Six Sigma is a data-driven methodology for improving processes by eliminating defects. It aims for nearly flawless processes, with 99.99966% of all opportunities operating without defects. Six Sigma follows the DMAIC model, consisting of five phases - Define, Measure, Analyze, Improve, and Control. The goal is to reduce variation and maintain consistent, high-quality output through a problem-solving approach focused on addressing root causes of defects.