Guide catheters are essential tools for Pecutaneous
Coronary Intervention
• Understanding construction, design & performance
characteristics facilitate their appropriate selection
• Selection of Guide catheters seems elementary but
makes the difference between a successful and failed
PCI procedure
Diagnostic catheters for coronary angiography Aswin Rm
Overview of diagnostic catheters used in coronary angiography
Guide catheters not included
History of coronary catheters
Radial techniques and catheters
Diagnostic catheters for coronary angiography Aswin Rm
Overview of diagnostic catheters used in coronary angiography
Guide catheters not included
History of coronary catheters
Radial techniques and catheters
Ionizing Radiation -How is Gray different from Sievert -Deterministic & Stochastic Radiation Risks -Air Kerma-Time, Distance and Shielding Principles -Dosimetry
Although the risks of coronary angiography have declined over the years by increased clinical experience and advanced technologies, it still requires attention, knowledge and experience due to being an interventional diagnostic method. A safe coronary angiography begins with the selection of the appropriate catheter for the anatomical structure of the patient and the evaluation of the pressure when the catheter is placed in the coronary ostium. Coronary pressure waves are complementary requirements of angiography. The recognition, evaluation and precautions to be taken for abnormal pressure waves directly affect the mortality of the patient. One of the first clues to the presence of stenosis in the left main coronary artery (LMCA) is abnormal changes in pressure when the catheter is seated in the ostial LMCA. This often occurs as a “ventricularization” or “damping”. For decades, ventricularization was mostly experienced as a stenosis by invasive cardiologists [1]. Recognition of abnormal changes in pressure and precautions to be taken prevent catastrophic outcomes in patients
https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000518.pdf
For more open access journals in Crimson Publishers
please click on https://crimsonpublishers.com/
For more articles in open journal of Cardiology & Heart Diseases
please click on https://crimsonpublishers.com/ojchd/
This is a comprehensive description of coronay lesion assessment from routinely used angiography to advanced imaging modalities like IVUS/OCT including their functional significance by FFR
rotablation is procedure used in complex pci with heavily calcified lesion for adequate expansion of stent.if used in indicated case and well aware of contraindication is necessary for achieving good results.
Ionizing Radiation -How is Gray different from Sievert -Deterministic & Stochastic Radiation Risks -Air Kerma-Time, Distance and Shielding Principles -Dosimetry
Although the risks of coronary angiography have declined over the years by increased clinical experience and advanced technologies, it still requires attention, knowledge and experience due to being an interventional diagnostic method. A safe coronary angiography begins with the selection of the appropriate catheter for the anatomical structure of the patient and the evaluation of the pressure when the catheter is placed in the coronary ostium. Coronary pressure waves are complementary requirements of angiography. The recognition, evaluation and precautions to be taken for abnormal pressure waves directly affect the mortality of the patient. One of the first clues to the presence of stenosis in the left main coronary artery (LMCA) is abnormal changes in pressure when the catheter is seated in the ostial LMCA. This often occurs as a “ventricularization” or “damping”. For decades, ventricularization was mostly experienced as a stenosis by invasive cardiologists [1]. Recognition of abnormal changes in pressure and precautions to be taken prevent catastrophic outcomes in patients
https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000518.pdf
For more open access journals in Crimson Publishers
please click on https://crimsonpublishers.com/
For more articles in open journal of Cardiology & Heart Diseases
please click on https://crimsonpublishers.com/ojchd/
This is a comprehensive description of coronay lesion assessment from routinely used angiography to advanced imaging modalities like IVUS/OCT including their functional significance by FFR
rotablation is procedure used in complex pci with heavily calcified lesion for adequate expansion of stent.if used in indicated case and well aware of contraindication is necessary for achieving good results.
Interventional Radiology : Devices and Embolic Agents that a Resident NEEDS T...Saurabh Joshi
Interventional Radiology is full of various devices and materials. The general radiology resident needs to know these in order to impress the examiner. This file also contains information on various embolic agents.
Rapid fire Tipps and Tricks – 5 min: What do do if …microcatheter cannot pass...Euro CTO Club
Rapid fire Tipps and Tricks – 5 min: What do do if …microcatheter cannot pass collateral
Jo Dens, Belgium
The Experts “Live” Workshop 2017
Saturday, September 16th, 2017
This presentation provides sufficient material for anyone who wants is interested in interventional radiology. Here we will discuss the available facilities, mechanisms and equipments.
In my opinion this presentation will prove a footstep in interventional radiology
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
Struggling with intense fears that disrupt your life? At Renew Life Hypnosis, we offer specialized hypnosis to overcome fear. Phobias are exaggerated fears, often stemming from past traumas or learned behaviors. Hypnotherapy addresses these deep-seated fears by accessing the subconscious mind, helping you change your reactions to phobic triggers. Our expert therapists guide you into a state of deep relaxation, allowing you to transform your responses and reduce anxiety. Experience increased confidence and freedom from phobias with our personalized approach. Ready to live a fear-free life? Visit us at Renew Life Hypnosis..
