testicular tumor case presentation.pptx
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This document presents a case of a 25-year-old male who presented with a painless, gradually enlarging testicular swelling. Imaging showed cystic areas within the testis. The patient underwent a partial orchidectomy. Pathological examination revealed a testicular tumor consisting of multiple tissue types including cartilage, glandular epithelium, and skeletal muscle differentiation, consistent with a diagnosis of teratoma. Teratomas are germ cell tumors that contain mature tissues derived from all three germ layers. This tumor was classified as a postpubertal teratoma based on the presence of varying degrees of atypia among the tissue types.
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- 1. CASE PRESENTATION TESTICULAR TUMOR Presented By: Dr Lekhraaj Gautam PGT Department of Pathology Tezpur Medical College Hospital
- 2. Clinical History: A 25 year old male, presented to surgery OPD with a history of testicular swelling since last 6 months. It was painless ,gradually increasing in size and not associated with any trauma. No H/o undescended testis present. Following which, partial orchidectomy was done.
- 3. Radiological findings: USG cystic with heterogeneous echoes in the fluid
- 4. Biochemical findings: All parameters were within normal limit. Serum markers( β HCG and AFP) not done.
- 5. Grossing: Received a specimen labelled as left testicular tumor with spermatic cord. Measurement of Testis : 12×7×5 cm3 Spermatic cord : 10 cm in length External Surface : Lobulated and capsule intact. Cut Section : Multiple cystic areas noted containing serous fluid. Largest cyst measuring 3×2 cm2 Greyishwhite solid area noted(2.5× 1 cm2) Multiple random sections taken form solid and cystic areas.
- 7. On Scanner View: Variegated tissue seen in section comprising of cartilage, glandular epithelium, skin adnexal structures, multiple epithelial tissues, rhabdoid( skeletal muscle) differentiation. The cartilage is mature looking but other epithelial structures including rhabdoid are immature or primitive. No other germ cell component is seen after extensive sectioning.
- 13. Scanner view: Individual cells are large with well defined border, abundant eosinophilic cytoplasm with striation and prominent nucleoli.
- 14. Microscopy: Multiple sections examined. Section shows the features of teratoma of testis.
- 16. Postpubertal type •Demonstrate varying degrees of atypia •Any type of tissue may be present, such as gastrointestinal glands, respiratory epithelium, cartilage, squamous epithelium with keratinization, primitive undifferentiated spindle cells, or neuroepithelium •Will have GCNIS •Associated with atrophic testis with sclerosis and microliths.
- 17. Prepubertal type •More likely to have tissue arrangements mimicking organs (organoid morphology with tissue layers visible such as epithelium, lamina propria and muscularis propria) but any tissue type may be present. •Hair follicles may be seen (not in postpubertal type) •No cytologic atypia, GCNIS or necrosis; minimal mitoses
- 21. Teratoma ovary Teratoma testes Age: 20-30 yrs Mature and immature Hair, sebaceous material is commonly found Usually not mixed with other germ cell tumors Pre pubertal and post pubertal Although can be classified as mature and immature no prognostic significane Rarely found Uasually mixed with other other germ cell tumor( post peubertial)