This document defines various terms related to suicide and discusses suicide from epidemiological, etiological, and clinical perspectives. It notes that over 90% of suicides are associated with psychiatric disorders like depression and substance abuse. Key risk factors include male gender, older age, social isolation, impulsivity, and a family history of suicide. A comprehensive suicide assessment evaluates psychiatric illnesses, risk and protective factors, and determines the level of risk to guide treatment and safety planning.
suicide - a public health problem
history, global scenario, Indian scenario, etiology, risk factors. protective factors, suicide in adolescents, treatment, prevention, recommendations
Suicide, it’s importance, global burden, burden of suicide in India, theories of suicide, it’s prevention, psychiatric co-morbidities associated with suicide, its treatment
What is suicide? It is discuss in this presentation.
This slide covers theory and types of suicide, what are the reasons of suicide? What are the impacts of suicide?
Suicide prevention and role of media in preventing suicide also discuss in this presetnation.
suicide - a public health problem
history, global scenario, Indian scenario, etiology, risk factors. protective factors, suicide in adolescents, treatment, prevention, recommendations
Suicide, it’s importance, global burden, burden of suicide in India, theories of suicide, it’s prevention, psychiatric co-morbidities associated with suicide, its treatment
What is suicide? It is discuss in this presentation.
This slide covers theory and types of suicide, what are the reasons of suicide? What are the impacts of suicide?
Suicide prevention and role of media in preventing suicide also discuss in this presetnation.
Suicide, risk factors, assessment and methodological problemsDr. Amit Chougule
Seminar on Suicide from a psychiatric point of view
definition, global and indian epidemiology of suicide, risk assessment of suicide and methodological issues associated with risk assessment and suicide research are covered.
Professional Risk Assessment: Suicide and Self Harm RiskDr Gemma Russell
Presentation delivered to Lifeworks Australia as part of their professional development in 2013.
Specifically discusses how to conduct a comprehensive risk assessment and the implications for different levels of risk. Also highlights, ethical and legal responsibilities of the practitioner.
Suicide:Risk Assessment & InterventionsKevin J. Drab
Suicide: Risk and Interventions - a review of recent advances in suicidology and the use of Jobes' CAMS approach to suicide intervention and prevention.
special thanks and acknowledgement goes out to the contributors of the slide:
meroshana, haziman fauzi, griselda pearl, widad ulya, atiqah shakira, halim latiffi, farith che man and marwan omar.
Hopefully this is able to help medical students to understand about the psychiatry topic, suicide.
This is made by students so if there are any mistakes, please do correct us. We are open to constructive criticism. thank you :)
Suicide Risk Assessment and Interventions - no videosKevin J. Drab
An in depth presentation of the current information known about suicide and the most effective interventions we currently have. If you are unclear about how to handle suicidal behavior or what are the more research-based approaches this PPT will be an excellent review for you. I have been training clinicians in Suicidology for over 20 years and have always stayed on top of the latest research and literature.
Suicide, risk factors, assessment and methodological problemsDr. Amit Chougule
Seminar on Suicide from a psychiatric point of view
definition, global and indian epidemiology of suicide, risk assessment of suicide and methodological issues associated with risk assessment and suicide research are covered.
Professional Risk Assessment: Suicide and Self Harm RiskDr Gemma Russell
Presentation delivered to Lifeworks Australia as part of their professional development in 2013.
Specifically discusses how to conduct a comprehensive risk assessment and the implications for different levels of risk. Also highlights, ethical and legal responsibilities of the practitioner.
Suicide:Risk Assessment & InterventionsKevin J. Drab
Suicide: Risk and Interventions - a review of recent advances in suicidology and the use of Jobes' CAMS approach to suicide intervention and prevention.
special thanks and acknowledgement goes out to the contributors of the slide:
meroshana, haziman fauzi, griselda pearl, widad ulya, atiqah shakira, halim latiffi, farith che man and marwan omar.
Hopefully this is able to help medical students to understand about the psychiatry topic, suicide.
This is made by students so if there are any mistakes, please do correct us. We are open to constructive criticism. thank you :)
Suicide Risk Assessment and Interventions - no videosKevin J. Drab
An in depth presentation of the current information known about suicide and the most effective interventions we currently have. If you are unclear about how to handle suicidal behavior or what are the more research-based approaches this PPT will be an excellent review for you. I have been training clinicians in Suicidology for over 20 years and have always stayed on top of the latest research and literature.
