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28/11/2014CRITICAL CARE
1
DEPARTMENT OF NURSING
DONE BY: RN, BSc.N ABDULLA K NGWALI
SECOND YEAR,
SEMISTER ; 1
LECTURE; RAHMA JARUFE
TOPIC
28/ 11/ 2014CRITICAL CARE2
TOPIC: CARDIOVASCULAR
SYSTEM
SUB TOPIC: SHOCK
28/11/2014CRITICAL CARE3
Learning objectives’-
28/11/2014CRITICAL CARE4
 At theend of thissession every leaner should
beableto understand thefollowing:-
 Define shock
 List thestageof shock
 Describetypesof shock with its causes, sign
 and symptoms.
 Explain thepath physiology of shock
 List sign & symptomsof theshock in general.
 Mention thecomplication of shock.
 DescribeManagement & treatment of shock
Definition
 Shock isaseriousmedical condition where
thetissueperfusion isinsufficient to meet
demand for oxygen and nutrition becausethe
body isnot getting enough blood flow.
Shock often accompaniessevereinjury /
illness.
OR
 Isalifethreatening condition that occurs
when thebody isnot getting enough blood
flow.
Zanzibar university
continue
28/11/2014CRITICAL CARE6
OR
 Isasudden fall in theblood passing through the
tissuesof thevital organ.
STAGE OF SHOCK
28/11/2014CRITICAL CARE7
 Thefollowing stageincreaseyour chancesof
developing shock:
(a) “PRE- SHOCK”
(b) SHOCK
(c) “END ORGAN DYSFUNCTION”
Continue
28/ 11/ 2014CRICAL CARE8
(a) “PRE- SHOCK”
Body isableto compensatefor decrease
perfusion up to 10% reduction n blood volume.
continue
28/11/2014CRITICAL CARE9
(b) “SHOCK”
Compensatory mechanism overwhelmed see
signs(symptomsof organ dysfunction) 20-25%
reduction in blood volume.
(c) “ENDORGAN DYSFUNCTION”
Learning to irreversibleorgan damageor death.
Types of shock
28/11/2014CRITICAL CARE10
 Shock can bedivided into:
A. Hypovolemic shock
B. Cardiogenic shock
C. Obstructive shock
D. Distributiveshock
They are;-
( !) Sepsis
(2) Neurogenic (spinal shock)
(3) Anaphylaxis
(4) Electricity
(A). Hypovolemic shock
28/11/2014CRITICAL CARE11
 Hypovolemic shock (caused by inadequate
blood volume)
Hypovolemic shock isan emergency condition in
which severeblood and fluid lossmakestheheart
unableto pump enough blood to thebody.
Thistypeof shock can causemany organsto stop
working.
28/ 11/ 2014CRITICAL CARE12
 Itsprimary causeishemorrhagedueto trauma
(internal and/or external), or lossof fluid from the
circulation and vomiting and diarrhea arethe
most common causein children.
With other causesincluding burns.
Cause of hypovolemic shock
SIGN AND SYMPTOMS
28/11/2014. CRITICAL CARE13
 A rapid, weak, thread pulsedueto decreased
blood flow combined with tachycardia.
 Cool, clammy skin due to stimulation of
vasoconstriction.
 Rapid and shallow breathing dueto sympathetic
nervoussystem stimulation and acidosis
Continue
28/11/2014CRITICAL CARE14
Hypothermia dueto decreased perfusion and
evaporation of sweat.
Thirst and dry mouth, dueto fluid depletion.
{B} Cardiogenic shock
28/11/2014CRITICAL CARE15
Cardiogenic shock isadiseasestatewherethe
heart isdamaged enough that it isunableto
supply sufficient blood to thebody.
Sign and symptoms
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 Distended jugular veins dueto increased
 jugular venouspressure.
 Weak or absent pulse.
 Arrhythmia often
 Tachycardia.
CAUSES OF CARDIOGENIC SHOCK
28/11/2014CRITICAL CARE18
 Cardiogenic shock iscaused by thefailureof the
heart to pump effectively.
 Thiscan bedueto damageto theheart muscle,
most often from alargemyocardial infarction.
 Cardiomyopathy /myocarditis
 Congestiveheart failure(CHF)
 Cardiac valve problems.
OBSTUCTIVE SHOCK
 Isdueto obstruction of blood flow outsideof
theheart.
Several conditionscan result in thisform of
shock.
01/09/15CRITICAL CARE19
Causes of obstructive shock
 Cardiac tamponade in which fluid in thepericardium
preventsinflow of blood into theheart (venousreturn).
