This document outlines a proposed research and development agenda to address long-term global food needs. It notes that food production must double by 2050 and identifies several constraints and risks, including land and water scarcity, climate change, rising energy prices, and pollution. It proposes a new "ecologically intensive" agricultural model that increases yields sustainably using techniques like conservation agriculture and agroecology. Key elements of the proposed R&D agenda include soil health, integrated pest management, crop design, and landscape ecology. The development agenda calls for strategies to ensure food security, price stabilization, and increased agriculture infrastructure and education globally.