A suicidal person is one who is experiencing a personal suicide crisis; that is the person is attempting suicide, is seeking a means to die by suicide, or is contemplating suicide.
Suicide: Risk Assessment and InterventionsKevin J. Drab
Suicide: Risk Assessment and Interventions; assessing suicide; suicide; killing oneself; death by suicide; indirect suicide; dynamics of suicide; self-harm; suicide survivors; psychological autopsy; commonalities of suicide; protective factors suicide; suicide risk; suicide prevention; suicide prediction; risk factors suicide; suicide risk categories; Collaborative Assessment and Management of Suicidality (CAMS) method; Suicide Status Form (SSF); motivational interviewing and suicide; Common Errors of Suicide Interventionists; contracting for safety; completed suicide; died by suicide; suicide prevention; self injury; guns and suicide
Suicide -HOW TO START A SURVIVORS GROUP-PREVENTING SUICIDE selvaraj227
HOW TO START A SURVIVORS GROUP-PREVENTING SUICIDE Etiology Risk factor for suicide Common misconceptions about suicide Suicide Prevention Nursing interventions
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
4. TERMS AND DEFINITIONS
SUICIDE: Death caused by self-directed injurious
behavior with any intent to die as a result of the
behavior.
LEGAL DEFINITION: INTENTIONAL act of self destruction
committed by someone knowing what he is doing and
the probable consequences of his action.
SUICIDE ATTEMPT: A non-fatal self-directed potentially
injurious behavior with any intent to die as result of the
behavior. A suicide attempt may or may not result in
injury.
5. INDIRECT SUICIDE:
The act of setting out on an obviously fatal course without
directly committing the act upon oneself. Indirect suicide is
differentiated from legally defined suicide by the fact that
the actor does not pull the figurative (or literal) trigger.
Examples of indirect suicide include a soldier enlisting in the
army with the express intention and expectation of being
killed in combat.
Another example would be "suicide by cop” in which a police
officer is provoked into using lethal force against them.
High risk-taking behaviors and unhealthy lifestyles may
reflect an intent to die. Studies have suggested that many
more auto accidents are some form of indirect suicide than
believed
6. PARA SUICIDE:
Suicide attempts or gestures and self-harm
where there is no result in death. It is a non-fatal
act in which a person deliberately causes
injury to him/herself or ingests any prescribed
or generally recognized therapeutic dose in
excess. Studies have found that about half of
those who commit suicide have a history of
Para suicide.
SELF-HARM (SH) OR DELIBERATE SELF-HARM
(DSH):
The intentional, direct injuring of body tissue
most often done without suicidal intentions.
The person's primary intention is to relieve
unbearable emotions, sensations of unreality,
or feelings of numbness by injuring their body.
7. SUICIDAL GESTURES
Include cutting, whereby the cut is not deep enough to cause
significant blood loss, or taking a non-lethal overdose of
medication.
Suicidal gestures are typically done to alert others of the
seriousness of the individual's clinical depression and suicidal
ideation, and are usually treated as actual suicide attempts by
hospital staff. Some suicidal gestures do lead to death, despite
the individual not having the intention of dying.
SUICIDE THREAT:
Any interpersonal action, verbal or nonverbal, stopping short
of a directly self-harmful act, that a reasonable person would
interpret as communicating or suggesting that a suicidal act
or other suicide-related behavior might occur in the near
future.
8. SUICIDAL IDEATION:
Thoughts of suicide. These thoughts can range in
severity from a vague wish to be dead to active
suicidal ideation with a specific plan and intent.
Although most people who undergo suicidal
ideation do not commit suicide, some go on to
make suicide attempts.
9. SUICIDE SURVIVOR:
A friend or family
member who has
experienced the suicide
death of someone they
cared about
10. Shneidman’s Ten Commonalities
of Suicide (1985)
1. The common stimulus is unendurable psychological pain (i.e.,
psychache).