Constrictivepericarditis in which thepericardium shrinks
and hardens, issimilar in presentation.
 Tension pneumothorax Through increased intrathoracic
pressure, blood flow to theheart isprevented (venous
return).
01/09/15CRITICAL CARE20
continue
 Pulmonary embolism istheresult of a
thromboembolic incident in theblood vesselsof
thelungs and hindersthereturn of blood to the
heart.
 Aortic stenosishinderscirculation by
obstructing theventricular outflow tract.
01/09/15CRITICAL CARE21
Sign and symptoms of
obstructive
Low blood pressure
Lack of oxygen to body tissue
Clammy skin
Cool skin.
01/09/15CRITICAL CARE22
{C} DISTRIBUTIVE SHOCK
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Isdueto impaired utilization of oxygen and thus
production of energy by thecell.
Distributiveshock includethefollowing;-
 Septic
 Anaphylactic,
 Neurogenic,
 Electricity
Causes of distributive shock
 It can becaused by;-
 Systematic Inflammatory ResponseSyndrome
(SIRS)
 Dueto conditionsother than infection such as
pancreatitis,burns, or trauma.
01/09/15CRITICAL CARE24
continue
 Toxic Shock Syndrome(TSS)
 Anaphylaxis(A sudden ,severeallergic reaction)
 Reactionsto drug or toxins.
 Hepatic (Liver) insufficiency and damageto the(
CNS)
01/09/15CRITICAL CARE25
Sign and symptoms of
distributive
Temperature<36 OR > 38
Heart rate>90 beatsper minutes
Respiratory Rate>20bmin
01/09/15CRITICAL CARE26
{a} SEPTIC SHOCK
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 Septic shock ( associated with infections)
Septic shock isaseriouscondition that occurs
when an overwhelming infection leadsto low
blood pressureand low blood flow.
Thebrain, heart, kidneys, and liver may not work
properly or may fail.
Continue
28/11/2014CRITICAL CARE28
CAUSES OF SEPTIC
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 Septic shock can becaused by ;-
1) Gram negative
 Bacteriasuch as(among others) Escherichia
co li, Proteusspecies, klebsiela, pneumo niae which
releasean endotoxin which produces adverse
biochemical,
 Immunological and occasionally neurological
effects which are harmful to the body.
Continue
28/ 11/ 2014CRITICAL CARE30
2) Gram-positive
 Cocci such aspneumococci and
 Streptococci and certain fungi aswell asGram-
positive
bacterial toxins.
 Septic shock also includessomeelements of
cardiogenic shock.
Symptoms of septic
shock
 Symptomsare:
similar to hypovolaemic shock except in thefirst
stages:
Pyrexiaand fever, or hyperthermia, dueto
overwhelming bacterial infection.
 Vasodilation and increased cardiac output due
to sepsis.
01/09/15CRITICAL CARE31
(b) Anaphylactic shock
28/11/2014CRITICAL CARE32
 Is a type of severe hypersensitivity or allergic
reaction.
28/ 11/ 2014CRITICAL CARE33
causes
28/11/2014CRITICAL CARE34
 Causesinclude;-
 Allergy to insect stings, medicines, or foods
(nuts, and seafood), etc.
Sign and symptoms of anaphylactic
 Polyuria,
 Respiratory distress, hypotension (low blood
pressure),
 Encephalitis, fainting, unconsciousness,
 Urticaria(hives),
 Angioedema(swelling of thelips, face, neck
and throat), Tears(dueto angioedemaand stress),
 Vomiting, itching,
 Anxiety,
01/09/1535
CRITICAL CARE
(d) Electrical Shock
28/11/201436
 Isthephysiological reaction or injury caused by
electric
current passing through thehuman body.
OR
 An electric current that passesthrough thebody is
also called ashock.
 And it can beso dangerous but electrical
shock isdifferent from themedical shock
discussed .
continue
28/ 11/ 2014CRITICAL CARE37
Continue
28/11/2014CRITICAL CARE38
In electric shock Oxygen isroutinely given, to the
victim and somepeopleneed to beput on a
ventilator (abreathing machine) to increasethe
amount of oxygen getting to their cells.
Causes
Electrical causecan causeinjuriesincluding
burnsand disturbancesto heart rhythm
(heart failure) that could befatal.
01/09/15critical care39
Sign and symptoms
 Unconsciousness.
 Burns, particulary entranceand exit burns(
wheretheelectricity entered and left thebody.)
