Hewlett-Packard's exit from the middleware business has led to significant disadvantages, as major partners like Microsoft and Oracle have withdrawn support for its Itanium servers. This strategic error has left HP vulnerable, particularly now that control over its systems software is waning, especially if Itanium is replaced by Intel Xeon processors. In contrast, IBM demonstrates the competitive advantage of owning software stacks, showcasing substantial revenue growth through optimization of its systems software and virtualization solutions.