Summer Stationery Paper - Google Search Printable Li

Summer Stationery Paper - Google
Search Printable Li
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Summer Stationery Paper - Google Search Printable Li Summer Stationery Paper - Google Search Printable Li

Grieving Styles In Ordinary People
Society and culture have created scripts (i.e., social norms) that dictate the ways in which we are to
grieve. These scripts also prescribe the unique ways in which men and women are expected to respond
to grief. Specifically, men s grief scripts suggest that men will resolve to grieve in solitude as a
demonstration of their self reliance. Men may also have muted emotional response and expressed
emotions are typically in the form of anger or guilt (Martin Doka, 2011). Comparatively, women s
grief scripts suggest that women are more emotive and seek support from others to help cope with loss
(Martin Doka, 2011).
However, the characters in Ordinary People do not conform to the stereotypical gender grief scripts
and instead reflect the different grieving styles captured in Martin and Doka s (2011) grieving styles
continuum. Martin and Doka (2011) conceptualizes grieving styles ranging on a continuum from
intuitive to instrumental. Grieving styles reflect individuals ability to adapt to loss and are
distinguished by their use of cognitive and affective domains to process grief.
Based on Conrad s character in the movie, he could be described as having more of an intuitive
grieving style. This style of grieving utilizes more of the affective domain and uses little of the
cognitive (Martin Doka, 2011). For the intuitive griever, grief is characterized by the experience of
painful feelings. The feelings of guilt and sadness were those that Conrad experienced the most. After
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Ulcerative Colitis Connotations Of Tragedies
The word diagnosis had connotations of tragedy in my head, mostly because of movie depictions of
the diagnosis of cancer, which feature drama and despair. The meaning of diagnosis changed for me
on the fourth of January, 2012, when I heard the words Ulcerative Colitis for the first time. The words
flew over my head as I stared out the car window, eagerly awaiting my first solid food over twenty
four hours, and when I reflected on that moment for the first time, it didn t even qualify as a diagnosis
to me because of the anticlimactic mood. In my experience, the diagnosis mattered very little in
comparison to the disease, despite what I expected. At first, the worst aspect of Ulcerative Colitis was
the isolation I felt. Middle school was

Characterization Of The Novel Fearless
In the novel Fearless by Eric Blehm, the main character Adam Brown starts out in highschool being a
great student but, in college he finds some difficulties in his life. When everything does not go to
smooth, he tried drugs, and it just got worse as he used cocaine. He started stealing from his family
and friends and would run away, eventually his family had enough of him and was afraid of something
happening to him. His family and friends would always see the old Adam wishing he was still
there,but he no longer had control until he met his wife Kelly and tried his hardest. At Arkansas Tech
he was no longer the standout player on the football field, started getting mediocre grades, and in his
free time he would be at parties or the club. One night after a party with his old friends Jeff, Heath,
and Richard they were almost driven off the road and met four guys and got in a fight. One of the guys
had a blade in his hand and hit jeff right in the side, filled with anger Jeff quickly got back at him and
started pounding his head in but was soon pulled off by Adam. The guys then hopped back into the
truck until a one of them came back out with a shotgun and shot Jeff. Adam immediately ripped his
shirt off and walked to the guy with the gun and told him If you re going to shoot me, f ing shoot me!
(page 40 41) He then walked to the guy with the gun and said a few words, then took his friend to the
hospital where Jeff was barely breathing but was still alive thanks to Adam, he

Essay on Joint Strike Fighter (Jsf)
Joint Strike Fighter (JSF) Ron D. Knapp Professor Michael Meadows Park University Internet
Campus A course paper presented to the School of Arts and Sciences and Distance Learning in partial
fulfillment of the requirements for the degree of Baccalaureate LG201 Systems Engineering and
Analysis Park University October 09, 2011 The Joint Strike Fighter (JSF) program began with defense
reviews conducted by the Clinton Administration after taking office in 1992. At the time, several
government organizations were working on the next generation strike aircraft. Following an intense
competition, the U.S. Department of Defense on 26 October 2001, named Lockheed Martin lead ...
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The program collected data to manage manufacturing maturity, but currently unproven processes and
a lack of flight testing was of concern to the GAO because of a potentially costly future of changes to
design and manufacturing processes. Program costs continued to increase and the schedule had
slipped since the 2004 rebase line. Very little flight testing occurred as of the report s publication and
the first fully integrated aircraft was not expected to begin flight testing for at least 4 years. In 2007
the Department of Defense cut the number of test aircraft and flight test hours to maintain cost and
schedule plans. A fully integrated, capable aircraft was not expected to enter flight testing until 2012,
increasing risks that problems could be found and would require design and production changes, as
well as retrofit expenses for aircraft already built. On May 10, 2009, AA 1 had completed 84 test
flights, including a deployment to Eglin AFB. The first SDD STOVL aircraft, BF 1, had completed 14
flights. The second SDD aircraft, BF 2, had its first flight in February 2009. By December 2009, only
4 of 13 test aircraft had been delivered and total labor hours to build the aircraft had increased more
than 50 percent above earlier estimates. Late deliveries hampered the development flight test program
and affected work on production aircraft, even as plans