 Difficult in beathing or n breathing at all.
 Sudden onset of cardiac arrest.
01/09/15CRITICAL CARE40
PATHOPHYSIOLOGY OF SHOCK
Cellsswitch from aerobic to anaerobic metabolism
Lactic acid production
Cell function ceasesand swells
Membranebecomesmorepermeable
Electrolytesand fluidsseepsin &out of cell.
01/09/15CRITICAL CARE41
continue
Na and K pump impaired
01/09/15CRITICAL CARE42
Mitochondria damage cells death
28/ 11/ 2014CRITICAL CARE43
Sign and symptoms in general types
 ) Rapid respiration
2) Cold and clammy skin,
3) A weak but rapid pulse,
4) Fall in blood pressure, dueto reduction of blood
volume
 5) Weaknessall over thebody.
6) Dizzy, confused, and may becomeunconscious.
Intensivethirsty dueto lossof water
01/09/1544
GENERAL COMPLICATION OF SHOCK
28/1/2014CRITICAL CARE45
 Kidney disease
 Liver disease
 Intestinal ischemia
 Stroke
 Disseminated intravascular coagulation (DIC)
Continue
28/11/2014CRITICAL CARE46
 Respiratory failure
 Heart failure
 Death
Managements and Treatments
shock
28/11/2014CRITICAL CARE47
 Airway
 breathing
 Circulation
 Treatmentsof shock alwaysshould beaimed to
correct thecauseof shock and helping
physiological compensatory mechanism to restore
thetissueperfusion.
continue
 Themain goalsof thetreatment of cardiogenic
shock arethere-establishment of circulation to the
myocardium, minimising heart muscledamageand
improving theheart’seffectivenessasapump.
 Oxygen (O2) therapy to reducestheworkload
of theheart by reducing tissuedemandsfor blood
flow.
 Administration of cardiac drugs
01/09/15CRITICAL CARE48
Continue
 Increaseheart’spumping action and decrease
work load of theheart through medication such as
Dopamine, dobutamine, epinephrine,
norepinephrine.
 Nitroglycerineuseful only if cardiogenic shock
accompanied by appropriate
 Dosage10mg-min 6ml-hr increaseby 10mg –
min every 5-10min to achieveoptimal effect.
01/09/15CRITICAL CARE49
Continue
28/11/2014CRITICAL CARE50
 So dueto thisreason shock istreated dueto
under lying causesof it if whether ishemorrhagic,
or Hypovolemic or anaphylactic
 In all typesof shock restoration of arterial
pressureisessential to maintain perfusion and
blood flow to thebrain.
continue
28/11/2014CRITICAL CARE51
 Peoplein shock should betaken by ambulance
to ahospital asquickly aspossible. then, they
should bekept lying down on their back with their
feet raised about afoot higher than their head.
 Administer counter-mediatorssuch asanti-
histamine.
GENERAL PREVENTION OF SHOCK
28/11/2014CRITICAL CARE52
 Elevatethefoot of thebed to maintain agood
blood supply to thevital organ eg;- brain cells
 Replacement of lost fluidsby infusion or
transfusion.
 Administer oxygen if cyanosisismarked.
 In caseof trauma, giveanalgesic for pain.
CONTINUE
Identify and control sourceof infection
Administer antibiotic
 Removerisk factor for infection
01/09/15CRITICAL CARE53
28/ 11/ 2014CRITICAL CARE54
References
28/ 11/ 2014CRITICAL CARE55
Silverman, Adam (Oct 2005). "Shock: A Common Pathway For Life-
Threatening Pediatric Illnesses And Injuries". Pediatric Emergency
Medicine Practice 2 (10).
Tintinalli, Judith E. (2010). Emergency Medicine: A Comprehensive Study
Guide (Emergency Medicine (Tintinalli)). New York: McGraw-Hill
Companies. pp. 165–172. ISBN 0-07-148480-9. Marino, Paul L.
(September 2006). The ICU Book. Lippincott Williams & Wilkins,
Philadelphia & London. ISBN 0-7817-4802-X.
Tintinalli, Judith E. (2010). Emergency Medicine: A Comprehensive Study
Guide (Emergency Medicine (Tintinalli)). New York: McGraw-Hill
Companies. pp. 174–175. ISBN 0-07-148480-9.
Tintinalli, Judith E. (2010). Emergency Medicine: A Comprehensive Study
Guide (Emergency Medicine (Tintinalli)). New York: McGraw-Hill
Companies. ISBN 0-07-148480-9.
