Scabies is caused by the scabies mite Sarcoptes scabiei that burrows into the skin. It spreads through prolonged skin-to-skin contact. Clinical features include intense itching and skin burrows typically found on fingers, wrists, armpits and genitals. Diagnosis is made by finding mites, eggs or feces in skin scrapings under microscopy. Treatment involves topical scabicides like permethrin or oral ivermectin applied to the entire body along with treating contacts to eliminate reinfestation. Crusted or Norwegian scabies occurs in immunocompromised individuals with thick scales and crusts over large areas of the body and is highly
Warts are growths on the skin caused by an infection with the human papilloma virus, or HPV. Types of warts include:
-- Common warts (often appear on the fingers)
-- Plantar warts (often appear on the soles of the feet)
-- Genital warts (sexually transmitted diseases)
-- Flat warts (usually appear in places where one shaves frequently)
In children, warts often go away on their own. In adults, however, they tend to stay. Warts are often removed for cosmetic reasons or to eliminate discomfort.
http://www.nlm.nih.gov/medlineplus/ency/article/000885.htm
Fungal skin infections are commonly affect the outer layer of the skin, nails and hair. Most of the fungi causing infections are usually dermatophytes (tinea), yeast (candida) and molds
Warts are growths on the skin caused by an infection with the human papilloma virus, or HPV. Types of warts include:
-- Common warts (often appear on the fingers)
-- Plantar warts (often appear on the soles of the feet)
-- Genital warts (sexually transmitted diseases)
-- Flat warts (usually appear in places where one shaves frequently)
In children, warts often go away on their own. In adults, however, they tend to stay. Warts are often removed for cosmetic reasons or to eliminate discomfort.
http://www.nlm.nih.gov/medlineplus/ency/article/000885.htm
Fungal skin infections are commonly affect the outer layer of the skin, nails and hair. Most of the fungi causing infections are usually dermatophytes (tinea), yeast (candida) and molds
Scabies is a superficial epidermal infestation by the mite Sarcoptes scabiei var. hominis.
Etiologic Agent:
S. scabiei var. hominis. Thrive and multiply only on human skin, i.e., obligate human parasite.
Transmission
Skin-to-skin contact
Fomites: Mites can remain alive for >2 days on clothing or in bedding; hence, scabies can be acquired without skin-to-skin contact.
intimate personal contact, such as having sexual intercourse
Scabietic (Scabious) Nodule:Inflammatory papule or nodule ;burrow sometimes seen on the surface of a very early lesion.• Distribution : Areola, axillae, scrotum, penis.
This is a seminar conducted by 4th year medical student under supervision of a lecturer. Sorry for not attaching the references.
Information were from few textbooks, google and also from previous dermatology posting group's seminar.
Scabies
Causative organism: Sarcoptes scabiei var. hominis (Itch mite).
Highly contagious disease
spreads in households and environments where there is intimate personal contact
Transmitted through infected clothes, linens and sexual contacts.
PATHOGENESIS
CLASSIFICATION
Classical
Nodular scabies
Crusted (Norwegian) scabies
Bullous scabies
PREDISPOSING FACTORS
Lack of hygiene
Low socioeconomic conditions
Close physical contacts
Immunocompromisation
Vagabond
Old age
Hospital stay
Down syndrome, Organ transplant, Leukemia, AIDS patients
CLINICAL FEATURES
Pathognomonic lesion:
Burrow which is slightly elevated, greyish and tortuous lines. Vesicle or pustule containing the mite may be found found at the end of the burrow
(Definition: a linear or curvilinear papule, caused by a burrowing scabies mite)
Papules, excoriations, bulla, crust and lichenification occurs.
Pruritus is prominent symptom which is severe and usually more intense in the night.
Even after successful treatment, itch can continue and occasionally nodular lesions persist.
SITES
Finger webs
Wrists
Axilla
Nipple and Areola
Umbilicus
Lower abdomen
Genitalia
Buttock
Scrotum and penis
Face and scalp in infant
Around and underneath nails
Involvement of the genitals in males and of the nipples in females are pathognomic.
COMPLICATIONS
Local:
Secondary bacterial infections – impetigo, folliculitis, furunculosis.
Eczematization
systemic: acute glomerulonephritis
INVESTIAGATIONS
The diagnosis is made by identifying the scabietic burrow and visualizing the mite (by extracting with a needle under microscope or using a dermatoscope).
Burrow is detected with gentian violet and then the organism is isolated with needle or scalpel and visualized under microscope.