Friendship In The Outsiders, By S. E. Hinton
Have you ever truly realized how valuable friends are? S.E. Hintons The Outsiders is a book that can
make you realize just how important a friend can be. The main character, a 14 year old boy named
Ponyboy, lives with his brothers and is in a gang. Ponyboy sticks by his friends no matter what, and
runs away with one of them and lives in an old abandoned church for a couple weeks after his friend
does a horrible thing. One of the main themes in this book is most definitely friendship. Ponyboy
relies on his friend and his friends rely on him. Throughout the book, Ponyboy has a strong friendship
with his friend, who is also a Greaser, named Johnny. Johnny is such a good friend, he kills a person
from another gang called the Socs that was trying

Formal Research vs Business Proposal Essay
Formal Research vs. Business Proposals
Comparing and contrasting any business proposal can be a little confusing when there is little to no
knowledge of what either of the proposal really stands for or mean. Every business has the opportunity
for change or to seek change. These business environments are potential projects that intermingled
with the start of a new product. Depending on the company or organization s focus, will determine
which proposal is best to provide a basic and statistical approach to researching similar to the general
products that are on the market. Initiating these researches will give specific product either a saturated
appeal or if the product will ripen the business s ... Show more content on Helpwriting.net ...
While one is business is suggest new ideas and services which makes their business money or
business proposal; while the other business outlines the overview of finding what supports the
business, saves money, and satisfies the customers as well as keeps need customers and bringing in
more customers. Even though formal research implements the demand for a product business
proposals discusses a developing way to market a product where everyone will be satisfied by. Both of
these proposal documents provide the basic structural components that provide background and
introduction for identifying the business s research. The main similarity is the focus and feasibility
that addresses the specific and detailed concerns that will determine whether the suggestions will be
successful or unsuccessful. Formal research and business proposals go hand in hand in the business
world. Business proposals seek a developmental goal that seeks to find new clients and projects while
responding to the formal requests proposals. To sum it up business s proposals suggest strategies while
formal research establishes facts in order to draft a proposal. Collection of information from managers
on how to engage better with employees based on commitment and communication will show the
employee appreciation. Employees who feel they are appreciated will have better

Tragic Events During The Holocaust
During the time of the Holocaust, The Jews were persectuted and brutally killed by Adolf Hitler;
because of their beliefs. This event has shaken Jewish religion and still had some after effects. Jews
say that the Holocaust is the most shattering event in history. Because, some of those Jews still alive
today still remember the killing hurt that were brought upon to their people. The Jews view this time
as the most painful time in their history.
There is no explanation to these tragic events; there are some theories. Like for example; maybe Hitler
was crazy and he hated the Jews. So he orderd them all to be killed. Some, say that they were Christ
killers and deserved to die. Raoul Hilberg wrote a book called; The Destruction of the European

Father Of The Bride
Father of the Bride Write up Father of the Bride is a movie about a young girl who decides to get
married to a man her family has never met before, and it follows the ups and downs of a family trying
to figure out how to deal with the new changes to their family. The biggest struggle in the movie is the
father trying to cope with letting go of his little girl; letting her grow up and become primarily cared
for by someone else. The movie also covers other struggles, such as meeting the in laws, cost and
immensity of weddings, and relationship struggles between the bride and groom leading up to the
wedding. In the end, George, the father of the bride, is able to let go of his daughter Katharine and
give her the independence and confidence in her that she needs to let herself be happy with Bryan and
her new life. I think the movie is a great representation of what a ... Show more content on
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For example, George has problems with coming to terms with the fact that Katharine s love for Bryan
is true love and not infatuation or lust, but eventually trusts her judgment to know it is real. In class,
we also talked a lot about the myths of marriage and process of getting married, and those myths were
verified in the movie. For example, the idea that planning a wedding is a super happy, romantic
experience is not true. In the movie, the planning is chaotic and stressful and there is a point when
Katharine and Bryan get in a fight and she wants to call of the wedding, which I think is something
that happens a lot more than one might think, but because people tend to not like to show that side to
wedding planning, those experiences are usually omitted. Another connection between the movie and
class, in particular the wedding budget project we did in class, is how many tiny little details that need
to be covered with wedding planning and how the cost of every tiny thing really adds

Robert Frost s Design As Seen Through The Lens Of His...
James Giltenan
LTCM
Erik Gray
TA: Michael West
26 October 2016
Robert Frost s Design as Seen Through the Lens of His Earlier Poem Range Finding In Robert Frost s
Design, written in 1922, the narrator laments the juxtaposition of life and death that he bears witness
to when he sees a spider on a heal all flower carrying the dead moth it has killed. He uses a modified
Italian or Petrarchan sonnet, punctuation, repetition of rhyme and diction, repetition of anomaly, and
repetition of the same rhyme in both the octave and the sestet, to convey that death is a question that
cannot be answered and that the only solution, the only answer, is to continue to ponder over it. While
it is a question that cannot be answered, it must be questioned anyway. He uses symbols he has drawn
from in earlier works, as well as his experience playing with the form of the Petrarchan sonnet in the
past, to help shed light on the importance of this. Using a modified Petrarchan sonnet, Frost is able to
use the formal rhyme scheme in the first eight lines, called the octave, of abb/aab/ba. While the rhyme
scheme of the second six lines of the poem, called the sestet, follows less stringent guidelines, Frost
uses that of ac/aa/cc, which is extraordinary in that it carries over the a of the octave s rhyme scheme
and introduces it into the rhyme scheme of the sestet. Usually the sestet introduces new rhymes of c
and d but Frost chooses to only introduce one new rhyme to its scheme, that of

