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Testing the impact of online brain
training in promoting wellbeing and
resilience
Dr Justine Gatt
Senior Research Fellow
Brain Dynamics Centre
University of Sydney Medical School & WMI
Westmead
The Problem
How to promote wellbeing and
resilience?
 In an effort to promote mental health, most

research in psychiatry focuses on understanding
mental illness, ways to predict it and treat it
 However, mental health is not simply the absence
of mental illness – only 25% commonality!
 The questions remain:
 What defines optimal mental health? What
defines the flourishing and resilient individual?
 Can these features be nurtured in people who
may be low in resilience and wellbeing using
intervention tools such as e-health platforms?
The Approach
The TWIN-E Study in
Emotional Wellbeing

Recruitment

Australian Twin Registry:
N approached = 9,622 //N double positive response = 2,370 (25%)

• 1600 twins
Phase I
• 18-65 years, healthy
• Tested across Australia
Web Assessment + DNA saliva kit (N = 1,643)
• Phase 1 & 2 tested for
behavior and brain function
MRI/fMRI/DTI
EEG
• Phase 3 involves a RCT
N = 270
N = 451
trial to 30-days of
Phase II: 12-months
MyBrainSolutions cognitive
training

Completed
in Mar 2012

Completed
in Oct 2013

Web Assessment (90% retention)

Phase III: e-health RCT

To be completed
in early 2014
Aim 2: Evaluate efficacy in improving
wellbeing & resilience using
MyBrainSolutions©
Games for
positivity, stress
reduction
attention, memory

Tools to track and
reward yourself

Assessment and
Report on your
own Brain Profile
The Results
MyBrainSolutions improves psychological
functioning over 30 days
2.4

Positive affect

Depressed mood

3.0

2.2

Control

2.8

Mean

Mean

2.0
1.8
1.6
1.4

2.6
2.4

1.2

2.2

1.0

2.0

Time 1

Time 2

Time 1

3.9

Emotion suppression

56.0

Social skills

55.5

3.7

55.0

Mean

Mean

Time 2

Pre-Post Treatment

Pre-Post Treatment

3.5

3.3

54.5
54.0
53.5

3.1

53.0

2.9

52.5
52.0

2.7

Time 1

Time 2

Pre-Post Treatment

Treatment

Time 1

Time 2

Pre-Post Treatment
Future studies: A new e-health tool
developed by Freedomsway
Meta-Analysis© for individuals

Vantage Point© for organisations
Potential Collaboration
What I can offer / What I need
 Collaborators interested in testing the

e-health platforms, Brain Resource’s
MyBrainSolutions or Freedomsway’s
Meta-Analysis in their own cohorts
 Collaborators interested in using our
new scales of wellbeing and
resilience for use in their own cohorts
New measures of wellbeing & resilience
 COMPAS-W Scale of Wellbeing: 26-item composite

measure of wellbeing (Gatt et al., in submission)
 Gatt Resilience Scale (GR-S): sub-item scale defining
the ability to maintain flourishing wellbeing despite ↑
negative life events (Gatt et al., in preparation)
COMPAS-W
subscales

Example item

Composure

“When faced with a stressful situation, I make myself
think in a way that helps me stay calm”

Own-worth

“Knowing I have done something well is more important
to me than being praised by someone else”

Mastery

“I like to have a say in making decisions made by any
group I am in”

Positivity

“I laugh easily and am a cheerful high-spirited person”

Achievement

“I work hard to accomplish my goals”

Satisfaction

“How satisfied are you with your quality of life”
Funding: NHMRC CDF Fellowship 1062495 & ARC linkage grant 0883621
NHMRC CDF Fellow
 Dr Justine Gatt (BDC Sydney)
Investigators
 Leanne Williams (BDC Sydney & Stanford)
 Peter Schofield (NeuRA)
 Richard Clark (Flinders)
 Anthony Harris (BDC Sydney)
Industry Partners
 Brain Resource Ltd
 Freedomsway
Imaging Core
 Mayuresh Korgaonkar
 Stuart Grieve
PhD students
 Karen Burton
 Kaushik Ram
 Kylie Dowd
Thank you!

