The Silk Road established connections between China and Western Europe from 200 BCE to 1450 CE, facilitating trade of goods, technologies, cultures, and diseases across empires. While powerful empires like Han China and Western Rome experienced prosperity through Silk Road trade, their eventual declines in the 5th and 6th centuries disrupted commerce. However, new powers like the Eastern Roman Empire, Islamic Caliphate, and Chinese dynasties restored trade routes. Over the centuries, cultural exchanges along the Silk Road also spread ideas and innovations that impacted navigation, mathematics, and exploration. Despite many empires and political changes, the Silk Road continued functioning as a conduit for exchange across Eurasia for over 1600 years.