2. The common stressor in suicide is frustrated psychological needs.
3. The common purpose of suicide is to seek a solution.
4. The common goal of suicide is cessation of consciousness.
5. The common emotion in suicide is hopelessness-helplessness.
6. The common internal attitude toward suicide is ambivalence.
7. The common cognitive state in suicide is constriction.
8. The common interpersonal act in suicide is communication of intention.
9. The common action in suicide is egression (i.e., escape).
10. The common consistency in suicide is with life-long coping patterns.
11. SUICIDE: A MULTI-FACTORIAL EVENT
Psychiatric Illness
Neurobiology
Severe Medical
Illness
Impulsiveness
Access To Weapons
Hopelessness
Life Stressors
Family History
Suicidal
Behavior
Personality
Disorder/Traits
Co-morbidity
Psychodynamics/
Psychological Vulnerability
Substance
Use/Abuse
Suicide
12. EPIDEMIOLOGY
GLOBAL SCENARIO
Over 1 million per yr
GLOBAL SUICIDE RATE – 16/100000
1.8% Deaths- due to suicide
2nd leading cause of death in youth after road traffic accidents
AGE
Comparatively rare before puberty
Males- more in 20-30yrs, after 65 yrs of age
Females- highest in middle age
Elderly & Late adolescence are at additional risk
13. Suicidal attempt - 20 times common than completed
suicide and is more common in females (completed suicide
is more common in males).
Suicidal thought - attempt – act= 100 : 10 : 1
Psychiatric illness (90%) –Depression ,Schizophrenia,
Alcoholism , Drug addiction, Organic disorders (epilepsy,
brain disease, mild dementia),Personality disorders
14.
15. GENDER DIFFERENCES
MALES
Completed rates higher
More lethal and more
violent methods used
More premeditation,
depression
Substance use more
common
Less likely to seek
professional help with
issues
FEMALES
Attempts higher
Less lethal and violent
methods preferred
More impulsive, labile
Substance use less common
More likely to seek
professional help with
issues
16. China, India and
Japan may
account for 40%
of all suicides
(WHO estimates)
17. INDIAN SCENARIO
> 10% OF SUICIDES IN THE WORLD
Suicide rate 21.1 per 100000 (2012) (67% increase over 1980 values)
1 SUICIDE EVERY 5 MIN, 1 ATTEMPT PER MIN.
242 males and 129 females commit suicide daily on an average
275 below the age of 45
Southern states - Kerala, Karnataka, Andhra Pradesh, Tamil Nadu
have a suicide rate of > 15
Northern States of Punjab, Uttar Pradesh, Bihar and Jammu-Kashmir,
the suicide rate is < 3.
71 %- <44 yrs of age
male: female ratio of 1: 0.66
18. Poisoning (36.6%), hanging (32.1%) and self-immolation
(7.9%) most common methods
Males – more of socioeconomic causes
Females-more of emotional and personal causes
Presence of suicidal thought – 5 -10% in the Indian
population.
India accounted for the highest estimated number of
suicides in the world in 2012, according to a recent
WHO report which found that one person commits
suicide every 40 seconds globally.
19.
20. According to the official data, reason for suicide is
not known for about 43% of suicides, while illness
and family problems contribute to about 44%
21. M:F = 64 :36
Boy : girl =48 : 52
More than 60% in
age group 15-
44yr.
37% in 15 - 29 yr.
34% in 30 to 44yr.
22.
23. CLASSIFICATION
DURKHEIMS CLASSIFICATION
1. EGOISTIC
High isolation, excessive individuation, not strongly integrated into
society
2. ALTRUISTIC
Excessive integration into group or society, insufficient individuation
3. ANOMIC
Experiences trauma, society changes. if bond between people
loosened, with no regulation and norms of living in society.
4. FATALISTIC
Excessive regulation, no personal freedom and hope e.g. farmer
suicide in India
24. COMMON METHODS
A asphyxiation
B blunt force trauma
C cuts, stabs
D drowning, drugs, chemicals, poisons
E electricity, explosives
F fire
G guns
H hanging, hypothermia
I intentional overdose
Pact/ cult suicides, suicide missions etc
25.
26. Mass/Family suicide –
237 cases in 2006. Max. in Chhattisgarh, then Kerala
and Rajasthan.
Govt. servant- 1.8% of total. Students 5.2%
More than 20% – by housewives.
47% married male, 25.3% married females
72.2% married, 20.7% unmarried
One-fifth of senior citizen suicide victims – belong to
Kerala.