TREATMENT
General measures
Counselling and reassurance
Maintenance of personal hygiene
Treatment of family members and close contacts at a time.
Washing of clothes and beddings.
Specific measures
Topical therapy
1.5% permethrin cream – 2 applications 1 week apart., Apply all over the body (except head and face in adults) and keep it for 8 to 12 hours. Then wash off .
All family members and physical contacts need to apply in the same way at same time.
2.25% Benzyl benzoate
3.Crotamiton 10% cream
4.10% precipitated sulphur
5.Malathion
6.Lindane
7.Monosulfirum
Systemic therapy
Ivermectin: single dose in case of severe infestation and in immunosuppressed patients.
Pediculosis capitis
Pediculosis corporis
Pediculosis pubis
Three types of lice:
Head lice: Pediculus humanus capitis (2-3 mm long)
Body lice: Pediculus humanus humanus (2.3-3.6 mm long)
Pubic lice (crabs): Phthirus pubis (1.1-1.8 mm long)
Sites of predilection
Head lice nearly always confined to scalp, especially occipital and postauricular regions.
Rarely, head lice infest beard or other hairy sites. Although more common with crab lice, head lice can also infest the eyelashes ( pediculosis palpebrarum ).
INTRODUCTION OF PSORIASIS, EPIDEMIOLOGY OF PSORIASIS, CLINICAL FEATURES OF PSORIASIS, PROGNOSIS OF PSORIASIS, HISTOPATHOLOGY OF PSORIASIS, TRIGGERING FACTORS OF PSORIASIS, PATHOGENESIS OF PSORIASIS
Pigmentation disorders of skin dermatology revision notesTONY SCARIA
dermatology revision notes for neet pg preparation based on lecture notes with high yield topic & last minute revision notes based on previous year questions
Scabies is a superficial epidermal infestation by the mite Sarcoptes scabiei var. hominis.
Etiologic Agent:
S. scabiei var. hominis. Thrive and multiply only on human skin, i.e., obligate human parasite.
Transmission
Skin-to-skin contact
Fomites: Mites can remain alive for >2 days on clothing or in bedding; hence, scabies can be acquired without skin-to-skin contact.
intimate personal contact, such as having sexual intercourse
Scabietic (Scabious) Nodule:Inflammatory papule or nodule ;burrow sometimes seen on the surface of a very early lesion.• Distribution : Areola, axillae, scrotum, penis.
This is a seminar conducted by 4th year medical student under supervision of a lecturer. Sorry for not attaching the references.
Information were from few textbooks, google and also from previous dermatology posting group's seminar.
Scabies
Causative organism: Sarcoptes scabiei var. hominis (Itch mite).
Highly contagious disease
spreads in households and environments where there is intimate personal contact
Transmitted through infected clothes, linens and sexual contacts.
PATHOGENESIS
CLASSIFICATION
Classical
Nodular scabies
Crusted (Norwegian) scabies
Bullous scabies
PREDISPOSING FACTORS
Lack of hygiene
Low socioeconomic conditions
Close physical contacts
Immunocompromisation
Vagabond
Old age
Hospital stay
Down syndrome, Organ transplant, Leukemia, AIDS patients
CLINICAL FEATURES
Pathognomonic lesion:
Burrow which is slightly elevated, greyish and tortuous lines. Vesicle or pustule containing the mite may be found found at the end of the burrow
(Definition: a linear or curvilinear papule, caused by a burrowing scabies mite)
Papules, excoriations, bulla, crust and lichenification occurs.
Pruritus is prominent symptom which is severe and usually more intense in the night.
Even after successful treatment, itch can continue and occasionally nodular lesions persist.
SITES
Finger webs
Wrists
Axilla
Nipple and Areola
Umbilicus
Lower abdomen
Genitalia
Buttock
Scrotum and penis
Face and scalp in infant
Around and underneath nails
Involvement of the genitals in males and of the nipples in females are pathognomic.
COMPLICATIONS
Local:
Secondary bacterial infections – impetigo, folliculitis, furunculosis.
Eczematization
systemic: acute glomerulonephritis
INVESTIAGATIONS
The diagnosis is made by identifying the scabietic burrow and visualizing the mite (by extracting with a needle under microscope or using a dermatoscope).
Burrow is detected with gentian violet and then the organism is isolated with needle or scalpel and visualized under microscope.
TREATMENT
General measures
Counselling and reassurance
Maintenance of personal hygiene
Treatment of family members and close contacts at a time.
Washing of clothes and beddings.