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
4. Diagnostic Catheter Guide Catheter
Thicker shaft Thinner shaft
Internal Dm Small Internal Dm Larger
Tapering Tip Non Tapering Tip
Less Reinforced More Reinforced
Difference between Diagnostic & Guide Catheter
9. Diagnostic catheter shapes
•Femoral –Judkins - JL4, JR4
– large JL5
– Small JL3.5
– Other - Williams, AL1
•Radial
–Judkins - JL3.5, JR4 - Tiger
Summary
10. The Guiding Catheter
A special large-lumen catheter (5–8F) is used to deliver the
coronary balloon catheter and other interventional devices
to the target lesion.
11. •Support for device advancement
•Path for device and wire transport
• Vehicle for contrast injection
• Measurement of Pressure
Functions of a Guide Catheter
12. Parts of a Guiding Catheter
Usual Length is 100 cm
Tertiary curve is available in some Catheters
13. Guiding catheters are made up of three layers
Inner polytetrafluoroethylene layer that is slippery,
A middle stainless steel braided layer.
Outer soft nylon elastomer jacket
Cross section of catheter
14. Guide Selection
The guide catheter is usually firmly supported against the aortic
wall opposite to the coronary sinus from which the artery arises.
Selection is dependent on
•Side holes
•French sizes[Fr]
•Length
•Type of curve
Anatomy based
Size of the aortic root
Ostial origin and takeoff
•Support
Active Support
Passive Support
• Anomalous origin
15. Side Holes
Side holes prevent ventricularization or dampening caused by engagement
of guide significant ostial lesions, misalignment of guides, during coronary
spasm, or when a large Fr guide is used for engagement of a smaller coronary
artery
Advantages Disadvantages
Maintains
coronary
artery
perfusion
False sense of security as it monitors
aortic not coronary
pressure
Suboptimal opacification
Increase in contrast volume
TERUMO-Climber TM
16. French Sizes
Ideally use the smallest diameter catheter feasible to minimize the risk of arterial
damage.
Larger French catheters have the advantage of improved opacifi cation, better guide
support and allow for pressure.
•Usually 6 Fr guides will suffice for most interventions.
•7 Fr: Two-stent strategy for bifurcation lesions and rotational atherectomy burr of 2
mm.
Guide Length
•Regular 110 cm guides will suffi ce for most coronary interventions.
•Long saphenous vein graft (SVG) or internal mammary artery (IMA) grafts
interventions may require the use of short 80 or 90 cm guides
19. Curve length = distance between P
(primary curve) & S (secondary curve)
•Aortic diameter determines the curve length
Aortic width
20. GUIDE CATHETERS FOR TRANSFEMORAL INTERVENTION
Most common catheters
– Judkins
– Amplatz
– Extra Backup support
EBU (Medtronic)
XB (Cordis)
Voda, Qcurve (Boston)
• Catheters with niche use
– Multipurpose – RCA graft, High LM takeoff
– IMA cath –
LIMA, Superior takeoff RCA or RCA graft
– LCB, RCB cath – SVG
21. JL – primary (35°) Secondary(180°) and tertiary
(35°)curve fitting aortic root anatomy engages
LMCAostium without muchmanipulation
JR – requires clockwiserotation to engage RCA
Judkins
23. The Amplatz Guide
•Secondary curve rest against the noncoronary
posterior aortic cusp
•Offers firm platform for advancement of device
• Best in the case of a short LM, with downgoing
left circumflex artery (LCX)
•Tip points slightly downward -higher danger of
ostial injury causing dissection
24. The Amplatz Guide
• Selection of the proper size for an Amplatz guide is essential
– Size 1 is for the smallest aortic root
– size 2 for normal
– size 3 for large roots
• Attempts to force engagement of a
preformed Amplatz guide that does not
conform to a particular aortic root
increase risk of complication
• If tip does not reach the ostium and keep
lying below it - guide is too small
• If tip lies above the ostium - guide is too
large
• When RCA ostium is very high - left
Amplatz guide may be used to engage
the right ostium
25. Long tip catheters (Extra Support)
• Voda, XB, EBU
• Advantages
– coaxial intubation
– better support & stability due to large area of contact between
catheter & contralateral aortic wall
– precise control and manipulation
– lack of bends
– improve advancement of devices,decrease the loss of supportive
forces
–Safety
26. Extra-Back-Up Guide
• Long tip forms a fairly straight line
with the LM axis or the proximal
ostial RCA
• Long secondary curve - abut the
opposite aortic wall
• So tip in the coronary artery is not
easily displaced
•Provide a very Stable platform
27. Multipurpose Guide
• Straight with a single minor bend at the tip
• For RCA bypass graft or a high left main (LM) takeoff
28. Other catheters
3 DRC –
Three dimensional right curve - for tortuous, bent anatomy and
posterior or superior take off of RCA
• Arani
• Double angle 90° curve sits on ascending aorta in S
configuration and is therefore useful for RCA with horizontal take-
off & shepherd crook RCA
•Primary and secondary curve provides two contact points on the
opposite side of aorta thus providing tremendous back-up
29. • El Gamal (EGB) - pre-shaped catheter with improved distal end-portion for accessing
bypass grafts and more precise access of RCA
• LCB - for left coronary venous bypass grafts. Its tip has 90 º bend with 70º secondary
bend.