Max. child suicide – Andhra Pradesh 14.8% (364 out of
2464)
28. PSYCHOLOGICAL
FREUD – anger turned inwards against introjected,
ambivalently cathected love object
ZILBOORG – fantasies
MENINGER- wish to die, wish to kill, wish to be
killed
KLEIN – defense mechanisms involved
GOMEZ- D/t illness
ROTJENBERG- Alternative to intense psychological
pain
JAMISON, STYRON- utter hopelessness
29. BIOLOGICAL
GENETICS
Polymorphism- in genes for tryptophan hydroxylase, MAO-A
5-HT2A receptor, 5-HTT involved
FAMILY STUDIES- Relatives of suicidal subjects have a four-fold
increased risk compared to relatives of non-suicidal
subjects
TWIN STUDIES- Twin studies indicate a higher concordance of
suicidal behavior between identical rather than fraternal
twins.
ADOPTION STUDIES- a greater risk of suicide among biologic
rather than adoptive relatives.
30. NEUROCHEMICAL/
NEUROANATOMICAL
Low CSF 5HIAA
DECREASED 5HT transporter binding in PFC
INCREASED binding post synaptic 5HT1A,2A in PFC
INCREASED CRF conc. In CSF
DECREASED CRF binding sites in frontal cortex
Decreased NE transmission in locus cereleus, decreased
neurons
32. BIOPSYCHOSOCIAL MODEL
(STRESS-DIATHESIS MODEL)
These hold that individuals who are
born with genetically modulated
tendencies toward impulsivity (the
diathesis), when stressed by
external events later in life—
particularly if they become
depressed—are more likely to harm
themselves than those not so
predisposed.
33.
34. RISK FACTORS
Demographic male; widowed, divorced, single; increases with age; white
Psychosocial lack of social support; unemployment; drop in socio-economic
status; firearm access
Psychiatric psychiatric diagnosis (es); comorbidity
Physical Illness malignant neoplasms; HIV/AIDS; peptic ulcer disease;
hemodialysis; systemic lupus erthematosis; pain syndromes;
functional impairment; diseases of nervous system
Psychological
Dimensions
hopelessness; psychic pain/anxiety; agitation; psychological
turmoil; decreased self-esteem; fragile narcissism &
perfectionism
Behavioral
Dimensions
impulsivity; aggression; severe anxiety; panic attacks;
agitation; intoxication; prior suicide attempt
Cognitive
Dimensions
thought constriction; polarized thinking; rigidity
Trauma sexual/physical abuse; neglect; parental loss; traumatic
events
Genetic & Familial family history of suicide, mental illness, or abuse
35. PROTECTIVE FACTORS
Children in the home, except among those with postpartum
psychosis
Pregnancy
Deterrent religious beliefs
Life satisfaction
Reality testing ability
Positive coping skills
Positive social support
Positive therapeutic relationship
36. PROTECTIVE FACTORS
Research has found that the following protective factors can
counterbalance suicidal vulnerabilities:
having social supports
being cognitively flexible
obtaining treatment (especially psychotropic medications)
being a younger female
being physically healthy
being hopeful
They conclude that suicidal outcome is not only a joint product of
risk, vulnerability, and psychiatric disorder, but also
counterbalanced by protection, competency, and resilience.
37. DETERMINATION OF RISK
Psychiatric Examination
Risk
Factors Protective
Factors
Specific Suicide
Inquiry
Modifiable Risk
Factors
Risk Level:
Low, Med., High
38. SUICIDE AND PSYCHIATRIC DISORDERS
Mental disorders (mainly depression and substance abuse) contribute to
more than 90% causes of suicide
MOOD DISORDERS – Risk 6-15%
Bipolar pts. – nearly 10-20% risk of suicide. Rest 10%
patients with depressive disorders commit suicide early in the illness than
later
more depressed men than women commit suicide;
single, separated, divorced, widowed, or recently bereaved.
middle-aged or older, Social isolation.