Fire Rooster Research Paper
A good way to ring in the Year of the Rooster is to play two amazing Chinese New Year slots. One is
Chunjie from Endorphina and the other is Fire Rooster from Habanero. Both games have amazing
Chinese themes and bonus features.
Bitcoin owners will get the chance to take these two slots for a spin. Fire Rooster is available in
BetChain since the casino offers other Habanero slots. Bitcoin casinos like PrincessWin might also
have Chunjie slot available in the near future.
Chunjie (Endorphina, 5 reel, 38 payline)
Chunjie is the translated name of Chinese New Year which is also Spring Festival . It is a time for the
Chinese to hold a number of traditions. This includes giving red packets or envelopes to children.
Another is to light up some fireworks. The majority of these traditions are done in order to drive ...
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The tale is about how the rooster loses its crown to the dragon because of the Centipede. The Rooster
Lament fits the upcoming Chinese New Year since the tale took place at a time when the Jade
Emperor was choosing which animal to represent a year.
Habanero s Fire Rooster has a number of symbols that references the tales. This includes the rooster,
dragon, and centipede. The slot also has a good mixture of gold and red colors which are common in
many Chinese New Year decorations.
Fire Rooster s bonus feature is the Rooster scatter mode. During this mode, players receive a number
of free spins. If bettors can get the Rooster to appear in any of the reels, it will randomly convert any
symbols adjacent to it into a wild symbol. There is a potential for a large payout if there are more than
three roosters during the bonus feature.
The Fire Rooster also has a progressive jackpot feature. The prize amount of the jackpot increases as
more and more people play the game. Winning the progressive jackpot can occur at random and
during any mode of the

Resilience Of Resilience Across A Lifespan
Resilience across a lifespan can happen many different ways from physical development to cognitive
development. We also have social and emotional development. Throughout this paper resilience will
be applied to all of the above mentioned concepts. Resilience across a lifespan is described through
theories, measures, and even personality characteristics. Resilience has also been applied to the
impacts of disasters and traumatic experiences in which will also be touched on throughout this paper.
Resilience is discussed as to whether it is an inherited trait or whether it is a learned trait. Resilience
can be found in everyone. Some people have more resilience due to life experiences which you will
see explained throughout this paper as well.
Resilience is described as the process of adapting well in the face of adversity, trauma, tragedy,
threats, or significant sources of stress (American Psychological Association, 2016). Resilience is an
ordinary thing in human beings. It is often described as bouncing back, which refers to bouncing back
from difficult times or stressful situations. As a person grows older resilience grows as well. A person
s past can most certainly affect how a person uses resiliency in the present. If a person is not affected
negatively a lot in their past when it comes time for a person to bounce back, they will not bounce
back as smoothly as a person who has had a very traumatic past and has learned how to bounce back
in a smoother fashion.

Programming Bacteria To Sense Pressure Case Study
Programming bacteria to sense pressure
Neydis Moreno and Megan N. McClean
Pattern generating circuits coupled to production of organic material with inorganic interfaces allow
bacterial colonies to generate composite structures with unique function.
Mother Nature generates sophisticated and complicated structures from the humblest of ingredients.
Often their construction relies on the self assembly of building blocks resulting in hybrid structures
that combine both organic and inorganic materials. For example, Shewanella bacteria are capable of
forming extracellular networks of arsenic sulfide nanotubes with unique electrical and
photoconductive properties1. Our ability to mimic these natural processes to create desirable nano and
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Cao, et al2 take advantage of an existing circuit capable of generating spatial patterning in two
dimensional populations of bacteria6 to pattern production of a modified curli protein in colonies of E.
coli. Curli is an extracellular amyloid material produced by E. coli that forms fibrils based on self
assembly of the major secreted curli subunit (CsgA) and an additional subunit CsgB. The authors
utilize the circuit described in Payne, et al (which consists of a positive feedback loop (mutant T7
RNA polymerase T7RNAP activates its own expression) and a negative feedback loop based on
production of a diffusible quorum sensing molecule AHL (see Figure 1). . Expression of the curli
protein occurs at high levels of the quorum sensing molecule AHL. By engineering curli to contain a
polyhistidine tag (6XHis) it can be interfaced with inorganic materials, for example, gold
nanoparticles conjugated to Ni Nitrilotriacetic acid (NTA).
Cao et al use ink jet printing to print cells onto membranes to form single colonies of E. coli
containing this synthetic curli producing circuit. They found that the spatial patterning circuit caused
curli to be expressed in the exterior of the colony, forming domed curli structures. In contrast, cells
constitutively expressing curli without the patterning