• RCB - for right coronary venous bypass grafts, its tip and secondary bends
approximate 120º - like a JR catheter with ashallower tip bend
Other catheters
41. Guidewires:
•Guidewires (solid wires navigated within the vascular system / extra‐ vascular tract)
act as a lead point for catheters, allowing operators to traverse along a given vessel / track.
•General Types of Guidewires:
•Starting guidewires ‐ used for catheter introduction and some procedures.
•Selective guidewires ‐ used to cannulate side branches or cross critical lesions.
•Exchange guidewires ‐ are stiffer and used to secure position as devices are passed over the
wire.
42. Length
•Must be long enough to cover the distance both inside and outside the patient.
•Must also account for access well beyond the lesion, so that access across the
lesion will not be lost intraoperatively.
•Usually varies from 145 to 300 cm.
Diameter
•Vascular catheters are designed with a guidewire port of specific diameter.
•Most procedures are performed with O35 guidewires (0.035 in.).
•Small‐vessel angiography requires 0.018–0.014 in. guidewires.
43. Purpose of the Guide wire
• To access the lesion
• To cross the lesion atraumatically
• To reach far end of the vessel
• To rail the devices into coronaries
• To provide support for interventional devices
44. Components of Coronary Guide wire
Core
Tip
Cover
Core Material
• Stainless steel (SS): Strengths : provide optimal
support, transmission of force, torque
characteristics, But susceptible to kinking
•Nitinol :More Flexible & kink resistance But less
torqueability than SS.
Core Diameter
Larger the Diameter Better the support & torqueability.
Core Taper
Continous or segmental
Shorter tapers enhance the push force & pushability ,
while longer tapers enhance the flexibility
Coronary
Guide wire
45. Components of Coronary Guide wire
Core
Tip
Cover
The tip refers to the distal end of the guidewire.
There are two types of tips.
covered with coils (spring-tip guidewires)
polymer (polymer-tip guidewires)
2 type Of Design
Core to TIP Design- one-piece core where the core
extends all the way to the tip with a variable taper
Two-piece or shaping ribbon The core stops just
before the distal tip. A shaping ribbon (a small piece of
metal) bridges the gap between the end of the core and
the distal tip
(these wires have less reliable torque control)
and a higher likelihood to prolapse.
Coronary
Guide wire
46. Components of Coronary Guide wire
Core
Tip
Cover
To maintain the overall diameter of 0.014 in., all
guidewires have a specifi c surface coating:
Hyderophobic
Hydrophobic coatings are silicone based coatings which
repel water and are applied on the working length of the
wire, with the exception of the distal tip
Advantages
More controllable (and therefore less likely to dissect) •
Provide better tactile feel
Challenges
• Poor trackability
• Wire tip becomes stiffer, torque response increases,
but less tip resistance is transmitted to the operator,
making it easier to enter a false channel.
Coronary
Guide wire
47. Components of Coronary Guide wire
Core
Tip
Cover
Hydrophilic Coating
Applied over the entire working length of wire including
tip coils
• Attracts water - needs lubrication
• Thin, non slippery, solid when dry→ becomes a gel
when wet
– ↓friction
– ↑trackability
– ↓Thrombogenic
– ↓tactile feel
– ↑risk of perforation
Useful in negotiating tortuous lesions and in “finding
microchannels” in total occlusionschannel.
Coronary
Guide wire
48.
49. The Amplatz super-stiff and ultra-stiff guide wires (Cook
Medical, Bloomington, Indian are the mainstay for almost
every case in stabilizing balloons across high-flow lesions
and during stent implantation or valvuloplasty
Different type of Guidewire & Their Uses
(0.025 to 0.038 inch)
coronary wires are important to have on hand to engage
coronary fistulas and small tortuous arterovenous
malformations.
(0.014 inch)
The Meier Backup wire (Boston Scientific) and Lunderquist
extra stiff wire (Cook Medical) have been invaluable for transcatheter
pulmonary and aortic valve implantation when tortuosity
and calcification is a problem.
50. Guidewire Depend upon the Shapes of the Distal end
Wires with various sized curves. The distal 1- to 20-cm end of a wire is often
distinct in design and maneuverability from its remaining length; this end often
determines a wire’s utility.
52. Selection of Guidewires
The selection of a guidewire should be primarily determined by
• Vessel morphology
•Lesion morphology
•Device properties.
53. Guidewires for Standard Lesion Morphology
A standard lesion is defi ned by the absence of complex
characteristics A “workhorse or frontline” wire is most suitable for
standard lesions. The workhorse wire, which accounts for about 70
% of all coronary wires used, is a fl oppy wire with atraumatic tip
which provides low to moderate support.
Guidewires for Chronic Total Occlusions
For the more complex lesions, particularly chronic total occlusions
(CTO), a stiffer wire with increasing support may be required.