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(the energy producing stage(
 a) The 2 molecules of glyceroaldehyde-3-
phosphate are converted into pyruvate (aerobic
glycolysis) or lactate (anaerobic glycolysis).
 b) These steps produce ATP molecules (energy
production).
 the aldehyde group of glyceraldehyde-3-PO4
is oxidized to a carboxyl group and esterified
with inorganic phosphate to form the high-
ehergy compound 1,3-biphosphoglycerate.
The reaction is catalyzed by glyceraldehyde-
3-PO4 dehydrogenase, during w/c NAD+ is
reduced to NADH
Phosphoglycerate kinase catalyzes the
phosphorylation of ADP by the high-energy
compound 1,3-biphosphoglycerate to form
ATP and 3-phosphoglycerate.
 Phosphoglyceromutase catalyzes the
rearrangement of 3-phosphoglycerate into 2-
phosphoglycerate
 Enolase then catalyzes the dehydration of 2-
phosphoglycerate to yield the
phosphorylated enol form of pyruvate,
phosphoenolpyruvate, the second high-
energy compound produced by the glycolytic
process.
 ADP is then enzymatically phosphorylated by
pyruvate kinase, and the enol form of
pyruvate rapidly rearranges
nonenzymatically to the keto form of
pyruvate
 NAD+ is regenerated by the reduction of
pyruvate to lactate catalyzed by lactic
dehydrogenase.
 is a process that generates  NADPH
and pentoses.
 There are two distinct phases in the
pathway.
-the first is the oxidative phase, in which
NADPH is generated, and the second is the
non-oxidative synthesis of 5-carbon sugars.
 This pathway is an alternative to glycolysis. 
 its primary role is anabolic (constructive
metabolism) rather than catabolic
(destructive metabolism)
 After glycolysis, the catabolism of glucose
continues with the entry of pyruvate into the
mitochondria. There, the pyruvate is oxidatively
transformed into acetyl-s-CoA, w/c is
subsequently oxidized in the citric acid cycle.

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Second stage of Glycolysis

  • 2.  a) The 2 molecules of glyceroaldehyde-3- phosphate are converted into pyruvate (aerobic glycolysis) or lactate (anaerobic glycolysis).  b) These steps produce ATP molecules (energy production).
  • 3.  the aldehyde group of glyceraldehyde-3-PO4 is oxidized to a carboxyl group and esterified with inorganic phosphate to form the high- ehergy compound 1,3-biphosphoglycerate. The reaction is catalyzed by glyceraldehyde- 3-PO4 dehydrogenase, during w/c NAD+ is reduced to NADH
  • 4. Phosphoglycerate kinase catalyzes the phosphorylation of ADP by the high-energy compound 1,3-biphosphoglycerate to form ATP and 3-phosphoglycerate.
  • 5.  Phosphoglyceromutase catalyzes the rearrangement of 3-phosphoglycerate into 2- phosphoglycerate
  • 6.  Enolase then catalyzes the dehydration of 2- phosphoglycerate to yield the phosphorylated enol form of pyruvate, phosphoenolpyruvate, the second high- energy compound produced by the glycolytic process.
  • 7.  ADP is then enzymatically phosphorylated by pyruvate kinase, and the enol form of pyruvate rapidly rearranges nonenzymatically to the keto form of pyruvate
  • 8.  NAD+ is regenerated by the reduction of pyruvate to lactate catalyzed by lactic dehydrogenase.
  • 9.
  • 10.  is a process that generates  NADPH and pentoses.  There are two distinct phases in the pathway. -the first is the oxidative phase, in which NADPH is generated, and the second is the non-oxidative synthesis of 5-carbon sugars.  This pathway is an alternative to glycolysis.   its primary role is anabolic (constructive metabolism) rather than catabolic (destructive metabolism)
  • 11.
  • 12.  After glycolysis, the catabolism of glucose continues with the entry of pyruvate into the mitochondria. There, the pyruvate is oxidatively transformed into acetyl-s-CoA, w/c is subsequently oxidized in the citric acid cycle.