DLA-Energy
Lastly, while it does not reduce fuel usage, modifying the method in which the Air Force purchases
fuel will certainly have a positive effect on the total cost of energy. The Defense Logistics Agency
Energy (DLA Energy) is the primary supplier of bulk petroleum, oils, and lubricants (POL), including
all variations of jet fuel. Currently, DLA Energy offers a level of price stability through the use of a
standard price of fuel. The standard price is set nearly a year in advance of budget execution to
approximate the actual price per barrel during execution, and is calculated using fuel price projections
for the next 18 months . This projection includes the costs of transporting, storing, and managing the
government fuel system which includes ... Show more content on Helpwriting.net ...
Figure 13 shows the historical variance between DoD estimated fuel costs vs actual. Figure 13: DoD
Estimates Versus Actual Fuel Costs (2009 2013) The USAF could reduce their fuel cost simply by
implementing a different method for fuel procurement with a secondary benefit of stabilizing the
volatility in fuel prices. By mitigating exposure to volatile jet fuel prices, the Air Force will stabilize
fuel budget and achieve an average price of jet fuel either at or below DLA Energy s standard price of
fuel. One possible fuel procurement strategy is for the Air Force to develop an official fuel hedging
policy. Fuel Hedging can assist with stabilizing fuel budgets, as it allows for the establishment of a
fixed or capped fuel cost, which helps to mitigate exposure to volatile and increasing fuel prices. Over
96 percent of airlines maintain official fuel hedging policies with the primary purpose

International Trade And Economic Growth
Nowadays, the international trade is very important for a growth economy, specially with advanced
technologies that facilitate communication. To obtain financial and technological resources for
economic growth, the nation needs certainly to participate in world trade. International trade of
developing countries leads to high growth and significant changes in the commodity structure by
reflecting changes in the economy. The countries in all over the world are economically
interdependent. No any nation can exist in economic isolation. If the economy of one nation crashed,
other nations in the world will probably be unstable as well. And that would be worse if that nation
among to developed nations. The gains from trade are dynamic because they cause changes in
economy s evolution through time. From a macroeconomic perspective, we can analyze the gains
from trade by focusing on the relation between trade openness and economic growth. From a
microeconomic perspective we can analyze the gains from trade by focusing on connections between
firm productivity and access to international markets. Recently, the literature on the dynamic gains
from trade takes a different approach rather than broad based measures of GDP and economic
openness. On the theory side, the heterogeneous firms models of Melitz (2003) and Chaney (2008)
present a rigorous basis for the existence of a link between trade liberalization and within sector
productivity gains: as less productive firms exit the market

How Did The New Deal Help America
he new deal of the 1930s was seen as the radical action needed during the depression to help American
people and the American economy. However, some people criticised it for not being radical enough as
it didn t help all Americans. Roosevelt started off by introducing 15 acts in his first 100 days including
the alphabet agencies and the beer act. These acts and agencies were designed to help certain groups
of people but this meant that some were left out. This meant that Roosevelt was forced into producing
the second new deal which helped Americans in the late 1930s.
The first couple of acts were very important, first there was the emergency banking act which closed
all banks for several days in which time they were inspected and only those ... Show more content on
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They built 33 dams to control flooding of the river and produce electricity. There were also measures
taken to improve the quality of the soil so that it could be used for farming again and a 650 mile
waterway to link the river systems. Thousands of jobs were created with the building if the dams and
the TVA became the biggest producer of electricity in America meaning many industries moved into
that area creating jobs for the unemployed. The dams still provide some of America with electricity
today which shows they were a

Literary Devices Used in Albert Camus The Plague
A book of horrors, fear and death. The Plague is a book by Albert Camus which weaves these
emotions and events into one suspenseful tale. Each paragraph and section is written and structured in
such a way as to give the reader insight into the feelings of the victims of the plague, and to show
somewhat of a theme. The passage from section 4, part 4, line number 1 to line number 35 gives us a
glimpse of the melancholy of the people of Oran to their dead loved ones to the extent that they do not
attend All Souls Day, for they were thinking of them too much as it was. Albert Camus fills this
passage with figurative devices, including, diction, personification, pathetic fallacy, metaphors, irony
and a turning point. The first two paragraphs ... Show more content on Helpwriting.net ...
Diction is seen to be used greatly in conveying the suitability of the town for All Souls Day. Pathetic
Fallacy is also used to portray the message by Albert Camus. Also, the cool wind , big clouds...trailing
shadows , glossy and oiled clothing give the impression of a cool, damp shadowy day, with clothing
mimicking this, portraying the psychology of the people of Oran when they are in melancholy for their
loved ones. However, from around the third paragraph onwards, a turning point is seen. As previously
suggested, it was a suitable time of the year for mourning and All Souls Day, but ironically this did not
occur. Albert Camus devices and literary intelligence make it very clear that the melancholy of the
town was to the extent that All Souls Day was neglected. It is seen by a turning point, But these
familiar aspects of All Souls Day could not make us forget that the cemeteries were left unvisited .
This turning point suggests that All Souls Day did not occur as it was previously suggested through
earlier devices, mainly due to the already prevalent grief towards the dead. Albert Camus metaphors
clearly clarifies this, they (the dead) were no longer the forsaken to whom...you came to justify
yourself and they (the dead) were intruders whom you would rather forget .Also, these metaphors give
insight to the attitude of the townspeople towards their dead, that the extended period of thinking and
grief over their dead has caused them not

