This document discusses stress, its causes, effects, and management. It defines stress as the mental and physical response to changes and challenges in life. Stress can be positive (eustress) or negative (distress) depending on its intensity and duration. The body's main response pathways to stressors are the neuroendocrine-immune pathway and the sympathetic nervous system pathway. Chronic stress can lead to illnesses through prolonged activation of these pathways. Stress management techniques include changing one's thinking, behaviors, and lifestyle through relaxation, exercise, diet, and other alternative therapies.