Besides the 4 fundamental forces established and accepted by current science community, a new force is to be added. This is the familiar mechanical force mediated by the particle 'Phonon'. A new discovery.
Discovery of Electricity
Early Discoveries
Particles of Matter
Electric Charge
Law of Conservation of Charge
Electric Force
Electrostatic Law
Static Electricity
Charging by Friction
Charging by Contact
Charging by Induction
JOURNEY OF THE UNIVERSE FROM BIRTH TO REBIRTH WITH INSIGHT INTO THE UNIFIED I...SURAJ KUMAR
In this paper it has been tried to propose a hypothesis for Universe life cycle from its birth to death along with a cyclic view into its rebirth referring to the concept of Cosmic Microwave Background Radiation, Spiral Structure of Galaxies and Spiral Structure of Elementary Particles. It has been tried to inherit the behaviour of Big Bang in consensus with the proposals of Steady State Cosmology within the vicinity of all modern ongoing researches. It also provides a unified approach for various force interactions of particles through the intrinsic behaviours of Spiral Structure of Elementary Particles. The inverse relation between mass of particle and rate of change of cross section of spiral arms gives us a distinct view of gravitational interactions. Also the orientation of the curl of spiral differentiate the electromagnetic interaction when has revolution and electroweak interaction when has rotational curl. Strong interaction can be described through the phase differences of particles with charge not in multiple of ½. This paper also describes the process for formation off composite particles and the atomic structure through various dynamics of interactions by spiral structured particles.
Discovery of Electricity
Early Discoveries
Particles of Matter
Electric Charge
Law of Conservation of Charge
Electric Force
Electrostatic Law
Static Electricity
Charging by Friction
Charging by Contact
Charging by Induction
JOURNEY OF THE UNIVERSE FROM BIRTH TO REBIRTH WITH INSIGHT INTO THE UNIFIED I...SURAJ KUMAR
In this paper it has been tried to propose a hypothesis for Universe life cycle from its birth to death along with a cyclic view into its rebirth referring to the concept of Cosmic Microwave Background Radiation, Spiral Structure of Galaxies and Spiral Structure of Elementary Particles. It has been tried to inherit the behaviour of Big Bang in consensus with the proposals of Steady State Cosmology within the vicinity of all modern ongoing researches. It also provides a unified approach for various force interactions of particles through the intrinsic behaviours of Spiral Structure of Elementary Particles. The inverse relation between mass of particle and rate of change of cross section of spiral arms gives us a distinct view of gravitational interactions. Also the orientation of the curl of spiral differentiate the electromagnetic interaction when has revolution and electroweak interaction when has rotational curl. Strong interaction can be described through the phase differences of particles with charge not in multiple of ½. This paper also describes the process for formation off composite particles and the atomic structure through various dynamics of interactions by spiral structured particles.
All classical search for the center of the universe tentatively ended with Newton. A new beginning of search based on Newton's laws of motion just began.
Question on the nature of the particle wave. de Broglie and other scientists struggled to find out but failed. Ended in the probability interpretation.
The nature of particle waves or de Broglie waves. Long forgotten and misinterpreted. Now true nature found and mathematically verified. More details: new-physics.com
On request from a friend - a journey that starts from Young's double split experiment and ends up with fundamental questions about the nature of reality and the essence of science...
A series of satellite projects to secure more and better images of the Cosmic Microwave Background (CMB) since 1980. Age of universe estimated to be 13.73 billion years.
CA 10.01 Discovery of CMB (Cosmic Microwave Background)Stephen Kwong
Discovery of Cosmic Microwave Background by Arno Penzias and Robert Wilson in the 1960s. Found to be the relic radiation from the beginning of the Universe. One of the greatest discovery in science history so far.
Relativity, Visonics, Classical physics on acceleration. Different results in different views. Relativity results in lengthy and complicated equations, almost unworkable. But in visonics, apparent acceleration = actual acceleration.
CA 5.11 Velocity Transform in Relativity & VisonicsStephen Kwong
The kinematic entity of velocity is transformed in the Theory of Relativity by the Lorentz transformation of frames; in visionics, by delayed images. Simpler results in visonics.
Cosmic Adventure 5.8 Time Dilation of Clocks in Motion in VisonicsStephen Kwong
Time dilation phenomenon for clocks on the move in visonics. The result is the same as clocks at rest since the speed of light is not affected by the motion of the source.
The concept of length contraction in traditional theory of Special Relativity. Although seemingly verified by many experiment, its reality still remains controversial and pending amendment.
Cosmic adventure 5.4 Moving Objects in VisonicsStephen Kwong
The visonic version of objects in motion. The approach is different from relativity and the results are also different. But they are all realistic and classical.
Cosmic Adventure 5.3 Frames in Motion in RelativityStephen Kwong
The Einstein way of transforming time and location by the Lorentz factor, marking the departure from Newtonian physics. But why is it so is not explained.
Cosmic Adventure 5.2 Visonic Transform Without MotionStephen Kwong
The case when v=0 not covered by Relativity. Delay timing happens normally in static cases. The static case leads to the universe in spatial and temporal layers.It is just the world we live in.
Cosmic Adventure 5.1 Relative Motion in Special RelativityStephen Kwong
The classical equations of relative motion are translated by the theory of Special Relativity into relativistic equations. The origin of the Lorentz factor recapitulated.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.