Phases Of Interrogation At The Most Comfortable
Phases of interrogation The first phase of the interrogation is to establish the norm. This is done to
determine the general behavior of the subject, as the goal is to establish the characteristics of the
subject at the most comfortable. As a result, the interviewer can then interpret the subject s behavior
and communication as the interrogation goes on. The second phase is to build credibility. The
interviewer describes his or her job and experiences, giving examples of situations that are commonly
encountered, and judges the subject s reactions along the way. The interviewer s goal in building
credibility is to convince the subject that he or she is caught of committing a crime without stating any
accusations or revealing evidence. The third phase is to create an opportunity for the subject to save
face and transfer blame. The interviewer guides the subject into telling the truth. The goal is to make
the subject feel better about admitting the truth by finding a socially acceptable reason for being
honest. The subject will feel better about telling the truth if he or she feels that admitting what
happened is better than being caught lying, and if the reason for the crime was for non malicious
reasons. The fourth phase is to establish a sense of urgency. In this phase, the interviewer explains to
the subject that he or she has a limited amount of time to tell the company his or her side of the story.
The interviewer explains that the company may make a decision

The Controversial Book Mein Kampf By Adolf Hitler
Mein Kampf is a very controversial book that is an autobiographical written by Adolf Hitler and how
he describes his thoughts, ideologies, feelings, frustrations, anger, and his future of the world. Mein
Kampf is a book that is probably one of the most controversial books around the world. The main
topics in the book include anti communism, antisemitism, aryanism, Nazism, genocide, military,
political ideology, and Adolf Hitler s feelings and frustrations. These main topics also tie into the plot
of the book. All of these topics can cause some sort of controversy that makes this book always near
the challenge or ban book list. Many countries allow the book to be read but some others do not. It all
depends what country it is and the kind of ... Show more content on Helpwriting.net ...
In countries in today s world, China, North Korea and Germany are the only countries that have the
book on a ban list. North Korea and China only ban the book due to their countries being communist
and totalitarian making them control what they want their citizens to read. Germany bans the book
really and truthfully because they want to hide the past and try to remove that from part of their
history. Although Germany just recently is about to lift the ban on the book in 2015, it has been ban
for awhile due to them trying to erase the past. In countries like the United Kingdom and the United
States, the book is able to be sold and read freely. Even though it is able to be read freely in the United
States some groups of people challenge the book. For example, many school systems ban the book
from their curriculum due to its offensive content and language. Although many schools have it in
their libraries for students able to do an independent reading on the book. Some groups of people that
do challenge the book due to its offensive and harsh content are the Jewish people, some liberal
groups, and peace

Media Censorship Affects The News You See
The Article How Media Censorship Affects The News You See talks about how the government
blocks the information from reaching you. It talks about the act of censorship and how it can be seen
when a person s private information is concealed, graphic details and images are kept hidden, hiding
political bias viewpoints, etc. This is a start to a dystopian society, as news programs have the control
and power to change real information with false facts, leading the public to believe lies. This can be
seen in a more extreme manner in the novel Fahrenheit 451 by Ray Bradbury on page 32, when
Montag is given a rule book containing a brief history of the Firemen in America. He reads,
Established, 1790, to burn English influenced book in the Colonies.

Complications Of Formulas And Soldations In A Business
Dear Mr. Bill, I am very happy that your business is doing well, I would be more than happy to assist
you with your questions and concerns, below is a written report of my suggestions and
recommendations in having your business runs smoothly and successful. 1) You have created a
spreadsheet to help keep track of your expenses and I have noticed that you have not totaled your
expenses. In spreadsheets there are ways that you can total by using formulas or functions. For
example at the top of the spreadsheet from A H these are called columns so in the F column type in
=SUM (B5:E5) then you hit the enter key on the keyboard. To get through each day in each row in
column F you repeat the steps but this time you changed only the number for ... Show more content on
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With the Peer to Peer Network it is decentralized and can connect up to ten computers at once, each
computer is plugged into a hub or a switch. Each worker who is an administrator, each has a local
account, each computer has a name to it, and each user can control access from their computer to
another user s computer, each user can access or share files in other for that to happen the user need to
know the name of computer they wish to connect to and access to printing or scanning may be
cumbersome as usernames and passwords being remembered is vital in order to gain access. It needs
absolutely no training and it is not costly, however as mentioned earlier remembering the usernames
and passwords are vital. I would recommend that you choose Peer to peer because it is costless and
easy to use, besides having to remember all the computer names and passwords. The second Network
is the Client/Server Network, the Client/Server Network is a centralized network, reasons for, all
computers will be connected to a server which is in the centre there will be one central administrator,
you could assign a staff or you could be the own administrator, only the administrator decides what to
share and not share, this means files will be a lot safer and some files will remain secure. It also
connects up to ten computers or more. This network is quite expensive and you will need to be trained
to use it. This network would

