switch that controls genes needed toswitch that controls genes needed to
repair skeletal muscle”repair skeletal muscle”
  
 
IN MUSCULAR DISEASES
THE STEM CELLS OF THE
MUSCLE DON´T WORK
IT CAN´T REPAIR THE
NORMAL MUSCLE
DAMAGES
IT HAPPENS IN THE
DYSTROPHY, CANCER
AND AGING
““SBP researchers identify molecular switch thatSBP researchers identify molecular switch that
controls genes needed to repair skeletal muscle”controls genes needed to repair skeletal muscle”
Researches of
the Sanford
Burnham Prebys
Medical Research
Institute
Identify the TBP-
containing
TFIID-Protein
complex
These elements are
transcription factors,
they take part of the
pre- initiation complex
of the RNA
polymerase II
Important in
the muscle
regeneration
““SBP researchers identify molecular switchSBP researchers identify molecular switch
that controls genes needed to repairthat controls genes needed to repair
skeletal muscle”skeletal muscle”
The TBP-
containing
TFIID-Protein
complex
Molecular switches
To the genes of
the stem cells of
the muscle
““SBP researchers identify molecularSBP researchers identify molecular
switch that controls genes needed toswitch that controls genes needed to
repair skeletal muscle”repair skeletal muscle”
Although they show the essential task of the TBP-containing
TFIID-Protein complex , they also prove that the protein that were
being studying TBP2 is not important In the muscle regeneration,
the cells participate in the reparation process of the muscle without
the TBP2.
Are you
sure ??
OPINION
The dystrophies are not very common disease, but
the aging and the mutations such as the cancer are
so frequently in now days, this aspects carry me to
think that this research is going to be an important
topic in this time and in the future. The better thing
that a man could have is the life, be away from the
death, and it is the result of this investigation, it
gives hope of live to the men.
““Study identifies FGF21 protein asStudy identifies FGF21 protein as
potential therapeutic agent forpotential therapeutic agent for
cardiovascular diseases, type 2cardiovascular diseases, type 2
diabetes”diabetes”
 
Researches of Umeå
University showed how
the FGF21 redistribute
fatty acids by two ways
FGF21 is fibroblast grow factor , it´s member of an
endocrine subfamily
FGF21 is a potential
therapeutic element
to treat the obesity´s
diseases such as type
2 diabetes
““Study identifies FGF21 protein as potential therapeuticStudy identifies FGF21 protein as potential therapeutic
agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes”
““Study identifies FGF21 protein as potential therapeuticStudy identifies FGF21 protein as potential therapeutic
agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes”
LPL
Activated in
Muscle
Adipose tissue
Function
Hydrolytic cleavage
Uptake of blood
lipids
““Study identifies FGF21 protein as potential therapeuticStudy identifies FGF21 protein as potential therapeutic
agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes”
The objective of the investigation is to
gives tools to develop new treatments
to people that suffer obesity related
health problems, a treatment that
stimulates the LPL could reduce the
signs and symptoms of the diseases
type 2 diabetes and cardiovascular
problems.
OPINION
What do
you
think?
The obesity and the diseases related with this are common diseases in
now days, the men don´t learn to control themselves in the food and it´s
an investigation that help the humanity to fight against the trouble. The
medicine have to be updated in the world, and this is the evidence.
THE MOST IMPORTANT THING IN A
INVESTIGATION IS THE UTILITY THAT WE CAN
GIVE THEM IN THE REAL LIFE, IN THIS CASE IN
THE MEDICINE
MEDICAL UTILITY
MEDICAL UTILITY
A lot of people have fall in the mistake of eat and eat,
it´s the origin of the obesity´s diseases, that in this
time are very common, but here is the medicine, the
investigation, to give the a second opportunity to have
a better life style and enjoy in the short life. Our
science have to be updated and continue saving lives.
MEDICAL UTILITY
Like we have seen in this presentation, the
proteins are good options to treatments in
all the world, it´s a big support to the
medicine and the humanity, helping as to
find the cure to different and hard diseases
such as the cancer, dystrophies, obesity,
type 2 diabetes and cardiovascular troubles.
of this way the protein contributes to have a
better life each day (in some cases).
BIBLIOGRAPHY
· Umea University. Study identifies FGF21 protein as potential therapeutic agent for
cardiovascular diseases, type 2 diabetes [Internet]. News-Medical.net; 2016 [access
February 12 of 2016]. Avaible in: http://www.newsmedical.net/news/20160211/Study-
identifies-FGF21-protein-as-potential-therapeutic-agent-for-cardiovascular-diseases-
type-2-diabetes.aspx
Published on February 11, 2016
· Sanford-Burnham Prebys Medical Discover Institute. SBP researchers identify
molecular switch that controls genes needed to repair skeletal muscle [internet]. News-
Medical.net; 2016 [access February 12 of 2016]. Available in: http://www.news-
medical.net/news/20160211/SBP-researchers-identify-molecular-switch-that-controls-
genes-needed-to-repair-skeletal-muscle.aspx
Published on February 11, 2016
 