THANKS FOR
LISTERNING
01/09/15CRITICAL CARE56

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SHOCK

  • 1. 28/11/2014CRITICAL CARE 1 DEPARTMENT OF NURSING DONE BY: RN, BSc.N ABDULLA K NGWALI SECOND YEAR, SEMISTER ; 1 LECTURE; RAHMA JARUFE
  • 3. TOPIC: CARDIOVASCULAR SYSTEM SUB TOPIC: SHOCK 28/11/2014CRITICAL CARE3
  • 4. Learning objectives’- 28/11/2014CRITICAL CARE4  At theend of thissession every leaner should beableto understand thefollowing:-  Define shock  List thestageof shock  Describetypesof shock with its causes, sign  and symptoms.  Explain thepath physiology of shock  List sign & symptomsof theshock in general.  Mention thecomplication of shock.  DescribeManagement & treatment of shock
  • 5. Definition  Shock isaseriousmedical condition where thetissueperfusion isinsufficient to meet demand for oxygen and nutrition becausethe body isnot getting enough blood flow. Shock often accompaniessevereinjury / illness. OR  Isalifethreatening condition that occurs when thebody isnot getting enough blood flow. Zanzibar university
  • 6. continue 28/11/2014CRITICAL CARE6 OR  Isasudden fall in theblood passing through the tissuesof thevital organ.
  • 7. STAGE OF SHOCK 28/11/2014CRITICAL CARE7  Thefollowing stageincreaseyour chancesof developing shock: (a) “PRE- SHOCK” (b) SHOCK (c) “END ORGAN DYSFUNCTION”
  • 8. Continue 28/ 11/ 2014CRICAL CARE8 (a) “PRE- SHOCK” Body isableto compensatefor decrease perfusion up to 10% reduction n blood volume.
  • 9. continue 28/11/2014CRITICAL CARE9 (b) “SHOCK” Compensatory mechanism overwhelmed see signs(symptomsof organ dysfunction) 20-25% reduction in blood volume. (c) “ENDORGAN DYSFUNCTION” Learning to irreversibleorgan damageor death.
  • 10. Types of shock 28/11/2014CRITICAL CARE10  Shock can bedivided into: A. Hypovolemic shock B. Cardiogenic shock C. Obstructive shock D. Distributiveshock They are;- ( !) Sepsis (2) Neurogenic (spinal shock) (3) Anaphylaxis (4) Electricity
  • 11. (A). Hypovolemic shock 28/11/2014CRITICAL CARE11  Hypovolemic shock (caused by inadequate blood volume) Hypovolemic shock isan emergency condition in which severeblood and fluid lossmakestheheart unableto pump enough blood to thebody. Thistypeof shock can causemany organsto stop working.
  • 12. 28/ 11/ 2014CRITICAL CARE12  Itsprimary causeishemorrhagedueto trauma (internal and/or external), or lossof fluid from the circulation and vomiting and diarrhea arethe most common causein children. With other causesincluding burns. Cause of hypovolemic shock
  • 13. SIGN AND SYMPTOMS 28/11/2014. CRITICAL CARE13  A rapid, weak, thread pulsedueto decreased blood flow combined with tachycardia.  Cool, clammy skin due to stimulation of vasoconstriction.  Rapid and shallow breathing dueto sympathetic nervoussystem stimulation and acidosis
  • 14. Continue 28/11/2014CRITICAL CARE14 Hypothermia dueto decreased perfusion and evaporation of sweat. Thirst and dry mouth, dueto fluid depletion.
  • 15. {B} Cardiogenic shock 28/11/2014CRITICAL CARE15 Cardiogenic shock isadiseasestatewherethe heart isdamaged enough that it isunableto supply sufficient blood to thebody.
  • 16.
  • 17. Sign and symptoms 28/ 11/ 2014CRITICAL CARE17  Distended jugular veins dueto increased  jugular venouspressure.  Weak or absent pulse.  Arrhythmia often  Tachycardia.
  • 18. CAUSES OF CARDIOGENIC SHOCK 28/11/2014CRITICAL CARE18  Cardiogenic shock iscaused by thefailureof the heart to pump effectively.  Thiscan bedueto damageto theheart muscle, most often from alargemyocardial infarction.  Cardiomyopathy /myocarditis  Congestiveheart failure(CHF)  Cardiac valve problems.
