This document discusses using echocardiography to measure stroke volume and cardiac output in ICU patients. It explains that stroke volume and cardiac output can provide early warning of circulation failure beyond what mean arterial pressure indicates. The document outlines how to obtain echocardiography images of the heart and left ventricle outflow tract to measure stroke volume using pulsed-wave Doppler. Stroke volume combined with heart rate can then be used to calculate cardiac output. Measuring stroke volume allows assessment of the effectiveness of fluid challenges, inotropes, or other therapeutic maneuvers.