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Testing the impact of online brain training in promoting wellbeing and resilience, Dr Justine Gatt

  • 1. Testing the impact of online brain training in promoting wellbeing and resilience Dr Justine Gatt Senior Research Fellow Brain Dynamics Centre University of Sydney Medical School & WMI Westmead
  • 3. How to promote wellbeing and resilience?  In an effort to promote mental health, most research in psychiatry focuses on understanding mental illness, ways to predict it and treat it  However, mental health is not simply the absence of mental illness – only 25% commonality!  The questions remain:  What defines optimal mental health? What defines the flourishing and resilient individual?  Can these features be nurtured in people who may be low in resilience and wellbeing using intervention tools such as e-health platforms?
  • 5. The TWIN-E Study in Emotional Wellbeing Recruitment Australian Twin Registry: N approached = 9,622 //N double positive response = 2,370 (25%) • 1600 twins Phase I • 18-65 years, healthy • Tested across Australia Web Assessment + DNA saliva kit (N = 1,643) • Phase 1 & 2 tested for behavior and brain function MRI/fMRI/DTI EEG • Phase 3 involves a RCT N = 270 N = 451 trial to 30-days of Phase II: 12-months MyBrainSolutions cognitive training Completed in Mar 2012 Completed in Oct 2013 Web Assessment (90% retention) Phase III: e-health RCT To be completed in early 2014
  • 6. Aim 2: Evaluate efficacy in improving wellbeing & resilience using MyBrainSolutions© Games for positivity, stress reduction attention, memory Tools to track and reward yourself Assessment and Report on your own Brain Profile
  • 8. MyBrainSolutions improves psychological functioning over 30 days 2.4 Positive affect Depressed mood 3.0 2.2 Control 2.8 Mean Mean 2.0 1.8 1.6 1.4 2.6 2.4 1.2 2.2 1.0 2.0 Time 1 Time 2 Time 1 3.9 Emotion suppression 56.0 Social skills 55.5 3.7 55.0 Mean Mean Time 2 Pre-Post Treatment Pre-Post Treatment 3.5 3.3 54.5 54.0 53.5 3.1 53.0 2.9 52.5 52.0 2.7 Time 1 Time 2 Pre-Post Treatment Treatment Time 1 Time 2 Pre-Post Treatment
  • 9. Future studies: A new e-health tool developed by Freedomsway Meta-Analysis© for individuals Vantage Point© for organisations
  • 11. What I can offer / What I need  Collaborators interested in testing the e-health platforms, Brain Resource’s MyBrainSolutions or Freedomsway’s Meta-Analysis in their own cohorts  Collaborators interested in using our new scales of wellbeing and resilience for use in their own cohorts
  • 12. New measures of wellbeing & resilience  COMPAS-W Scale of Wellbeing: 26-item composite measure of wellbeing (Gatt et al., in submission)  Gatt Resilience Scale (GR-S): sub-item scale defining the ability to maintain flourishing wellbeing despite ↑ negative life events (Gatt et al., in preparation) COMPAS-W subscales Example item Composure “When faced with a stressful situation, I make myself think in a way that helps me stay calm” Own-worth “Knowing I have done something well is more important to me than being praised by someone else” Mastery “I like to have a say in making decisions made by any group I am in” Positivity “I laugh easily and am a cheerful high-spirited person” Achievement “I work hard to accomplish my goals” Satisfaction “How satisfied are you with your quality of life”
  • 13. Funding: NHMRC CDF Fellowship 1062495 & ARC linkage grant 0883621 NHMRC CDF Fellow  Dr Justine Gatt (BDC Sydney) Investigators  Leanne Williams (BDC Sydney & Stanford)  Peter Schofield (NeuRA)  Richard Clark (Flinders)  Anthony Harris (BDC Sydney) Industry Partners  Brain Resource Ltd  Freedomsway Imaging Core  Mayuresh Korgaonkar  Stuart Grieve PhD students  Karen Burton  Kaushik Ram  Kylie Dowd

Editor's Notes

  1. Initiated in 2009.