The document discusses various aspects of producing and manufacturing capsules. It provides 20 multiple choice questions about capsule production processes like the treatment used for gelatin solubility, machines used to fill capsules, sealing temperatures, capsule sizes, difficulties with hygroscopic powders, ratio of gelatin to glycerin used, volume filled by different sizes, shell materials, gelatin properties, drying methods, hardness testing instruments, and capsule production methods.

1. SOLID GAME
Harishankar Sahu
Naresh Mali
Neha Bala
Vibha

2. 1. Which treatment is used for
solubility of gelatin ?
(a) Heat
(b) Formalin
(c) Water
(d) Alcohol

3. 2. Which of the following is used
to fill powdered dry solid into
soft gelatin capsule?
(a) Aceo gel
(b) Rotobil
(c) Rotosort
(d) Rotoweigh

4. 3. Sealing of capsule is
achieved by
(a) 100oC
(b) 20oC
(c) 37oC- 40oC
(d) 70oC

5. 4. Empty capsule has moisture
content in the range of-
(a) 60%
(b) 12%-15 %
(c) 50%- 70%
(d) 30%

6. 5. What is smallest size of
capsule ?
(a) 000
(b) 0
(c) 2
(d) 5

7. 6. What are the difficulties
associated with hygroscopic
powder in Capsules ?
(a) Cracking
(b) Sealing
(c) Capping
(d) Sticking

8. 7. Rotasort is the machine used
to sort out?
(a) Sealed ampules
(b) coated tabled
(c) Filled capsules
(d) sealed container

9. 8. Gelatin and glycerin are is
used in what ratio in capsules ?
(a) 10:1
(b) 9:1
(c) 1:1
(d) 5:1

10. 9. In Capsules, ROTAFIL is used
for filling -
(a) Liquids
(b) Pellets
(c) Powder
(d) Corrosive liquid

11. 10. The 000 size capsule can fill
the volume-
(a) 0.5ml
(b) 1.36 ml
(c) 1.0 ml
(d) 0.25 ml

12. 11. Vegetable capsule shell are
prepared from-
(a) Gelatin
(b) HPMC
(c) Chitosan
(d) None of Above

13. 12. Gelatin is ?
(a) Fat
(b) Protein
(c) Carbohydrate
(d) None of above

14. 13. High bloom strength gelatin
is used in manufacture of ?
(a) Soft
(b) Hard
(c) A & B
(d) A

15. 14. The shell of soft gelatin
capsule may be made elastic or
plastic –like the addition of ?
(a) Sorbitol
(b) Povidone
(c) PEG
(d) HPMC

16. 15. The following steps are
followed in producing hard
gelatin shell________?
(a) Dipping and Spinning
(b) Spinning and Trimming
(c) A and Trimming
(d) Kipping

17. 16. Capsule are should be stored
at ____ and ____ humidity level.
a) dry , low
b) dry , high
c) cool , high
d) cool , low

18. 17. The hard Galeton capsule are
produced by mechanical dipping of
_______ of desire able shape and
diameter.
a) pins
b) pegs
c) both a & b
d) none of above

19. 18. Drying of soft capsule shell
is done is by -
(a) Truck drying
(b) Fluid bed drying
(c) Vacuum Drying
(d) Microwave Drying

20. 19. Name of the given
instrument-
(a) Rockwell Hardness Tester
(b) Pfizer Hardness Tester
(c) Vickers Hardness Tester
(d) Brinell hardness Tester

21. 20. Most soft gelatin capsules are made
using a
(a). Rotary die process
(b). Reciprocating die process
(c) Oscillating die process
(d). Bubble method
(e). None of the above