Suicide among depressed patients- likely at the onset or the end of a
depressive episode esp. in months after
Inadequate treatment
Comorbid SUBSTANCE USE disorder, psychotic depression, +ve family history
39. SCHIZOPHRENIA AND SUICIDE
10% risk. Esp. early on in the illness
Risk factors : young age, male gender, single
marital status, a previous suicide attempt, a
vulnerability to depressive symptoms, and a recent
discharge from a hospital, Personal and family
history, Living alone or not living with the family,
Higher education ,Recent loss events
Agitation, Sense of worthlessness, hopelessness,
Sleep disturbance, Fear of mental disintegration,
Poor adherence to treatment, Comorbid
Depression (recent or past), Substance
dependence, Impulsivity
40. SUBSTANCE USE AND SUICIDE
7-15% RISK
MAINLY male, middle-aged, unmarried, friendless,
socially isolated, and currently drinking, previous
suicide attempt, within a year of the patient's last
hospitalization; post discharge period, IP loss,
comorbid depression, mood disorder, ASPD
ADOLESCENTS with iv drug use
42. SUICIDE IN CHILDHOOD AND ADOLESCENCE
Rare in < 5 yrs. of age, increasing in pre-pubescence,
adolescence
Ideation more common than attempts
Impulsivity, psychiatric disorders, substance use, aggression,
poor problem solving
Copy cat suicides, internet suicides, “ werther syndrome”
Suicide more common in boys, attempts more common in
girls
risk factors in suicide include a family history of suicidal
behavior, exposure to family violence, impulsivity, substance
abuse, and availability of lethal methods
43. SUICIDE IN ELDERLY
More in males, single, widowed, divorced, living
alone, chronic illness, mood disorder
High lethality, few warning signs, greater planning
TERMINALLY ILL
MIGRANT POPULATION
44. COMPONENTS OF SUICIDE ASSESSMENT
• Appreciate the complexity of suicide / multiple
contributing factors
• Conduct a thorough psychiatric examination,
identifying risk factors and protective factors and
distinguishing risk factors which can be modified from
those which cannot
• Ask directly about suicide; The Specific Suicide
Inquiry
• Determine level of suicide risk: low, moderate, high
• Determine treatment setting and plan
• Document assessments
45. Areas to Evaluate in Suicide Assessment
Psychiatric
Illnesses
Comorbidity; Affective Disorders; Alcohol /
Substance Abuse; Schizophrenia; Cluster B
Personality disorders.
History Prior suicide attempts, aborted attempts or self
harm; Medical diagnoses; Family history of suicide /
attempts / mental illness
Individual
strengths /
vulnerabilitie
s
Coping skills; personality traits; past responses to
stress; capacity for reality testing; tolerance of
psychological pain
Psychosocial
situation
Acute and chronic stressors; changes in status;
quality of support; religious beliefs
Suicidality
and
Symptoms
Past and present suicidal ideation; plans, behaviors;
intent; methods; hopelessness; anhedonia; anxiety
symptoms; reasons for living; associated substance
use; homicidal ideation
46. Suicide Risk Categories
I. Baseline – Absence of an acute (i.e., crisis) overlay, no
significant stressors not prominent symptomatology. Only
appropriate for ideators and single attempters.
II. Acute – Presence of acute (i.e., crisis) overlay, significant
stressor(s) and or prominent symptomatology. Only
appropriate for ideators and single attempters.
III. Chronic high risk – Baseline risk for multiple attempters.
Absence of an acute (i.e., crisis) overlay, no significant
stressors not prominent symptomatology.
IV. Chronic high risk with acute exacerbation – Acute risk
category for multiple attempters. Presence of acute (i.e.,
crisis) overlay, significant stressor(s) and/or prominent
symptomatology.
47. RATING SCALES
PIERCE SUICIDE RISK SCORE
BECKS SUICIDAL INTENTION SCALE
BECKS HOPELESSNESS SCALE
MODIFIED SAD PERSONS SCALE
SUICIDE PROBABILITY SCALE
CALIFORNIA SUICIDE RISK ESTIMATION SCALE
WEISSMAN AND JORDAN RISK- RESCUE RATING
SCALE
48. SUICIDAL THOUGHTS, PLANS,
BEHAVIOR
Elicit the presence of suicidal ideation
Elicit the presence of suicide plan
degree of suicidality including intent and lethality
Consider assessing the patient's potential to harm
others in addition to him- or herself
49. GENERAL GUIDELINES FOR PRACTICE
AND TREATMENT
1. Establish a clear treatment plan with the client as to how
suicidal thoughts, feelings, and behaviors will be managed
on an outpatient basis.
2. Closely monitor and document ongoing suicidality until it
resolves.
3. Consider and use all appropriate modalities (e.g., various
therapies: CBT, DBT, EMDR, Behavioral Activation Therapy,
journaling, exercise, couples counseling, bibliotherapy),
vocational counseling, medication, etc.
4. Routinely seek professional consultation and document
such.
5. Document the resolution of suicidality; monitor for any
future reoccurrence.
50. SOMATIC TREATMENTS
ECT Evidence for short-term reduction of suicide
Benzodiazepines May reduce risk by treating anxiety
Antidepressants A mainstay treatment of suicidal patients with
depressive illness / symptoms.
