The document discusses trade routes between 500-1500 CE. It focuses on the Silk Roads between China and Europe, the Indian Ocean sea routes, and trans-Saharan land routes. Along these routes, goods like silk and spices were traded, religions spread, and diseases transmitted. Merchants accumulated wealth and cities like Srivijaya rose to prominence by controlling strategic choke points. West Africa developed larger states and cities due to trans-Saharan trade and the influence of Islam. Networks of interaction differed in the Americas, being oriented north-south and within civilizations rather than between them like in Eurasia.