Potential Therapeutics For Treating Type 2 Diabetes Mellitus
Bromophenols have been identified as potential therapeutics for treating type 2 diabetes mellitus
(T2DM) due to their suspected tyrosine phosphatase 1B (PTP1B) inhibitory activity. A new series of
bromophenol analogues will be synthesised and their PTP1B inhibitory activity will be tested in in
vitro enzymatic assays to elucidate their mechanism of action as PTP1B inhibitors.
Background and Introduction
Type 2 diabetes mellitus (T2DM) is a metabolic disease that is caused by insulin resistance of the
peripheral tissues and impaired insulin secretion of the pancreatic β cells.1 Both conditions result in
reduced glycemic control, which can lead to hyperglycemia. Despite the availability of a wide range
of anti diabetic drugs to treat T2DM, ... Show more content on Helpwriting.net ...
Bromophenols have attracted much attention as potential PTP1B inhibitors due to their suspected anti
diabetic activity.4 Bromophenols occur naturally in marine organisms such as algae, mollusks and
jellyfish. (±) Polysiphenol (1, figure 1) is an example of a bromophenol that can be extracted from the
marine algae Polisiphonia Ferulecea.5 After the Braddock group successfully achieved the first total
synthesis of (±) polysiphenol and the separation of its enantiomers, they collaborated with the
Woscholski group to test their inhibitory activity in PTP1B enzymatic assays.6,7 Both enantiomers of
polysiphenol were essentially found to be identical in PTP1B inhibitory activity. Thus polysiphenol, as
single enantiomers, cannot be responsible for the observed inhibition. This implicates a chemical
change of polysiphenol into a non chiral form is likely to take place under the conditions of the assay.
One possibility is the formation of a para quinone methide species (4, figure 1), which in turn can
tautomerise into an ortho quinone methide species (5, figure 1). Thus there are various possible
reactive species that might be responsible for the observed inhibition of PTP1B. The formation of
quinones highlights a red flag in drug discovery due to their highly reactive nature. Quinones are
Michael acceptors that are known to cause toxicity in vivo by covalently binding to nucleophilic sites
on proteins and DNA.8 Consequently, quinones

Blackberry Picking
Weaving Maturity and Innocence Together; an Analysis of Blackberry Picking As people grow into
adulthood, they experience a loss of innocence, a series of events that leads them to see the world in a
different, darker lens. Seamus Heaney s 1999 poem Blackberry Picking explores this idea. This poem
uses mature diction combined with a childish rhyme scheme of AABB to explain how the sweetness
of one s youth becomes soured when they experience reality and how this process is inevitable in
tainting their past. As the reader analyzes this poem they immediately recognize the seemingly out of
place mature language used in a poem about berry picking. The text uses words such as thickened
wine and lust for. These are very adult phrases and topics used to describe a childhood memory, which
helps show that when one loses their innocence, their recollections are permanently changed. Another
way the mature diction is used is a contrast to the childlike story that is being told in the poem. This
extreme contrast is important because it ... Show more content on Helpwriting.net ...
The poem uses the simplistic rhyme scheme of AABB, which is typically found in nursery rhymes and
children stories. By using this rhyme scheme for the whole poem, the speaker is able to make known
that the poem is about a memory of blackberry picking, not a current event. The lines also end very
simply, ending with rhymes such as clot/knot and sun/ripen. Yet, as the poem continues the rhyme
schemes become muddled and lost, which is shown through rhymes like pots/boots and sour/fair. The
rhymes don t fit with the beginning of the poem, similarly how the mature language doesn t fit into the
poem. The poem ultimately ends with disappointment, with the line Each year I hoped they d keep,
knew that they would not. This helps tie the overall theme that nothing truly stays the same, that
everything ends, including

A Successful Obama Inaugural Address
Shamik Patel Professor Valarie Writing Project #3 November 5, 2014 A Successful Obama s 2nd
Inaugural Address On January 21st, 2013, Barack Obama addressed the audience as the re elected
President of America in an inaugural ceremony on the West Front of Capitol. The speech was written
by Jonathan Favreau. In an inaugural address, Obama touched upon several important issues;
immigration, gender equality, and economic reforms and left behind the message that unity is our
nation s ultimate strength. He was able convinced the audience that they should all work together to
overcome all issues and for a better tomorrow for the next generation. Obama successfully persuaded
the audience by exemplifying that he was aware of their issues, problems, and future needs. Greek
philosopher Aristotle divided the means of persuasion, appeals, intro three categories; ethos
(credibility), pathos (emotionally), and logos (logically). Obama persuaded the audience with use of
rhetoric and convinced them his arguments were credible, logical, and appealed to them emotionally.
In late 1950s, Richard Neustadt wrote Presidential Power and the Modern President, in which he
explained that presidential power is the power to persuade. Central motivation of this book was to
advice new president with their strategic problem of power and so forth. According to Neustadt, there
are three significant areas that a president must be aware of and nurture while in the Whitehouse;
power to persuade, president s

How Did Pol Pot Corrupt
Pol pot was the leader of the Khmer Rouge regime. In his early years, he was born eighth of nine
children on May 19th, 1925. He had a decent childhood and a good education, but we still ask
ourselves questions like, what was it that lead him to kill over 2 million citizens of Cambodia between
1975 and 1979? What made him corrupt? How different is he really from Julius Caesar?
Pol Pot was the leader of the Khmer Rouge regime from 1975 to 1979. From the moment he was in
control of Cambodia he set the calendars to year zero. His goal was to recreate Cambodia as a natural
society, eliminating any trace of the modern world. Modern materials were seen as impure and
dangerous and were quickly disposed of. Any intellectuals, artists, or monks were

