The document summarizes key events and concepts around European exploration between the 15th and 16th centuries. It discusses how the Renaissance led to advances in science and technology like navigation tools. Spain sponsored Columbus' 1492 expedition seeking a western route to Asia. Later, Magellan led the first expedition to circumnavigate the globe, and Spain and Portugal divided colonial claims in the Americas through a treaty. The Aztec Empire was conquered by Cortez, and missionaries came to convert native peoples to Catholicism. Other European nations like France also engaged in exploration, as Jacques Cartier searched the St. Lawrence River.