Lithium and
Anti-convulsants
Lithium has a demonstrated anti-suicide effect;
anticonvulsants not so much
Antipsychotics Evidence for Clozapine reducing suicidality in
schizophrenia and schizo-affective disorders
51. PSYCHOTHERAPY
CBT, PROBLEM SOLVING
DIALECTICAL
GROUP THERAPY
SHORT TERM
INTERPERSONAL
PSYCHOANALYTICAL
52. FOLLOW UP ESSENTIAL,
DOCUMENTATION ESSENTIAL
LEGAL ASPECTS –
firearm control legislation, restrictions on pesticides, restrictions on the
prescription and sale of barbiturates and other medications
SUICIDAL ATTEMPT ILLEGAL ( SEC 309 IPC)
ABETTMENT OF SUICIDE PUNISHABLE (SEC 306 IPC)
SUICIDE HELPLINES- AASRA, SAMARITAN, SNEHA
SUPPORT GROUPS, NO SELF HARM CONTRACTS
DECREASED MEDIA SENSATIONALISATION
53. WHEN A SUICIDE OCCURS
Despite best efforts at suicide assessment and
treatment, suicides can and do occur in clinical
practice
Approximately, 12,000-14,000 suicides per year occur
while in treatment.
To facilitate the aftercare process:
Ensure that the patient’s records are complete
Be available to assist grieving family members
Remember the medical record is still official and
confidentiality still exists
Seek support from colleagues / supervisors
54. COLLABORATIVE ASSESSMENT &
MANAGEMENT OF SUICIDALITY (CAMS)
METHOD
Developed by Dr. David Jobes (2006).
A specific clinical approach and a philosophy of working with suicidal clients.
The CAMS approach conceptualizes the assessment and treatment of suicidal
patients in a fundamentally different way than current conventional approaches.
CAMS is inherently designed to help shift clinicians’ attitudes and approaches by
changing our conceptualization of suicide as a clinical problem and thereby
changing how we assess and treat this problem.
CAMS approach does not focus on alleviating problems like depression, but rather
concerns itself with suicidality. By maximizing alliance and motivation CAMS assists
the client to develop coping and problem-solving skills to make suicide an
unnecessary option.
The core multipurpose tool used in all phases of the CAMS is the Suicide Status Form
(SSF).Use of the SSF within CAMS enables both parties to examine and work with
the client’s suicidality in a relatively objective manner.
55. NOTE ON CONTRACTING FOR
SAFETY!!!
The concept of contracting for safety (also known as no-suicide
contracts or agreements, no-harm contracts, and suicide prevention
contracts), although a popularly accepted method for managing
suicidal patients for more than 30 years, has no scientific evidence to
support its effectiveness.
At times, contracting is often the primary factor in clinical decision-making,
justifying a lower level of intervention or concern.
The ultimate focus of suicide contracting is not on the safety
agreement itself but on the process it engenders to engage staff and
patient in a dynamic, meaningful relationship for identifying patient
needs, encouraging disclosure of distress, and assuring consistent
support and appropriate interventions.
58. AREAS OF FOCUS
• Education and awareness programs for the general
public and professionals
• Screening methods for high-risk persons
• Treatment of psychiatric disorders
• Restricting access to lethal means
• Media reporting of suicide.
59.
60. •WHO DECLARED THE FIGHT
AGAINST SUICIDE AS A
PRIORITY FOR THE FIRST
TIME IN THE YEAR 2000.
61. Suicide Prevention
(SUPRE) Project - WHO
By WHO Dept. of Mental Health and
Substance Abuse (1999).
Objectives-
1. To reduce mortality/morbidity due to
suicidal behavior.
2. To break taboo surrounding suicide.
3. To bring together national authorities and
public.
62. WORLD SUICIDE PREVENTION
DAY
• Efforts to prevent suicide have been celebrated on World Suicide
Prevention Day – September 10th – each year since 2003.
• In 2014, the theme of World Suicide Prevention Day is 'Suicide
Prevention: One World Connected.'
• The theme reflects the fact that connections are important at
several levels if we are to combat suicide.
• World Suicide Prevention Day in 2014 is significant because it
marks the release by the WHO of the World Suicide Report (WSR).
The report follows the adoption of the Comprehensive Mental
Health Action Plan 2013-2020 by the World Health Assembly,
which commits all 194 member states to reducing their suicide
rates by 10% by 2020.