THE PROTEINS IN MEDICINE. MOLECULAR BIOLOGY

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THE PROTEINS IN MEDICINE. MOLECULAR BIOLOGY

  • 1.
  • 2.
  • 3.
  • 4. THE PROTEINS ARE ESSENCIAL IN THE NORMAL FUNCTION OF THE BODY: Formed by amino-acids. Some of their functions are: •Enzymatic •Hormones •Structure •Immunity •Contraction •Transportation •Homeostasis •Etc. THE ABSENCE OF SOME PROTEINS ORIGINATE DIFFERENT DISEASES
  • 5. ““SBP researchers identify molecularSBP researchers identify molecular switch that controls genes needed toswitch that controls genes needed to repair skeletal muscle”repair skeletal muscle”      IN MUSCULAR DISEASES THE STEM CELLS OF THE MUSCLE DON´T WORK IT CAN´T REPAIR THE NORMAL MUSCLE DAMAGES IT HAPPENS IN THE DYSTROPHY, CANCER AND AGING
  • 6. ““SBP researchers identify molecular switch thatSBP researchers identify molecular switch that controls genes needed to repair skeletal muscle”controls genes needed to repair skeletal muscle” Researches of the Sanford Burnham Prebys Medical Research Institute Identify the TBP- containing TFIID-Protein complex These elements are transcription factors, they take part of the pre- initiation complex of the RNA polymerase II Important in the muscle regeneration
  • 7. ““SBP researchers identify molecular switchSBP researchers identify molecular switch that controls genes needed to repairthat controls genes needed to repair skeletal muscle”skeletal muscle” The TBP- containing TFIID-Protein complex Molecular switches To the genes of the stem cells of the muscle
  • 8. ““SBP researchers identify molecularSBP researchers identify molecular switch that controls genes needed toswitch that controls genes needed to repair skeletal muscle”repair skeletal muscle” Although they show the essential task of the TBP-containing TFIID-Protein complex , they also prove that the protein that were being studying TBP2 is not important In the muscle regeneration, the cells participate in the reparation process of the muscle without the TBP2. Are you sure ??
  • 9. OPINION The dystrophies are not very common disease, but the aging and the mutations such as the cancer are so frequently in now days, this aspects carry me to think that this research is going to be an important topic in this time and in the future. The better thing that a man could have is the life, be away from the death, and it is the result of this investigation, it gives hope of live to the men.
  • 10. ““Study identifies FGF21 protein asStudy identifies FGF21 protein as potential therapeutic agent forpotential therapeutic agent for cardiovascular diseases, type 2cardiovascular diseases, type 2 diabetes”diabetes”   Researches of Umeå University showed how the FGF21 redistribute fatty acids by two ways FGF21 is fibroblast grow factor , it´s member of an endocrine subfamily FGF21 is a potential therapeutic element to treat the obesity´s diseases such as type 2 diabetes
  • 11. ““Study identifies FGF21 protein as potential therapeuticStudy identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes”
  • 12. ““Study identifies FGF21 protein as potential therapeuticStudy identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes” LPL Activated in Muscle Adipose tissue Function Hydrolytic cleavage Uptake of blood lipids
  • 13. ““Study identifies FGF21 protein as potential therapeuticStudy identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes”agent for cardiovascular diseases, type 2 diabetes” The objective of the investigation is to gives tools to develop new treatments to people that suffer obesity related health problems, a treatment that stimulates the LPL could reduce the signs and symptoms of the diseases type 2 diabetes and cardiovascular problems.
  • 14. OPINION What do you think? The obesity and the diseases related with this are common diseases in now days, the men don´t learn to control themselves in the food and it´s an investigation that help the humanity to fight against the trouble. The medicine have to be updated in the world, and this is the evidence.
  • 15. THE MOST IMPORTANT THING IN A INVESTIGATION IS THE UTILITY THAT WE CAN GIVE THEM IN THE REAL LIFE, IN THIS CASE IN THE MEDICINE
  • 17. MEDICAL UTILITY A lot of people have fall in the mistake of eat and eat, it´s the origin of the obesity´s diseases, that in this time are very common, but here is the medicine, the investigation, to give the a second opportunity to have a better life style and enjoy in the short life. Our science have to be updated and continue saving lives.
  • 18. MEDICAL UTILITY Like we have seen in this presentation, the proteins are good options to treatments in all the world, it´s a big support to the medicine and the humanity, helping as to find the cure to different and hard diseases such as the cancer, dystrophies, obesity, type 2 diabetes and cardiovascular troubles. of this way the protein contributes to have a better life each day (in some cases).
  • 19. BIBLIOGRAPHY · Umea University. Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes [Internet]. News-Medical.net; 2016 [access February 12 of 2016]. Avaible in: http://www.newsmedical.net/news/20160211/Study- identifies-FGF21-protein-as-potential-therapeutic-agent-for-cardiovascular-diseases- type-2-diabetes.aspx Published on February 11, 2016 · Sanford-Burnham Prebys Medical Discover Institute. SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle [internet]. News- Medical.net; 2016 [access February 12 of 2016]. Available in: http://www.news- medical.net/news/20160211/SBP-researchers-identify-molecular-switch-that-controls- genes-needed-to-repair-skeletal-muscle.aspx Published on February 11, 2016