Specific measures
Topical therapy
1.5% permethrin cream – 2 applications 1 week apart., Apply all over the body (except head and face in adults) and keep it for 8 to 12 hours. Then wash off .
All family members and physical contacts need to apply in the same way at same time.
2.25% Benzyl benzoate
3.Crotamiton 10% cream
4.10% precipitated sulphur
5.Malathion
6.Lindane
7.Monosulfirum
Systemic therapy
Ivermectin: single dose in case of severe infestation and in immunosuppressed patients.
Pediculosis capitis
Pediculosis corporis
Pediculosis pubis
Three types of lice:
Head lice: Pediculus humanus capitis (2-3 mm long)
Body lice: Pediculus humanus humanus (2.3-3.6 mm long)
Pubic lice (crabs): Phthirus pubis (1.1-1.8 mm long)
Sites of predilection
Head lice nearly always confined to scalp, especially occipital and postauricular regions.
Rarely, head lice infest beard or other hairy sites. Although more common with crab lice, head lice can also infest the eyelashes ( pediculosis palpebrarum ).
INTRODUCTION OF PSORIASIS, EPIDEMIOLOGY OF PSORIASIS, CLINICAL FEATURES OF PSORIASIS, PROGNOSIS OF PSORIASIS, HISTOPATHOLOGY OF PSORIASIS, TRIGGERING FACTORS OF PSORIASIS, PATHOGENESIS OF PSORIASIS
Pigmentation disorders of skin dermatology revision notesTONY SCARIA
dermatology revision notes for neet pg preparation based on lecture notes with high yield topic & last minute revision notes based on previous year questions
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Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
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Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
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Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
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Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
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Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
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3. Scabies is a highly contagious infestation of humans and other mammals
caused by the itch mite Sarcoptes scabiei.
Scabies has the distinction of being the first human disease proven to be
caused by pathogen
4. Scabies is caused by Sarcoptes scabiei var. hominis.
Physiological variants of the same species cause ‘mange’ in other
mammals, like dogs, cats, cattle, rabbits, pigs and horses. Mites of one
animal do not cause established infestations on other animals or humans.
Humans may contact animal scabies but the infestation is mild and dies
out spontaneously.
The size of the male and female mites are about .2mm and .4mm
respectively. Oval in shape, they are ventrally flattened and have a
convex dorsal surface.
Itch mite have four pairs of legs.
5.
6. A newly fertilized female is usually the initiator of the infestation.
The female mite immediately starts digging a tunnel in the horny layer of
the skin and remains in the burrow for the rest of its life thriving on the
host lymph and lysed tissue.
The female mites lay eggs at the rate of 2 to 3 eggs per day for 6 to 8
weeks.
7. The eggs hatch out in 3-4 days , pierce the roof of the burrow and after
the larval and a few molts in the nymphal stage , becomes adult.
Mating takes place on the surface of the skin and the male dies.
It takes about two weeks for an egg to develop into a graved female.
8.
9. An affected host harbors about 11 to 12 gravid female mites.
A delayed hypersensitivity reaction (type IV) to the mites, their eggs or
feces develops approximately 4 weeks after the infestation.
This is responsible for the intense itching. A person with a past history of
scabies can develop immediate pruritus on re-infestation.
10. How to spread
The disease is spread from an infested person to another
by close personal and prolonged contact, including sexual
transmission.
Prolonged hand-holding and sleeping together facilitates
transmission particularly among family members,
playmates, and inmates of institutions and dormitories.
Overcrowding and associated poverty and poor hygiene
helps transmission.
Transmissions through fomites (clothing, linens towels) may
occur but are not considered significant modes of spread.
12. Scabies occurs in all populations. It is particularly prevalent in the
developing countries.
Children younger than 15 years of age have the highest prevalence.
After an incubation period of about 4 weeks the disease manifests itself
with its most characteristic symptom: severe itching with nocturnal
exacerbation.
The patient may present with extensive pyoderma or infective eczema.
13. The pathognomonic lesion of scabies is the
burrow: short, straight or curved, slightly
elevated lesion which often has a vesicle at its
end . Burrows are typically found on the finger
webs, front of the wrists, axillae and genitalia.
Site:-finger web, wrist , axillae, gentalia
Intensely itchy papular and vesicular lesions
soon develop due to hypersensitivity and these
lesions may be generalized with predilections
for the nipple and areola in females, umbilical
regions, buttocks, groins and thighs.
14. The scalp, face and the palms and soles are usually spared sites in the
usual cases.