Essay Comparing Dulce Et Decorum Est And Futility
Wilfred Owen combines realism with a romantic lyric poignancy and a visionary mode that enables
him to lead us to a true understanding of the personal costs of war. His veracity and close proximity to
World War one confronts us as well as shows compassion for the young men that fought. Both his
poems Dulce et Decorum est and Futility explore the psychological, physical and the futile costs that
war brought upon us. Owen s poetic skills, vivid language and sensory imagery express his bitter
animosity of those who encourage war in Dulce et Decorum and the pointlessness of war and perhaps
life itself in the poem Futility.
Psychological
Owen writes with an eloquent style and his use of poetic techniques accentuate the brutal destruction
... Show more content on Helpwriting.net ...
Futility starts with Move him into the sun . The verb move is an inexact word however, we feel the
movement has to be gentle in contrast to Dulce et Decorum est where the body was flung into the
Wagon. Straight away we are able to see the contrast of how Owen presents physical death in both
poems. Both poems abundantly use imagery in slightly differently ways; Dulce et Decorum est the
imagery is vividly graphic and grotesque done deliberately to make us feel uncomfortable. The first
stanza begins with soldiers trudging through the ubiquitous sludge and the dual adjective knock kneed
shows physical exhaustion and fatigue of the young men that instantly reverses this idea of them being
noble and healthy fighting. Followed by the visceral imagery the blood come gargling from the froth
corrupted lungs . This effectively recreates the scene Owen witnessed to involve the audience by
encouraging them to hear at every jolt the physical horror the soldiers suffered and invoke their pity.
Owen uses imagery more subtle in Futility. He creates this repetitive image of the sun as having
revitalising ability to bring back the dead and present the realness of physical death on

How Does Shaun Tan Use Visual Techniques In The Rabbits
The rabbits, an illustrative book by John Marsden and Shaun Tan, is a visually intriguing piece that
evokes empathy toward the Indigenous Australians; using a wide variety of visual literary techniques
to create a captivating, historical story. The story follows a historical look at the European colonisation
of Australia and it s devastating aftermath on the indigenous people and the land itself. Shaun Tan has
really brought the book to life with his use of visually interesting aspects such as anthropomorphic
characters, brilliant use of colour and the overall layout of the images. An excellent example of the
visual literary techniques in this book would be the They came by boat, page, which is also featured as
the front cover of the book. ... Show more content on Helpwriting.net ...
The page has quite a bright, mystical styled colouring that may emphasise the fact that the rabbits are
new to the land and the numbats have never seen anything like them before. The bright off white
ground is quite a good example of a good use of colour as it symbolises the purity of the land and how
the indigenous people worked with it. The dark, almost black, shadows of the rabbits would symbolise
their take over of the land and how it is being changed and harmed by the rabbit s arrival. There is also
the difference in the sky colouring behind the boat and in front of it; that may signify the rabbit s
darker past, and the lighter more cheerful presents of the numbat s

Tsa Policies Essay
As an aviation management major airport security is a concern that I have taken a huge interest in.
Making travel safer to air travelers is one of the biggest tasks that will never end as long as there is a
plane in the sky. However, there are many problems that come about when traveling because
passengers feel as if they are being harassed, which doesn t set a good look for the Transportation
Security Administration. The Transportation Security Administration (TSA) consist of 50,000 security
officers, inspectors, directors, air marshals and managers who protect the nation s transportation
systems so you and your family can travel safely. They look for bombs at checkpoints in airports, they
inspect rail cars, they patrol subways with our ... Show more content on Helpwriting.net ...
Finally, the DHS found that the TSA had implemented procedures to investigate and resolve passenger
complaints regarding the screening process.
The TSA maintains a screening Performance Management Information System (PMIS) where
recorded complaints are logged. Operations research analysis teams and federal security directors
review complaints logged in the database to track trends and identify areas of concern and take
appropriate actions, including possible disciplinary actions, to resolve specific issues. Complaints
involving allegations of discrimination based on color, race, gender, religion, or national or ethnic
origin are forwarded to the TSA s Office of Civil Rights for further investigation. Despite considerable
concern raised by some regarding inappropriate behavior during pat down screening procedures, the
DHS found no problems with the technique.
Nonetheless, privacy groups, such as the American Civil Liberties Union (ALCU), continue to express
concern over potential intrusion on individual rights and alleged cases of sexual harassment and abuse
of passengers, particularly female passengers, by TSA screeners. These concerns, however, raise a
significant challenge for the TSA: to maintain high levels of security, which require resolving all
alarms and screening in detail those passengers ascertained to pose an elevated security risk, while
maintaining the privacy rights and dignity of passengers identified for these secondary

How Does Adam Lose His Innocence
Adam has lost his mind and his innocence after he went through the terrifying experience that is his
life. In the beginning of the book, Adam was undeniably naïve and innocent then after everything he
went through he lost his innocence. As you read the book it is clear that even as a young child Adam
was naïve and thought that everything was congenial before he learned the truth. Cormier shows how
the protagonist Adam is a dynamic character that loses his childlike innocence because his parents
death and learning the truth regarding his life and his identity. Adam was naïve and innocent at the
beginning of the novel however that shifts as you read on. He was innocent because as a young boy he
didn t have a care in the world and he always sang the same song The Farmer in The Dell . Adam didn
t notice that his family was in grave danger until he heard his parents conversation and knew ... Show
more content on Helpwriting.net ...
Once Adam learned that he isn t who he thought he was and that his family was running away he didn
t know who he was. It made him lose his innocence because it showed him a different world and it
changed everything. He needed to take precautions of where he went and who he talked to and that
made him grow up. He needed to change his ways and live a different life and that once again
transformed him. Learning that he wasn t Adam Farmer changed him so much because he didn t know
who he was. Everything that he knew or thought he knew change and he was so surprised he didn t
know who he was anymore. Once Adam didn t know who he was anymore it made him think
differently and that definitely took away his childlike innocence. He was, without a doubt, naïve
because he didn t understand many things but after he learned the truth he learned what to do and what
not to do. That is how Adam lost his childlike innocence because of learning the truth regarding his
life and his