  • 19. OBSTUCTIVE SHOCK  Isdueto obstruction of blood flow outsideof theheart. Several conditionscan result in thisform of shock. 01/09/15CRITICAL CARE19
  • 20. Causes of obstructive shock  Cardiac tamponade in which fluid in thepericardium preventsinflow of blood into theheart (venousreturn). Constrictivepericarditis in which thepericardium shrinks and hardens, issimilar in presentation.  Tension pneumothorax Through increased intrathoracic pressure, blood flow to theheart isprevented (venous return). 01/09/15CRITICAL CARE20
  • 21. continue  Pulmonary embolism istheresult of a thromboembolic incident in theblood vesselsof thelungs and hindersthereturn of blood to the heart.  Aortic stenosishinderscirculation by obstructing theventricular outflow tract. 01/09/15CRITICAL CARE21
  • 22. Sign and symptoms of obstructive Low blood pressure Lack of oxygen to body tissue Clammy skin Cool skin. 01/09/15CRITICAL CARE22
  • 23. {C} DISTRIBUTIVE SHOCK 28/11/2014CRITICAL CARE23 Isdueto impaired utilization of oxygen and thus production of energy by thecell. Distributiveshock includethefollowing;-  Septic  Anaphylactic,  Neurogenic,  Electricity
  • 24. Causes of distributive shock  It can becaused by;-  Systematic Inflammatory ResponseSyndrome (SIRS)  Dueto conditionsother than infection such as pancreatitis,burns, or trauma. 01/09/15CRITICAL CARE24
  • 25. continue  Toxic Shock Syndrome(TSS)  Anaphylaxis(A sudden ,severeallergic reaction)  Reactionsto drug or toxins.  Hepatic (Liver) insufficiency and damageto the( CNS) 01/09/15CRITICAL CARE25
  • 26. Sign and symptoms of distributive Temperature<36 OR > 38 Heart rate>90 beatsper minutes Respiratory Rate>20bmin 01/09/15CRITICAL CARE26
  • 27. {a} SEPTIC SHOCK 28/11/2014CRITICAL CARE27  Septic shock ( associated with infections) Septic shock isaseriouscondition that occurs when an overwhelming infection leadsto low blood pressureand low blood flow. Thebrain, heart, kidneys, and liver may not work properly or may fail.
  • 29. CAUSES OF SEPTIC 28/11/2014CRITICAL CARE29  Septic shock can becaused by ;- 1) Gram negative  Bacteriasuch as(among others) Escherichia co li, Proteusspecies, klebsiela, pneumo niae which releasean endotoxin which produces adverse biochemical,  Immunological and occasionally neurological effects which are harmful to the body.
  • 30. Continue 28/ 11/ 2014CRITICAL CARE30 2) Gram-positive  Cocci such aspneumococci and  Streptococci and certain fungi aswell asGram- positive bacterial toxins.  Septic shock also includessomeelements of cardiogenic shock.
  • 31. Symptoms of septic shock  Symptomsare: similar to hypovolaemic shock except in thefirst stages: Pyrexiaand fever, or hyperthermia, dueto overwhelming bacterial infection.  Vasodilation and increased cardiac output due to sepsis. 01/09/15CRITICAL CARE31
  • 32. (b) Anaphylactic shock 28/11/2014CRITICAL CARE32  Is a type of severe hypersensitivity or allergic reaction.
  • 34. causes 28/11/2014CRITICAL CARE34  Causesinclude;-  Allergy to insect stings, medicines, or foods (nuts, and seafood), etc.
  • 35. Sign and symptoms of anaphylactic  Polyuria,  Respiratory distress, hypotension (low blood pressure),  Encephalitis, fainting, unconsciousness,  Urticaria(hives),  Angioedema(swelling of thelips, face, neck and throat), Tears(dueto angioedemaand stress),  Vomiting, itching,  Anxiety, 01/09/1535 CRITICAL CARE
  • 36. (d) Electrical Shock 28/11/201436  Isthephysiological reaction or injury caused by electric current passing through thehuman body. OR  An electric current that passesthrough thebody is also called ashock.  And it can beso dangerous but electrical shock isdifferent from themedical shock discussed .
  • 38. Continue 28/11/2014CRITICAL CARE38 In electric shock Oxygen isroutinely given, to the victim and somepeopleneed to beput on a ventilator (abreathing machine) to increasethe amount of oxygen getting to their cells.