The lesions are readily infected with bacteria and impetigo, folliculitis,
oozing and crusting are very commonly seen as also localized or extensive
infective eczema.
18. Norwegian or crusted scabies:
this is an unusually severe and extensive variety of scabies that occurs in
immunocompromised individuals ( HIV infection, steroid therapy,
malignancies), mentally retarded persons ( particularly Down’s syndrome)
, and in old debilitated persons unable to respond to the infestation by
scratching.
Crusted scabies is characterized by thick scaling and crusted lesions on the
sites of preference of the mites. In contrast to the more usual variety of
the disease, the palms and soles may be affected and the nails may be
thickened and dystrophic. Facial involvement may also occur. The
condition may give rise to a generalized erythroderma. Thousand, even
millions of mites may be present in a patient.
Nodular scabies:
genital scabies in males may give rise to persistent papules and nodules
despite successful treatment of the infestation. Histologically, the nodules
may mimic a lymphoma.
19.
20.
21. Bullous scabies: bullae may occur in infants and immunocompromised
people.
Animal scabies: is characterized by absence of burrows since the animal
mites cannot adapt themselves to human skin.
Scabies in infants and in the very old: infantile scabies shows
involvement of palms and soles as well as the face and scalp. In the very
old, the trunk may be more severely infested.
Scabies incognito: inadvertent application of topical steroid may modify
the clinical picture of scabies.
Scabies in very clean individuals may show few lesions, thus confusion
may arise as to the true nature of the itch.
22.
23. Typical clinical features of itching with nocturnal exacerbation and
finding the burrows and papules and vesicles in the sites of preference.
History of scabies in close contacts is an important diagnostic feature.
The diagnosis may be confirmed by finding the mites, their eggs or
feces by scraping the burrows and examining under a microscope.
Visualization of the burrow may be aided by applying marker pen ink and
washing the excess with alcohol, or painting with tetracycline solution
which is retained on the burrow and examining under Wood’s light : the
burrows will fluoresce.
28. GENERAL ADVICES
Avoidance of contact with infested persons. In crusted scabies isolation of
the patient is very important.
Treatment of all close contacts.
Maintenance of good personal hygiene-washing of clothes in hot water and
drying it. Items that cannot be washed should be isolated from use for at
least 3 days.
Nail clipping is must.
Improvement of socio-economic conditions is associated with lowered
prevalence of scabies.
30. DRUGS CONC. MOA DIRECTION INDICATIONS & C/I S/E COMMENTS
Sulphur 6%
ointmen
t
suppresses
mite
proliferatio
n
After a preliminary
bath, the sulphur
ointment is
applied and
thoroughly rubbed
into the skin over
the whole body for
two or three
consecutive nights.
used only in situations
where adults
cannot tolerate
lindane, permethrin, or
ivermectin
C/I - HYPERSENSITIVITY
ICD messy,
malodourous,
stains clothes
CHEAP
Safe
alternative in
infants,
children,
and pregnant
Benzyl
benzoate
25%
emulsio
n
12.5%.
Benzyl
benzoat
e – for
children
Unknown Benzyl benzoate
should be applied
below the neck
three times within
24 hours without
an
intervening bath or
on successive days,
or separated by
intervals of a week
Effective in permethrin
resistant crusted
scabies.
Combination
with ivermectin in
Patients with relapses
after a single
treatment with
ivermectin
C/I - pregnant and
lactating women,
infants, and young
ICD , ACD,
CNS toxicity
CHEAP
31. Crotamiton 10%
cream
or
lotion
Unknown applied twice
daily for five
consecutive days
after bathing and
changing
clothes
ICD antipruritic
properties
Lindane
( ϒ-BHC)
1%
cream
or
lotion
Primarily acting
on nerve cell
Na
channel -
leads to
increased
excitability,
convulsions,
and death of
mite
A single six hour
application
CNS toxicity - headache,
nausea, dizziness,
vomiting,
restlessness, tremors,
disorientation,
weakness, twitching of
eyelids convulsions, and
death.
aplastic anaemia,
thrombocytopenia, and
pancytopenia
maximum
single dose
is
20 g for
adults.
3-day or
more
interval is
given if
used with
ivermectin.
Permethrin 5%
Cream
Or
Lotion
Primarily acting
on nerve cell
Na
channel -
leads to
increased
excitability,
convulsions,
and death of
applied
overnight once a
week for two weeks
to the entire body,
including the head
in infants. The
contact period is
about
eight hours
Contact dermatitis Low toxicity
rapidly
metabolised
by skin
esterases,
and
excreted in
urine