Developments in the Field of Nurse Anesthetists Essay
Nurse Anesthetist and their journey to where they are now Nurses have played an important role in
medicine throughout the years. When people hear the word nurse they often think of the ones in the
hospital given care and educating. Many people don t think about the other branches of nursing like
the nurse Anesthetist. A nurse Anesthetist has contributed a great deal in administering anesthetics for
about 150 years. Nurse anesthetist have struggled with autonomy and being able to practice without
being supervised by an Anesthesiologist. They also were limited to work in specific areas but now
they work in many hospital and outpatient settings. Nurse anesthetists have come a long way and are
conducting research and are helping improve ... Show more content on Helpwriting.net ...
According to 1999 report from the institute of medicine anesthesia care in nearly 50 times safer than
in the 1980 s (Riley 2012). This show how the field of nurse anesthetist had improved and grown over
years. Nurse anesthetist work in many setting from the hospitals, dental offices to out patient settings.
They also provide care to rural hospitals that if it wasn t for CRNAs they wouldn t have a specialist in
anesthesia and would have to travel along way to receive this service. Nagelhout Plaus (2013) talk
about the progress that has occurred in all areas of the anesthesia discipline. The AANA Foundation
lists and describes hundreds of recent and ongoing CRNA led research projects. These projects range
from basic and applied sciences to clinical anesthesia, education and economics. They also include a
Chuck Biddle, CRNA Phd the editor in chief of the AANA journal and who wrote Of great pride to me
is the quality and diversity of work that I see emerging from colleagues nationwide, research that is
altering the landscape of anesthesia care.....The age of evidence based practice is upon us and we
should actively embrace the opportunity.. (Nagelhoult Plaus 2013). This encompasses what CRNAs
have accomplished throughout the years and demonstrates how far they have come. From being just
nurses trained to administer anesthesia in the 1800 s s to conducting research. It s a great joy to see
CRNAs

Compare And Contrast Referential And Descriptive Statistics
Descriptive and Inferential Statistics Paper
Descriptive and Inferential Statistics Paper
Statistics are used for descriptive purposes, and can be helpful in understanding a large amount of
information, such as crime rates. Using statistics to record and analyze information, helps to solve
problems, back up the solution to the problems, and eliminate some of the guess work. In Psychology
there has to be a variable or variables to be organized, measured, and expressed as quantities.
Information is usually in the form of a frequency table, histogram, or bar graph to show the increase or
decline in occurrences over a period of time. Psychological statistics is used to keep track of
behavioral reactions to certain stimuli, and since ... Show more content on Helpwriting.net ...
Simply put, it refers to both the process and the result. This illustrates the functions of statistics as
gathering, organizing, and analyzing data and also as drawing conclusions and forming hypotheses.
Descriptive and Inferential
One could describe descriptive statistics as collecting, organizing, summarizing and then presenting
data. Inferential statistics may be explained as making predictions, making inferences, determining
relationships, and hypothesis testing. To express the fundamental characteristics of the facts in a
certain examination one would use descriptive statistics. This type of statistics presents
straightforward outlines about the example and the quantity. Thus with detailed illustrative
examinations, they shape the base of nearly all quantitative analysis of data. To summarize a
collection of data in a clear and understandable way is the most essential use of descriptive statistics
(RVLS, 2009). Numerical and graphical are the two crucial methods in descriptive statistics. If one is
using the numerical style one may calculate statistics by using mean and average differences.
Descriptive statistics are usually recognized from inferential statistics. With descriptive statistics it is
simply describing what is or what the data shows (Social Research Methods, 2006). With inferential
statistics, it is trying to reach

Gay Rights Against Civil Rights
There is a constitutional right to life, liberty, and the pursuit of happiness. It would be unconstitutional
to criminalize same sex marriage, or any marriage, regardless of gender, or sexual orientation.
Criminalizing same sex marriage is unacceptable due to it being discriminatory. It violates the civil
rights of homosexual people by not allowing them to pursue their happiness. The Constitution clearly
states this: No state shall make or enforce any law which shall abridge the privileges or immunities of
citizens of the United States; nor shall any state deprive any person of life, liberty, or property, without
due process of law; nor deny to any person within its jurisdiction the equal protection of the laws.
(14th Amendment) To deny same sex couples their right to receive a marriage license, and the refusal
to recognize these marriages, violates the equal protection clause of the Fourteenth Amendment in the
United States Constitution. The only instance in which the constitution has been amended, was in
1920, when alcohol was federally prohibited ( Gay Marriage ). President Bush wanted to call for a
constitutional amendment to ban gay marriages, however, that would be a violation of the peoples
rights. That is due to the fact that the Constitution of the United States of America is for the people,
regardless of sexual orientation. President Bush s call for an amendment sparked controversy amongst
the Lesbian, Gay, Bisexual, Transgender community, triggering the early

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