video on YouTube
https://www.youtube.com/watch?v=haGWnLpAgic
https://www.youtube.com/watch?v=haGWnLpAgic
Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2), previously known by the provisional name 2019 novel coronavirus (2019-nCoV)
2. GKM
Gene
SARS-COV 2 COVID-19
SARS-COV
MERS-COV
Middle East Respiratory Syndrome Coronavirus
2003 Civet cat HUMAN 8,098 Cases
774 death
9.6%Severe Acute Respiratory Syndrome Coronavirus
2012
Pangolin
HUMAN
Severe Acute Respiratory Syndrome Coronavirus 2
2,494 Cases
858 death
34%
26 Countries
27 Countries
2019
HUMAN
166 Countries
Camel
284,566 Cases
11,868 death
4.17%
3. GKM
Gene
+ss
plays the most important roles in viral attachment, fusion and entry, and it
serves as a target for development of antibodies, entry inhibitors and vaccines
endoplasmic reticulum
Golgi Bodies
ACE2
Spike
Membrane New Virus
New VirusReceptor-Binding-Domain (RBD)
4. GKM
Gene
Symptoms
Fever Cough
Headache Shortness of
breathLab Examinations
• normal or decreased total WBC count and decreased lymphocyte
count
• Increased of liver enzymes (AST, ALT)
• Increased LDH
• C-reactive protein (CRP) can be found
• D-dimer value is increased