  • 39. Causes Electrical causecan causeinjuriesincluding burnsand disturbancesto heart rhythm (heart failure) that could befatal. 01/09/15critical care39
  • 40. Sign and symptoms  Unconsciousness.  Burns, particulary entranceand exit burns( wheretheelectricity entered and left thebody.)  Difficult in beathing or n breathing at all.  Sudden onset of cardiac arrest. 01/09/15CRITICAL CARE40
  • 41. PATHOPHYSIOLOGY OF SHOCK Cellsswitch from aerobic to anaerobic metabolism Lactic acid production Cell function ceasesand swells Membranebecomesmorepermeable Electrolytesand fluidsseepsin &out of cell. 01/09/15CRITICAL CARE41
  • 42. continue Na and K pump impaired 01/09/15CRITICAL CARE42 Mitochondria damage cells death
  • 44. Sign and symptoms in general types  ) Rapid respiration 2) Cold and clammy skin, 3) A weak but rapid pulse, 4) Fall in blood pressure, dueto reduction of blood volume  5) Weaknessall over thebody. 6) Dizzy, confused, and may becomeunconscious. Intensivethirsty dueto lossof water 01/09/1544
  • 45. GENERAL COMPLICATION OF SHOCK 28/1/2014CRITICAL CARE45  Kidney disease  Liver disease  Intestinal ischemia  Stroke  Disseminated intravascular coagulation (DIC)
  • 46. Continue 28/11/2014CRITICAL CARE46  Respiratory failure  Heart failure  Death
  • 47. Managements and Treatments shock 28/11/2014CRITICAL CARE47  Airway  breathing  Circulation  Treatmentsof shock alwaysshould beaimed to correct thecauseof shock and helping physiological compensatory mechanism to restore thetissueperfusion.
  • 48. continue  Themain goalsof thetreatment of cardiogenic shock arethere-establishment of circulation to the myocardium, minimising heart muscledamageand improving theheart’seffectivenessasapump.  Oxygen (O2) therapy to reducestheworkload of theheart by reducing tissuedemandsfor blood flow.  Administration of cardiac drugs 01/09/15CRITICAL CARE48
  • 49. Continue  Increaseheart’spumping action and decrease work load of theheart through medication such as Dopamine, dobutamine, epinephrine, norepinephrine.  Nitroglycerineuseful only if cardiogenic shock accompanied by appropriate  Dosage10mg-min 6ml-hr increaseby 10mg – min every 5-10min to achieveoptimal effect. 01/09/15CRITICAL CARE49
  • 50. Continue 28/11/2014CRITICAL CARE50  So dueto thisreason shock istreated dueto under lying causesof it if whether ishemorrhagic, or Hypovolemic or anaphylactic  In all typesof shock restoration of arterial pressureisessential to maintain perfusion and blood flow to thebrain.
  • 51. continue 28/11/2014CRITICAL CARE51  Peoplein shock should betaken by ambulance to ahospital asquickly aspossible. then, they should bekept lying down on their back with their feet raised about afoot higher than their head.  Administer counter-mediatorssuch asanti- histamine.
  • 52. GENERAL PREVENTION OF SHOCK 28/11/2014CRITICAL CARE52  Elevatethefoot of thebed to maintain agood blood supply to thevital organ eg;- brain cells  Replacement of lost fluidsby infusion or transfusion.  Administer oxygen if cyanosisismarked.  In caseof trauma, giveanalgesic for pain.
  • 53. CONTINUE Identify and control sourceof infection Administer antibiotic  Removerisk factor for infection 01/09/15CRITICAL CARE53
  • 55. References 28/ 11/ 2014CRITICAL CARE55 Silverman, Adam (Oct 2005). "Shock: A Common Pathway For Life- Threatening Pediatric Illnesses And Injuries". Pediatric Emergency Medicine Practice 2 (10). Tintinalli, Judith E. (2010). Emergency Medicine: A Comprehensive Study Guide (Emergency Medicine (Tintinalli)). New York: McGraw-Hill Companies. pp. 165–172. ISBN 0-07-148480-9. Marino, Paul L. (September 2006). The ICU Book. Lippincott Williams & Wilkins, Philadelphia & London. ISBN 0-7817-4802-X. Tintinalli, Judith E. (2010). Emergency Medicine: A Comprehensive Study Guide (Emergency Medicine (Tintinalli)). New York: McGraw-Hill Companies. pp. 174–175. ISBN 0-07-148480-9. Tintinalli, Judith E. (2010). Emergency Medicine: A Comprehensive Study Guide (Emergency Medicine (Tintinalli)). New York: McGraw-Hill Companies. ISBN 0-07-148480-9.